The aim of the study was to evaluate quality of life (QL) of patients with rheumatoid arthritis (RA) in Saratov region. The study was conducted within the framework of the program MCSQL (multi-center study of quality of life). The work presents the results of an investigation of the center of Saratov. The subjects were 139 patients (117 women; 22 men) with a valid diagnosis of RA. Deteriorated QL indices were revealed in all the patients; these indices correlated with the duration and activity of the disease as well as with gender and age.