To identify predictors of ischemic stroke in patients with suspected non-ST elevation (NSTE) acute coronary syndrome (ACS) and to evaluate in-hospital and 1-year outcomes.
We analyzed 5842 patients with diagnosed NSTE ACS included in the multi-center Canadian ACS registries. Patients with in-hospital stroke (n=28, 0.5%) were compared to patients without stroke. Risk factors and short- and long-term outcome were evaluated.
Baseline characteristics of patients with and without stroke were similar except for a significantly higher proportion of women, higher rates of in-hospital CABG, and greater use of unfractionated heparin. Crude event rates were significantly higher in patients with stroke: in-hospital death 21.4% vs. 1.6% (p/=2 on admission (OR 2.87, 1.18-6.99, p=0.02). Stroke was an independent predictor of in-hospital death (OR 14.52, 4.57-46.12, p