The article deals with diagnostic peculiarities of neuropsychologic traits in individuals with previous exposure to industrial neurotoxic chemicals. Pilot studies demonstrated brain disorders characteristic for toxic (mercurial) and vascular (discirculatory) encephalopathies, justified necessity of neuropsychologic approach in occupational therapeutic diagnosis. The authors presented results of suggested scheme of neuropsychologic prompt screening aimed to reveal higher psychic functional disorders in individuals with occupational neurointoxications.