The established tense environmental situation in Krasnouralsk, Sverdlovsk Region, presents a serious threat to human health. Development of a medium-term municipal environmental program for a Krasnouralsk urban district provides solutions of environmental problems. The human health status and carcinogenic and non-carcinogenic risks from exposure to chemical substances polluting ambient air, drinking water, and soil have been assessed within the framework of the program. The findings have served as a basis for elaborating technological and sanitary-and-hygienic measures of the environmental program to assure human environmental safety.