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Effects of continuous combined hormone replacement therapy and clodronate on bone mineral density in osteoporotic postmenopausal women: a 5-year follow-up.
https://arctichealth.org/en/permalink/ahliterature142867
Source
Maturitas. 2010 Aug;66(4):423-30
Publication Type
Article
Date
Aug-2010
More detail
Author
Marjo Tuppurainen
Kirsi Härmä
Marja Komulainen
Vesa Kiviniemi
Heikki Kröger
Risto Honkanen
Esko Alhava
Jukka Jurvelin
Seppo Saarikoski
Author Affiliation
Department of Obstetrics and Gynecology, Kuopio University Hospital, Kuopio, Finland. marjo.tuppurainen@kuh.fi
Source
Maturitas. 2010 Aug;66(4):423-30
Date
Aug-2010
Language
English
Publication Type
Article
Keywords
Alkaline Phosphatase - metabolism
Bone Density - drug effects
Bone Density Conservation Agents - pharmacology - therapeutic use
Clodronic Acid - pharmacology - therapeutic use
Drug Therapy, Combination
Estradiol - pharmacology - therapeutic use
Estrogen Replacement Therapy
Estrogens - pharmacology - therapeutic use
Female
Femur - drug effects
Finland
Follow-Up Studies
Humans
Lumbar Vertebrae - drug effects - pathology
Middle Aged
Norethindrone - analogs & derivatives - pharmacology - therapeutic use
Osteoporosis, Postmenopausal - drug therapy - metabolism
Postmenopause
Prospective Studies
Abstract
To determine the effects of HRT with or without clodronate on bone mineral density (BMD) change and bone turnover markers.
Prospective, partly randomized trial.
Kuopio University Hospital, Finland.
167 osteoporotic women (61+/-2.7 years; T-score
PubMed ID
20547017
View in PubMed
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