Serum selenium concentration of 220 residents in 11 Astrakhan districts was investigated, the concentration range being 87-133 microg/l. The lowest values were typical for Krasnoyarsk district possessing sandy soils with low content of humus. The highest human selenium status was demonstrated for Volga delta with alluvial saturated salty soils. Correlation coefficient between serum selenium and soils selenium was +0.6226.