MRI is sensitive for joint inflammation, but its ability to separate subgroups of arthritis in children has been questioned. Infectious arthritis (IA), postinfectious arthritis (PA), transient arthritis (TA) and juvenile idiopathic arthritis (JIA) are subgroups that may need early, different treatment.
To determine whether MRI findings differ in IA, PA/TA and JIA in recent-onset childhood arthritis.
Fifty-nine children from a prospective study of incidence of arthritis (n?=?216) were, based on clinical and biochemical criteria, examined by MRI. Joint fluid, synovium, bone marrow, soft tissue and cartilage were scored retrospectively and analysed by Pearson chi-square test and logistic regression analysis.
Fifty-nine children had MRI of one station. IA was suggested by bone marrow oedema (OR 7.46, P?=?0.011) and absence of T1-weighted and T2-weighted low signal intensity synovial tissue (OR 0.06, P?=?0.015). Furthermore, soft-tissue oedema and reduced contrast enhancement in the epiphyses were more frequent in children with IA. JIA correlated positively with low signal intensity synovial tissue (OR 13.30, P?
Cites: J Bone Joint Surg Am. 1999 Dec;81(12):1662-7010608376