The author presents the results of analysis of the current scientific literature concerning the prevalence of otomycosis in conjunction with the original data obtained during observation of 1762 patients who applied for the medical aid to the Counseling Department of this Centre and the study of out-patient medical records. It was shown that ENT fungal infections make up an appreciable proportion in the structure of inflammatory ear pathology. Specifically, the prevalence of fungal otitis amounts to 25.23% of the total ENT morbidity. In addition, the major factors responsible for the development of otomycosis and its most characteristic clinical symptoms were revealed. The analysis of the spectrum of pathogenic agents contributing to the evolvement of fungal otitis was performed. It has demonstrated the ever increasing involvement of Candida non albicans strains in the development of chronic ENT inflammation. Various medicamental preparations for the treatment of fungal otitis are characterized with special reference to the composite agent ?andibiotic designed for the treatment of this pathology.