Prenatal smoke exposure is associated with airway inflammation and asthma in children. It also increases the risk of low birth weight (LBW). LBW is associated with decreased lung function independently of smoking.
To study the independent and joint effects of prenatal smoking and LBW on childhood asthma.
In 1996, all children aged 7 to 8 years in 3 cities in northern Sweden were invited to an International Study of Asthma and Allergy in Childhood questionnaire survey. This study focused on the follow-up of children aged 11 to 12 years, in which 3389 children (96%) participated. A subset of 2121 children underwent skin-prick testing. Self-reported physician-diagnosed asthma has been clinically validated.
Mean birth weight was 3360 g in children exposed to prenatal smoking and 3571 g in nonexposed children (P
Cites: Am J Respir Crit Care Med. 2001 Feb;163(2):429-3611179118
Cites: Am J Respir Crit Care Med. 2007 May 15;175(10):1078-8517290040