Non-melanoma skin cancer (NMSC) is the most common cancer world-wide, yet few studies have investigated the psychosocial implications of this disease. The current study provides an account of the distress experienced by patients with NMSC and the coping strategies they use to deal with the NMSC diagnosis. The results demonstrate that 19 % of the patients experience significant levels of psychological distress. Furthermore, those who engaged in avoidant coping strategies (specifically behavioural avoidance) were more likely to experience distress. These findings highlight the importance of further investigating this patient population, since patients report difficulties adjusting to this disease and its treatment.