Complex study of seropositivity of adult individuals and children to human herpes viruses of 6 types.
2322 individuals (1000 adults donors and 1322 children aged 1 - 17 years) residing in St. Petersburg were examined. Seropositivity to human herpes viruses types 1, 2, 4, 5, 6 and 8 was studied by enzyme immunoassay methods.
A high proportion of individuals seropositive to cytomegalovirus (CMV) and herpes simplex virus (HSV) as well as high frequency of simultaneous presence of antibodies against various types of human herpes virus (HHV) was detected. A clear tendency of increase with age of frequency of detection of antibodies against most HHV was detected. The sharpest increase of seropositivity to HSV, HHV-8, CMV, Epsetin-Barr virus (EBV) is noted in a group of 12 - 17 year old children, that is probably connected with activation of sexual transmission. The proportion ofseropositivity in this age group was: to HSV - 65%, HHV-6 - 13%, HHV-8 - 3.3%, CMV - 80%, EBV - 61.7% against 74.8%, 68.4%, 2.7%, 80.9%, 41.8% in donors, respectively.
Further studies determining temporal trends of population infection, connection ofseropositivity with frequency of manifest forms of infections, seropositivity of risk groups are needed.