Division of Urology, Department of Surgery, Mount Sinai Hospital and University of Toronto, Toronto, Ontario, Canada; Institute of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California.
To evaluate whether hormonal markers predict erectile dysfunction (ED) and symptoms of T deficiency syndrome (TDS), which are commonly found in the population of infertile men.
Retrospective study utilizing a prospectively maintained infertility database.
A tertiary referral center.
A total of 1,750 of 2,783 men presenting for evaluation of infertility between 1995 and 2010 completed validated questionnaires.
Androgen Deficiency in the Aging Male (ADAM) and Sexual Health Inventory for Men questionnaires were administered. Baseline risk factors for ED and TDS were also measured. Subjects underwent serum hormone evaluation for total T, calculated bioavailable T, sex hormone-binding globulin, E2, LH, FSH, and PRL.
Multivariable logistic regression modeling was used to determine the significance of hormonal markers in predicting ED (Sexual Health Inventory for Men score