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Cadmium exposure in pregnancy and lactation in relation to iron status

https://arctichealth.org/en/permalink/ahliterature63737
Source
American Journal of Public Health. 2002 Feb;92(2):284-287
Publication Type
Article
Date
Feb-2002
  1 website  
Author
Akesson, A
Berglund, M
Schütz, A
Bjellerup, P
Bremme, K
Vahter, M
Author Affiliation
Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden. agneta.akesson@imm.ki.se
Source
American Journal of Public Health. 2002 Feb;92(2):284-287
Date
Feb-2002
Language
English
Geographic Location
Sweden
Publication Type
Article
Keywords
Adult
Cadmium - metabolism - pharmacokinetics
Cadmium Poisoning - epidemiology - prevention & control
Female
Humans
Iron - deficiency
Lactation - metabolism
Maternal Age
Middle Aged
Multivariate Analysis
Parity
Placenta - metabolism
Pregnancy
Pregnancy Complications - epidemiology - metabolism
Prospective Studies
Regression Analysis
Research Support, Non-U.S. Gov't
Sweden - epidemiology
Abstract
OBJECTIVES: The purpose of this study was to determine the impact of iron status on cadmium dose among pregnant women. METHODS: Iron status and cadmium concentration in blood, urine, and placenta were determined among women followed for 2 years from early pregnancy. RESULTS: Blood cadmium and urinary cadmium were correlated with iron status throughout the study period. Urinary cadmium increased longitudinally among women with exhausted iron stores during their pregnancy. The increase in urinary cadmium with age was more pronounced in multiparous than in nulliparous women. CONCLUSIONS: Iron deficiency during pregnancy leads to increased cadmium absorption and body burden. Multiparous women exhibit additional increases with increasing age.
PubMed ID
11818307 View in PubMed
Online Resources
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