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Cardiorespiratory Fitness, Sedentary Behaviour and Physical Activity Are Independently Associated with the Metabolic Syndrome, Results from the SCAPIS Pilot Study.

https://arctichealth.org/en/permalink/ahliterature271307
Source
PLoS One. 2015;10(6):e0131586
Publication Type
Article
Date
2015
Author
Örjan Ekblom
Elin Ekblom-Bak
Annika Rosengren
Mattias Hallsten
Göran Bergström
Mats Börjesson
Source
PLoS One. 2015;10(6):e0131586
Date
2015
Language
English
Publication Type
Article
Keywords
Accelerometry
Humans
Metabolic Syndrome X - epidemiology - physiopathology
Middle Aged
Motor Activity
Odds Ratio
Physical Fitness
Pilot Projects
Prevalence
Sedentary lifestyle
Sweden - epidemiology
Abstract
Previous studies on the relation between lifestyle and the metabolic syndrome lack one or several aspects of the physical activity pattern in the analyses or cardiorespiratory fitness. Likewise, both uni- and triaxial accelerometry have been used, though, the predictive validity of these two modes has not been compared.
The aims of the present study were firstly to investigate the independent relation between cardiorespiratory fitness and physical activity pattern to the metabolic syndrome (MetS) and secondly to examine the predictive validity of uni- and triaxial accelerometry, respectively.
Data was extracted from the SCAPIS pilot study (n=930, mean age 57.7 yrs). Physical activity pattern was assessed by accelerometry. Cardiorespiratory fitness was estimated using cycle ergometry. MetS was defined per the Adult Treatment Panel III from the National Cholesterol Education Program definition.
Time spent sedentary (OR: 2.38, 95% CI: 1.54-4.24 for T3 vs T1), in light intensity (OR: 0.50, 95% CI: 0.28-0.90) and in moderate-to-vigorous activity (OR: 0.33, 95% CI: 0.18-0.61), as well as cardiorespiratory fitness (OR: 0.24, 95% CI:0.12-0.48), were all independently related to the prevalence of MetS after adjustment for potential confounders, fitness and/or the other aspects of the physical activity pattern. In addition, we found that triaxial analyses were more discriminant, with ORs farther away from the reference group and additional significant ORs.
The finding that several aspects of the physical activity pattern reveal independent relations to the MetS makes new possible targets for behaviour change of interest, focusing on both exercise and everyday life. When assessing the risk status of a patient, it is advised that triaxial accelerometry is used.
Notes
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PubMed ID
26120842 View in PubMed
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Concomitant Associations of Healthy Food Intake and Cardiorespiratory Fitness With Coronary Artery Calcium.

https://arctichealth.org/en/permalink/ahliterature302542
Source
Am J Cardiol. 2018 08 15; 122(4):560-564
Publication Type
Journal Article
Multicenter Study
Observational Study
Research Support, Non-U.S. Gov't
Date
08-15-2018
Author
Lena Gripeteg
Daniel Arvidsson
Elias Johannesson
Christel Larsson
Agneta Sjöberg
Oskar Angerås
Erika Fagman
John Brandberg
Örjan Ekblom
Göran Bergström
Mats Börjesson
Author Affiliation
Department of Food and Nutrition and Sport Science, University of Gothenburg, Gothenburg, Sweden. Electronic address: daniel.arvidsson@gu.se.
Source
Am J Cardiol. 2018 08 15; 122(4):560-564
Date
08-15-2018
Language
English
Publication Type
Journal Article
Multicenter Study
Observational Study
Research Support, Non-U.S. Gov't
Keywords
Calcium - metabolism
Cardiorespiratory fitness
Coronary Angiography - methods
Coronary Artery Disease - diagnosis - epidemiology - metabolism
Coronary Vessels - diagnostic imaging - metabolism
Eating - physiology
Female
Follow-Up Studies
Humans
Incidence
Male
Middle Aged
Pilot Projects
Prognosis
Prospective Studies
Risk factors
Sweden - epidemiology
Tomography, X-Ray Computed
Vascular Calcification - diagnosis - epidemiology - metabolism
Abstract
Conflicting findings remain regarding associations between lifestyle behaviors and coronary artery calcium (CAC). We investigated concomitant associations of healthy food intake and cardiorespiratory fitness (CRF) with CAC. Data from 706 men and women 50 to 64 years old from the Swedish SCAPIS pilot trial were analyzed. A CAC score was calculated using the Agatston method. A Healthy Food Index (HFI) was established using data from a web-based food frequency questionnaire. CRF was assessed from a bike exercise test. Regression analyses were performed with occurrence of CAC (dichotomous) and level of CAC score in patients with CAC (continuous) as outcomes. 58% had 0 CAC score. HFI was significantly associated with having no CAC (standardized coefficient ß?=?0.18, p
PubMed ID
29958710 View in PubMed
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The Daily Movement Pattern and Fulfilment of Physical Activity Recommendations in Swedish Middle-Aged Adults: The SCAPIS Pilot Study.

https://arctichealth.org/en/permalink/ahliterature270006
Source
PLoS One. 2015;10(5):e0126336
Publication Type
Article
Date
2015
Author
Elin Ekblom-Bak
Gustav Olsson
Örjan Ekblom
Björn Ekblom
Göran Bergström
Mats Börjesson
Source
PLoS One. 2015;10(5):e0126336
Date
2015
Language
English
Publication Type
Article
Keywords
Cardiovascular Diseases - prevention & control
Exercise
Female
Humans
Male
Middle Aged
Personal Satisfaction
Pilot Projects
Sedentary lifestyle
Self Report
Surveys and Questionnaires
Sweden
Abstract
Different aspects of the daily movement pattern--sitting, light intensity physical activity, and moderate- and vigorous intensity physical activity--have each independently been associated with health and longevity. Previous knowledge of the amount and distribution of these aspects in the general Swedish population, as well as the fulfilment rate of physical activity recommendations, mainly relies on self-reported data. More detailed data assessed with objective methods is needed. The aim of the study was to present descriptive data on the daily movement pattern in a middle-aged Swedish population assessed by hip-worn accelerometers. The cohort consisted of 948 participants (51% women), aged 50 to 64 years, from the Swedish CArdioPulmonary bioImage pilot Study. In the total sample, 60.5% of accelerometer wear time was spent sitting, 35.2% in light physical activity and 3.9% in moderate- and vigorous physical activity. Men and participants with high educational level spent a larger proportion of time sitting, compared to women and participants with low educational level. Men and participants with a high educational level spent more time, and the oldest age-group spent less time, in moderate- and vigorous physical activity. Only 7.1% of the study population met the current national physical activity recommendations, with no gender, age or education level differences. Assessment of all three components of the daily movement pattern is of high clinical relevance and should be included in future research. As the fulfilment of national physical activity recommendations is very low and sitting time is very high in our middle-aged population, the great challenge remains to enhance the implementation of methods to increase the level of physical activity in this population.
Notes
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PubMed ID
25970580 View in PubMed
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Non-alcoholic fatty liver disease is a strong predictor of coronary artery calcification in metabolically healthy subjects: A cross-sectional, population-based study in middle-aged subjects.

https://arctichealth.org/en/permalink/ahliterature298039
Source
PLoS One. 2018; 13(8):e0202666
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Date
2018
Author
Anders Gummesson
Ulf Strömberg
Caroline Schmidt
Joel Kullberg
Oskar Angerås
Stefan Lindgren
Ola Hjelmgren
Kjell Torén
Annika Rosengren
Björn Fagerberg
John Brandberg
Göran Bergström
Author Affiliation
Department of Clinical Pathology and Genetics, Sahlgrenska University Hospital, Gothenburg, Sweden.
Source
PLoS One. 2018; 13(8):e0202666
Date
2018
Language
English
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Keywords
Carotid Arteries - diagnostic imaging
Carotid Artery Diseases - diagnostic imaging - epidemiology
Cross-Sectional Studies
Female
Humans
Logistic Models
Male
Metabolic Syndrome - epidemiology
Middle Aged
Non-alcoholic Fatty Liver Disease - diagnostic imaging - epidemiology
Obesity - complications - epidemiology
Pilot Projects
Propensity Score
Risk factors
Sweden - epidemiology
Tomography Scanners, X-Ray Computed
Ultrasonography
Abstract
This study aims to estimate the relationship between non-alcoholic fatty liver disease (NAFLD) and measures of atherosclerotic cardiovascular disease (ASCVD), and to determine to what extent such relationships are modified by metabolic risk factors.
The study was conducted in the population-based Swedish CArdioPulmonary bioImage Study (SCAPIS) pilot cohort (n = 1015, age 50-64 years, 51.2% women). NAFLD was defined as computed tomography liver attenuation =40 Hounsfield Units, excluding other causes of liver fat. Coronary artery calcification score (CACS) was assessed using the Agatston method. Carotid plaques and intima media thickness (IMT) were measured by ultrasound. Metabolic status was based on assessments of glucose homeostasis, serum lipids, blood pressure and inflammation. A propensity score model was used to balance NAFLD and non NAFLD groups with regards to potential confounders and associations between NAFLD status and ASCVD variables in relation to metabolic status were examined by logistic and generalized linear regression models.
NAFLD was present in 106 (10.4%) of the subjects and strongly associated with obesity-related traits. NAFLD was significantly associated with CACS after adjustment for confounders and metabolic risk factors (OR 1.77, 95% CI 1.07-2.94), but not with carotid plaques and IMT. The strongest association between NAFLD and CACS was observed in subjects with few metabolic risk factors (n = 612 [60% of all] subjects with 0-1 out of 7 predefined metabolic risk factors; OR 5.94, 95% CI 2.13-16.6).
NAFLD was independently associated with coronary artery calcification but not with measures of carotid atherosclerosis in this cohort. The association between NAFLD and CACS was most prominent in the metabolically healthy subjects.
PubMed ID
30133541 View in PubMed
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Occupational exposure to vapor, gas, dust, or fumes and chronic airflow limitation, COPD, and emphysema: the Swedish CArdioPulmonary BioImage Study (SCAPIS pilot).

https://arctichealth.org/en/permalink/ahliterature294306
Source
Int J Chron Obstruct Pulmon Dis. 2017; 12:3407-3413
Publication Type
Journal Article
Date
2017
Author
Kjell Torén
Jenny Vikgren
Anna-Carin Olin
Annika Rosengren
Göran Bergström
John Brandberg
Author Affiliation
Section of Occupational and Environmental Medicine, Institute of Medicine, Sahlgrenska Academy.
Source
Int J Chron Obstruct Pulmon Dis. 2017; 12:3407-3413
Date
2017
Language
English
Publication Type
Journal Article
Keywords
Air Pollutants, Occupational - adverse effects
Chi-Square Distribution
Cross-Sectional Studies
Dust
Environmental monitoring
Female
Forced expiratory volume
Gases - adverse effects
Humans
Logistic Models
Lung - diagnostic imaging - drug effects - physiopathology
Male
Middle Aged
Occupational Diseases - chemically induced - diagnosis - epidemiology - physiopathology
Occupational Exposure - adverse effects
Occupational Health
Odds Ratio
Pilot Projects
Prevalence
Pulmonary Disease, Chronic Obstructive - chemically induced - diagnosis - epidemiology - physiopathology
Pulmonary Emphysema - chemically induced - diagnosis - epidemiology - physiopathology
Risk assessment
Risk factors
Spirometry
Surveys and Questionnaires
Sweden - epidemiology
Tomography, X-Ray Computed
Vital Capacity
Volatilization
Abstract
The aim of this study was to estimate the occupational burden of airflow limitation, chronic airflow limitation, COPD, and emphysema.
Subjects aged 50-64 years (n=1,050) were investigated with forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC). Airflow limitation was defined as FEV1/FVC
Notes
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PubMed ID
29238185 View in PubMed
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Validity of physician-diagnosed COPD in relation to spirometric definitions of COPD in a general population aged 50-64 years - the SCAPIS pilot study.

https://arctichealth.org/en/permalink/ahliterature291862
Source
Int J Chron Obstruct Pulmon Dis. 2017; 12:2269-2275
Publication Type
Journal Article
Validation Studies
Date
2017
Author
Kjell Torén
Nicola Murgia
Anna-Carin Olin
Jan Hedner
John Brandberg
Annika Rosengren
Göran Bergström
Author Affiliation
Section of Occupational and Environmental Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Source
Int J Chron Obstruct Pulmon Dis. 2017; 12:2269-2275
Date
2017
Language
English
Publication Type
Journal Article
Validation Studies
Keywords
Bronchitis, Chronic - diagnosis - epidemiology - physiopathology
Female
Forced expiratory volume
Humans
Lung - physiopathology
Male
Middle Aged
Pilot Projects
Predictive value of tests
Prevalence
Pulmonary Disease, Chronic Obstructive - diagnosis - epidemiology - physiopathology
Pulmonary Emphysema - diagnosis - epidemiology - physiopathology
Reproducibility of Results
Spirometry
Surveys and Questionnaires
Sweden - epidemiology
Vital Capacity
Abstract
In epidemiological studies, items about physician-diagnosed COPD are often used. There is a lack of validation and standardization of these items.
In a general population-based study, 1,050 subjects completed a questionnaire and performed spirometry, including forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) after inhalation of 400 µg of salbutamol. COPD was defined as the ratio of FEV1/FVC
Notes
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PubMed ID
28831247 View in PubMed
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6 records – page 1 of 1.