The aim of the study was to analyse effects of various innovative forms of school education on the health status and functional abilities of children and adolescents. Enhanced academic loads are shown to be the most unfavourable factor of the school environment. The main consequences of excess teaching load are shortened motor and outdoor activities of the children, smaller duration of night sleep. Optimization of academic routine (alternation of studies and holidays), modular structure of school calendar might help to reduce fatigue during school hours. Hygienic estimates of different variants of specialized education are obtained. Scientifically sound hygienic requirements are proposed to be applied to the organization of academic activities in a new type of educational institutions, full-day schools.