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1513 records – page 1 of 152.

A 2-year follow-up study of people with severe mental illness involved in psychosocial rehabilitation.

https://arctichealth.org/en/permalink/ahliterature257843
Source
Nord J Psychiatry. 2014 Aug;68(6):401-8
Publication Type
Article
Date
Aug-2014
Author
Petra Svedberg
Bengt Svensson
Lars Hansson
Henrika Jormfeldt
Author Affiliation
Petra Svedberg, Associate Professor, School of Social and Health Sciences, Halmstad University , Sweden.
Source
Nord J Psychiatry. 2014 Aug;68(6):401-8
Date
Aug-2014
Language
English
Publication Type
Article
Keywords
Adult
Female
Follow-Up Studies
Humans
Male
Mental Disorders - psychology - rehabilitation
Mental health services
Middle Aged
Power (Psychology)
Prospective Studies
Psychotherapy - methods
Quality of Life
Sweden
Treatment Outcome
Young Adult
Abstract
BACKGROUNDS. A focus on psychiatric rehabilitation in order to support recovery among persons with severe mental illness (SMI) has been given great attention in research and mental health policy, but less impact on clinical practice. Despite the potential impact of psychiatric rehabilitation on health and wellbeing, there is a lack of research regarding the model called the Psychiatric Rehabilitation Approach from Boston University (BPR).
The aim was to investigate the outcome of the BPR intervention regarding changes in life situation, use of healthcare services, quality of life, health, psychosocial functioning and empowerment.
The study has a prospective longitudinal design and the setting was seven mental health services who worked with the BPR in the county of Halland in Sweden. In total, 71 clients completed the assessment at baseline and of these 49 completed the 2-year follow-up assessments.
The most significant finding was an improved psychosocial functioning at the follow-up assessment. Furthermore, 65% of the clients reported that they had mainly or almost completely achieved their self-formulated rehabilitation goals at the 2-year follow-up. There were significant differences with regard to health, empowerment, quality of life and psychosocial functioning for those who reported that they had mainly/completely had achieved their self-formulated rehabilitation goals compared to those who reported that they only had to a small extent or not at all reached their goals.
Our results indicate that the BPR approach has impact on clients' health, empowerment, quality of life and in particular concerning psychosocial functioning.
PubMed ID
24228778 View in PubMed
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3D modeling-based surgical planning in transsphenoidal pituitary surgery--preliminary results.

https://arctichealth.org/en/permalink/ahliterature90794
Source
Acta Otolaryngol. 2008 Sep;128(9):1011-8
Publication Type
Article
Date
Sep-2008
Author
Raappana Antti
Koivukangas John
Pirilä Tapio
Author Affiliation
Department of Otorhinolaryngology, Head and Neck Surgery, Oulu University Hospital, Oulu, Finland. antti.raappana@oulu.fi
Source
Acta Otolaryngol. 2008 Sep;128(9):1011-8
Date
Sep-2008
Language
English
Publication Type
Article
Keywords
Adenoma - pathology - radiography - surgery
Adolescent
Adult
Aged
Endoscopy - methods
Feasibility Studies
Female
Humans
Imaging, Three-Dimensional
Magnetic Resonance Imaging
Male
Middle Aged
Models, Neurological
Pituitary Neoplasms - pathology - radiography - surgery
Prospective Studies
Surgery, Computer-Assisted - methods
Tomography, X-Ray Computed
Young Adult
Abstract
CONCLUSION: The preoperative three-dimensional (3D) modeling of the pituitary adenoma together with pituitary gland, optic nerves, carotid arteries, and the sphenoid sinuses was adopted for routine use in our institution for all pituitary surgery patients. It gave the surgeon a more profound orientation to the individual surgical field compared with the use of conventional 2D images only. OBJECTIVE: To demonstrate the feasibility of 3D surgical planning for pituitary adenoma surgery using readily available resources. SUBJECTS AND METHODS: The computed tomography (CT) and magnetic resonance imaging (MRI) data of 40 consecutive patients with pituitary adenoma were used to construct 3D models to be used in preoperative planning and during the surgery. A freely available, open source program (3D Slicer) downloaded to a conventional personal computer (PC) was applied. RESULTS: The authors present a brief description of the 3D reconstruction-based surgical planning workflow. In addition to the preoperative planning the 3D model was used as a 'road map' during the operation. With the 3D model the surgeon was more confident when opening the sellar wall and when evacuating the tumor from areas in contact with vital structures than when using only conventional 2D images.
PubMed ID
19086197 View in PubMed
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A 5-year longitudinal study of the relationship between the wish to be thinner, lifestyle behaviours and disturbed eating in 9-20-year old girls.

https://arctichealth.org/en/permalink/ahliterature99387
Source
Eur Eat Disord Rev. 2010 May;18(3):207-19
Publication Type
Article
Date
May-2010
Author
Josefin Westerberg-Jacobson
Birgitta Edlund
Ata Ghaderi
Author Affiliation
Department of Public Health, Uppsala University, BMC, Husargatan, Uppsala, Sweden. josefin.westerberg-jacobson@pubcare.uu.se
Source
Eur Eat Disord Rev. 2010 May;18(3):207-19
Date
May-2010
Language
English
Publication Type
Article
Keywords
Adolescent
Body Image
Body mass index
Child
Diet, Reducing - psychology
Eating Disorders - prevention & control - psychology
Female
Health Knowledge, Attitudes, Practice
Humans
Life Style
Prospective Studies
Risk factors
Sedentary lifestyle
Sweden
Young Adult
Abstract
The aim of this 5-year longitudinal study of 593 girls (9-20-year-old) was to examine whether the internalization of the thinness ideal in terms of 'a wish to be thinner' might be related to lifestyle factors and longitudinally increase the risk of disturbed eating over time. Results showed that a wish to be thinner was related to lifestyle factors, eating attitudes and body mass index (BMI) longitudinally. Girls who wished to be thinner dieted more often, thought that they would be more popular if they were thinner, skipped meals, were eating breakfast more often alone and had a higher BMI compared to the girls without such a wish. Girls who wished to be thinner were 4 times more likely to develop disturbed eating attitudes over a 5-year period. These findings point to the importance of helping adolescents to establish regular eating habits, to avoid unhealthy dieting practices and to prevent sedentary behaviours that might lead to overweight and or obesity in early childhood.
PubMed ID
20443204 View in PubMed
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The 6-Minute Walk Test as a Predictor of Summit Success on Denali.

https://arctichealth.org/en/permalink/ahliterature279175
Source
Wilderness Environ Med. 2016 Mar;27(1):19-24
Publication Type
Article
Date
Mar-2016
Author
Katherine M Shea
Eric R Ladd
Grant S Lipman
Patrick Bagley
Elizabeth A Pirrotta
Hurnan Vongsachang
N Ewen Wang
Paul S Auerbach
Source
Wilderness Environ Med. 2016 Mar;27(1):19-24
Date
Mar-2016
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Alaska
Female
Humans
Male
Middle Aged
Mountaineering - statistics & numerical data
Prospective Studies
Walk Test - methods
Young Adult
Abstract
To test whether the 6-minute walk test (6MWT), including postexercise vital sign measurements and distance walked, predicts summit success on Denali, AK.
This was a prospective observational study of healthy volunteers between the ages of 18 and 65 years who had been at 4267 m for less than 24 hours on Denali. Physiologic measurements were made after the 6MWT. Subjects then attempted to summit at their own pace and, at the time of descent, completed a Lake Louise Acute Mountain Sickness Questionnaire and reported maximum elevation reached.
One hundred twenty-one participants enrolled in the study. Data were collected on 111 subjects (92% response rate), of whom 60% summited. On univariate analysis, there was no association between any postexercise vital sign and summit success. Specifically, there was no significant difference in the mean postexercise peripheral oxygen saturation (Spo2) between summiters (75%) and nonsummiters (74%; 95% CI, -3 to 1; P = .37). The distance a subject walked in 6 minutes (6MWTD) was longer in summiters (617 m) compared with nonsummiters (560 m; 95% CI, 7.6 to 106; P = .02). However, this significance was not maintained on a multivariate analysis performed to control for age, sex, and guide status (P = .08), leading to the conclusion that 6MWTD was not a robust predictor of summit success.
This study did not show a correlation between postexercise oxygen saturation or 6MWTD and summit success on Denali.
PubMed ID
26712335 View in PubMed
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6-Thioguanine therapy in Crohn's disease--observational data in Swedish patients.

https://arctichealth.org/en/permalink/ahliterature91993
Source
Dig Liver Dis. 2009 Mar;41(3):194-200
Publication Type
Article
Date
Mar-2009
Author
Almer S H C
Hjortswang H.
Hindorf U.
Author Affiliation
Department of Clinical and Experimental Medicine, Division of Gastroenterology and Hepatology, Faculty of Health Sciences, Linköping University, Linköping, Sweden. sven.almer@lio.se
Source
Dig Liver Dis. 2009 Mar;41(3):194-200
Date
Mar-2009
Language
English
Publication Type
Article
Keywords
6-Mercaptopurine - adverse effects
Adult
Aged
Antimetabolites, Antineoplastic - therapeutic use
Azathioprine - adverse effects
Crohn Disease - drug therapy
Drug resistance
Female
Humans
Immunosuppressive Agents - adverse effects
Male
Middle Aged
Prospective Studies
Remission Induction
Severity of Illness Index
Sweden
Thioguanine - therapeutic use
Young Adult
Abstract
BACKGROUND AND AIMS: Adverse events (AE) leading to discontinuation or dose-reduction of thiopurine therapy (TP) occur in 9-28% of patients with inflammatory bowel disease. 6-Thioguanine (6-TG) has been proposed as an alternative treatment in patients intolerant for azathioprine (AZA), but some concerns have been raised about drug safety. METHODS: We evaluated in a prospective manner the tolerance and efficacy of 6-TG in 23 Crohn's disease (CD) patients (13 men, median age 41 (19-65) years) with prior intolerance (n=18) or resistance (n=5) to AZA and/or 6-mercaptopurine (6-MP). In addition, eight patients had tried mycophenolate mofetil. Seventeen patients (74%) had undergone intestinal resection, often several times. RESULTS: Patients were treated with a median daily dose of 40 mg 6-TG (range 20-60) for 259 (15-2272) days. Seven of 13 patients (54%) with active disease went into remission after 8 (4-26) weeks. Sixteen patients (70%) experienced AE that lead to discontinuation (n=10) after 85 (15-451) days or dose reduction (n=6) after 78 (10-853) days. Ten of 18 patients (56%) with prior TP-intolerance discontinued 6-TG treatment due to AE compared to none of five patients with TP-resistance (p=0.046). Of 13 patients that tolerated 6-TG, eight discontinued the drug due to therapeutic failure (n=5) or safety concerns (n=3). Eight patients (35%) continued treatment beyond 12 months. There was no significant difference in maximum thioguanine nucleotide levels between patients with AE leading to discontinuation/dose reduction and patients without AE, 652 (99-2488) vs. 551 (392-1574) pmol/8 x 10(8) RBC; p=0.80. CONCLUSIONS: In this cohort of CD patients with severe disease failing traditional thiopurine treatment, a small fraction (22%) had long-term benefit of 6-TG-treatment. 6-TG therapy seems to offer a limited therapeutic gain for patients intolerant to both AZA and 6-MP and other treatment options should be considered.
PubMed ID
18799369 View in PubMed
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A 7-year prospective study of sense of humor and mortality in an adult county population: the HUNT-2 study.

https://arctichealth.org/en/permalink/ahliterature140723
Source
Int J Psychiatry Med. 2010;40(2):125-46
Publication Type
Article
Date
2010
Author
Sven Svebak
Solfrid Romundstad
Jostein Holmen
Author Affiliation
The Norwegian University of Science and Technology, Trondheim, Norway. sven.svebak@ntnu.no
Source
Int J Psychiatry Med. 2010;40(2):125-46
Date
2010
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Cohort Studies
Female
Health Behavior
Health Status Indicators
Health Surveys
Humans
Kaplan-Meier Estimate
Life Style
Male
Middle Aged
Mortality
Norway
Proportional Hazards Models
Prospective Studies
Questionnaires
Wit and Humor as Topic
Young Adult
Abstract
To prospectively explore the significance of sense of humor for survival over 7 years in an adult county population.
Residents in the county of Nord-Trøndelag, Norway, aged 20 and older, were invited to take part in a public health survey during 1995-97 (HUNT-2), and 66,140 (71.2 %) participated. Sense of humor was estimated by responses to a cognitive (N = 53,546), social (N = 52,198), and affective (N = 53,132) item, respectively, taken from the Sense of Humor Questionnaire (SHQ). Sum scores were tested by Cox survival regression analyses applied to gender, age, and subjective health.
Hazard ratios were reduced with sense of humor (continuous scale: HR = 0.73; high versus low by median split: HR = 0.50) as contrasted with increase of HR with a number of classical risk factors (e.g., cardiovascular disease: HR = 6.28; diabetes: HR = 4.86; cancer: HR = 4.18; poor subjective health: HR = 2.89). Gender proved to be of trivial importance to the effect of sense of humor in survival. Subjective health correlated positively with sense of humor and therefore might have presented a spurious relation of survival with humor, but sense of humor proved to reduce HR both in individuals with poor and good subjective health. However, above age 65 the effect of sense of humor on survival became less evident.
Sense of humor appeared to increase the probability of survival into retirement, and this effect appeared independent of subjective health. Age under 65 mediated this effect, whereas it disappeared beyond this age.
PubMed ID
20848871 View in PubMed
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(18)F-fluorodeoxyglucose-positron emission tomography/computed tomography after one cycle of chemotherapy in patients with diffuse large B-cell lymphoma: results of a Nordic/US intergroup study.

https://arctichealth.org/en/permalink/ahliterature272653
Source
Leuk Lymphoma. 2015 Jul;56(7):2005-12
Publication Type
Article
Date
Jul-2015
Author
Karen Juul Mylam
Lale Kostakoglu
Martin Hutchings
Morton Coleman
Dominick Lamonica
Myron S Czuczman
Louis F Diehl
Anne L Nielsen
Paw Jensen
Annika Loft
Helle W Hendel
Victor Iyer
Sirpa Leppä
Sirkku Jyrkkiö
Harald Holte
Mikael Eriksson
Dorte Gillstrøm
Per B Hansen
Marko Seppänen
Karin Hjorthaug
Peter de Nully Brown
Lars M Pedersen
Source
Leuk Lymphoma. 2015 Jul;56(7):2005-12
Date
Jul-2015
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Denmark
Female
Finland
Fluorodeoxyglucose F18 - pharmacokinetics
Follow-Up Studies
Humans
Lymphoma, Large B-Cell, Diffuse - drug therapy - mortality - pathology
Male
Middle Aged
Multimodal Imaging
Neoplasm Staging
Norway
Positron-Emission Tomography - methods
Prognosis
Prospective Studies
Radiopharmaceuticals - pharmacokinetics
Survival Rate
Sweden
Tissue Distribution
Tomography, X-Ray Computed - methods
United States
Young Adult
Abstract
We evaluated the predictive value of interim positon emission tomography (I-PET) after one course of chemoimmunotherapy in patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL). One hundred and twelve patients with DLBCL were enrolled. All patients had PET/computed tomography (CT) scans performed after one course of chemotherapy (PET-1). I-PET scans were categorized according to International Harmonization Project criteria (IHP), Deauville 5-point scale (D 5PS) with scores 1-3 considered negative (D 5PS > 3) and D 5PS with scores 1-4 considered negative (D 5PS = 5). Ratios of tumor maximum standardized uptake value (SUVmax) to liver SUVmax were also analyzed. We found no difference in progression-free survival (PFS) between PET-negative and PET-positive patients according to IHP and D 5PS > 3. The 2-year PFS using D 5PS = 5 was 50.9% in the PET-positive group and 84.8% in the PET-negative group (p = 0.002). A tumor/liver SUVmax cut-off of 3.1 to distinguish D 5PS scores of 4 and 5 provided the best prognostic value. PET after one course of chemotherapy was not able to safely discriminate PET-positive and PET-negative patients in different prognostic groups.
PubMed ID
25330442 View in PubMed
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A 24-month evaluation of amalgam and resin-based composite restorations: Findings from The National Dental Practice-Based Research Network.

https://arctichealth.org/en/permalink/ahliterature113423
Source
J Am Dent Assoc. 2013 Jun;144(6):583-93
Publication Type
Article
Date
Jun-2013
Author
Michael S McCracken
Valeria V Gordan
Mark S Litaker
Ellen Funkhouser
Jeffrey L Fellows
Douglass G Shamp
Vibeke Qvist
Jeffrey S Meral
Gregg H Gilbert
Author Affiliation
Department of Clinical and Community Sciences, School of Dentistry, University of Alabama at Birmingham, AL, USA.
Source
J Am Dent Assoc. 2013 Jun;144(6):583-93
Date
Jun-2013
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Age Factors
Aged
Child
Child, Preschool
Cohort Studies
Community-Based Participatory Research
Composite Resins - standards
Dental Amalgam - standards
Dental Materials - standards
Dental Prosthesis Repair - statistics & numerical data
Dental Restoration Failure - statistics & numerical data
Dental Restoration, Permanent - classification - standards
Dentists - statistics & numerical data
Female
Follow-Up Studies
Forecasting
Humans
Male
Middle Aged
Prospective Studies
Risk factors
Scandinavia
Sex Factors
Surface Properties
United States
Workload
Young Adult
Abstract
Knowing which factors influence restoration longevity can help clinicians make sound treatment decisions. The authors analyzed data from The National Dental Practice-Based Research Network to identify predictors of early failures of amalgam and resin-based composite (RBC) restorations.
In this prospective cohort study, the authors gathered information from clinicians and offices participating in the network. Clinicians completed a baseline data collection form at the time of restoration placement and annually thereafter. Data collected included patient factors, practice factors and dentist factors, and the authors analyzed them by using mixed-model logistic regression.
A total of 226 practitioners followed up 6,218 direct restorations in 3,855 patients; 386 restorations failed (6.2 percent) during the mean (standard deviation) follow-up of 23.7 (8.8) months. The number of tooth surfaces restored at baseline helped predict subsequent restoration failure; restorations with four or more restored surfaces were more than four times more likely to fail. Restorative material was not associated significantly with longevity; neither was tooth type. Older patient age was associated highly with failure (P
Notes
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Comment In: J Am Dent Assoc. 2013 Nov;144(11):122024177393
PubMed ID
23729455 View in PubMed
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Abnormal electroencephalograms in patients with long QT syndrome.

https://arctichealth.org/en/permalink/ahliterature106966
Source
Heart Rhythm. 2013 Dec;10(12):1877-83
Publication Type
Article
Date
Dec-2013
Author
Kristina H Haugaa
Tommy Tveit Vestervik
Stein Andersson
Jan Peder Amlie
Ellen Jørum
Leif Gjerstad
Erik Taubøll
Author Affiliation
Department of Cardiology, Oslo University Hospital-Rikshospitalet, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address: kristina.haugaa@rr-research.no.
Source
Heart Rhythm. 2013 Dec;10(12):1877-83
Date
Dec-2013
Language
English
Publication Type
Article
Keywords
Adult
Brain - physiopathology
Electroencephalography
Epilepsy - epidemiology - etiology - physiopathology
Female
Follow-Up Studies
Humans
Incidence
Long QT Syndrome - complications - physiopathology
Male
Middle Aged
Norway - epidemiology
Prospective Studies
Survival Rate - trends
Time Factors
Young Adult
Abstract
The long QT syndrome (LQTS) is an inherited cardiac channelopathy associated with syncope and sudden cardiac death due to ventricular arrhythmias. It is most frequently caused by potassium channel mutations. Potassium channels are also expressed in brain tissue and play an important role in idiopathic epilepsies. Recent reports have indicated that related potassium channel mutations may coexpress as concomitant epilepsy and LQTS.
The purpose of this study was to explore cerebral activity by means of EEG recordings in individuals with LQTS related to potassium channel mutations.
Seventeen individuals with confirmed LQTS related to potassium channel mutations (11 LQT1 and 6 LQT2) were prospectively studied with 21-channel electroencephalography (EEG) LQTS -related symptoms, comorbidity, medication, and QTc (12-lead ECG) were recorded. Sixteen healthy individuals previously studied with EEG served as a control group. All EEGs were reviewed by two independent neurophysiologists.
EEG recordings were abnormal in 12 of 17 patients (71%) in the LQTS group, whereas abnormalities were present in only 2 of 16 healthy controls (13%; P
Notes
Comment In: Heart Rhythm. 2013 Dec;10(12):1884-524121000
PubMed ID
24080067 View in PubMed
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Abnormal optic disc and retinal vessels in children with surgically treated hydrocephalus.

https://arctichealth.org/en/permalink/ahliterature90653
Source
Br J Ophthalmol. 2009 Apr;93(4):526-30
Publication Type
Article
Date
Apr-2009
Author
Andersson S.
Hellström A.
Author Affiliation
Department of Ophthalmology, The Queen Silvia Children's Hospital, Sahlgrenska University Hospital/Ostra, 416 85 Göteborg, Sweden. susann.andersson@oft.gu.se
Source
Br J Ophthalmol. 2009 Apr;93(4):526-30
Date
Apr-2009
Language
English
Publication Type
Article
Keywords
Adolescent
Child
Child, Preschool
Female
Fundus Oculi
Gestational Age
Humans
Hydrocephalus - complications - epidemiology - pathology - surgery
Image Processing, Computer-Assisted - methods
Infant, Newborn
Male
Ophthalmoscopy
Optic Atrophy - epidemiology - etiology - pathology
Prospective Studies
Retinal Vessels - pathology
Sweden - epidemiology
Young Adult
Abstract
AIMS: To investigate the morphology of the optic disc and retinal vessels in children with surgically treated hydrocephalus. METHODS: A prospective, population-based study was performed in 69 children (median age 9.6 years) with early surgically treated hydrocephalus. All children were examined by ophthalmoscopy. Additionally, optic disc and retinal vessel morphology was evaluated in 55 children by digital image analysis of ocular fundus photographs. RESULTS: Optic atrophy was found in 10 of 69 children (14%). In comparison with a reference group, the median optic-disc area was significantly smaller (p = 0.013) in the children with hydrocephalus. There was no corresponding difference in cup area, so the rim area was significantly smaller in the hydrocephalic children (p = 0.002). Children with hydrocephalus had an abnormal retinal vascular pattern, with significantly straighter retinal arteries and fewer central vessel branching points compared with controls (p
PubMed ID
19106149 View in PubMed
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1513 records – page 1 of 152.