Skip header and navigation

Refine By

55 records – page 1 of 6.

25-Hydroxyvitamin D in Canadian adults: biological, environmental, and behavioral correlates.

https://arctichealth.org/en/permalink/ahliterature141385
Source
Osteoporos Int. 2011 May;22(5):1389-99
Publication Type
Article
Date
May-2011
Author
L S Greene-Finestone
C. Berger
M. de Groh
D A Hanley
N. Hidiroglou
K. Sarafin
S. Poliquin
J. Krieger
J B Richards
D. Goltzman
Author Affiliation
Public Health Agency of Canada, Ottawa, Ontario, Canada. linda.greene-finestone@phac-aspc.gc.ca
Source
Osteoporos Int. 2011 May;22(5):1389-99
Date
May-2011
Language
English
Publication Type
Article
Keywords
Adult
Age Distribution
Aged
Body mass index
Canada - epidemiology
Cross-Sectional Studies
Diet - statistics & numerical data
Dietary Supplements
Female
Humans
Male
Middle Aged
Obesity - complications - epidemiology
Seasons
Sex Distribution
Skin Pigmentation - physiology
Sunlight
Vitamin D - administration & dosage - analogs & derivatives - blood
Vitamin D Deficiency - blood - epidemiology - etiology
Abstract
We assessed vitamin D status and its correlates in the population-based Canadian Multicentre Osteoporosis Study (CaMos). Results showed that serum 25-hydroxyvitamin D levels
PubMed ID
20730415 View in PubMed
Less detail

An increase in serum 25-hydroxyvitamin D concentrations preceded a plateau in type 1 diabetes incidence in Finnish children.

https://arctichealth.org/en/permalink/ahliterature259846
Source
J Clin Endocrinol Metab. 2014 Nov;99(11):E2353-6
Publication Type
Article
Date
Nov-2014
Author
Marjaana Mäkinen
Ville Simell
Juha Mykkänen
Jorma Ilonen
Riitta Veijola
Heikki Hyöty
Mikael Knip
Olli Simell
Jorma Toppari
Robert Hermann
Source
J Clin Endocrinol Metab. 2014 Nov;99(11):E2353-6
Date
Nov-2014
Language
English
Publication Type
Article
Keywords
Child
Child, Preschool
Diabetes Mellitus, Type 1 - blood - epidemiology
Female
Finland - epidemiology
Food, Fortified
Humans
Incidence
Infant
Male
Vitamin D - administration & dosage - analogs & derivatives - blood
Vitamin D Deficiency - blood - epidemiology
Abstract
In Finland the world-record for the highest incidence of type 1 diabetes has risen steeply over the past decades. However, after 2006 the incidence rate has plateaued. We showed earlier, that despite the strong genetic disease component, environmental factors are driving the increasing disease incidence.
Since vitamin D intake has increased considerably in the country since 2003, we analyzed how serum 25-hydroxyvitamin D (25[OH]D) concentration changed over time in healthy children, and the timely relation of these changes to disease incidence.
The birth cohort of the Finnish Type 1 Diabetes Prediction and Prevention project was used to explore longitudinal changes in serum 25-hydroxyvitamin concentrations. The sampling period was limited to children born from 1994 to 2004, with serum samples collected during 1998-2006 in the Turku area, Southwest Finland (60 ?N).
25(OH)D concentrations were measured every 3-6 months from birth, ages ranging from 0.3 to 12.2 years (387 subjects, 5334 measurements).
Serum 25(OH)D concentrations were markedly lower before 2003 than after (69.3 ? 1.0 nmol/L vs 84.9 ? 1.3 nmol/L, respectively, P
PubMed ID
25062454 View in PubMed
Less detail

Association between serum 25-hydroxyvitamin D concentration and symptoms of respiratory tract infection in a Norwegian population: the Tromsø Study.

https://arctichealth.org/en/permalink/ahliterature257672
Source
Public Health Nutr. 2014 Apr;17(4):780-6
Publication Type
Article
Date
Apr-2014
Author
Steinar Robertsen
Guri Grimnes
Hasse Melbye
Author Affiliation
1 General Practice Research Unit, Department of Community Medicine, MH-building, Faculty of Health Science, University of Tromsø, 9037 Tromsø, Norway.
Source
Public Health Nutr. 2014 Apr;17(4):780-6
Date
Apr-2014
Language
English
Publication Type
Article
Keywords
Aged
Dietary Supplements
Female
Humans
Incidence
Male
Middle Aged
Norway - epidemiology
Prevalence
Respiratory Tract Infections - blood - epidemiology - prevention & control
Risk factors
Vitamin D - administration & dosage - analogs & derivatives - blood
Vitamin D Deficiency - blood - epidemiology
Abstract
Previous studies have suggested anti-infection effects of vitamin D, although the associations reported between vitamin D (serum 25-hydroxyvitamin D (25(OH)D) concentration) and respiratory tract infection (RTI) are conflicting. The main aim of the present study was to explore this association in a Norwegian population.
We examined the association between serum 25(OH)D and recent RTI symptoms in 6350 middle-aged and elderly participants in the Tromsø Study 6. The main outcome measurement was self-reported RTI symptoms in the previous week.
Tromsø, Norway, 69 °N.
Six thousand three hundred and fifty middle-aged and elderly residents of Tromsø.
Of the 6350 included, 791 (12.5%) reported RTI symptoms in the previous week. We classified serum 25(OH)D concentrations into quartiles and adjusted the data for current smoking habit and month of attendance. The prevalence of RTI symptoms did not increase with decreasing serum 25(OH)D level, was highest in quartile 3 (15.0%) followed by quartile 4 (12.4%), and was lowest in quartiles 1 and 2 (11.1% and 11.4%). There was no trend for increasing duration of illness with decreasing serum 25(OH)D. The prevalence of RTI symptoms was not significantly associated with the intake of fish, n-3 capsules or vitamin and/or mineral supplements, or sun exposure. Only use of cod-liver oil or fish oil capsules daily or sometimes was significantly associated with fewer RTI symptoms during the preceding 7 d (P = 0.04).
Low serum 25(OH)D was not associated with increased prevalence of recent RTI symptoms. Our findings do not support the idea that vitamin D supplementation can reduce the incidence of RTI in Norway.
PubMed ID
23659381 View in PubMed
Less detail

Association of vitamin D related information from a telephone interview with 25-hydroxyvitamin D.

https://arctichealth.org/en/permalink/ahliterature159312
Source
Cancer Epidemiol Biomarkers Prev. 2008 Jan;17(1):232-8
Publication Type
Article
Date
Jan-2008
Author
Harleen Sahota
Heidi Barnett
Maia Lesosky
Janet M Raboud
Reinhold Vieth
Julia A Knight
Author Affiliation
Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 60 Murray Street, Toronto, Ontario, Canada.
Source
Cancer Epidemiol Biomarkers Prev. 2008 Jan;17(1):232-8
Date
Jan-2008
Language
English
Publication Type
Article
Keywords
Adult
Aged
Body mass index
Breast Neoplasms - epidemiology - prevention & control
Case-Control Studies
Female
Health Surveys
Humans
Interviews as Topic
Middle Aged
Ontario - epidemiology
Questionnaires
Risk factors
Seasons
Sunlight
Telephone
Ultraviolet Rays
Vitamin D - administration & dosage - analogs & derivatives - blood
Abstract
Vitamin D may be associated with reduced risks of several types of cancer, including colon, prostate, and breast. We examined the relationship between vitamin D-related questions administered in a telephone interview and serum 25-hydroxyvitamin D [25(OH)D]. Three hundred and eight eligible women were randomly selected from controls in a breast cancer case-control study. Questions pertaining to sun exposure and dietary sources of vitamin D over the previous 4 weeks were asked in both summer and winter. We assessed the association between questionnaire-derived items and 25(OH)D using multiple linear regression. There were 217 participating women, 203 in summer and 213 in winter. Models were adjusted for age, body mass index, and skin color. Number of days when more than 0.5 hour was spent outdoors per week ("7" versus "10" beta = 18.94, ">5-10" beta = 9.16, and "1-5" beta = 7.90 versus "10" beta = 14.54, ">5-10" beta = 11.54, and "1-5" beta = 2.15 versus "
PubMed ID
18199729 View in PubMed
Less detail

Associations between serum 25-hydroxyvitamin d and periodontal pocketing and gingival bleeding: results of a study in a non-smoking population in Finland.

https://arctichealth.org/en/permalink/ahliterature277832
Source
J Periodontol. 2015 Jun;86(6):755-65
Publication Type
Article
Date
Jun-2015
Author
Georgios N Antonoglou
Anna Liisa Suominen
Matti Knuuttila
Pekka Ylöstalo
Meeri Ojala
Satu Männistö
Jukka Marniemi
Annamari Lundqvist
Tellervo Tervonen
Source
J Periodontol. 2015 Jun;86(6):755-65
Date
Jun-2015
Language
English
Publication Type
Article
Keywords
Adult
Cross-Sectional Studies
DMF Index
Dental Plaque Index
Dietary Supplements
Educational Status
Energy intake
Female
Finland
Food Habits
Gingival Hemorrhage - blood
Humans
Male
Middle Aged
Oral Hygiene
Periodontal Pocket - blood
Toothbrushing - statistics & numerical data
Vitamin D - administration & dosage - analogs & derivatives - blood
Vitamins - administration & dosage - blood
Abstract
Apart from the effects of vitamin D on bone metabolism, it is also known for its immunomodulatory properties. However, so far, it is not clear whether serum 25-hydroxyvitamin D [25(OH)D] exerts any beneficial effect on the periodontium. The aim of the present study is to investigate whether the serum level of 25(OH)D is related to periodontal condition, measured by means of pocketing and gingival bleeding.
This cross-sectional study is based on a non-smoking subpopulation without diabetes of the Finnish Health 2000 Survey (N = 1,262). Periodontal condition was measured as the number of teeth with deep (=4 mm) periodontal pockets and the number of bleeding sextants per individual. Serum 25(OH)D level was determined by means of a standard laboratory measurement. Prevalence rate ratios and 95% confidence intervals were estimated using Poisson regression models.
There were practically no associations between serum 25(OH)D level and teeth with deep (=4 mm) periodontal pockets or bleeding sextants. A somewhat lower proportion of teeth with deep periodontal pockets was found in higher serum 25(OH)D quintiles among individuals with a good oral hygiene level.
Serum 25(OH)D did not seem to be related to periodontal condition, measured as periodontal pocketing and gingival bleeding in this low-risk, low-25(OH)D status population.
PubMed ID
25762358 View in PubMed
Less detail

Associations between vitamin D status in infants and blood lipids, body mass index and waist circumference.

https://arctichealth.org/en/permalink/ahliterature136053
Source
Acta Paediatr. 2011 Sep;100(9):1244-8
Publication Type
Article
Date
Sep-2011
Author
K. Arnberg
M. Østergård
A L Madsen
H. Krarup
K F Michaelsen
C. Mølgaard
Author Affiliation
Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark. kaar@life.ku.dk
Source
Acta Paediatr. 2011 Sep;100(9):1244-8
Date
Sep-2011
Language
English
Publication Type
Article
Keywords
Blood Glucose - metabolism
Body mass index
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Cross-Sectional Studies
Denmark
Dietary Supplements
Female
Humans
Infant
Insulin - blood
Lipids - blood
Luminescent Measurements
Male
Nutritional Status
Reference Values
Statistics as Topic
Statistics, nonparametric
Vitamin D - administration & dosage - analogs & derivatives - blood
Waist Circumference
Abstract
To study the relationships between 25-hydroxyvitamin D status and blood lipids, insulin, glucose, body mass index and waist circumference in infants.
In a cross-sectional study, 255 infants aged 9 months with a blood sample for 25-hydroxyvitamin D were examined. Plasma 25-hydroxyvitamin D concentrations were analysed by chemiluminescent immunoassay. Associations between plasma 25-hydroxyvitamin D and high-density lipoprotein (HDL), low-density lipoprotein, total cholesterol, triglycerides, insulin, glucose, body mass index and waist circumference were analysed.
Mean plasma 25-hydroxyvitamin D was 77.2 ± 22.7 nM. At the time of examination, 97% received vitamin D supplementation. 25-Hydroxyvitamin D was negatively associated with HDL (p = 0.003), cholesterol (p = 0.002) and triglycerides (p = 0.010) in multivariate analysis controlled for gender, season, body mass index, length, birth weight and breastfeeding. There were no associations between 25-hydroxyvitamin D and glucose or insulin (all p > 0.05). 25-hydroxyvitamin D was negatively associated with body mass index (p = 0.005) and waist circumference (p = 0.002) controlled for gender, season, breastfeeding, birth weight and length.
Vitamin D status is negatively associated with blood lipids, body mass index and waist circumference in infants where nearly all received vitamin D supplements. Whether this has long-term health effects remains to be elucidated.
PubMed ID
21418102 View in PubMed
Less detail
Source
J Prev Med Public Health. 2017 Jul; 50(4):278-281
Publication Type
Journal Article
Date
Jul-2017
Author
Dimitrios T Papadimitriou
Author Affiliation
Third Department of Pediatrics, Division of Pediatric Endocrinology, Attikon University Hospital, University of Athens School of Medicine, Athens, Greece.
Source
J Prev Med Public Health. 2017 Jul; 50(4):278-281
Date
Jul-2017
Language
English
Publication Type
Journal Article
Keywords
Adolescent
Autoimmune Diseases - mortality - prevention & control
Cause of Death
Child
Child, Preschool
Dietary Supplements - standards
Finland - epidemiology
Guidelines as Topic
Humans
Immune System - metabolism
Infant
Medication Errors
Metabolic Syndrome - mortality - prevention & control
Public Health
Vitamin D - administration & dosage - analogs & derivatives - blood - standards
Vitamin D Deficiency - epidemiology - prevention & control
Young Adult
Abstract
Since 2006, type 1 diabetes in Finland has plateaued and then decreased after the authorities' decision to fortify dietary milk products with cholecalciferol. The role of vitamin D in innate and adaptive immunity is critical. A statistical error in the estimation of the recommended dietary allowance (RDA) for vitamin D was recently discovered; in a correct analysis of the data used by the Institute of Medicine, it was found that 8895 IU/d was needed for 97.5% of individuals to achieve values =50 nmol/L. Another study confirmed that 6201 IU/d was needed to achieve 75 nmol/L and 9122 IU/d was needed to reach 100 nmol/L. The largest meta-analysis ever conducted of studies published between 1966 and 2013 showed that 25-hydroxyvitamin D levels 1 year of age, and around 8000 IU for young adults and thereafter. Actions are urgently needed to protect the global population from vitamin D deficiency.
Notes
Cites: J Diabetes. 2013 Sep;5(3):344-8 PMID 23302101
Cites: Nutrients. 2014 Oct 20;6(10):4472-5 PMID 25333201
Cites: Diabetes. 2002 Jul;51(7):2119-25 PMID 12086941
Cites: Metabolism. 2014 Sep;63(9):1115-24 PMID 25044176
Cites: J Steroid Biochem Mol Biol. 2014 Oct;144 Pt A:172-9 PMID 24184871
Cites: Nutrients. 2015 Mar 10;7(3):1688-90 PMID 25763527
Cites: Am J Public Health. 2014 Aug;104(8):e43-50 PMID 24922127
Cites: Lancet. 2001 Nov 3;358(9292):1500-3 PMID 11705562
Cites: J Clin Endocrinol Metab. 2014 Nov;99(11):E2353-6 PMID 25062454
Cites: Diabetes Care. 1999 Jul;22(7):1066-70 PMID 10388969
PubMed ID
28768407 View in PubMed
Less detail

[Breast density: a biomarker to better understand and prevent breast cancer].

https://arctichealth.org/en/permalink/ahliterature167463
Source
Bull Cancer. 2006 Sep;93(9):847-55
Publication Type
Article
Date
Sep-2006
Author
Jacques Brisson
Sylvie Bérubé
Caroline Diorio
Author Affiliation
Unité de recherche en santé des populations (URESP), Centre hospitalier affilié universitaire de Québec, 1050 chemin Sainte-Foy, Québec, Qc, Canada G1S 4L8. jacques.brisson@uresp.ulaval.ca
Source
Bull Cancer. 2006 Sep;93(9):847-55
Date
Sep-2006
Language
French
Publication Type
Article
Keywords
25-Hydroxyvitamin D 2 - blood
Antineoplastic Agents, Hormonal - therapeutic use
Breast - drug effects - pathology
Breast Neoplasms - blood - pathology - prevention & control
Calcium, Dietary - administration & dosage - blood
Female
Humans
Mammography
Polymorphism, Genetic
Premenopause
Quebec
Receptors, Calcitriol - genetics
Risk assessment
Somatomedins - genetics - metabolism
Tamoxifen - therapeutic use
Tumor Markers, Biological - blood
Vitamin D - administration & dosage - analogs & derivatives - blood
Abstract
In Quebec, cancer is the principal cause of mortality. This epidemiologic research program includes two components. The first component takes place at the "Institut national de santé publique du Québec" and involves surveillance and evaluation of practices in oncology with the aim of providing the Quebec Ministry of Health with some of the evidence needed to determine its policies in cancer control. The second component takes place at the "Unité de recherche en santé des populations (URESP)" of Laval University and is devoted to studying the etiology and prevention of breast cancer. This paper focuses on this second research component which uses mammographic breast density as an intermediate biomarker to study the causes of breast cancer and strategies to prevent it. Breast cancer risk is much higher among women with very dense breasts than among those with little or no breast density. Recently, we were among the first to show that women with high vitamin D or calcium intakes have less breast density than those with low intakes, especially among premenopausal women. Furthermore, we have confirmed that breast density was increased among premenopausal women with high levels of IGF-I and low levels of IGFBP3 which is consistent with the observed effect of these molecules on breast cancer risk. Studies are now being conducted to assess whether breast density varies according to blood levels of vitamin D and of additional growth factors, as well as to genetic polymorphisms involved in the pathways of vitamin D, calcium and growth factors. The increase in vitamin D and calcium intakes may prove to be a safe and inexpensive approach to breast cancer prevention; this possibility should be carefully examined as quickly as possible.
PubMed ID
16980227 View in PubMed
Less detail

Canadian Aboriginal women have a higher prevalence of vitamin D deficiency than non-Aboriginal women despite similar dietary vitamin D intakes.

https://arctichealth.org/en/permalink/ahliterature165548
Source
J Nutr. 2007 Feb;137(2):461-5
Publication Type
Article
Date
Feb-2007
Author
Hope A Weiler
William D Leslie
John Krahn
Pauline Wood Steiman
Colleen J Metge
Author Affiliation
Human Nutritional Sciences, Faculty of Medicine, University of Manitoba, Winnipeg, R3T 2N2 MB, Canada. hope.weiler@mcgill.ca
Source
J Nutr. 2007 Feb;137(2):461-5
Date
Feb-2007
Language
English
Publication Type
Article
Keywords
Adult
Aged
Calcium, Dietary - administration & dosage
Canada - epidemiology - ethnology
Diet - statistics & numerical data
Diet Surveys
Female
Humans
Indians, North American - statistics & numerical data
Middle Aged
Prevalence
Vitamin D - administration & dosage - analogs & derivatives - blood
Vitamin D Deficiency - epidemiology - ethnology
Abstract
Canadian Aboriginal women have high rates of bone fractures, which is possibly due to low dietary intake of minerals or vitamin D. This study was undertaken to estimate dietary intake of calcium and vitamin D by designing a culturally appropriate dietary survey instrument and to determine whether disparities exist between Aboriginal and white women. After validation of a FFQ, 183 urban-dwelling and 26 rural-dwelling Aboriginal women and 146 urban white women completed the validated FFQ and had serum 25-hydroxyvitamin D [25(OH)D] measured. Urban Aboriginal women had lower (P=0.0004) intakes of total dietary calcium than urban white women; there was no difference in rural Aboriginal women. Only a minority of all women met the adequate intake (AI) for calcium intake. Ethnicity did not affect total vitamin D intake; however, rural Aboriginal women consumed all of their dietary vitamin D from food sources, which was more (P
PubMed ID
17237327 View in PubMed
Less detail

Commonly recommended daily intake of vitamin D is not sufficient if sunlight exposure is limited.

https://arctichealth.org/en/permalink/ahliterature61816
Source
J Intern Med. 2000 Feb;247(2):260-8
Publication Type
Article
Date
Feb-2000
Author
H. Glerup
K. Mikkelsen
L. Poulsen
E. Hass
S. Overbeck
J. Thomsen
P. Charles
E F Eriksen
Author Affiliation
Department of Endocrinology, Aarhus Amtssygehus, University Hospital of Aarhus, Aarhus, Denmark. h.glerup@dadlnet.dk
Source
J Intern Med. 2000 Feb;247(2):260-8
Date
Feb-2000
Language
English
Publication Type
Article
Keywords
Adult
Alkaline Phosphatase - blood
Arabs
Calcium - blood - urine
Case-Control Studies
Clothing - adverse effects
Creatinine - blood
Cross-Sectional Studies
Denmark - ethnology
Female
Food Habits
Humans
Hydroxyproline - urine
Hyperparathyroidism, Secondary - blood - diagnosis
Magnesium - blood
Nutrition Policy
Parathyroid Hormone - blood
Phosphates - blood
Sunlight
Ultraviolet Rays
Vitamin D - administration & dosage - analogs & derivatives - blood
Vitamin D Deficiency - blood - etiology
Abstract
OBJECTIVES: Sunlight exposure of the skin is known to be the most important source of vitamin D. The aims of this study were: (i) to estimate vitamin D status amongst sunlight-deprived individuals (veiled Arab women, veiled ethnic Danish Moslem women and Danish controls); and (ii) through food intake analysis to estimate the oral intake of vitamin D necessary to keep a normal vitamin D status in sunlight-deprived individuals. DESIGN: Cross-sectional study amongst randomly selected Moslem women of Arab origin living in Denmark. Age-matched Danish women were included as controls. To control for racial differences, a group of veiled ethnic Danish Moslem women (all Caucasians) was included. SETTING: Primary Health Care Centre, City Vest and Department of Endocrinology and Metabolism C, University Hospital of Aarhus, Aarhus Amtssygehus, Aarhus, Denmark. SUBJECTS: Sixty-nine Arab women (60 veiled, nine non-veiled) and 44 age-matched Danish controls were randomly selected amongst patients contacting the primary health care centre for reasons other than vitamin D deficiency. Ten ethnic Danish Moslem women were included through a direct contact with their community. MAIN OUTCOME MEASURES: Serum levels of 25-hydroxyvitamin D were used as estimates of vitamin D status. Intact parathyroid hormone (PTH) was used to control for secondary hyperparathyroidism. Alkaline phosphatase and bone-specific alkaline phosphatase were used as markers for osteomalacic bone involvement. Oral intake of vitamin D and calcium were estimated through a historical food intake interview performed by a trained clinical dietician. RESULTS: Veiled Arab women displayed extremely low values of 25-hydroxyvitamin D: 7.1 +/- 1.1 nmol L-1, compared with 17.5 +/- 2. 3 (P
PubMed ID
10692090 View in PubMed
Less detail

55 records – page 1 of 6.