This study presents the adverse affects of acupuncture as recorded in the Medline database for the years 1981-92. Pneumothorax is the most common mechanical organ injury caused, while hepatitis dominates the infections. Neither pneumothorax nor hepatitis is reported from any Nordic country. Most of the adverse effects of acupuncture seem to be associated with insufficient basic medical knowledge, a low standard of hygiene and inadequate education in acupuncture. The study confirms adverse effects of acupuncture in certain circumstances. Serious adverse effects are few, and acupuncture can be considered as a fairly harmless form of treatment.
Comment In: Tidsskr Nor Laegeforen. 1994 May 20;114(13):15618079254
Comment In: Tidsskr Nor Laegeforen. 1994 May 30;114(14):16478079272
Comment In: Tidsskr Nor Laegeforen. 1996 Mar 30;116(9):11538658487
Unstable hemoglobin (Hb) variants are the result of sequence variants in the globin genes causing precipitation of Hb molecules in red blood cells (RBCs). Intracellular inclusions derived from the unstable Hb reduce the life-span of the red cells and may cause hemolytic anemia. Here we describe a patient with a history of hemolytic anemia and low oxygen saturation. She was found to be carrier of a novel unstable Hb variant, Hb Oslo [ß42(CD1)Phe?Ile (TTT>ATT), HBB: c.127T>A] located in the heme pocket of the ß-globin chain. Three-dimensional modeling suggested that isoleucine at position 42 creates weaker interactions with distal histidine and with the heme itself, which may lead to altered stability and decreased oxygen affinity. At steady state, the patient was in good clinical condition with a Hb concentration of 8.0-9.0?g/dL. During virus infections, the Hb concentration fell and on six occasions during 4 years, the patient needed a blood transfusion.
Because few reports have addressed infections late (=1 year) after liver transplantation (LT), we evaluated the incidence, risk factors and pathogens involved. Infection data were from the Finnish LT registry, with starting date, type and relevant pathogens for 501 Finnish adult LT patients surviving =1 year post-transplant. Follow-up end points were end of study, death or retransplantation. Logistic regression to assess risk factors was adjusted for age, gender and follow-up time. With 3923 person-years of follow-up, overall infection incidence was 66/1000 person-years; 155 (31%) suffered 259 infections, and two-thirds experienced only one infection. Cholangitis (20%), pneumonia (19%) and sepsis (14%) were most common. The most frequent bacteria were Enterococcus spp. and Escherichia coli, and the most frequent viruses cytomegalovirus and varicella zoster virus. Fungal infections were rare (n = 7). With 13 fatal infections, 17% of all late deaths involved infection. Primary sclerosing cholangitis (PSC) and Roux-en-Y-type biliary anastomosis were associated with cholangitis; 18% of PSC patients suffered late cholangitis. Late acute rejection was associated with sepsis. Age, gender or cytomegalovirus did not significantly influence late infections. In conclusion, although infection risk under maintenance immunosuppression therapy is relatively low, particular vigilance regarding cholangitis, pneumonia and sepsis seems appropriate.
BACKGROUND: Infections cause significant morbidity in children with acute lymphoblastic leukemia (ALL). The incidence of viral infections commonly occurring in children with ALL receiving chemotherapy was compared with viral infections in control children and the spread of infections in families was traced. METHODS: Fifteen families of children with ALL receiving chemotherapy (62 members) and 26 matched control families (106 members) were monitored for a total of 36,197 and 36,583 days, respectively, from November/ 1987 to December/1989 for the occurrence of infections. RESULTS: The children with ALL had more infections than their control counterparts (P
The drinking water was tested for viruses in the industrial towns of Eastern Siberia. The findings suggest that extremely poor provision with good quality drinking water is seen in the town of Ust-Ilimsk where there were high levels of pathogenic viruses in the water. The high contamination of drinking water with hepatitis A virus and rotavirus is a cause of higher incidence of intestinal viral infections in the areas under study.