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Age and gender differences in left ventricular function among patients with stable angina and a matched control group. A report from the Angina Prognosis Study in Stockholm.

https://arctichealth.org/en/permalink/ahliterature11210
Source
Cardiology. 1996 Jul-Aug;87(4):287-93
Publication Type
Article
Author
S V Eriksson
I. Björkander
C. Held
P. Hjemdahl
L. Forslund
N. Rehnqvist
Author Affiliation
Department of Medicine, Danderyd Hospital, Karolinska Institute, Sweden.
Source
Cardiology. 1996 Jul-Aug;87(4):287-93
Language
English
Publication Type
Article
Keywords
Adrenergic beta-Antagonists - therapeutic use
Age Factors
Aged
Angina Pectoris - drug therapy - physiopathology - ultrasonography
Blood Pressure - physiology
Calcium Channel Blockers - therapeutic use
Comparative Study
Double-Blind Method
Echocardiography, Doppler
Electrocardiography
Female
Heart Rate - physiology
Humans
Male
Metoprolol - therapeutic use
Middle Aged
Multivariate Analysis
Research Support, Non-U.S. Gov't
Sex Factors
Sweden
Ventricular Dysfunction, Left - drug therapy - physiopathology - ultrasonography
Ventricular Function, Left - physiology
Verapamil - therapeutic use
Abstract
To assess left ventricular systolic and diastolic function, M-mode (n = 675) and transmitral Doppler echocardiography (n = 358) were performed in patients with stable angina pectoris and compared with 50 matched healthy controls. Left ventricular fractional shortening (FS) was significantly lower in male than in female patients (32 +/- 7 vs. 35 +/- 7%, p
PubMed ID
8793161 View in PubMed
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Age and gender specific normal values of left ventricular mass, volume and function for gradient echo magnetic resonance imaging: a cross sectional study.

https://arctichealth.org/en/permalink/ahliterature90338
Source
BMC Med Imaging. 2009;9:2
Publication Type
Article
Date
2009
Author
Cain Peter A
Ahl Ragnhild
Hedstrom Erik
Ugander Martin
Allansdotter-Johnsson Ase
Friberg Peter
Arheden Hakan
Author Affiliation
Department of Clinical Physiology, Lund University Hospital, SE-22185, Lund, Sweden. peteracain@gmail.com
Source
BMC Med Imaging. 2009;9:2
Date
2009
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Child
Cross-Sectional Studies
Echo-Planar Imaging - statistics & numerical data
Female
Heart Ventricles - anatomy & histology
Humans
Male
Middle Aged
Organ Size - physiology
Reference Values
Reproducibility of Results
Sensitivity and specificity
Sex Distribution
Stroke Volume - physiology
Sweden - epidemiology
Ventricular Function, Left - physiology
Young Adult
Abstract
BACKGROUND: Knowledge about age-specific normal values for left ventricular mass (LVM), end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV) and ejection fraction (EF) by cardiac magnetic resonance imaging (CMR) is of importance to differentiate between health and disease and to assess the severity of disease. The aims of the study were to determine age and gender specific normal reference values and to explore the normal physiological variation of these parameters from adolescence to late adulthood, in a cross sectional study. METHODS: Gradient echo CMR was performed at 1.5 T in 96 healthy volunteers (11-81 years, 50 male). Gender-specific analysis of parameters was undertaken in both absolute values and adjusted for body surface area (BSA). RESULTS: Age and gender specific normal ranges for LV volumes, mass and function are presented from the second through the eighth decade of life. LVM, ESV and EDV rose during adolescence and declined in adulthood. SV and EF decreased with age. Compared to adult females, adult males had higher BSA-adjusted values of EDV (p = 0.006) and ESV (p
PubMed ID
19159437 View in PubMed
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Age dependency in the timing of mitral annular motion in relation to ventricular filling in healthy subjects: Umea General Population Heart Study.

https://arctichealth.org/en/permalink/ahliterature157109
Source
Eur J Echocardiogr. 2008 Jul;9(4):522-9
Publication Type
Article
Date
Jul-2008
Author
F. Bukachi
A. Waldenström
S. Mörner
P. Lindqvist
M Y Henein
E. Kazzam
Author Affiliation
Department of Medical Physiology, College of Health Sciences, Nairobi, Kenya.
Source
Eur J Echocardiogr. 2008 Jul;9(4):522-9
Date
Jul-2008
Language
English
Publication Type
Article
Keywords
Adult
Age Factors
Aged
Aged, 80 and over
Aging
Diastole - physiology
Echocardiography, Doppler
Female
Humans
Male
Middle Aged
Mitral Valve - physiology - ultrastructure
Time Factors
Ventricular Function
Ventricular Function, Left - physiology
Abstract
Peak left ventricular (LV) relaxation normally precedes peak filling (E), which supports the hypothesis that LV suction contributes to early-diastolic filling. The significance of similar temporal discordance in late diastole has previously not been studied. We describe the time relationships between mitral annular motion and LV filling in early and late diastole and examine the effect of normal ageing on these time intervals.
A total of 128 healthy subjects aged 25-88 years were studied. Transmitral and pulmonary venous flow reversals (Ar) were recorded by Doppler echocardiography. Mitral annular diastolic displacement-early (E(m)) and late (A(m))-were recorded by Doppler tissue imaging. With reference to electrocardiographic R and P-waves, the following measurements were made: R to peak E-wave (R-E) and E(m) (R-E(m)); onset P to peak A-wave (P-pA), A(m) (P-pA(m)), and Ar (P-pAr). The differences between [(R-E) and (R-E(m))] for early-diastolic temporal discordance (EDTD) and [(P-A) and (P-A(m))] for late-diastolic temporal discordance (LDTD) were calculated. Isovolumic relaxation time (IVRT) was also measured. Early-diastolic temporal discordance was approximately 26 ms in all age groups. Late-diastolic temporal discordance, however, was inversely related to age (r = -0.35, P
PubMed ID
18490308 View in PubMed
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Are left ventricular mass, geometry and function related to vascular changes and/or insulin resistance in long-standing hypertension? ICARUS: a LIFE substudy.

https://arctichealth.org/en/permalink/ahliterature53541
Source
J Hum Hypertens. 2003 May;17(5):305-11
Publication Type
Article
Date
May-2003
Author
M H Olsen
E. Hjerkinn
K. Wachtell
A. Høieggen
J N Bella
S D Nesbitt
E. Fossum
S E Kjeldsen
S. Julius
H. Ibsen
Author Affiliation
Department of Clinical Physiology and Nuclear Medicine, Glostrup University Hospital, Copenhagen, Denmark. mho@dadlnet.dk
Source
J Hum Hypertens. 2003 May;17(5):305-11
Date
May-2003
Language
English
Publication Type
Article
Keywords
Aged
Blood Flow Velocity - physiology
Blood Glucose - metabolism
Blood Pressure - physiology
Carotid Artery, Common - physiopathology
Comparative Study
Denmark
Diastole - physiology
Echocardiography
Female
Heart Ventricles - metabolism - physiopathology - ultrasonography
Humans
Hypertension - metabolism - physiopathology
Hypertrophy, Left Ventricular - metabolism - physiopathology
Insulin - blood
Insulin Resistance - physiology
Male
Middle Aged
Norway
Research Support, Non-U.S. Gov't
Sex Factors
Statistics
Stroke Volume - physiology
Systole - physiology
United States
Vascular Resistance - physiology
Ventricular Function, Left - physiology
Ventricular Remodeling - physiology
Abstract
Vascular hypertrophy and insulin resistance have been associated with abnormal left ventricular (LV) geometry in population studies. We wanted to investigate the influence of vascular hypertrophy and insulin resistance on LV hypertrophy and its function in patients with hypertension. In 89 patients with essential hypertension and electrocardiographic LV hypertrophy, we measured blood pressure; insulin sensitivity by hyperinsulinaemic euglucaemic clamp; minimal forearm vascular resistance (MFVR) by plethysmography; intima-media cross-sectional area of the common carotid arteries (IMA) by ultrasound; and LV mass, relative wall thickness (RWT), systolic function and diastolic filling by echocardiography after two weeks of placebo treatment. LV mass index correlated to IMA/height (r=0.36, P=0.001), serum insulin (r=-0.25, P
Notes
Comment In: J Hum Hypertens. 2003 May;17(5):299-30412756401
PubMed ID
12756402 View in PubMed
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Assessment of left ventricular function using mitral annular velocities in patients with congestive heart failure with or without the presence of significant mitral regurgitation.

https://arctichealth.org/en/permalink/ahliterature53588
Source
J Am Soc Echocardiogr. 2003 Mar;16(3):240-5
Publication Type
Article
Date
Mar-2003
Author
Mahbubul Alam
Johan Wardell
Eva Andersson
Rolf Nordlander
Bassem Samad
Author Affiliation
Department of Cardiology, Karolinska Institute at South Hospital, Södersjukhuset, Stockholm, Sweden. mahbubul.alam@medklin.sos.sll.se
Source
J Am Soc Echocardiogr. 2003 Mar;16(3):240-5
Date
Mar-2003
Language
English
Publication Type
Article
Keywords
Aged
Blood Flow Velocity - physiology
Comparative Study
Echocardiography, Doppler
Female
Heart Failure, Congestive - complications - physiopathology
Humans
Male
Mitral Valve - physiopathology - ultrasonography
Mitral Valve Insufficiency - complications - physiopathology
Myocardial Contraction - physiology
Research Support, Non-U.S. Gov't
Sensitivity and specificity
Severity of Illness Index
Statistics
Stroke Volume - physiology
Sweden
Tricuspid Valve - physiopathology - ultrasonography
Ventricular Dysfunction, Left - physiopathology
Ventricular Function, Left - physiology
Abstract
Myocardial velocities in patients with congestive heart failure (CHF) were studied using pulsed wave Doppler tissue imaging. Velocities were recorded at the mitral and tricuspid annulus. Four sites at the mitral annuli were selected corresponding to the septal, lateral, inferior, and anterior walls of the left ventricle from apical 4- and 2-chamber views. A mean value from the above 4 sites was selected to describe the mitral annular velocities. Only one site of the tricuspid annulus was selected, corresponding to the right ventricular free wall. Three different annular velocities were recorded: the peak systolic, and the peak early and late diastolic velocities. A total of 96 patients were compared with 12 age-matched healthy participants. Patients with CHF had significantly decreased mitral and tricuspid systolic velocities compared with healthy participants (4.9 vs 9.3 cm/s, P
PubMed ID
12618732 View in PubMed
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The association between glomerular filtration rate and left ventricular function in two independent community-based cohorts of elderly.

https://arctichealth.org/en/permalink/ahliterature264091
Source
Nephrol Dial Transplant. 2014 Nov;29(11):2069-74
Publication Type
Article
Date
Nov-2014
Author
Elisabet Nerpin
Erik Ingelsson
Ulf Risérus
Johan Sundström
Bertil Andren
Elisabeth Jobs
Anders Larsson
Lind Lars
Johan Ärnlöv
Source
Nephrol Dial Transplant. 2014 Nov;29(11):2069-74
Date
Nov-2014
Language
English
Publication Type
Article
Keywords
Aged
Cardio-Renal Syndrome - diagnosis - epidemiology - physiopathology
Cross-Sectional Studies
Disease Progression
Echocardiography
Female
Geriatric Assessment - methods
Glomerular Filtration Rate - physiology
Heart Ventricles - physiopathology - ultrasonography
Humans
Incidence
Male
Prognosis
Prospective Studies
Risk factors
Stroke Volume - physiology
Sweden - epidemiology
Ventricular Function, Left - physiology
Abstract
The cardiorenal syndrome, the detrimental bi-directional interplay between symptomatic heart failure and chronic kidney disease, is a major clinical challenge. Nonetheless, it is unknown if this interplay begins already at an asymptomatic stage. Therefore we investigated whether the glomerular filtration rate (GFR) is associated with left ventricular function in participants free from clinical heart failure and with a left ventricular ejection fraction (LVEF) >40% and with pre-specified sub-group analyses in individuals with a GFR >60 mL/min/m(2).
Two independent community-based cohorts were used; the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS; n = 911; 50% women; mean age: 70 years) and the Uppsala Longitudinal Study of Adult Men (ULSAM; n = 538; mean age: 71 years). We investigated cross-sectional association between cystatin C-based GFR (estimated glomerular function [eGFR]) and systolic (LVEF), diastolic- (isovolumic relaxation time [IVRT]) and global left ventricular function (myocardial performance index [MPI]) determined by echocardiography.
In both PIVUS and ULSAM, higher eGFR was significantly associated with higher LVEF (P = 0.004 [PIVUS] and P = 0.005 [ULSAM]). In PIVUS, higher eGFR was significantly associated with lower IVRT (P = 0.001) and MPI (P = 0.006), in age- and sex-adjusted models. After further adjustment for cardiovascular risk factors, the association between higher eGFR and higher LVEF was still statistically significant (P = 0.008 [PIVUS] and P = 0.02 [ULSAM]). In PIVUS, the age- and sex-adjusted association between eGFR and left ventricular function was similar in participants with eGFR >60 mL/min/m(2).
Our data suggest that the interplay between kidney and heart function begins prior to the development of symptomatic heart failure and kidney disease.
Notes
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Comment In: Nephrol Dial Transplant. 2014 Nov;29(11):1989-9125209365
PubMed ID
24916339 View in PubMed
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Association of carotid arterial distensibility with Doppler indices of left ventricular filling in 50-year-old subjects.

https://arctichealth.org/en/permalink/ahliterature52675
Source
Clin Physiol. 1997 Nov;17(6):579-90
Publication Type
Article
Date
Nov-1997
Author
T. Kangro
T. Jonason
E. Henriksen
I. Ringqvist
Author Affiliation
Department of Clinical Physiology, Central Hospital, Västerås, Sweden.
Source
Clin Physiol. 1997 Nov;17(6):579-90
Date
Nov-1997
Language
English
Publication Type
Article
Keywords
Blood Pressure - physiology
Carotid Arteries - physiology - ultrasonography
Cholesterol - blood
Echocardiography, Doppler
Electrocardiography
Female
Heart Rate - physiology
Humans
Male
Middle Aged
Reference Values
Smoking - physiopathology
Sweden
Triglycerides - blood
Ventricular Function, Left - physiology
Abstract
Doppler indices of left ventricular diastolic filling are associated with various cardiac and extracardiac factors. Afterload is one of the extracardiac factors influencing left ventricular diastolic filling. The distensibility of the great arteries is one of the components of afterload. In this study, the relation between Doppler indices of left ventricular filling and the distensibility of the common carotid arteries was investigated. We studied 237 subjects at 50 years of age with Doppler echocardiography and ultrasound examination of the common carotid arteries. The following Doppler indices of left ventricular filling were studied: peak early diastolic velocity E-wave, peak atrial diastolic velocity A-wave and early to atrial peak velocity ratio, E/A. Carotid arterial characteristics were: distensibility coefficient, carotid arterial diameter change in systole and fractional change in the carotid arterial diameter. The relation between Doppler indices of left ventricular filling and carotid arterial characteristics was assessed by univariate and multivariate regression analysis. There was a significant univariate, positive association between E/A ratio and carotid arterial distensibility (r = 0.27, P
PubMed ID
9413645 View in PubMed
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Associations between disease severity, coping and dimensions of health-related quality of life in patients admitted for elective coronary angiography - a cross sectional study.

https://arctichealth.org/en/permalink/ahliterature93099
Source
Health Qual Life Outcomes. 2008;6:38
Publication Type
Article
Date
2008
Author
Ulvik Bjørg
Nygård Ottar
Hanestad Berit R
Wentzel-Larsen Tore
Wahl Astrid K
Author Affiliation
Faculty of Health and Social Sciences, Bergen University College, Bergen, Norway. Bjorg.Ulvik@hib.no
Source
Health Qual Life Outcomes. 2008;6:38
Date
2008
Language
English
Publication Type
Article
Keywords
Adaptation, Physiological
Aged
Angina Pectoris - complications
Coronary Angiography
Coronary Artery Disease - classification - complications - psychology - radiography
Cross-Sectional Studies
Dyspnea - complications
Female
Health status
Heart Catheterization
Humans
Logistic Models
Male
Middle Aged
Norway
Patient Admission
Quality of Life - psychology
Questionnaires
Severity of Illness Index
Ventricular Function, Left - physiology
Abstract
BACKGROUND: In patients with suspected coronary artery disease (CAD), the overall aim was to analyse the relationships between disease severity and both mental and physical dimensions of health related quality of life (HRQOL) using a modified version of the Wilson and Cleary model. METHODS: Using a cross-sectional design, 753 patients (74% men), mean age 62 years, referred for elective cardiac catheterisation were included. The measures included 1) physiological factors 2) symptoms (disease severity, self-reported symptoms, anxiety and depression 3) self-reported functional status, 4) coping, 5) perceived disease burden, 6) general health perception and 7) overall quality of life. To analyse relationships, we performed linear and ordinal logistic regressions. RESULTS: CAD and left ventricular ejection fraction (LVEF) were significantly associated with symptoms of angina pectoris and dyspnea. CAD was not related to symptoms of anxiety and depression, but less depression was found in patients with low LVEF. Angina pectoris and dyspnea were both associated with impaired physical function, and dyspnea was also negatively related to social function. Overall, less perceived burden and better overall QOL were observed in patients using more confronting coping strategy. CONCLUSION: The present study demonstrated that data from cardiac patients to a large extent support the suggested model by Wilson and Cleary.
PubMed ID
18510727 View in PubMed
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[Bioelectrical activity of the myocardium in children born to parents irradiated during the Chernobyl disaster with isolated abnormal chords of the left ventricle].

https://arctichealth.org/en/permalink/ahliterature101599
Source
Lik Sprava. 2010 Oct-Dec;(7-8):16-21
Publication Type
Article
Author
V H Kondrashova
Source
Lik Sprava. 2010 Oct-Dec;(7-8):16-21
Language
Ukrainian
Publication Type
Article
Keywords
Abnormalities, Radiation-Induced - etiology - physiopathology - ultrasonography
Chernobyl Nuclear Accident
Child
Chordae Tendineae - abnormalities - radiation effects - ultrasonography
Echocardiography
Electrocardiography
Female
Heart Defects, Congenital - etiology - physiopathology - ultrasonography
Heart Ventricles - abnormalities - radiation effects - ultrasonography
Humans
Male
Maternal Exposure - adverse effects
Paternal Exposure - adverse effects
Pregnancy
Ventricular Function, Left - physiology - radiation effects
Abstract
A total 156 children of the main group (children born to parents irradiated during the Chernobyl disaster), who according to echocardiography revealed a different number of isolated abnormal chords of the left ventricle, 20 healthy children, 24 children of nosological control group and 50 children of referent group have been observed. It was found that isolated AHLV in children born to irradiated parents, was associated with changes in standard ECG, reflecting the presence of arrhythmias or predictors of their development. No significant differences in subgroups of children with different number of isolated AHLV have been established. Children with isolated AHLV born to parents irradiated during the Chernobyl accident, as all patients with minor structural anomalies of the heart, should be refered to a risk group in connection with the possibility of the development, in the first place, ventricular extrasystoles, paroxysmal ventricular tachycardia. Early diagnosis of isolated AHLV will allow to assess the outlook for further course of the disease and develop a plan of treatment and preventive measures.
PubMed ID
21714281 View in PubMed
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[Clinical and instrumental predictors of survival in patients with chronic heart failure and intact systolic left ventricle function]

https://arctichealth.org/en/permalink/ahliterature52953
Source
Lik Sprava. 2003 Oct-Nov;(7):28-31
Publication Type
Article
Author
L G Voronkov
G V Ianovskii
E V Ustimenko
O I Semenenko
Source
Lik Sprava. 2003 Oct-Nov;(7):28-31
Language
Russian
Publication Type
Article
Keywords
Adult
Aged
Cardiac Output, Low - mortality - physiopathology - ultrasonography
Chronic Disease
Disease-Free Survival
Echocardiography
English Abstract
Heart Ventricles - physiology - ultrasonography
Humans
Middle Aged
Ukraine - epidemiology
Ventricular Function, Left - physiology
Abstract
165 patients with clinically-manifested chronic heart failure (CHF) and preserved (ejection fraction--EF > 40%) left ventricular (LV) systolic function have been investigated. 135 of them have ischaemic heart disease (IHD) and high blood pressure, 8 patients are without IHD and 22 patients with normal blood pressure. 62 patients have chronic atrial fibrillation. Survival value in patients with CHF and preserved LV systolic function was compared to survival value of those with CHF and impaired ejection fraction (EF
PubMed ID
14723130 View in PubMed
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72 records – page 1 of 8.