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A 3-year follow-up after anterior colporrhaphy compared with collagen-coated transvaginal mesh for anterior vaginal wall prolapse: a randomised controlled trial.

https://arctichealth.org/en/permalink/ahliterature272920
Source
BJOG. 2016 Jan;123(1):136-42
Publication Type
Article
Date
Jan-2016
Author
M. Rudnicki
E. Laurikainen
R. Pogosean
I. Kinne
U. Jakobsson
P. Teleman
Source
BJOG. 2016 Jan;123(1):136-42
Date
Jan-2016
Language
English
Publication Type
Article
Keywords
Collagen
Denmark - epidemiology
Dyspareunia - epidemiology - etiology
Female
Finland - epidemiology
Follow-Up Studies
Gynecologic Surgical Procedures - instrumentation - methods
Humans
Norway - epidemiology
Pelvic Organ Prolapse - epidemiology - surgery
Prospective Studies
Quality of Life
Surgical Mesh
Surveys and Questionnaires
Sweden - epidemiology
Treatment Outcome
Vagina - surgery
Abstract
To compare the 1-year (previously published) and 3-year objective and subjective cure rates, and complications, related to the use of a collagen-coated transvaginal mesh for anterior vaginal wall prolapse against a conventional anterior repair.
Randomised controlled study.
Six departments of obstetrics and gynaecology in Norway, Sweden, Finland, and Denmark.
A total of 138 women, of 55 years of age or older, admitted for stage =2 anterior vaginal wall prolapse.
The women scheduled for primary anterior vaginal wall prolapse surgery were randomised between conventional anterior colporrhaphy and surgery with a collagen-coated prolene mesh. All patients were evaluated using the Pelvic Organ Prolapse Quantification (POP-Q) assessment before and after surgery. Symptoms related to pelvic organ prolapse were evaluated using the Pelvic Floor Impact Questionnaire (PFIQ-7) and the Pelvic Floor Distress Inventory (PFDI-20).
Objective cure, defined as POP-Q stage
PubMed ID
26420345 View in PubMed
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The absence of vaginal human papillomavirus 16 DNA in women who have not experienced sexual intercourse.

https://arctichealth.org/en/permalink/ahliterature218229
Source
Obstet Gynecol. 1994 May;83(5 Pt 1):735-7
Publication Type
Article
Date
May-1994
Author
E. Rylander
L. Ruusuvaara
M W Almströmer
M. Evander
G. Wadell
Author Affiliation
Health Unit for School Children, Stockholm, Sweden.
Source
Obstet Gynecol. 1994 May;83(5 Pt 1):735-7
Date
May-1994
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Child
Coitus
DNA Probes, HPV
DNA, Viral - analysis
Female
Humans
Papillomaviridae - genetics - isolation & purification
Vagina - virology
Abstract
To determine whether young women who have not experienced sexual intercourse may harbor genital human papillomavirus (HPV) infection in the vaginal-ectocervical mucosa.
We included 151 women, 10-25 years of age, attending two adolescent health care units (Stockholm and Uppsala) and one primary health care center (Umeå). The size of the hymenal orifice, use of tampons, and the habit of digital vaginal manipulation were registered. Samples of epithelial cells were collected from the vagina and analyzed for the presence of HPV using polymerase chain reaction.
One hundred thirty of 154 samples contained an adequate number of cells. Two samples were HPV 6 DNA-positive. None were HPV 16 DNA-positive. None of the women had external genital warts. In 84%, the hymenal opening was 15 mm or less. Forty-eight percent of the women used tampons during periods. Fifty-four percent had inserted their own finger into the vagina and in 23%, a boyfriend's finger had penetrated the vagina.
Human papillomavirus is rarely present vaginally in virginal women, even with the use of tampons or digital penetration.
PubMed ID
8164934 View in PubMed
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Accuracy of rapid antigen detection test for group B streptococci in the indigenous vaginal bacterial flora.

https://arctichealth.org/en/permalink/ahliterature199127
Source
Arch Gynecol Obstet. 1999 Nov;263(1-2):34-6
Publication Type
Article
Date
Nov-1999
Author
G G Donders
A. Vereecken
G. Salembier
B. Spitz
Author Affiliation
Department of Obstetrics and Gynecology, University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Belgium.
Source
Arch Gynecol Obstet. 1999 Nov;263(1-2):34-6
Date
Nov-1999
Language
English
Publication Type
Article
Keywords
Bacteriological Techniques
Female
Humans
Immunoenzyme Techniques
Sensitivity and specificity
Streptococcal Infections - diagnosis - microbiology
Streptococcus agalactiae - isolation & purification
Vagina - microbiology
Vaginal Diseases - diagnosis - microbiology
Abstract
To test the sensitivity of the rapid group B streptococci (GBS) antigen test ICONR and compare its accuracy in women with vaginal enterococci or with non-specific disturbance of the lactobacillary flora.
The ICONR, aerobic culture and a microscopic wet mount evaluation were done on a vaginal sample in 254 unselected women presenting for routine gynecologic care in an academic hospital in Flanders, Belgium and tested by Chi2 [diagnostic odds ratio (DOR) and its 95 percent confidence limits].
Sensitivity of the test was 70%, specificity 99.5%. Prevalence of GBS was 10.6% overall, 23% in the group with abnormal vaginal flora and 7% in the normal group (p=0.002). Accuracy of the ICONR was not affected by abnormal vaginal flora, but was significantly lower in the presence of enterococci: the DOR decreased from 490 to 58, and the positive predictive value from 94 to 80%.
With a sensitivity of 70% the enzyme immunoassay ICONR does not appear to be suitable as a practical screening tool for detecting GBS carriage in normal or preterm laboring women. In the presence of enterococci the test performed less well, with a DOR falling by 8 to 9 fold. We presume this is due to lower specificity in vivo in the presence of enterococci, as non-specific disturbance of the lactobacillary flora did not interfere with test results.
PubMed ID
10728626 View in PubMed
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Acute intermittent porphyria in women: clinical expression, use and experience of exogenous sex hormones. A population-based study in northern Sweden.

https://arctichealth.org/en/permalink/ahliterature63498
Source
J Intern Med. 2003 Aug;254(2):176-83
Publication Type
Article
Date
Aug-2003
Author
C. Andersson
E. Innala
T. Bäckström
Author Affiliation
Department of Family Medicine, University Hospital, Umeå, Sweden. christer.andersson@fammed.umu.se
Source
J Intern Med. 2003 Aug;254(2):176-83
Date
Aug-2003
Language
English
Publication Type
Article
Keywords
Abortion, Spontaneous - etiology
Adolescent
Adult
Aged
Aged, 80 and over
Contraceptive Agents - therapeutic use
Contraceptives, Oral - therapeutic use
Drug Combinations
Estradiol - therapeutic use
Female
Hormone Replacement Therapy - methods
Humans
Menopause - physiology
Middle Aged
Porphyria, Acute Intermittent - complications - drug therapy - epidemiology
Pregnancy
Progesterone - therapeutic use
Retrospective Studies
Sweden - epidemiology
Vagina - drug effects
Abstract
OBJECTIVE: To describe the clinical expression of acute intermittent porphyria (AIP) in women, their use of exogenous sex hormones, and the effects on AIP. DESIGN: A retrospective population-based study. SUBJECTS: All women aged > or =18 years (n = 190) with DNA-diagnosed AIP in northern Sweden. RESULTS: A total of 166 women (87%) participated; 91 (55%) had manifest AIP. Severe attacks were reported by 82%; 39% reported recurrent premenstrual AIP attacks and 22% reported chronic AIP symptoms. Oral hormonal contraceptives had been used by 58% of all these women and by 50 with manifest AIP (57%). Twelve women (24%) associated oral contraceptives as precipitating AIP attacks; in nine cases their first attack. One woman experienced relief from AIP symptoms. On commencing their treatment, 72% of the women with manifest AIP had not yet suffered their first attack. Twenty-two women (25%) aged > or =45 years had used hormonal replacement therapy (HRT) at menopause to remedy climacteric symptoms (the percutaneous route was most frequently used); no AIP attack was precipitated. HRT to remedy vaginal dryness was used by 26 women (28%) aged > or =45 years without triggering an AIP attack. Miscarriages were more frequent in women with manifest AIP (50%) than in the latent group (30%, P = 0.014). CONCLUSIONS: About half of the women with AIP had used oral hormonal contraceptives. As 25% of women with manifest AIP reported attacks associated with such drugs, caution must still be recommended. Menopausal HRT only rarely affected the disorder. Miscarriage was more common amongst women with manifest AIP.
PubMed ID
12859699 View in PubMed
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Anatomic and functional assessment and risk factors of recurrent prolapse after vaginal sacrospinous fixation.

https://arctichealth.org/en/permalink/ahliterature185342
Source
Acta Obstet Gynecol Scand. 2003 May;82(5):471-8
Publication Type
Article
Date
May-2003
Author
Kari Nieminen
Heini Huhtala
Pentti K Heinonen
Author Affiliation
Department of Obstetrics and Gynecology, Tampere University Hospital and Medical School and School of Public Health, University of Tampere, Tampere, Finland. kn37975@uta.fi
Source
Acta Obstet Gynecol Scand. 2003 May;82(5):471-8
Date
May-2003
Language
English
Publication Type
Article
Keywords
Activities of Daily Living
Aged
Aged, 80 and over
Antibiotic Prophylaxis
Broad Ligament - surgery
Female
Finland
Gynecologic Surgical Procedures - adverse effects - methods
Humans
Middle Aged
Multivariate Analysis
Pelvic Floor - surgery
Proportional Hazards Models
Pulmonary Embolism - etiology
Quality of Life
Recurrence
Retrospective Studies
Risk factors
Sacrococcygeal Region - physiopathology - surgery
Time Factors
Urinary Tract Infections - etiology
Uterine Prolapse - physiopathology - surgery
Vagina - surgery
Abstract
To identify risk factors in recurrence and to evaluate anatomic and functional results of vaginal sacrospinous ligament fixation and pelvic floor reconstruction for genital prolapse.
One hundred and thirty-eight women underwent surgery for uterovaginal or vault prolapse. Follow-up data were available for 122 cases; 83% were examined and others were interviewed by telephone. The median (range) follow-up was 24 (1-141) months. Cox regression was used to identify risk factors associated with recurrence; uni- and multivariate regression was used to identify risk factors underlying postoperative infections because infections were found to be a risk factor of recurrence. Recurrence-free survival was estimated using the Kaplan-Meier method.
Seven (5%) patients suffered severe cardiopulmonary complications including one postoperative death due to a pulmonary embolism. Twenty-six (21%) patients suffered a recurrence, 14 with cystocele. Ten patients with recurrence were symptomatic and six underwent a re-operation. The Cox regression model showed that vaginal cuff infection raised the odds ratio (OR) for recurrence to 6.13 [confidence interval (CI) 1.80-20.83] and urinary tract infection to 3.65 (CI 1.40-9.47). In both uni- and multivariate analysis, lack of intravenous antibiotic prophylaxis, age less than 73 years and vaginal ulcerations were statistically significant risk factors for postoperative infection. Eleven (33%) out of 33 sexually active women reported improvement and three (9%) complained of dyspareunia.
Transvaginal sacrospinous ligament fixation with pelvic floor repair is an effective means of correcting both vault prolapse and uterine procidentia. Women who wish to preserve coital function will also benefit from this operation. Postoperative infection is an independent and most important individual risk factor underlying recurrence. Prophylactic antibiotics seem to be effective in reducing the rate of postoperative infections.
PubMed ID
12752079 View in PubMed
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[A new zoonosis--investigation of Gardnerella vaginalis disease of fox. III. Epidemiological investigation]

https://arctichealth.org/en/permalink/ahliterature4561
Source
Wei Sheng Wu Xue Bao. 1995 Jun;35(3):209-15
Publication Type
Article
Date
Jun-1995
Author
Z. Yan
X. Yan
F. Luan
C. Wang
Author Affiliation
Speciality Institute of CAAS, Jilin.
Source
Wei Sheng Wu Xue Bao. 1995 Jun;35(3):209-15
Date
Jun-1995
Language
Chinese
Publication Type
Article
Keywords
Abortion, Veterinary - epidemiology
Animals
Bacterial Infections - epidemiology - microbiology - veterinary
China - epidemiology
English Abstract
Female
Foxes - microbiology
Gardnerella vaginalis - classification - isolation & purification
Humans
Male
Pregnancy
Research Support, Non-U.S. Gov't
Vagina - microbiology
Zoonoses - epidemiology
Abstract
By epidemiological investigation to Gardnerella vaginalis disease of fox of civil main farms raising foxes, this disease was showed to be susceptible to silver foxes, arctic foxes, red foxes and color foxes, the disease was mostly transmitted by copulation, infected foxes played the leading role in epidemic of the disease. Investigative results of all farms raising foxes showed infection rate of fox groups was 0.9-21.9%, resulting in abortion rate was 1.5-14.7%, empty rate was 3.2-47.5%. Serious harm was revealed to the disease. By serology and causative agent isolation, we had proved that the disease was able to infect feeder and manager, it belongs to zoonosis. Racoondog. mink and canine infect with the disease besides fox. White mouse, big white rat, gopher, guinea pig and rabbit for laboratory are not infected with the disease.
PubMed ID
7631502 View in PubMed
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Ano-genital human papillomavirus type 97 infection is detected in Canadian men but not women at risk or infected with the human immunodeficiency virus.

https://arctichealth.org/en/permalink/ahliterature119545
Source
Virol J. 2012;9:243
Publication Type
Article
Date
2012
Author
Marie-Eve Landry
Irving E Salit
Catherine Rodrigues-Coutlée
Deborah Money
Anu Rebbapragada
Jill Tinmouth
Catherine Hankins
Isabelle Gorska-Flipot
Jacques Archambault
Eduardo L Franco
François Coutlée
Author Affiliation
Département de Pathologie, Centre Hospitalier de l'Université de Montréal, Montréal, Québec, Canada.
Source
Virol J. 2012;9:243
Date
2012
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Aged, 80 and over
Anal Canal - virology
Canada - epidemiology
Cohort Studies
DNA, Viral - genetics
Female
Genotype
HIV - isolation & purification
HIV Infections - complications - epidemiology - virology
HIV Seronegativity
HIV Seropositivity
Homosexuality, Male
Humans
Male
Middle Aged
Papillomaviridae - genetics - isolation & purification
Papillomavirus Infections - complications - diagnosis - virology
Polymorphism, Genetic
Prevalence
Risk
Sex Factors
Vagina - virology
Young Adult
Abstract
Human papillomavirus type 97 (HPV97) DNA was detected in nearly 5% of anal samples collected from HIV-seropositive men living in Montreal, Canada. The rate of detection of HPV97 in the genital tract of Canadian women is unknown. Whether HPV97 is a local epidemic in HIV-seropositive men living in Montreal is also unknown. The prevalence of human papillomavirus type 97 (HPV97) was assessed in cervicovaginal cells from women living in Canada and in anal samples from HIV-seropositive men living in Toronto.
Cervicovaginal lavages collected from 904 women (678 HIV-seropositive, 226 HIV-seronegative) women living in Canada and anal cells collected from 123 HIV-seropositive men living in Toronto were tested for the presence of HPV97 with PCR. HPV97-positive samples were further tested by PCR-sequencing for molecular variant analysis to assess if all HPV97-positive men were infected with the same strain. All cervicovaginal samples were negative for HPV97. HPV97 was detected in anal samples from 6 HIV-seropositive men (4.9%, 95% confidence interval 2.0-10.5%), of whom five had high-grade and one had low-grade anal intraepithelial neoplasia, in addition to 2 to 8 HPV genital genotypes per sample. Four HPV97 variants were defined by four variation sites in the viral control region.
These findings indicate that HPV97 infects in the anal canal of HIV-seropositive men but is not detected in the genital tract of women.
Notes
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PubMed ID
23092191 View in PubMed
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Anterior colporrhaphy compared with collagen-coated transvaginal mesh for anterior vaginal wall prolapse: a randomised controlled trial.

https://arctichealth.org/en/permalink/ahliterature106735
Source
BJOG. 2014 Jan;121(1):102-10; discussion 110-1
Publication Type
Article
Date
Jan-2014
Author
M. Rudnicki
E. Laurikainen
R. Pogosean
I. Kinne
U. Jakobsson
P. Teleman
Author Affiliation
Department of Obstetrics and Gynaecology, Roskilde University Hospital, Roskilde, Denmark.
Source
BJOG. 2014 Jan;121(1):102-10; discussion 110-1
Date
Jan-2014
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Collagen
Cystocele - surgery
Denmark
Female
Finland
Humans
Middle Aged
Norway
Quality of Life
Questionnaires
Sexuality
Surgical Mesh
Sweden
Treatment Outcome
Vagina - surgery
Abstract
To investigate the anatomical cure rate and complications related to collagen-coated mesh for cystocele, compared with a conventional anterior colporrhaphy.
A randomised controlled study.
Six departments of obstetrics and gynaecology in Norway, Sweden, Finland, and Denmark.
Women aged 55 years or older, referred for surgery with a prolapse of the anterior vaginal wall of stage 2 or higher.
Women scheduled for primary cystocoele surgery were randomised to either anterior colporrhaphy or a collagen-coated Prolene mesh. Power analysis indicated that 130 patients had to be randomised. All patients were evaluated using the Pelvic Organ Prolapse-Quantification (POP-Q) measurement. Quality of life, symptoms, and sexual function were evaluated using the Pelvic Floor Impact Questionnaire, the Pelvic Floor Distress Inventory, and the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire.
The primary outcome was objective cure, defined as prolapse below POP-Q stage 2 at the 12-months follow-up. Secondary outcomes were quality of life, symptoms, and presence (or not) of complications.
In total, 161 women were randomised to either anterior colporrhaphy or mesh (participant ages 64.9 ± 6.4 years versus 64.7 ± 6.6 years, respectively; mean ± SD). The objective cure rate was 39.8% (95% CI 28.6-50.9%) in the anterior colporrhaphy group, compared with 88.1% (95% CI 80.7-95.6%) in the mesh group (P
PubMed ID
24118844 View in PubMed
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Antibiotic use during pregnancy alters the commensal vaginal microbiota.

https://arctichealth.org/en/permalink/ahliterature261455
Source
Clin Microbiol Infect. 2014 Jul;20(7):629-35
Publication Type
Article
Date
Jul-2014
Author
J. Stokholm
S. Schjørring
C E Eskildsen
L. Pedersen
A L Bischoff
N. Følsgaard
C G Carson
B L K Chawes
K. Bønnelykke
A. Mølgaard
B. Jacobsson
K A Krogfelt
H. Bisgaard
Source
Clin Microbiol Infect. 2014 Jul;20(7):629-35
Date
Jul-2014
Language
English
Publication Type
Article
Keywords
Administration, Oral
Adult
Anti-Bacterial Agents - therapeutic use
Biota - drug effects
Denmark
Female
Humans
Pregnancy
Respiratory Tract Infections - drug therapy
Urinary Tract Infections - drug therapy
Vagina - microbiology
Abstract
Antibiotics may induce alterations in the commensal microbiota of the birth canal in pregnant women. Therefore, we studied the effect of antibiotic administration during pregnancy on commensal vaginal bacterial colonization at gestational week 36. Six hundred and sixty-eight pregnant women from the novel unselected Copenhagen Prospective Studies on Asthma in Childhood (COPSAC2010 ) pregnancy cohort participated in this analysis. Detailed information on oral antibiotic prescriptions during pregnancy filled at the pharmacy was obtained and verified prospectively. Vaginal samples were obtained at pregnancy week 36 and cultured for bacteria. Women who received oral antibiotics during any pregnancy trimester had an increased rate of colonization by Staphylococcus species in the vaginal samples as compared with samples obtained from women without any antibiotic treatment during pregnancy (adjusted OR 1.63, 95% CI 1.06-2.52, p 0.028). Oral antibiotic administration in the third trimester were also associated with increased colonization by Staphylococcus species (adjusted OR 1.98, 95% CI 1.04-3.76, p 0.037). These bacteriological changes were associated with urinary tract infection antibiotics. Women treated in the third trimester of pregnancy were more often colonized by Escherichia coli than women without antibiotic treatment in the third trimester (adjusted OR 1.91, 95% CI 1.04-3.52, p 0.038). This change was associated with respiratory tract infection (RTI) antibiotics. We did not observe any significant changes in vaginal Streptococcus agalactiae (group B streptoccocus) or Staphylococcus aureus colonization following antibiotic treatment in pregnancy. Antibiotic administration during pregnancy leads to alterations in the vaginal microbiological ecology prior to birth, with potential morbidity, and long-term effects on the early microbial colonization of the neonate.
PubMed ID
24118384 View in PubMed
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Antibodies to capsular polysaccharides of group B Streptococcus in pregnant Canadian women: relationship to colonization status and infection in the neonate.

https://arctichealth.org/en/permalink/ahliterature194114
Source
J Infect Dis. 2001 Aug 1;184(3):285-91
Publication Type
Article
Date
Aug-1-2001
Author
H D Davies
C. Adair
A. McGeer
D. Ma
S. Robertson
M. Mucenski
L. Kowalsky
G. Tyrell
C J Baker
Author Affiliation
Departments of Microbiology and Infectious Disease, Pediatrics, and Community Health Sciences and Child Health Research Unit, Alberta Children's Hospital, University of Calgary, Calgary,T2T-5C7, Canada. dele.davies@crha-health.ab.ca
Source
J Infect Dis. 2001 Aug 1;184(3):285-91
Date
Aug-1-2001
Language
English
Publication Type
Article
Keywords
Adult
Alberta
Antibodies, Bacterial - blood
Canada
Cohort Studies
Female
Humans
Immunoglobulin G - blood
Infant, Newborn
Infectious Disease Transmission, Vertical
Parity
Polysaccharides, Bacterial - immunology
Population Surveillance
Pregnancy
Pregnancy Complications, Infectious - microbiology
Rectum - microbiology
Serotyping
Streptococcal Infections - blood - immunology - transmission
Streptococcus agalactiae - immunology - isolation & purification
Vagina - microbiology
Abstract
In a cohort study of 1207 pregnant women in Alberta, Canada, the serotype distributions of vaginal-rectal group B Streptococcus (GBS) isolates were compared with all isolates from neonates with invasive GBS disease identified by population-based surveillance. Serum concentrations of Ia, Ib, II, III, and V capsular polysaccharide (CPS)-specific IgG also were determined, according to serotype of the vaginal-rectal colonizing GBS strain. GBS colonization was detected in 19.5% (235 of 1207) of women. Serotype III accounted for 20.6% (48 of 233) of colonizing strains available for typing but for 37% (27 of 73) of invasive isolates from neonates (P
PubMed ID
11443553 View in PubMed
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156 records – page 1 of 16.