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Cost effectiveness of diagnosis of deep vein thrombosis in symptomatic patients.

https://arctichealth.org/en/permalink/ahliterature214766
Source
Thromb Haemost. 1995 Jul;74(1):189-96
Publication Type
Article
Date
Jul-1995
Author
R D Hull
W. Feldstein
G F Pineo
G E Raskob
Author Affiliation
Department of Medicine, University of Calgary, Alberta, Canada.
Source
Thromb Haemost. 1995 Jul;74(1):189-96
Date
Jul-1995
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Aged, 80 and over
Algorithms
Anticoagulants - economics - therapeutic use
Canada
Cost Control
Cost-Benefit Analysis
Female
Health Care Costs
Heparin - economics - therapeutic use
Hospitals, University - economics
Humans
Male
Middle Aged
Phlebography - economics
Plethysmography, Impedance - economics
Predictive value of tests
Thrombophlebitis - diagnosis - drug therapy - economics - radiography - ultrasonography
Ultrasonography, Doppler - economics
United States
Warfarin - economics - therapeutic use
Abstract
The most widely used noninvasive test for deep vein thrombosis is Doppler ultrasonographic imaging of the lower extremities. The best evaluated of the noninvasive approaches are ascending contrast venography, impedance plethysmography, Doppler ultrasonography with B-mode imaging. Economic evaluation is aimed at helping decision makers to reach their goal of maximizing the health of the population served, subject to the available resources.
The data that provided the basis for this cost effectiveness analysis were derived from a prospective study of approximately 500 patients referred to a regional thromboembolism program with a first episode of clinically suspected deep vein thrombosis. The application of cost effectiveness analysis to the diagnosis of deep vein thrombosis is readily accomplished using cost minimization. This cost effectiveness technique makes it possible to rank the diagnostic approaches from "worst" to "best", with the best approach defined as that which accomplishes the desired health effect at minimum cost. Effectiveness (health benefit) may be defined in this context as the number or proportion of patients with deep vein thrombosis correctly identified by objective testing or, the number or proportion in whom treatment was correctly withheld.
Clinical diagnosis is cost ineffective; $1,590,784 Canadian, $2,624,220 US. Outpatient diagnosis using noninvasive testing was the most cost effective. Serial Doppler ultrasonography is more costly ($618,265 Canadian, $1,326,180 US) than serial impedance plethysmography ($527,165 Canadian, $1,052,880 US). Combined Doppler ultrasonography and serial impedance plethysmography offers a less costly strategy ($551,065 Canadian, $1,124,580 US) than serial ultrasonography alone.
Objective testing is mandatory. Outpatient testing is preferred, avoiding unnecessary hospital admissions. Noninvasive testing is the most cost effective. The most widely used test, serial Doppler ultrasonography, is less cost effective than serial impedance plethysmography. The combined approach of initial Doppler ultrasonography followed by serial impedance plethysmography combines the advantage of an initial ultrasound image with less costly serial impedance plethysmography.
PubMed ID
8578456 View in PubMed
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Illustrative estimates of costs and effects of the use of Doppler ultrasonography in high-risk pregnancies.

https://arctichealth.org/en/permalink/ahliterature63380
Source
Int J Technol Assess Health Care. 2003;19(4):624-31
Publication Type
Article
Date
2003
Author
Hanne Brix Westergaard
Jan Sørensen
Jens Langhoff-Roos
Author Affiliation
Department of Obstetrics, Copenhagen University Hospital, Rigshospitalet, Denmark. hbw@dadlnet.dk
Source
Int J Technol Assess Health Care. 2003;19(4):624-31
Date
2003
Language
English
Publication Type
Article
Keywords
Cost-Benefit Analysis
Denmark
Diagnostic Techniques, Obstetrical and Gynecological - economics - utilization
Female
Fetal Growth Retardation - economics
Humans
Models, Economic
Patient satisfaction
Pregnancy
Pregnancy outcome
Pregnancy, High-Risk
Research Support, Non-U.S. Gov't
Ultrasonography, Doppler - economics - utilization
Abstract
OBJECTIVES: To examine the cost-effectiveness of Doppler ultrasonography in high-risk pregnancies. METHODS: An analysis was made of the cost-effectiveness of Doppler ultrasonography in high-risk pregnancies in relation to different organizational models. National costs of Doppler ultrasonography for singleton pregnancies with intrauterine growth retardation were estimated for three models. The cost-effectiveness analysis was based on results from a meta-analysis on clinical effects, patient costs, immediate health care costs, and costs per "saved" perinatal death. RESULTS: In the decentralized model (the current situation in Denmark), incremental health care costs were estimated to be 13.5 million DKK, with patient costs set at zero. In the regional and centralized models, the estimated costs were 9.3 million/0.9 million DKK and 3.4 million/2.6 million DKK, respectively. The incremental costs were more than outweighed by the savings made from significant reductions in obstetric interventions. The centralized model dominated the other two models in the cost-effective analysis. In the decentralized model, the costs of avoiding one perinatal death were estimated to be 1 million DKK. The sensitivity analysis suggested that the cost-effectiveness ratio differed considerably, depending on the assumptions used, although the rank order of the three models did not change. CONCLUSIONS: The cost-effectiveness analysis showed that a centralized model with five obstetric centers offering Doppler ultrasonography dominates the regional and decentralized models. However, even with the decentralized model (which reflects the current situation in Denmark), the costs of avoiding one perinatal death would seem to be reasonable. In view of the paucity of available cost and effects data and the sensitivity of the results to changes in the assumptions made, more reliable information is needed before a decision can be made regarding the organization of Doppler ultrasonography for high-risk pregnancies.
PubMed ID
15095768 View in PubMed
Less detail

Symptoms of neck artery compromise: case presentations of risk estimate for treatment.

https://arctichealth.org/en/permalink/ahliterature206291
Source
J Manipulative Physiol Ther. 1998 Feb;21(2):128
Publication Type
Article
Date
Feb-1998