Skip header and navigation

Refine By

4709 records – page 1 of 471.

[1st case of adiaspiromycosis in the ZSSR]

https://arctichealth.org/en/permalink/ahliterature42754
Source
Cesk Dermatol. 1975 Feb;50(1):9-12
Publication Type
Article
Date
Feb-1975

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) poisoning in Victor Yushchenko: identification and measurement of TCDD metabolites.

https://arctichealth.org/en/permalink/ahliterature95137
Source
Lancet. 2009 Oct 3;374(9696):1179-85
Publication Type
Article
Date
Oct-3-2009
Author
Sorg O.
Zennegg M.
Schmid P.
Fedosyuk R.
Valikhnovskyi R.
Gaide O.
Kniazevych V.
Saurat J-H
Author Affiliation
Dermato-Toxicology, Swiss Centre for Applied Human Toxicology, and Department of Dermatology, University Hospital, Geneva, Switzerland.
Source
Lancet. 2009 Oct 3;374(9696):1179-85
Date
Oct-3-2009
Language
English
Publication Type
Article
Keywords
Adipose Tissue - chemistry
Biopsy
Drug Residues - analysis - metabolism
Fatal Outcome
Feces - chemistry
Forensic Medicine - methods
Half-Life
Homicide
Humans
Male
Middle Aged
Politics
Substance Abuse Detection - methods
Sweat - chemistry
Tetrachlorodibenzodioxin - analysis - chemistry - metabolism - poisoning
Time Factors
Ukraine
Abstract
BACKGROUND: 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has a long half-life of 5-10 years in human beings as a result of its high lipophilicity, and little or no metabolism. We monitored TCDD, its form, distribution, and elimination in Victor Yushchenko after he presented with severe poisoning. METHODS: In late December, 2004, a patient presented with TCDD poisoning; the levels in his blood serum (108000 pg/g lipid weight) were more than 50 000-fold greater than those in the general population. We identified TCDD and its metabolites, and monitored their levels for 3 years using gas chromatography and high-resolution mass spectrometry in samples of blood serum, adipose tissue, faeces, skin, urine, and sweat, after they were extracted and cleaned with different organic solvents. FINDINGS: The amount of unmodified TCDD in the samples that were analysed accounted for about 60% of TCDD eliminated from the body during the same period. Two TCDD metabolites-2,3,7-trichloro-8-hydroxydibenzo-p-dioxin and 1,3,7,8-tetrachloro-2-hydroxydibenzo-p-dioxin-were identified in the faeces, blood serum, and urine. The faeces contained the highest concentration of TCDD metabolites, and were the main route of elimination. Altogether, the different routes of elimination of TCDD and its metabolites accounted for 98% of the loss of the toxin from the body. The half-life of TCDD in our patient was 15.4 months. INTERPRETATION: This case of poisoning with TCDD suggests that the design of methods for routine assessment of TCDD metabolites in human beings should be a main aim of TCDD research in the metabolomic era. FUNDING: University of Geneva Dermatology Fund, and Swiss Centre for Applied Human Toxicology.
Notes
Comment In: Lancet. 2009 Oct 3;374(9696):1131-219660808
PubMed ID
19660807 View in PubMed
Less detail
Source
Nature. 1987 Feb 12-18;325(6105):569
Publication Type
Article
Source
Nature. 1987 Feb 12-18;325(6105):569
Language
English
Publication Type
Article
Keywords
Accidents
Humans
Neoplasms - mortality
Nuclear Reactors
Ukraine
PubMed ID
3808056 View in PubMed
Less detail

[4 years after Chernobyl: medical repercussions]

https://arctichealth.org/en/permalink/ahliterature25355
Source
Bull Cancer. 1990;77(5):419-28
Publication Type
Article
Date
1990
Author
D. Hubert
Source
Bull Cancer. 1990;77(5):419-28
Date
1990
Language
French
Publication Type
Article
Keywords
Abnormalities, Radiation-Induced - epidemiology
Abortion, Habitual - epidemiology
Blood Cell Count
Bone Marrow Transplantation
Decontamination - methods
Diarrhea - etiology
English Abstract
Europe
Female
Humans
Male
Nuclear Reactors
Pregnancy
Prognosis
Psychophysiologic Disorders - etiology
Pulmonary Fibrosis - etiology
Radiation Dosage
Radiation Injuries - complications - epidemiology - therapy
Skin - radiation effects
Triage
Ukraine
Abstract
The nuclear accident at Chernobyl accounted for an acute radiation syndrome in 237 persons on the site. Triage was the initial problem and was carried out according to clinical and biological criteria; evaluating the doses received was based on these criteria. Thirty one persons died and only 1 survived a dose higher than 6 Gy. Skin radiation burns which were due to inadequate decontamination, greatly worsened prognosis. The results of 13 bone marrow transplantations were disappointing, with only 2 survivors. Some time after the accident, these severely irradiated patients are mainly suffering from psychosomatic disorders, in the USSR, some areas have been significantly contaminated and several measures were taken to mitigate the impact on population: evacuating 135,000 persons, distributing prophylactic iodine, establishing standards and controls on foodstuff. Radiation phobia syndrome which developed in many persons, is the only sanitary effect noticed up to now. Finally, in Europe, there was only an increase in induced abortions and this was totally unwarranted. If we consider the risk of radiation induced cancer, an effect might not be demonstrated.
PubMed ID
2205311 View in PubMed
Less detail

[5-day work week in antitubercular dispensaries in the Ukrainian SSR]

https://arctichealth.org/en/permalink/ahliterature70111
Source
Probl Tuberk. 1970;48(6):14-7
Publication Type
Article
Date
1970
Author
N A Maslenkova
Source
Probl Tuberk. 1970;48(6):14-7
Date
1970
Language
Russian
Publication Type
Article
Keywords
Ambulatory Care
Health Facilities - utilization
Humans
Time Factors
Tuberculosis - therapy
Ukraine
PubMed ID
5447926 View in PubMed
Less detail

5. Nonmalignant diseases after the Chernobyl catastrophe.

https://arctichealth.org/en/permalink/ahliterature146767
Source
Ann N Y Acad Sci. 2009 Nov;1181:58-160
Publication Type
Article
Date
Nov-2009
Author
Alexey V Yablokov
Author Affiliation
Russian Academy of Sciences, Leninsky Prospect 33, Office 319, 119071 Moscow, Russia. Yablokov@ecopolicy.ru
Source
Ann N Y Acad Sci. 2009 Nov;1181:58-160
Date
Nov-2009
Language
English
Publication Type
Article
Keywords
Chernobyl Nuclear Accident
Humans
Radiation Injuries - epidemiology - genetics - immunology - metabolism
Republic of Belarus - epidemiology
Russia - epidemiology
Ukraine - epidemiology
Abstract
This section describes the spectrum and the scale of the nonmalignant diseases that have been found among exposed populations. Adverse effects as a result of Chernobyl irradiation have been found in every group that has been studied. Brain damage has been found in individuals directly exposed--liquidators and those living in the contaminated territories, as well as in their offspring. Premature cataracts; tooth and mouth abnormalities; and blood, lymphatic, heart, lung, gastrointestinal, urologic, bone, and skin diseases afflict and impair people, young and old alike. Endocrine dysfunction, particularly thyroid disease, is far more common than might be expected, with some 1,000 cases of thyroid dysfunction for every case of thyroid cancer, a marked increase after the catastrophe. There are genetic damage and birth defects especially in children of liquidators and in children born in areas with high levels of radioisotope contamination. Immunological abnormalities and increases in viral, bacterial, and parasitic diseases are rife among individuals in the heavily contaminated areas. For more than 20 years, overall morbidity has remained high in those exposed to the irradiation released by Chernobyl. One cannot give credence to the explanation that these numbers are due solely to socioeconomic factors. The negative health consequences of the catastrophe are amply documented in this chapter and concern millions of people.
PubMed ID
20002045 View in PubMed
Less detail

The 6th Klaas Breur memorial lecture, 1987. The Chernobyl accident--impact Western Europe.

https://arctichealth.org/en/permalink/ahliterature25858
Source
Radiother Oncol. 1988 May;12(1):1-13
Publication Type
Article
Date
May-1988

[7 years' experience in organizing sanatorium wards for children with rheumatism in a rural locale of Lvov Province]

https://arctichealth.org/en/permalink/ahliterature43746
Source
Pediatr Akus Ginekol. 1972;4:27
Publication Type
Article
Date
1972
Author
V P Ferents
Iu V Manchenko
Source
Pediatr Akus Ginekol. 1972;4:27
Date
1972
Language
Ukrainian
Publication Type
Article
Keywords
Child
Hospitals, Special
Humans
Rheumatic Diseases - therapy
Rural Health
Ukraine
PubMed ID
4545065 View in PubMed
Less detail

[10 years' experience in the long-distance transportation of myocardial infarct patients in a rural locality]

https://arctichealth.org/en/permalink/ahliterature56043
Source
Kardiologiia. 1978 Jan;18(1):127-9
Publication Type
Article
Date
Jan-1978

15 years after Chernobyl: new evidence of thyroid cancer.

https://arctichealth.org/en/permalink/ahliterature19395
Source
Lancet. 2001 Dec 8;358(9297):1965-6
Publication Type
Article
Date
Dec-8-2001
Author
Y. Shibata
S. Yamashita
V B Masyakin
G D Panasyuk
S. Nagataki
Source
Lancet. 2001 Dec 8;358(9297):1965-6
Date
Dec-8-2001
Language
English
Publication Type
Article
Keywords
Accidents, Radiation
Adolescent
Byelarus - epidemiology
Child
Female
Humans
Male
Mass Screening
Neoplasms, Radiation-Induced - epidemiology
Nuclear Reactors
Population Surveillance
Radioactive fallout
Research Support, Non-U.S. Gov't
Thyroid Neoplasms - epidemiology - etiology
Ukraine - epidemiology
Abstract
The Chernobyl nuclear power plant accident happened on April 26, 1986. We investigated the cause of the striking increase in frequency of thyroid cancer in children who lived within a 150 km radius of Chernobyl and who were born before and after the accident. No thyroid cancer was seen in 9472 children born in 1987-89, whereas one and 31 thyroid cancers were recorded in 2409 children born April 27, 1986, to Dec 31, 1986, and 9720 born Jan 1, 1983, to April 26, 1986, respectively. Short-lived radioactive fallout caused by the Chernobyl accident probably induced thyroid cancer in children living near Chernobyl.
PubMed ID
11747925 View in PubMed
Less detail

4709 records – page 1 of 471.