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115 records – page 1 of 12.

Actual practice vs guidelines in laboratory monitoring of older patients with primary hypothyroidism in primary care.

https://arctichealth.org/en/permalink/ahliterature169851
Source
Aging Clin Exp Res. 2006 Feb;18(1):34-9
Publication Type
Article
Date
Feb-2006
Author
Seija I Eskelinen
Raimo E Isoaho
Sirkka-Liisa Kivelä
Kerttu M Irjala
Author Affiliation
Department of Family Medicine, University of Turku, Lemminkiisenkatu 1, FIN-20014 Turku, Finland. seija.eskelinen@utu.fi
Source
Aging Clin Exp Res. 2006 Feb;18(1):34-9
Date
Feb-2006
Language
English
Publication Type
Article
Keywords
Adult
Aged
Female
Finland
Follow-Up Studies
Guidelines as Topic
Hormone Replacement Therapy
Humans
Hypothyroidism - blood - therapy
Laboratories - standards
Male
Middle Aged
Primary Health Care
Thyroid Function Tests
Thyrotropin-Releasing Hormone - blood
Thyroxine - blood - therapeutic use
Abstract
Clinical guidelines are produced in order to achieve an acceptable standard of care, especially for patients with common diseases in primary care. The treatment of primary hypothyroidism serves as an example of the content of clinical guidelines and actual practice. The aim of this study was to compare the follow-up of primary hypothyroidism by thyroid function tests, serum TSH and serum-free T4, in older patients managed in primary care, with recommendations in treatment guidelines and textbooks.
Participation rate 82% (n=1260), mean age 74 years, (range 64-100 yrs). Patients with primary hypothyroidism were identified by means of cross-sectional survey (Lieto Study 1998-1999) and 4-year retrospective collection of laboratory database medical records (1994-1998), performed in autumn 2003.
In most stable (=treated for more than 14 months) thyroxine users, both serum TSH (mean 1.4 measurements/year) and serum-free T4 (mean 0.8 measurements/year) values were measured over the 4-year period of thyroxine treatment. 66.4% of serum TSH and 85.3% of serum-free T4 values were within normal range. 41.7% of serum-free T4 determinations had been performed without indication (=with TSH in normal range).
Compared with the recommended testing frequency given in various guidelines, a considerable number of extra measurements, especially serum-free T4, were performed. However, some key issues in the recommendations were difficult to interpret, and the age or other main characteristics of the patient were not taken into consideration adequately.
PubMed ID
16608134 View in PubMed
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The association between hypoechogenicity or irregular echo pattern at thyroid ultrasonography and thyroid function in the general population.

https://arctichealth.org/en/permalink/ahliterature167366
Source
Eur J Endocrinol. 2006 Oct;155(4):547-52
Publication Type
Article
Date
Oct-2006
Author
Pernille Vejbjerg
Nils Knudsen
Hans Perrild
Peter Laurberg
Inge Bülow Pedersen
Lone B Rasmussen
Lars Ovesen
Torben Jørgensen
Author Affiliation
Department of Internal Medicine I, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark. pervej01@glostruphosp.kbhamt.dk
Source
Eur J Endocrinol. 2006 Oct;155(4):547-52
Date
Oct-2006
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Autoantibodies - blood
Autoantigens - immunology
Cross-Sectional Studies
Denmark
Female
Humans
Hyperthyroidism - ultrasonography
Hypothyroidism - ultrasonography
Image Processing, Computer-Assisted - statistics & numerical data
Iodide Peroxidase - immunology
Iron-Binding Proteins - immunology
Male
Mass Screening - methods
Middle Aged
Thyroid Diseases - diagnosis - ultrasonography
Thyroid Function Tests
Thyroid Gland - physiology
Thyrotropin - blood
Abstract
Patients with overt hypothyroidism show decreased echogenicity of the thyroid at ultrasonography (US). The aim of this study was to investigate the association between echogenicity of the thyroid/irregular echo pattern, and thyroid function in the general population, i.e. subjects without overt thyroid disease.
A cross-sectional investigation of 4649 randomly selected adult subjects.
Blood samples were analysed for serum TSH, thyroid hormones and thyroid autoantibodies. US of the thyroid was performed.
Participants with decreased echogenicity (n=379) had a higher mean TSH (1.65 mU/l) compared with subjects with normal echogenicity (1.21 mU/l, P
PubMed ID
16990653 View in PubMed
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Association of serum TSH with high body mass differs between smokers and never-smokers.

https://arctichealth.org/en/permalink/ahliterature147807
Source
J Clin Endocrinol Metab. 2009 Dec;94(12):5023-7
Publication Type
Article
Date
Dec-2009
Author
Bjørn Olav Asvold
Trine Bjøro
Lars J Vatten
Author Affiliation
Department of Public Health, Faculty of Medicine, Norwegian University of Science and Technology, N-7489 Trondheim, Norway. bjorn.o.asvold@ntnu.no
Source
J Clin Endocrinol Metab. 2009 Dec;94(12):5023-7
Date
Dec-2009
Language
English
Publication Type
Article
Keywords
Body mass index
Body Weight - physiology
Female
Humans
Hypothyroidism - blood - physiopathology
Male
Norway - epidemiology
Obesity - blood
Smoking - blood - epidemiology
Thyroid Function Tests
Thyrotropin - blood
Thyroxine - blood
Triiodothyronine - blood
Young Adult
Abstract
Recent studies have suggested that the association of low thyroid function with high body mass is restricted to nonsmokers.
The aim was to study the association of thyroid function with body mass separately for smokers and never-smokers.
We conducted a cross-sectional, population-based study.
We studied 27,097 individuals older than 40 yr of age who were without previously known thyroid disease.
We measured mean body mass index (BMI) and odds ratio for obesity (BMI > or = 30.0 kg/m(2)) according to categories of thyroid function, in women and men, and separately for current smokers and never-smokers. We also studied the association with BMI within the reference range of TSH (0.50-3.5 mU/liter).
TSH within the reference range was positively associated with BMI (P for trend
PubMed ID
19846737 View in PubMed
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Association of thyroid function with estimated glomerular filtration rate in a population-based study: the HUNT study.

https://arctichealth.org/en/permalink/ahliterature140214
Source
Eur J Endocrinol. 2011 Jan;164(1):101-5
Publication Type
Article
Date
Jan-2011
Author
Bjørn Olav Asvold
Trine Bjøro
Lars J Vatten
Author Affiliation
Department of Public Health, Faculty of Medicine, Norwegian University of Science and Technology, PO Box 8905 MTFS, N-7491 Trondheim, Norway. bjorn.o.asvold@ntnu.no
Source
Eur J Endocrinol. 2011 Jan;164(1):101-5
Date
Jan-2011
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Cross-Sectional Studies
Female
Glomerular Filtration Rate
Humans
Hypothyroidism - blood - complications - metabolism
Male
Middle Aged
Norway - epidemiology
Odds Ratio
Renal Insufficiency, Chronic - blood - epidemiology - etiology - metabolism
Risk factors
Thyroid Function Tests
Thyroid Gland - metabolism
Thyrotropin - blood
Abstract
Low thyroid function may be associated with reduced glomerular filtration rate (GFR). We therefore studied the association of thyroid function with estimated GFR (eGFR) in a population-based study.
A cross-sectional, population-based study of 29?480 individuals above 40 years of age, without previously known thyroid disease.
We calculated geometric mean eGFR and odds ratio (OR) of chronic kidney disease (CKD; eGFR
Notes
Erratum In: Eur J Endocrinol. 2011 Feb;164(2):316
PubMed ID
20930062 View in PubMed
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Association of thyroid gland volume, serum insulin-like growth factor-I, and anthropometric variables in euthyroid prepubertal children.

https://arctichealth.org/en/permalink/ahliterature95177
Source
J Clin Endocrinol Metab. 2009 Oct;94(10):4031-5
Publication Type
Article
Date
Oct-2009
Author
Boas Malene
Hegedüs Laszlo
Feldt-Rasmussen Ulla
Skakkebaek Niels E
Hilsted Linda
Main Katharina M
Author Affiliation
University Department of Growth and Reproduction, Rigshospitalet, DK-2100 Copenhagen, Denmark. malene.boas@rh.regionh.dk
Source
J Clin Endocrinol Metab. 2009 Oct;94(10):4031-5
Date
Oct-2009
Language
English
Publication Type
Article
Keywords
Autoantibodies - blood
Biological Markers - blood - metabolism - urine
Body Size
Child
Child Development
Child, Preschool
Denmark
Female
Human Growth Hormone - blood
Humans
Insulin-Like Growth Factor I - metabolism
Iodine - urine
Male
Mothers
Puberty
Questionnaires
Thyroid Function Tests
Thyroid Gland - anatomy & histology - ultrasonography
Thyroid Hormones - blood
Thyrotropin - blood
Abstract
CONTEXT AND OBJECTIVE: Few studies have focused on the interrelation between thyroid size, anthropometric variables, and IGF-I in adults, but such data are lacking for children. We have investigated thyroid gland volume and several hormonal and anthropometric variables in prepubertal children. DESIGN AND PARTICIPANTS: A total of 859 prepubertal euthyroid Danish children aged 4-9 yr underwent a thorough clinical investigation, including anthropometrical measurements and determination of TSH, thyroid hormones, autoantibodies, urinary iodine excretion, and thyroid volume (TV) by ultrasound. Longitudinal growth data from birth were available. RESULTS: TV increased significantly with age (r = 0.487; P
PubMed ID
19602556 View in PubMed
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Association of tobacco smoking with goiter in a low-iodine-intake area.

https://arctichealth.org/en/permalink/ahliterature67387
Source
Arch Intern Med. 2002 Feb 25;162(4):439-43
Publication Type
Article
Date
Feb-25-2002
Author
Nils Knudsen
Inge Bülow
Peter Laurberg
Lars Ovesen
Hans Perrild
Torben Jørgensen
Author Affiliation
Danish Centre for Prevention of Thyroid Diseases (DanThyr), Glostrup University Hospital, Copenhagen, Denmark. nijak@herlevhosp.kbhamt.dk
Source
Arch Intern Med. 2002 Feb 25;162(4):439-43
Date
Feb-25-2002
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Cross-Sectional Studies
Denmark - epidemiology
Female
Goiter - complications - epidemiology - ultrasonography
Humans
Interviews
Iodine - deficiency
Linear Models
Male
Middle Aged
Prevalence
Questionnaires
Research Support, Non-U.S. Gov't
Smoking - adverse effects
Smoking Cessation
Thyroid Function Tests
Abstract
BACKGROUND: Goiter development depends on genetic and environmental factors. The major environmental factor is iodine intake, whereas diverging results have been published concerning the association between smoking and goiter. METHODS: A comparable, cross-sectional study was performed of patients from 2 areas in Denmark with mild and moderate iodine deficiency. A random sample of women and men in selected age groups from the general community was investigated; 4649 subjects participated. Smoking habits were investigated with questionnaires and interviews. Ultrasonography and clinical examination of the thyroid were performed, serum thyroglobulin was measured, and iodine concentration in spot urine samples was analyzed. Data were analyzed in linear models and logistic regression analyses. RESULTS: Serum thyroglobulin level and thyroid volume at ultrasonography were positively associated with smoking habits (P
PubMed ID
11863477 View in PubMed
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[A study of 56-65 years old persons in Mölnlycke. No association between Helicobacter and heart disease or thyroid disorder]

https://arctichealth.org/en/permalink/ahliterature53781
Source
Lakartidningen. 2002 Feb 7;99(6):508-9
Publication Type
Article
Date
Feb-7-2002
Source
Ugeskr Laeger. 1984 Sep 10;146(37):2767-9
Publication Type
Article
Date
Sep-10-1984

115 records – page 1 of 12.