Between 1979 and 1984 11 cases of fulminant hepatitis were seen at the Department of Infectious Diseases in Lund, Sweden. Four cases were associated with hepatitis B virus (HBV) infection. Besides, all 4 patients had serological evidence of delta infection. Two were considered to be simultaneous HBV and delta agent infections, the other 2 were found to be delta superinfections in chronic HBsAg carriers. All 4 patients were intravenous drug addicts. The other 7 cases of fulminant hepatitis had no serological evidence of neither hepatitis A nor B virus infections and none of them were intravenous drug addicts.
HIV infection has spread rapidly among intravenous drug addicts. In Denmark, the infection is limited to Copenhagen where the prevalence is 10-25%. Improved supervision of this partial epidemic is essential. The measures instituted to limit spread of infection are still inadequate.