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1633 records – page 1 of 164.

2-DE protein expression in endometrial carcinoma.

https://arctichealth.org/en/permalink/ahliterature80911
Source
Acta Oncol. 2006;45(6):685-94
Publication Type
Article
Date
2006
Author
Caroline, L
Johanna, L
Susanne, B
Uwe, R
Kjell, S
Karolina, B
Bo, F
Britta, N
Gert, A
Author Affiliation
Department of Gynaecologic Oncology, Radiumhemmet, Institute of Oncology and Pathology, Karolinska University Hospital and Institute, Stockholm, Sweden. caroline.lundgren@karolinska.se
Source
Acta Oncol. 2006;45(6):685-94
Date
2006
Language
English
Publication Type
Article
Keywords
Carcinoma - metabolism
Cluster analysis
Electrophoresis, Gel, Two-Dimensional
Endometrial Neoplasms - metabolism - pathology
Female
Gene Expression
Histocytochemistry
Humans
Neoplasm Proteins - metabolism
Ploidies
Statistics, nonparametric
Sweden
Abstract
The objective of this study was to explore the protein expression pattern in normal endometrial mucosa (n = 5) and endometrial carcinoma (n = 15) of low (diploid) and high (aneuploid) malignancy potential by two-dimensional gel electrophoresis (2-DE). The specimens were evaluated for histopathologic subtype, stage and grade in relation to DNA ploidy. A match-set consisting of five samples from normal endometrium, eight diploid and seven aneuploid tumours was created. All the diploid and three of the aneuploid tumours were of endometrioid subtype, while the remaining four were of uterine seropapillary type. There were 192 protein spots differentiating diploid tumours from normal endometrium and 238 protein spots were separating aneuploid tumours from normal endometrium (p
PubMed ID
16938811 View in PubMed
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2-year clinical performance of a fluoride-containing fissure sealant in young schoolchildren at caries risk.

https://arctichealth.org/en/permalink/ahliterature34233
Source
Am J Dent. 1997 Jun;10(3):115-9
Publication Type
Article
Date
Jun-1997
Author
A. Carlsson
M. Petersson
S. Twetman
Author Affiliation
Public Dental Clinic, Vallås, Sweden.
Source
Am J Dent. 1997 Jun;10(3):115-9
Date
Jun-1997
Language
English
Publication Type
Article
Keywords
Analysis of Variance
Cariostatic Agents - analysis - therapeutic use
Chi-Square Distribution
Child
Colony Count, Microbial
Composite Resins - chemistry - therapeutic use
Dental Caries - epidemiology - prevention & control
Dental Plaque - microbiology
Fluorides - analysis - pharmacology - therapeutic use
Humans
Lactobacillus - drug effects - isolation & purification
Pit and Fissure Sealants - therapeutic use
Prevalence
Risk assessment
Saliva - chemistry - microbiology
Statistics, nonparametric
Streptococcus mutans - drug effects - isolation & purification
Sweden - epidemiology
Abstract
PURPOSE: To evaluate the clinical performance of Helioseal-F, a fluoride-containing fissure sealant, in school children at caries risk. MATERIALS AND METHODS: A caries risk assessment based on past caries experience, saliva microbial tests, buffer capacity and frequency of sugar intake was carried out in 204 healthy children, 6-7 years of age. Children exhibiting one or more risk factors were considered at caries risk (n = 121) and their permanent molars were sealed with a fluoride-containing fissure sealant, thus forming a fissure sealant group (FSG). The remaining 83 children with low caries risk received no fissure sealants and constituted a reference group (RG). Both groups were followed for 2 years. From 15 children of both groups, unstimulated whole saliva was collected 1 month after sealant placement in order to determine fluoride levels. In another 20 children, a split-mouth study design was utilized to compare the colonization of mutans streptococci adjacent to and on F-containing sealants and conventional controls. The sealants were placed by dental hygienists according to the manufacturers' instructions. RESULTS: A total of 431 fissure sealants were placed at baseline. Complete retention was found in 76.6% during the study period while 22.0% were partially lost. Six sealants (1.4%) were completely lost. The enamel caries incidence was 45% lower (P
PubMed ID
9545884 View in PubMed
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10-year results of a new low-monomer cement: follow-up of a randomized RSA study.

https://arctichealth.org/en/permalink/ahliterature119286
Source
Acta Orthop. 2012 Dec;83(6):604-8
Publication Type
Article
Date
Dec-2012
Author
Per Söderlund
Jon Dahl
Stephan Röhrl
Bo Nivbrant
Kjell G Nilsson
Author Affiliation
Institution of Surgery and Perioperative Sciences and Department of Orthopedics, Umeå University, Umeå, Sweden. per.soderlund@orthop.umu.se
Source
Acta Orthop. 2012 Dec;83(6):604-8
Date
Dec-2012
Language
English
Publication Type
Article
Keywords
Aged
Arthroplasty, Replacement, Hip - adverse effects - methods
Bone Cements - chemistry - therapeutic use
Confidence Intervals
Female
Follow-Up Studies
Hip Prosthesis
Humans
Male
Middle Aged
Prospective Studies
Prosthesis Design
Prosthesis Failure
Range of Motion, Articular - physiology
Risk assessment
Statistics, nonparametric
Sweden
Time Factors
Titanium
Treatment Outcome
Abstract
The properties and performance of a new low-monomer cement were examined in this prospective randomized, controlled RSA study. 5-year data have already been published, showing no statistically significant differences compared to controls. In the present paper we present the 10-year results.
44 patients were originally randomized to receive total hip replacement with a Lubinus SPII titanium-aluminum-vanadium stem cemented either with the new Cemex Rx bone cement or with control bone cement, Palacos R. Patients were examined using RSA, Harris hip score, and conventional radiographs.
At 10 years, 33 hips could be evaluated clinically and 30 hips could be evaluated with RSA (16 Cemex and 14 Palacos). 9 patients had died and 4 patients were too old or infirm to be investigated. Except for 1 hip that was revised for infection after less than 5 years, no further hips were revised before the 10-year follow-up. There were no statistically significant clinical differences between the groups. The Cemex cement had magnitudes of migration similar to or sometimes lower than those of Palacos cement. In both groups, most hips showed extensive radiolucent lines, probably due to the use of titanium alloy stems.
At 10 years, the Cemex bone cement tested performed just as well as the control (Palacos bone cement).
Notes
Cites: Acta Orthop Scand. 2001 Dec;72(6):572-8411817871
Cites: J Bone Joint Surg Br. 2004 Sep;86(7):974-815446521
Cites: Acta Orthop Scand Suppl. 1986;221:1-403468743
Cites: Br Med J (Clin Res Ed). 1988 May 21;296(6634):1454-63132290
Cites: J Biomed Mater Res. 1993 May;27(5):565-748314809
Cites: J Arthroplasty. 2000 Aug;15(5):570-510959994
Cites: Acta Orthop Scand. 1994 Feb;65(1):20-38154277
Cites: J Appl Biomater. 1995 Spring;6(1):75-837703541
Cites: J Bone Joint Surg Am. 1996 Mar;78(3):325-308613438
Cites: J Bone Joint Surg Br. 1996 Sep;78(5):802-88836075
Cites: Acta Orthop. 2008 Dec;79(6):826-3119085502
Cites: Clin Orthop Relat Res. 1993 Oct;(295):239-458403655
PubMed ID
23116438 View in PubMed
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A 15-month evaluation of the effects of repeated subgingival minocycline in chronic adult periodontitis.

https://arctichealth.org/en/permalink/ahliterature201582
Source
J Periodontol. 1999 Jun;70(6):657-67
Publication Type
Article
Date
Jun-1999
Author
D. van Steenberghe
B. Rosling
P O Söder
R G Landry
U. van der Velden
M F Timmerman
E F McCarthy
G. Vandenhoven
C. Wouters
M. Wilson
J. Matthews
H N Newman
Author Affiliation
Catholic University, Leuven, Belgium.
Source
J Periodontol. 1999 Jun;70(6):657-67
Date
Jun-1999
Language
English
Publication Type
Article
Keywords
Adult
Aggregatibacter actinomycetemcomitans - drug effects
Analysis of Variance
Anti-Bacterial Agents - administration & dosage
Campylobacter - drug effects
Canada
Chronic Disease
Colony Count, Microbial
Dental Plaque Index
Dental Scaling
Double-Blind Method
Eikenella corrodens - drug effects
Europe
Female
Fusobacterium nucleatum - drug effects
Humans
Longitudinal Studies
Male
Middle Aged
Minocycline - administration & dosage
Ointments
Periodontal Index
Periodontal Pocket - drug therapy - microbiology
Periodontitis - drug therapy - microbiology
Porphyromonas gingivalis - drug effects
Prevotella intermedia - drug effects
Statistics, nonparametric
Treatment Outcome
Treponema - drug effects
Abstract
A double-blind, randomized, parallel, comparative study was designed to evaluate the long-term safety and efficacy of subgingivally administered minocycline ointment versus a vehicle control.
One hundred four patients (104) with moderate to severe adult periodontitis (34 to 64 years of age; mean 46 years) were enrolled in the study. Following scaling and root planing, patients were randomized to receive either 2% minocycline ointment or a matched vehicle control. Study medication was administered directly into the periodontal pocket with a specially designed, graduated, disposable applicator at baseline; week 2; and at months 1, 3, 6, 9, and 12. Scaling and root planing was repeated at months 6 and 12. Standard clinical variables (including probing depth and attachment level) were evaluated at baseline and at months 1, 3, 6, 9, 12, and 15. Microbiological sampling using DNA probes was done at baseline; at week 2; and at months 1, 3, 6, 9, 12, and 15.
Both treatment groups showed significant and clinically relevant reductions in the numbers of each of the 7 microorganisms measured during the entire 15-month study period. When differences were detected, sites treated with minocycline ointment always produced statistically significantly greater reductions than sites which received the vehicle control. For initial pockets > or =5 mm, a mean reduction in probing depth of 1.9 mm was seen in the test sites, versus 1.2 mm in the control sites. Sites with a baseline probing depth > or =7 mm and bleeding index >2 showed an average of 2.5 mm reduction with minocycline versus 1.5 mm with the vehicle. Gains in attachment (0.9 mm and 1.1 mm) were observed in minocycline-treated sites, with baseline probing depth > or =5 mm and > or =7 mm, respectively, compared with 0.5 mm and 0.7 mm gain at control sites. Subgingival administration of minocycline ointment was well tolerated.
Overall, the results demonstrate that repeated subgingival administration of minocycline ointment in the treatment of adult periodontitis is safe and leads to significant adjunctive improvement after subgingival instrumentation in both clinical and microbiologic variables over a 15-month period.
PubMed ID
10397521 View in PubMed
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A 15-yr longitudinal study of xerostomia in a Swedish population of 50-yr-old subjects.

https://arctichealth.org/en/permalink/ahliterature90130
Source
Eur J Oral Sci. 2009 Feb;117(1):13-9
Publication Type
Article
Date
Feb-2009
Author
Johansson Ann-Katrin
Johansson Anders
Unell Lennart
Ekbäck Gunnar
Ordell Sven
Carlsson Gunnar E
Author Affiliation
Department of Clinical Dentistry-Cariology, Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway. Ann-Katrin.Johansson@iko.uib.no
Source
Eur J Oral Sci. 2009 Feb;117(1):13-9
Date
Feb-2009
Language
English
Publication Type
Article
Keywords
Age Factors
Aged
Circadian Rhythm
Cross-Sectional Studies
Female
Health status
Humans
Longitudinal Studies
Male
Middle Aged
Sex Factors
Smoking - epidemiology
Statistics, nonparametric
Sweden - epidemiology
Xerostomia - epidemiology
Abstract
The aim of this study was to determine the changes in prevalence of xerostomia in subjects from 50 to 65 yr of age. Questionnaires were sent to all subjects who were born in 1942 and were living in two Swedish counties in 1992, 1997, 2002, and 2007. The analyses focused on those who answered the questionnaires both in 1992 and in 2007. The response rate was 71.4% (n = 6,346) in 1992 and 73.1% (n = 6,078) in 2007. Of those who answered the questionnaire in 1992, 74.3% (n = 4,714) also responded in 2007. There was an almost linear increase in the prevalence of xerostomia at the four study time-points (i.e. when the subjects were 50, 55, 60, and 65 yr of age). Xerostomia was more prevalent at night than during the day. The pooled prevalence of night-time and daytime xerostomia was 6% at 50 yr of age and 15% at 65 yr of age, and it was higher in women than in men on both occasions. Logistic regression analyses showed that impaired health and smoking were significantly associated with daytime xerostomia but not with night-time xerostomia. Despite the increase in prevalence of xerostomia from 50 to 65 yr of age, there was considerable variation during the observation period. The incidence rate was 13% (507/4,015) and the disappearance rate was 42% (104/250) (dichotomized answers).
PubMed ID
19196313 View in PubMed
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A 24-week dietary and physical activity lifestyle intervention reduces hepatic insulin resistance in the obese with chronic hepatitis C.

https://arctichealth.org/en/permalink/ahliterature117638
Source
Liver Int. 2013 Mar;33(3):410-9
Publication Type
Article
Date
Mar-2013
Author
Venessa Pattullo
Andres Duarte-Rojo
Wael Soliman
Florencia Vargas-Vorackova
Sanjeev Sockalingam
Ivan G Fantus
Johane Allard
Jenny Heathcote
Author Affiliation
Department of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada.
Source
Liver Int. 2013 Mar;33(3):410-9
Date
Mar-2013
Language
English
Publication Type
Article
Keywords
Anthropometry
Basal Metabolism
Blood pressure
Body mass index
Exercise Therapy - methods
Female
Hepatitis C, Chronic - complications - pathology
Humans
Insulin Resistance - physiology
Male
Middle Aged
Motor Activity - physiology
Obesity - complications - diet therapy - therapy
Ontario
Prospective Studies
Statistics, nonparametric
Abstract
Obesity- and virus-mediated insulin resistance (IR) are associated with adverse hepatic and metabolic outcomes in chronic hepatitis C (CHC). This study evaluates the tolerability and effects of a dietary and physical activity (PA) intervention in obese patients with insulin-resistant CHC.
Obese patients (body mass index, BMI =30 kg/m(2) ) with CHC were recruited prospectively. Non-diabetic patients with IR (homeostasis model assessment of IR, HOMA-IR >2.0) proceeded to a 24-week lifestyle intervention comprising pedometer monitored increase in PA (=10 000 steps/day) and an individualised dietary plan.
Ten non-cirrhotic and six cirrhotic patients [age 52 ± 8.5 years, BMI 35.9 (31.46-38.21)kg/m(2) ] were recruited, of whom all 16 (100%) completed the 24-week protocol. Increase in PA from 6853 (2440-9533) to 10 697 (7959-13566) steps/day (P = 0.001) and reduction in caloric intake from 2263 (1805.4-2697.0) to 1281 (1099.5-1856.3) kcal/day (equivalent to reduction of median 33% (25.3-49.8%), P
PubMed ID
23278982 View in PubMed
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Abductor Muscle Function and Trochanteric Tenderness After Hemiarthroplasty for Femoral Neck Fracture.

https://arctichealth.org/en/permalink/ahliterature281385
Source
J Orthop Trauma. 2016 Jun;30(6):e194-200
Publication Type
Article
Date
Jun-2016
Author
Arkan S Sayed-Noor
Aleksandra Hanas
Olof G Sköldenberg
Sebastian S Mukka
Source
J Orthop Trauma. 2016 Jun;30(6):e194-200
Date
Jun-2016
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Cohort Studies
Female
Femoral Neck Fractures - diagnosis - surgery
Follow-Up Studies
Hemiarthroplasty - adverse effects - methods
Hospitals, Teaching
Humans
Injury Severity Score
Linear Models
Logistic Models
Male
Middle Aged
Pain Measurement
Pain, Postoperative - diagnosis - therapy
Prospective Studies
Psoas Muscles - physiopathology
Risk assessment
Statistics, nonparametric
Sweden
Treatment Outcome
Abstract
To compare the abductor muscle function and trochanteric tenderness in patients operated with hemiarthroplasty using the direct lateral (DL) or posterolateral (PL) approach for displaced femoral neck fracture.
Prospective cohort study.
A secondary teaching hospital.
We enrolled 183 hips operated with hemiarthroplasty for displaced femoral neck fracture using the DL or PL approach.
Preoperatively, we evaluated the Harris hip score (HHS) and European Quality of Life-5 Dimensions (EQ-5D). At 1 year postoperatively, lucid patients were clinically examined to evaluate the Trendelenburg sign, abductor muscle strength with a dynamometer, and trochanteric tenderness with an electronic algometer. The 1-year HHS and EQ-5D were documented.
The primary outcome was the incidence of postoperative Trendelenburg sign, whereas the secondary outcomes included patients' reported limp, abductor muscle strength, trochanteric tenderness, HHS, and EQ-5D.
There were 48 patients (24 in the DL group and 24 in the PL group) who attended the 1-year clinical follow-up. The 2 groups were comparable (P > 0.05). The DL group showed a higher incidence of the Trendelenburg sign (9/24 vs. 1/24, P = 0.02) and limp (12/24 vs. 2/24, P = 0.004). Further analysis with logistic regression showed the surgical approach to be the only factor that resulted in the increment. No differences regarding HHS, EQ-5D, abductor muscle strength, algometer pressure pain threshold, and radiologic measurements were found (P > 0.05).
The incidence of the Trendelenburg sign and limp were significantly higher in the DL approach although this seemed not to influence abductor muscle strength or the incidence of trochanteric tenderness or compromise the clinical outcome.
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
PubMed ID
27206260 View in PubMed
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Ability for self-care among home dwelling elderly people in a health district in Sweden.

https://arctichealth.org/en/permalink/ahliterature72190
Source
Int J Nurs Stud. 2000 Aug;37(4):361-8
Publication Type
Article
Date
Aug-2000
Author
O. Söderhamn
C. Lindencrona
A. Ek
Author Affiliation
Vänersborg University College of Health Sciences, P.O. Box 236, SE-462 23, Vänersborg, Sweden.
Source
Int J Nurs Stud. 2000 Aug;37(4):361-8
Date
Aug-2000
Language
English
Publication Type
Article
Keywords
Activities of Daily Living
Aged
Aged, 80 and over
Analysis of Variance
Cohort Studies
Female
Humans
Male
Regression Analysis
Research Support, Non-U.S. Gov't
Self Care
Statistics, nonparametric
Sweden
Abstract
The aim of this study was to describe the ability for self-care among home dwelling elderly in the community in a health district in western Sweden. Two self-report instruments plus a number of self-care related questions were distributed by mail to an age stratified random sample and finally completed by a total of 125 subjects. Bivariate and multivariate statistical methods were used in the analyses. The results showed that self-care ability and self-care agency decreased for respondents 75+ years of age. Self-care ability was predicted by three productive means for self-care and four risk factors.
PubMed ID
10760543 View in PubMed
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The ability of Corah's Dental Anxiety Scale and Spielberger's State Anxiety Inventory to distinguish between fearful and regular Norwegian dental patients.

https://arctichealth.org/en/permalink/ahliterature205093
Source
Acta Odontol Scand. 1998 Apr;56(2):105-9
Publication Type
Article
Date
Apr-1998
Author
G. Kvale
E. Berg
M. Raadal
Author Affiliation
Department of Clinical Psychology, University of Bergen, Norway.
Source
Acta Odontol Scand. 1998 Apr;56(2):105-9
Date
Apr-1998
Language
English
Publication Type
Article
Keywords
Adult
Analysis of Variance
Dental Anxiety - diagnosis
Discriminant Analysis
Female
Humans
Male
Manifest Anxiety Scale
Norway
Psychometrics - methods
Regression Analysis
Reproducibility of Results
Sex Factors
Statistics, nonparametric
Abstract
The purpose of this study was to test the ability of Corah's Dental Anxiety Scale (DAS) and Spielberger's State Anxiety Inventory (STAI-S) to distinguish between fearful (n = 145) and regularly attending (n = 156) Norwegian dental patients. The reliability of both instruments was high (Cronbach's alpha indices > 0.95). With DAS, 90% of the fearful patients and 85% of the reference patients were correctly assigned to their appropriate group. Thus it may be concluded that, when used on a Norwegian population, DAS is a valid instrument for distinguishing fearful patients from those regularly attending dental treatment. The corresponding figures for STAI-S were 80% for the fearful patients and 79% for the reference patients. Although not developed specifically for this purpose, this instrument may therefore still validly be used to distinguish between the groups. The correlation between the instruments was 0.76, indicating that to some extent they measure the same phenomenon.
PubMed ID
9669462 View in PubMed
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The ability of hand digital X-ray radiogrammetry to identify middle-aged and elderly women with reduced bone density, as assessed by femoral neck dual-energy X-ray absorptiometry.

https://arctichealth.org/en/permalink/ahliterature139761
Source
J Clin Densitom. 2010 Oct-Dec;13(4):418-25
Publication Type
Article
Author
Alvilde Dhainaut
Gudrun E Rohde
Unni Syversen
Villy Johnsen
Glenn Haugeberg
Author Affiliation
Department of Neuroscience, Rheumatology Division, INM Norwegian University of Science and Technology, Trondheim, Norway. alvilde.dhainaut@ntnu.no
Source
J Clin Densitom. 2010 Oct-Dec;13(4):418-25
Language
English
Publication Type
Article
Keywords
Absorptiometry, Photon - instrumentation
Aged
Area Under Curve
Bone Density
Case-Control Studies
Female
Femur Neck - radiography
Humans
Middle Aged
Norway - epidemiology
Osteoporosis - epidemiology - radiography
Quality of Life
Radius Fractures - epidemiology
Risk assessment
Statistics, nonparametric
Abstract
In this study, we evaluate the ability of digitized digital X-ray radiogrammetry (DXR) bone mineral density (BMD) to identify women with reduced BMD at femoral neck, assessed by dual-energy X-ray absorptiometry (DXA). The study population contained women with recent low-energy distal radius fracture and women recruited from the general population, all aged 50 yr or older. The correlation between hand BMD and femoral neck BMD was r=0.65 (p
PubMed ID
21029976 View in PubMed
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1633 records – page 1 of 164.