Pulse therapy with methylprednisolone (Solu-Medrol, Upjohn), 1000 mg daily over three successive days, was administered to patients in two randomized groups of 14 patients in each (23 patients with systemic lupus erythematosus, 5 with rheumatoid arthritis). In one of the groups the drug was taken per os, the other received it intravenously. There was no significant difference between the two groups in terms of clinical effectiveness and incidence of side effects However, the time-related course of such indices as erythrocyte sedimentation rate, the level of leukocytes, of total protein, urea, the blood antioxidant potential, permeability of erythrocytic membranes and capillary and tissue barrier proteinuria as well as the content of immune complexes in the arterial and venous blood was more striking with per os intake. Of the 14 patients, 11 demonstrated short-continued asymptomatic 35% rise in the activity of alaninaminotransferase.
An active remote radiation thermometry was used in the diagnosis and differential diagnosis of ovarian tumours by determining the heat flow from the area of projection of the ovaries and control background. Overall fourty three patients with ovarian tumours were examined by this method. Significance of the results secured was verified during the histological technique-aided operation. The authors have come to the conclusion that remote thermometry involving loading tests is a simple supplementary method of investigation that is helpful in diagnosing of both benign and malignant ovarian tumours.
A questionnaire survey was undertaken in those patients (n = 105) with freshly detected pulmonary tuberculosis who had refused to be treated with antituberculous therapy. The patients' reasons for refusing the above therapy was that they are not in the money to buy medicines (42.86%) and they have a distrust of existing therapies commonly applied in dealing with the medical problem under consideration (30.48%), as evidenced by the questionnaires analysis performed.
A comparative analysis has been carried out of indices for health status in 137,072 persons who took part in the elimination of the aftermath of the Chernobyl accident, using records of the National Register of Ukraine. The above-mentioned indices were for time-related general morbidity, mortality, disability during the period of 1988-1996. There has been revealed yearly increase in morbidity rates in all classes of diseases, in particular those of the circulatory system, nervous system, and sense organs, digestive, and respiratory systems. High morbidity rates are recordable with respect to that class of diseases afflicting the endocrine system, blood, and hemopoietic organs, neoplasms including malignant tumours. The disability rates tended to increase above average statistical ones for Ukraine.
On completing the main course we used regular hypoxic training to maintain an effect of sustenal regimen. The studies were made in young persons divided into three groups: control group, a group undergoing training according to standard regimen, and a group of sustenal regimen of training. Training under conditions of artificial mountain air improves physical and mental performance, psychoemotional state. Sustenal regimen of training is superior to standard regimen. Sustenal regimen of hypoxic training is to be employed in military, space, sports, and clinical medicine, as well as in case of a possible influence on the human body of stressogenic factors.
Chronic glomerulonephritis (ChGN) is a grave poorly controlled disease for which no efficient method of pathogenetic therapy is available. In looking for efficient methods of treatment plants were of traditional (folk) medicine. The present investigation involves an approach based on the concepts of informational content of complicated prescriptions which form the basis of traditional medicine. Methods have been worked out of informational screening of structure of composite multicomponent herbal remedies, on the basis of the information theory using statistical methods. Computer the analysis has been performed of 176 phytotherapeutic formulae for the treatment of ChGN, based on the folk medicine experience. Phytocompositions have been selected to be used for a target-oriented action on human organism in ChGN, being characterized by duplication of components of unidirectional action. Herbs plants were singled out, incompatible in the treatment of ChGN.
A non-loading pneumocalorimetric mode of quantitative assessment of physical performance (PP) has been developed in a series of 25 essentially healthy subjects. Based on the correlation-and-regression analysis a formula for PP was found out to be PP = 59.9 x MCC + 33, were MCC is maximum caloric capacity. PP quantitative assessment was proved to be effective in patients presenting with cardiopulmonary problems.
Based on the parasitologic evaluation of 3926 individuals in different climatic and geographic areas of Ukraine it has been ascertained that levels of affection of people with opisthorchiasis depend upon natural as well as social conditions, age of the examinees (but not sex of those infected), remoteness from riverbeds. It has been shown that high levels of contamination of soil with eggs of helminths and cysts of intestinal protozoans in those foci of opisthorchiasis having very high incidence rates of this invasion make for formation in the population of multicomponent intestinal parasite cenoses.