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570 records – page 1 of 57.

3,520 medication errors evaluated to assess the potential for IT-based decision support.

https://arctichealth.org/en/permalink/ahliterature133611
Source
Stud Health Technol Inform. 2011;166:31-7
Publication Type
Article
Date
2011
Author
Kristine Binzer
Annemarie Hellebek
Author Affiliation
Unit for Patient Safety, Capital Region of Denmark.
Source
Stud Health Technol Inform. 2011;166:31-7
Date
2011
Language
English
Publication Type
Article
Keywords
Decision Support Systems, Clinical - organization & administration
Denmark
Humans
Information Systems - organization & administration
Medication Errors - classification - statistics & numerical data
Software Design
Abstract
We have previously studied system failures involved in medication errors using a limited number of root cause analyses as source. The aim of this study was to describe a larger number of medication errors with respect to harm, involved medicines and involved system problems - thus providing information for the development of IT-based decision support. We evaluated 3,520 medication error reports derived from 12 months of consecutive reporting from 13 hospitals in the Capital Region of Denmark. We found 0.65% errors with serious harm and 16% with moderate harm. A small number of medicines were involved in the majority of the errors. The problems in the medication error process were heterogeneous. Some were related to specific medicines and others were related to the computerized order entry system. Accordingly decision support targeted at specific medicines and improved IT systems are part of the continuing work to reduce the frequency of medication errors.
PubMed ID
21685608 View in PubMed
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[6-year trial of a program for predicting the potential occurrence of myocardial infarct].

https://arctichealth.org/en/permalink/ahliterature234833
Source
Kardiologiia. 1987 Sep;27(9):43-7
Publication Type
Article
Date
Sep-1987
Author
E Sh Khalfen
I L Shvarts
Source
Kardiologiia. 1987 Sep;27(9):43-7
Date
Sep-1987
Language
Russian
Publication Type
Article
Keywords
Adult
Age Factors
Aged
Female
Humans
Male
Middle Aged
Myocardial Infarction - epidemiology - etiology
Prognosis
Risk factors
Russia
Sex Factors
Software
Urban Population
Abstract
A six-year prospective study of 3775 individuals, first examined in 1978, using an original mathematical program of myocardial infarction risk prognosis, is reported. The program is based on an integral assessment of 19 risk factors, each having 4 degrees of severity. The subjects were allocated to one of 3 groups, depending on the prognostic risk score. In the low coronary risk group (2068 people), there was 1 (0.048%) myocardial infarction over 6 years. There were 12 (0.76%) infarctions in the medium risk group (1569 people), and 62 (44.92%) infarctions in the high risk group (138 people). Therefore, the program is capable of identifying a limited (about 4%) population that is going to develop 80% of all myocardial infarctions within the next 5 or 6 years.
PubMed ID
2961917 View in PubMed
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Source
Neuromodulation. 2013 Nov-Dec;16(6):506-13; discussion 513
Publication Type
Article
Author
Kaare Meier
Lone Nikolajsen
Morten Flink
Ronnie Simonsen
Ioanna Milidou
Troels Staehelin Jensen
Jens Christian Sørensen
Author Affiliation
Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark; Department of Neurosurgery, Aarhus University Hospital, Aarhus, Denmark; Department of Anesthesiology, Aarhus University Hospital, Aarhus, Denmark; ITmedico, Aarhus, Denmark; Perinatal Epidemiology Research Unit, Aarhus University Hospital, Aarhus, Denmark; and Department of Neurology, Aarhus University Hospital, Aarhus, Denmark.
Source
Neuromodulation. 2013 Nov-Dec;16(6):506-13; discussion 513
Language
English
Publication Type
Article
Keywords
Analgesics - therapeutic use
Chronic Pain - therapy
Computer Security
Databases, Factual
Denmark
Employment
Humans
Internet
Neuralgia - drug therapy - therapy
Neurosurgical Procedures - adverse effects
Pain Measurement
Quality of Life
Questionnaires
Software
Spinal Cord Stimulation - adverse effects
Treatment Outcome
Abstract
?? Spinal cord stimulation (SCS) is increasingly gaining widespread use as a treatment for chronic pain. A widely used electronic registry could play a pivotal role in improving this complex and cost-?intensive treatment. We aimed to construct a comprehensive, universally available data base for SCS.
?? The design considerations behind a new online data base for SCS are presented; basic structure, technical issues, research applications, and future perspectives are described.
?? The Aarhus Neuromodulation Database covers core SCS treatment parameters, including procedure-?related details and complications, and features recording of key success parameters such as pain intensity, work status, and quality of life. It combines easy access to patient information with exhaustive data extraction options, and it can readily be adapted and expanded to suit different needs, including other neuromodulation treatment modalities.
?? We believe that the data base described in this article offers a powerful and versatile data collection tool suited for both clinicians and researchers in the field. The basic data base structure is immediately available on a no?-cost basis, and we invite our colleagues to make use of the data base as part of the efforts to further the field of neuromodulation.
PubMed ID
22882331 View in PubMed
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Acceptability of extrusion cooked cereal/legume weaning food supplements to Ghanaian mothers.

https://arctichealth.org/en/permalink/ahliterature195584
Source
Int J Food Sci Nutr. 2001 Jan;52(1):83-90
Publication Type
Article
Date
Jan-2001
Author
Y. Mensa-Wilmot
R D Phillips
S. Sefa-Dedeh
Author Affiliation
Center for Food Safety and Quality Enhancement-Department of Food Science and Technology, University of Georgia, Agricultural Experiment Station, Griffin, GA 30223-1797, USA.
Source
Int J Food Sci Nutr. 2001 Jan;52(1):83-90
Date
Jan-2001
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Analysis of Variance
Cereals
Chi-Square Distribution
Consumer Satisfaction
Dietary Supplements
Fabaceae
Female
Focus Groups
Food Handling
Humans
Infant
Middle Aged
Mothers
Plants, Medicinal
Software
Weaning
Abstract
Six cereal/legume mixtures were developed with the aid of computer-assisted optimization software from cereal and legume staples indigenous to the West African sub-region. The mixtures had 45-50% maize, 35-40% decorticated cowpeas and either blanched peanuts or decorticated soybeans as a source of lipid and complementary amino acids. Three processing schemes involving roasting, amylase digestion and extrusion cooking were employed. The proportion of ingredients in each cereal/legume blend was based on meeting the nutrient requirement of the 0.5-0.9-year-old infant and cost considerations. Nutrient composition of the blends (proximate, amino acid, mineral and vitamin composition) indicated that these formulations were adequate nutritionally as weaning supplements (Mensa-Wilmot et al, 2000a,2000b). These formulations were evaluated by mothers of weanling children based on their preferences with respect to color, flavor, texture and willingness to purchase the product assessed. A total of 133 one-on-one interviews and 23 group discussions were conducted (involving 6-12 respondents) with selected Ghanaian women. The mothers found the convenience of a weaning food made from local staples that could be processed on village/market scale very attractive.
PubMed ID
11225182 View in PubMed
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The accuracy of quantitative parameters in (99m) Tc-MAG3 dynamic renography: a national audit based on virtual image data.

https://arctichealth.org/en/permalink/ahliterature277742
Source
Clin Physiol Funct Imaging. 2016 Mar;36(2):146-54
Publication Type
Article
Date
Mar-2016
Author
Gustav Brolin
Lars Edenbrandt
Göran Granerus
Anna Olsson
David Afzelius
Agneta Gustafsson
Cathrine Jonsson
Jessica Hagerman
Lena Johansson
Katrine Riklund
Michael Ljungberg
Source
Clin Physiol Funct Imaging. 2016 Mar;36(2):146-54
Date
Mar-2016
Language
English
Publication Type
Article
Keywords
Computer simulation
Feasibility Studies
Female
Gamma Cameras
Humans
Image Interpretation, Computer-Assisted
Kidney - physiopathology - radionuclide imaging
Kidney Diseases - physiopathology - radionuclide imaging
Male
Monte Carlo Method
Observer Variation
Phantoms, Imaging
Predictive value of tests
Radioisotope Renography - instrumentation - methods - standards
Radiopharmaceuticals - administration & dosage
Reproducibility of Results
Software
Sweden
Technetium Tc 99m Mertiatide - administration & dosage
Abstract
Assessment of image analysis methods and computer software used in (99m) Tc-MAG3 dynamic renography is important to ensure reliable study results and ultimately the best possible care for patients. In this work, we present a national multicentre study of the quantification accuracy in (99m) Tc-MAG3 renography, utilizing virtual dynamic scintigraphic data obtained by Monte Carlo-simulated scintillation camera imaging of digital phantoms with time-varying activity distributions. Three digital phantom studies were distributed to the participating departments, and quantitative evaluation was performed with standard clinical software according to local routines. The differential renal function (DRF) and time to maximum renal activity (Tmax ) were reported by 21 of the 28 Swedish departments performing (99m) Tc-MAG3 studies as of 2012. The reported DRF estimates showed a significantly lower precision for the phantom with impaired renal uptake than for the phantom with normal uptake. The Tmax estimates showed a similar trend, but the difference was only significant for the right kidney. There was a significant bias in the measured DRF for all phantoms caused by different positions of the left and right kidney in the anterior-posterior direction. In conclusion, this study shows that virtual scintigraphic studies are applicable for quality assurance and that there is a considerable uncertainty associated with standard quantitative parameters in dynamic (99m) Tc-MAG3 renography, especially for patients with impaired renal function.
PubMed ID
25348641 View in PubMed
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Accurate Non-parametric Estimation of Recent Effective Population Size from Segments of Identity by Descent.

https://arctichealth.org/en/permalink/ahliterature268195
Source
Am J Hum Genet. 2015 Sep 3;97(3):404-18
Publication Type
Article
Date
Sep-3-2015
Author
Sharon R Browning
Brian L Browning
Source
Am J Hum Genet. 2015 Sep 3;97(3):404-18
Date
Sep-3-2015
Language
English
Publication Type
Article
Keywords
Chromosomes - genetics
Computer simulation
Finland
Genetics, Population - methods
Great Britain
Humans
Linkage Disequilibrium
Models, Genetic
Pedigree
Polymorphism, Single Nucleotide - genetics
Population Density
Software
Abstract
Existing methods for estimating historical effective population size from genetic data have been unable to accurately estimate effective population size during the most recent past. We present a non-parametric method for accurately estimating recent effective population size by using inferred long segments of identity by descent (IBD). We found that inferred segments of IBD contain information about effective population size from around 4 generations to around 50 generations ago for SNP array data and to over 200 generations ago for sequence data. In human populations that we examined, the estimates of effective size were approximately one-third of the census size. We estimate the effective population size of European-ancestry individuals in the UK four generations ago to be eight million and the effective population size of Finland four generations ago to be 0.7 million. Our method is implemented in the open-source IBDNe software package.
Notes
Cites: Genetics. 1971 Aug;68(4):581-975166069
Cites: Proc Biol Sci. 2013 Oct 7;280(1768):2013133923926150
Cites: Am J Hum Genet. 2013 Nov 7;93(5):840-5124207118
Cites: Mol Biol Evol. 2014 Mar;31(3):723-3524288159
Cites: Nat Genet. 2014 Aug;46(8):919-2524952747
Cites: Am J Hum Genet. 2011 Feb 11;88(2):173-8221310274
Cites: Nature. 2011 Jul 28;475(7357):493-621753753
Cites: Nat Genet. 2012 Mar;44(3):328-3322306652
Cites: Science. 2012 May 11;336(6082):740-322582263
Cites: PLoS One. 2012;7(7):e3755822911679
Cites: Am J Hum Genet. 2012 Nov 2;91(5):809-2223103233
Cites: J Med Genet. 1993 Oct;30(10):857-658230163
Cites: Nature. 2007 Oct 18;449(7164):851-6117943122
Cites: Genome Res. 2009 Jan;19(1):136-4219029539
Cites: Genome Res. 2009 Feb;19(2):318-2618971310
Cites: Heredity (Edinb). 2013 May;110(5):409-1923423148
Cites: Bioinformatics. 2010 Jun 15;26(12):1569-7120421198
Cites: Lancet Neurol. 2010 Oct;9(10):978-8520801718
Cites: Nat Rev Genet. 2009 Mar;10(3):195-20519204717
Cites: Annu Rev Genomics Hum Genet. 2001;2:103-2811701645
Cites: PLoS Genet. 2013 Jun;9(6):e100352123754952
Cites: Genetics. 2013 Jun;194(2):459-7123535385
Cites: PLoS Biol. 2013;11(5):e100155523667324
PubMed ID
26299365 View in PubMed
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[A computing laboratory-clinical system in the screening of malignant tumors: study of the state of the antioxidant system and level of cellular proliferation markers among the population from the Chernobyl AES accident area]

https://arctichealth.org/en/permalink/ahliterature24950
Source
Vestn Akad Med Nauk SSSR. 1991;(8):36-40
Publication Type
Article
Date
1991
Author
N A Grigorovich
Source
Vestn Akad Med Nauk SSSR. 1991;(8):36-40
Date
1991
Language
Russian
Publication Type
Article
Keywords
Accidents
Antioxidants
Biological Markers
English Abstract
Humans
Middle Aged
Neoplasms, Radiation-Induced - diagnosis - prevention & control
Nuclear Reactors
Radiation Dosage
Risk factors
Software
Time Factors
Ukraine
Abstract
The author bases and describes the computing laboratory and clinical system for screening groups at a higher risk for malignant neoplasms whose incidence is likely to increase due to irradiation. Two years after the disaster the detected group at a higher risk was 2-2.4 times larger than the control group among persons who received the total irradiation dose 5 rem and over as well as among persons who are to be removed from the area polluted with radionuclides whatever the dose. As the time elapsed since the disaster increases, the number of subjects with a higher level of biomarkers also grows. It is advisable that this system be introduced in all fields of the practical health care in the polluted and control areas to carry out goal-oriented treatment and diagnostic measures in the selected population groups.
PubMed ID
1950158 View in PubMed
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The acute abdomen in emergency with Hypercard.

https://arctichealth.org/en/permalink/ahliterature227531
Source
Proc Annu Symp Comput Appl Med Care. 1991;:156-9
Publication Type
Article
Date
1991
Author
A C Harvey
P F Moodie
J E Reda
N J Childs
D. Gray
M. Samimi
D P Thorlakson
Author Affiliation
Department of Medicine, University of Manitoba, Misericordia Hospital, Winnipeg.
Source
Proc Annu Symp Comput Appl Med Care. 1991;:156-9
Date
1991
Language
English
Publication Type
Article
Keywords
Abdomen, Acute - etiology
Bayes Theorem
Consumer Satisfaction
Diagnosis, Computer-Assisted - utilization
Emergency Service, Hospital
Hospitals, Community
Humans
Manitoba
Microcomputers
Software
Abstract
A non-sequential Bayesian program for diagnosing acute abdominal pain was developed using an Amdahl mainframe accessed by a Texas Instrument remote terminal. Transferring the program to a MacIntosh SE/30 using hypercard was attended by increased utilisation from 15 to 44%.
Notes
Cites: Br Med J (Clin Res Ed). 1986 Sep 27;293(6550):800-43094664
Cites: Ann R Coll Surg Engl. 1990 Mar;72(2):140-62185682
Cites: Br J Surg. 1977 Apr;64(4):250-4322788
PubMed ID
1807577 View in PubMed
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[A data bank for the "Disaster Medicine" automated information retrieval system].

https://arctichealth.org/en/permalink/ahliterature222951
Source
Voen Med Zh. 1992 Oct;(10):4-10
Publication Type
Article
Date
Oct-1992
Author
E A Nechaev
V S Krutov
Iu M Zakharov
Source
Voen Med Zh. 1992 Oct;(10):4-10
Date
Oct-1992
Language
Russian
Publication Type
Article
Keywords
Databases, Factual
Disasters
Emergency Medical Services - organization & administration
Humans
Information Systems
Military Medicine
Russia
Software Design
Abstract
The article substantiate the necessity to improve the automatization of the information process in the system of medical support in extreme situations and thus to liquidate the disproportion between the medico-diagnostical and information accumulation storage facilities. These facts clearly define the importance of work which is being carried out by Medical Service towards an elaboration of the "Disaster Medicine" automated information retrieval system (AIRS). The data obtained as a result of AIRS processing could be directly used for reference or prediction purposes.
PubMed ID
1481404 View in PubMed
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570 records – page 1 of 57.