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2-h postchallenge plasma glucose predicts cardiovascular events in patients with myocardial infarction without known diabetes mellitus.

https://arctichealth.org/en/permalink/ahliterature121853
Source
Cardiovasc Diabetol. 2012;11:93
Publication Type
Article
Date
2012
Author
Loghman Henareh
Stefan Agewall
Author Affiliation
Department of Cardiology Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden. loghman.henareh@karolinska.se
Source
Cardiovasc Diabetol. 2012;11:93
Date
2012
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Angina, Unstable - blood - epidemiology - mortality
Biological Markers - blood
Blood Glucose - metabolism
Chi-Square Distribution
Female
Glucose Tolerance Test
Humans
Incidence
Male
Middle Aged
Multivariate Analysis
Myocardial Infarction - blood - epidemiology - mortality
Predictive value of tests
Prognosis
Proportional Hazards Models
Prospective Studies
Recurrence
Risk assessment
Risk factors
Smoking - adverse effects - epidemiology
Stroke - blood - epidemiology - mortality
Sweden - epidemiology
Time Factors
Abstract
The incidence of cardiovascular events remains high in patients with myocardial infarction (MI) despite advances in current therapies. New and better methods for identifying patients at high risk of recurrent cardiovascular (CV) events are needed. This study aimed to analyze the predictive value of an oral glucose tolerance test (OGTT) in patients with acute myocardial infarction without known diabetes mellitus (DM).
The prospective cohort study consisted of 123 men and women aged between 31-80 years who had suffered a previous MI 3-12 months before the examinations. The exclusion criteria were known diabetes mellitus. Patients were followed up over 6.03???1.36 years for CV death, recurrent MI, stroke and unstable angina pectoris. A standard OGTT was performed at baseline.
2-h plasma glucose (HR, 1.27, 95% CI, 1.00 to 1.62; P?
Notes
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PubMed ID
22873202 View in PubMed
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A 2-year self-help smoking cessation manual intervention among middle-aged Finnish men: an application of the transtheoretical model.

https://arctichealth.org/en/permalink/ahliterature217852
Source
Prev Med. 1994 Jul;23(4):507-14
Publication Type
Article
Date
Jul-1994
Author
U E Pallonen
L. Leskinen
J O Prochaska
C J Willey
R. Kääriäinen
J T Salonen
Author Affiliation
Cancer Prevention Research Center, University of Rhode Island, Kingston 02881.
Source
Prev Med. 1994 Jul;23(4):507-14
Date
Jul-1994
Language
English
Publication Type
Article
Keywords
Adult
Analysis of Variance
Chi-Square Distribution
Confounding Factors (Epidemiology)
Finland
Humans
Longitudinal Studies
Male
Manuals as Topic
Middle Aged
Risk factors
Self Care
Smoking Cessation
Abstract
A 2-year self-help manual smoking cessation intervention was conducted among a panel of middle-aged Finnish men (n = 265) who were recruited proactively in a longitudinal cardiovascular risk factor surveillance study.
Intervention utilized the stages of change concept of the transtheoretical model. The stages were assessed in the treatment condition at baseline of the cessation study and after that by mail every sixth month. Assessments were followed by an immediate mailing of a stage-based self-help manual matching the stage of change at that time. A usual care group was assessed annually but received no treatment.
A significant time x intervention effect (P
PubMed ID
7971879 View in PubMed
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A 3 year follow-up study of health care students' sense of coherence and related smoking, drinking and physical exercise factors.

https://arctichealth.org/en/permalink/ahliterature186071
Source
Int J Nurs Stud. 2003 May;40(4):383-8
Publication Type
Article
Date
May-2003
Author
Merja Kuuppelomäki
Pekka Utriainen
Author Affiliation
Research and Development Centre for Social Welfare and Health, Seinäjoki Polytechnic, Koskenalantie 16 Seinäjoki Fin-60220, Finland. merja.kuuppelomaki@seamk.fi
Source
Int J Nurs Stud. 2003 May;40(4):383-8
Date
May-2003
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Alcohol Drinking - psychology
Attitude of Health Personnel
Attitude to Health
Educational Status
Exercise - psychology
Female
Finland
Follow-Up Studies
Health Behavior
Health Knowledge, Attitudes, Practice
Humans
Internal-External Control
Male
Pilot Projects
Questionnaires
Self Efficacy
Smoking - psychology
Students, Health Occupations - psychology
Abstract
The purpose of the study was to describe the sense of coherence (SOC) of three groups of Finnish polytechnic students (n=287) at the beginning of their studies and to follow it during a period of 3 year amongst the health care students (n=63) of this group. The associations between SOC and smoking, drinking and physical exercise were also studied. The data were collected with a questionnaire which included Antonovsky's (Adv. Nurs. Sci. 1(1983)37) SOC scale. Data analysis was with SPSS statistical software. The students showed a strong sense of coherence at the beginning of their studies. Physical activity was related to the strength of SOC, but no association was found with smoking and drinking. Health care students showed a stronger SOC at the beginning of their studies than the two other groups. During the follow-up focused on the health care students, SOC weakened in 6%, remained unchanged in 65% and strengthened in 32% of the participants. Smoking, drinking and physical exercise showed no association with these changes. Future research should be focused on identifying factors that are related to SOC during education.
PubMed ID
12667515 View in PubMed
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7-Alkoxyquinoline O-dealkylation by microsomes from human liver and placenta.

https://arctichealth.org/en/permalink/ahliterature64902
Source
Br J Clin Pharmacol. 1992 Nov;34(5):415-20
Publication Type
Article
Date
Nov-1992
Author
J. Hakkola
J. Mäenpää
R T Mayer
S S Park
H V Gelboin
O. Pelkonen
Author Affiliation
Department of Pharmacology and Toxicology, University of Oulu, Finland.
Source
Br J Clin Pharmacol. 1992 Nov;34(5):415-20
Date
Nov-1992
Language
English
Publication Type
Article
Keywords
Animals
Antibodies, Monoclonal - diagnostic use
Benzyl Compounds - metabolism
Cytochrome P-450 Enzyme System - antagonists & inhibitors - metabolism
Dealkylation
Female
Humans
In Vitro
Male
Mice
Mice, Inbred Strains
Microsomes - enzymology - metabolism
Microsomes, Liver - enzymology - metabolism
Placenta - enzymology - metabolism
Pregnancy
Quinolines - metabolism
Rats
Rats, Wistar
Research Support, Non-U.S. Gov't
Smoking - metabolism
Abstract
1. The O-dealkylation of seven 7-alkoxyquinoline derivatives by human hepatic and placental microsomes and the effect of maternal cigarette smoking on placental 7-alkoxyquinoline metabolism was studied. 2. None of several monoclonal antibodies to isoenzymes of cytochrome P450 had a clear effect on metabolism of the compounds by liver microsomes. 3. Maternal cigarette smoking induced the O-dealkylation of all of the 7-alkoxyquinoline derivatives, being greatest for 7-butoxy- and 7-benzyloxyquinoline. 4. Placental 7-alkoxyquinoline metabolism induced by smoking was partially inhibited by the monoclonal antibody 1-7-1 raised against 3-methylcholanthrene-induced rat liver P450. 5. None of the 7-alkoxyquinoline O-dealkylations could be assigned specifically to any known P450 isoenzyme in human liver or placenta.
PubMed ID
1467136 View in PubMed
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[7 years' experience with physical training in infarct]

https://arctichealth.org/en/permalink/ahliterature55950
Source
Lakartidningen. 1979 Dec 12;76(50):4617-21
Publication Type
Article
Date
Dec-12-1979

A 9-year follow-up study of participants and nonparticipants in sigmoidoscopy screening: importance of self-selection.

https://arctichealth.org/en/permalink/ahliterature93168
Source
Cancer Epidemiol Biomarkers Prev. 2008 May;17(5):1163-8
Publication Type
Article
Date
May-2008
Author
Blom Johannes
Yin Li
Lidén Annika
Dolk Anders
Jeppsson Bengt
Påhlman Lars
Holmberg Lars
Nyrén Olof
Author Affiliation
Division of Surgery, Department for Clinical Science, Intervention and Technology, Karolinska Institutet at Karolinska University Hospital, K53, Huddinge, 141 86 Stockholm, Sweden. johannes.blom@ki.se
Source
Cancer Epidemiol Biomarkers Prev. 2008 May;17(5):1163-8
Date
May-2008
Language
English
Publication Type
Article
Keywords
Cause of Death
Colorectal Neoplasms - mortality - prevention & control
Female
Follow-Up Studies
Gastrointestinal Neoplasms - mortality
Health Behavior
Humans
Incidence
Lung Neoplasms - mortality
Male
Mass Screening
Middle Aged
Poisson Distribution
Registries
Sigmoidoscopy - utilization
Smoking - adverse effects
Sweden - epidemiology
Abstract
BACKGROUND: Self-selection may compromise cost-effectiveness of screening programs. We hypothesized that nonparticipants have generally higher morbidity and mortality than participants. METHODS: A Swedish population-based random sample of 1,986 subjects ages 59 to 61 years was invited to sigmoidoscopy screening and followed up for 9 years by means of multiple record linkages to health and population registers. Gender-adjusted cancer incidence rate ratio (IRR) and overall and disease group-specific and mortality rate ratio (MRR) with 95% confidence intervals (95% CI) were estimated for nonparticipants relative to participants. Cancer and mortality rates were also estimated relative to the age-matched, gender-matched, and calendar period-matched Swedish population using standardized incidence ratios and standardized mortality ratios. RESULTS: Thirty-nine percent participated. The incidence of colorectal cancer (IRR, 2.2; 95% CI, 0.8-5.9), other gastrointestinal cancer (IRR, 2.7; 95% CI, 0.6-12.8), lung cancer (IRR, 2.2; 95% CI, 0.8-5.9), and smoking-related cancer overall (IRR, 1.4; 95% CI, 0.7-2.5) tended to be increased among nonparticipants relative to participants. Standardized incidence ratios for most of the studied cancers tended to be >1.0 among nonparticipants and
PubMed ID
18483338 View in PubMed
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A 10 year asthma programme in Finland: major change for the better.

https://arctichealth.org/en/permalink/ahliterature168103
Source
Thorax. 2006 Aug;61(8):663-70
Publication Type
Article
Date
Aug-2006
Author
T. Haahtela
L E Tuomisto
A. Pietinalho
T. Klaukka
M. Erhola
M. Kaila
M M Nieminen
E. Kontula
L A Laitinen
Author Affiliation
Skin and Allergy Hospital, Helsinki University Central Hospital, P O Box 160, FIN-00029 HUS, Finland. tari.haahtela@hus.fi
Source
Thorax. 2006 Aug;61(8):663-70
Date
Aug-2006
Language
English
Publication Type
Article
Keywords
Adult
Anti-Asthmatic Agents - therapeutic use
Asthma - economics - epidemiology - therapy
Child
Communication
Cost of Illness
Disabled Persons
Emergency Treatment - statistics & numerical data
Finland - epidemiology
Health Promotion - economics - organization & administration - trends
Hospitalization - statistics & numerical data
Humans
Incidence
Insurance, Disability - economics
Interprofessional Relations
National Health Programs - economics - trends
Pharmaceutical Services - standards
Primary Health Care
Program Evaluation
Smoking - epidemiology
Abstract
A National Asthma Programme was undertaken in Finland from 1994 to 2004 to improve asthma care and prevent an increase in costs. The main goal was to lessen the burden of asthma to individuals and society.
The action programme focused on implementation of new knowledge, especially for primary care. The main premise underpinning the campaign was that asthma is an inflammatory disease and requires anti-inflammatory treatment from the outset. The key for implementation was an effective network of asthma-responsible professionals and development of a post hoc evaluation strategy. In 1997 Finnish pharmacies were included in the Pharmacy Programme and in 2002 a Childhood Asthma mini-Programme was launched.
The incidence of asthma is still increasing, but the burden of asthma has decreased considerably. The number of hospital days has fallen by 54% from 110 000 in 1993 to 51 000 in 2003, 69% in relation to the number of asthmatics (n = 135 363 and 207 757, respectively), with the trend still downwards. In 1993, 7212 patients of working age (9% of 80 133 asthmatics) received a disability pension from the Social Insurance Institution compared with 1741 in 2003 (1.5% of 116 067 asthmatics). The absolute decrease was 76%, and 83% in relation to the number of asthmatics. The increase in the cost of asthma (compensation for disability, drugs, hospital care, and outpatient doctor visits) ended: in 1993 the costs were 218 million euro which had fallen to 213.5 million euro in 2003. Costs per patient per year have decreased 36% (from 1611 euro to 1031 euro).
It is possible to reduce the morbidity of asthma and its impact on individuals as well as on society. Improvements would have taken place without the programme, but not of this magnitude.
Notes
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PubMed ID
16877690 View in PubMed
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The 10-year COPD Programme in Finland: effects on quality of diagnosis, smoking, prevalence, hospital admissions and mortality.

https://arctichealth.org/en/permalink/ahliterature135938
Source
Prim Care Respir J. 2011 Jun;20(2):178-83
Publication Type
Article
Date
Jun-2011
Author
Vuokko L Kinnula
Tuula Vasankari
Eva Kontula
Anssi Sovijarvi
Olli Saynajakangas
Anne Pietinalho
Author Affiliation
Department of Medicine, Division of Pulmonary Medicine, University of Helsinki, Helsinki, Finland. vuokko.kinnula@helsinki.fi
Source
Prim Care Respir J. 2011 Jun;20(2):178-83
Date
Jun-2011
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Diagnostic Techniques, Respiratory System - standards
Female
Finland - epidemiology
Hospitalization - trends
Humans
Male
Middle Aged
Prevalence
Program Evaluation - methods
Pulmonary Disease, Chronic Obstructive - diagnosis - epidemiology - therapy
Quality Assurance, Health Care
Retrospective Studies
Smoking - adverse effects - epidemiology
Smoking Cessation - statistics & numerical data
Survival Rate - trends
Young Adult
Abstract
The Finnish National Programme for Chronic Bronchitis and Chronic Obstructive Pulmonary Disease (COPD) 1998-2007 was set up to reduce the prevalence of COPD, improve COPD diagnosis and care, reduce the number of moderate to severe cases of the disease, and reduce hospitalisations and treatment costs due to COPD. Over 900 events for 25,000 participating healthcare workers were arranged. The major strengths of this programme included multidisciplinary strategies and web-based guidelines in nearly all primary health care centres around the country.
Data from national registries, epidemiological studies and questionnaires were used to measure whether the goals had been reached.
The prevalence of COPD remained unchanged. Smoking decreased in males from 30% to 26% (p
Notes
Comment In: Prim Care Respir J. 2011 Jun;20(2):109-1021603847
PubMed ID
21431275 View in PubMed
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A 10-year prospective study of tobacco smoking and periodontal health.

https://arctichealth.org/en/permalink/ahliterature67464
Source
J Periodontol. 2000 Aug;71(8):1338-47
Publication Type
Article
Date
Aug-2000
Author
J. Bergström
S. Eliasson
J. Dock
Author Affiliation
Department of Periodontology, Karolinska Institutet, Stockholm, Sweden.
Source
J Periodontol. 2000 Aug;71(8):1338-47
Date
Aug-2000
Language
English
Publication Type
Article
Keywords
Adult
Age Factors
Aged
Alveolar Bone Loss - epidemiology
Analysis of Variance
Cohort Studies
Comparative Study
Dental Plaque Index
Female
Follow-Up Studies
Gingival Hemorrhage - epidemiology
Humans
Linear Models
Longitudinal Studies
Male
Middle Aged
Music
Observer Variation
Oral Hygiene
Periodontal Diseases - epidemiology
Periodontal Pocket - epidemiology
Population Surveillance
Prospective Studies
Regression Analysis
Smoking - epidemiology
Smoking Cessation - statistics & numerical data
Sweden - epidemiology
Abstract
BACKGROUND: To date only a few studies have evaluated the long-term influence of smoking and smoking cessation on periodontal health. The present study, therefore, was undertaken with the aim to prospectively investigate the influence of smoking exposure over time on the periodontal health condition in a targeted population before and after a follow-up interval of 10 years. METHODS: The primary study base consisted of a population of occupational musicians that was investigated the first time in 1982 and scheduled for reinvestigation in 1992 and 2002. The 1992 investigation included 101 individuals from the baseline study constituting a prospective cohort including 16 smokers, who had continued to smoke throughout the entire length of the 10-year period; 28 former smokers who had ceased smoking an average of approximately 9 years before the commencement of the baseline study; 40 non-smokers, who denied ever having smoked tobacco; and 17 individuals whose smoking pattern changed or for whom incomplete data were available. The clinical and radiographic variables used for the assessment of the periodontal health condition of the individual were frequency of periodontally diseased sites (probing depth > or =4 mm), gingival bleeding (%), and periodontal bone height (%). The oral hygiene standard was evaluated by means of a standard plaque index. RESULTS: The changes over the 10 years with respect to frequency of diseased sites indicated an increased frequency in continuous smokers versus decreased frequencies in former smokers and non-smokers. Controlling for age and frequency of diseased sites at baseline, the 10-year change was significantly associated with smoking (P
PubMed ID
10972650 View in PubMed
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8975 records – page 1 of 898.