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ABH secretion polymorphism in Icelanders, Aland Islanders, Finns, Finnish Lapps, Komi and Greenland Eskimos: a review and new data.

https://arctichealth.org/en/permalink/ahliterature237022
Source
Ann Hum Biol. 1986 May-Jun;13(3):273-85
Publication Type
Article
Author
A W Eriksson
K. Partanen
R R Frants
J C Pronk
P J Kostense
Source
Ann Hum Biol. 1986 May-Jun;13(3):273-85
Language
English
Publication Type
Article
Keywords
ABO Blood-Group System - genetics
Adult
Aged
Alleles
Asian Continental Ancestry Group
European Continental Ancestry Group
Finland
Greenland
Humans
Iceland
Inuits
Male
Polymorphism, Genetic
Saliva - immunology
Sweden - ethnology
Abstract
The secretion of the ABH antigens in saliva was tested in indigenous individuals of several populations: Icelanders in Reykjavik and Husavik (northeastern Iceland), Aland Islanders, Finno-Ugrians (Finns, Finnish Lapps, Komi) and Eskimos (Augpilagtok, northwestern Greenland). The frequencies of ABH non-secretors among the Icelanders (28-36%) were among the highest ever noted in Europeans. Among Alanders and Swedes on the Finnish mainland the frequency (around 20%) was comparable to Swedish values but considerably higher than among Finns (13-14%). The values among northeastern Finns and Komi (about 9%) were intermediate between values among Lapps (below 5%) and Scandinavians (15-26%), excluding Icelanders (28-41%). The average frequency of non-secretors among Lapps in Finland (2.2 +/- 0.5%) was the lowest observed among white populations. Like many other arctic populations of the Mongolian race, the Greenland Eskimos had a very low frequency of non-secretors. It is probable that the non-secretor allele ABH*se was absent from the ancient Lapps and Greenland Eskimos but introduced by invading populations. It is concluded that the ABH*se allele frequencies vary much more among northern European populations than hitherto appreciated. Recent studies indicate that the non-secretor status of the ABH blood group substances in mucous body fluids is associated with pathological conditions of the mucous membranes of the embryologically related digestive and respiratory systems, particularly with duodenal ulcer and gastric (pre)malignancies but probably also with pulmonary dysfunction. In view of these disadvantages of the ABH non-secretor status the high frequency of ABH*se in Icelanders is a paradoxical phenomenon. The frequency of ABH non-secretors among the founders (Vikings) of Iceland may have been considerably higher than among the present populations in northwestern Europe. The increase in northwestern direction of the ABH*se allele frequencies supports this hypothesis; the dilution effect has not been as strong in Iceland as on the European continent.
PubMed ID
3752918 View in PubMed
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[A Legionella circulation study in the central Volga Valley area].

https://arctichealth.org/en/permalink/ahliterature220029
Source
Zh Mikrobiol Epidemiol Immunobiol. 1993 Nov-Dec;(6):52-3
Publication Type
Article

Allergic diseases and asthma in relation to serum immunoglobulins and salivary immunoglobulin A in pre-school children: a follow-up community-based study.

https://arctichealth.org/en/permalink/ahliterature15099
Source
Clin Exp Allergy. 2005 Jan;35(1):64-9
Publication Type
Article
Date
Jan-2005
Author
B R Lúethvíksson
G J Arason
O. Thorarensen
B. Ardal
H. Valdimarsson
Author Affiliation
Department of Immunology, Institute of Laboratory Medicine, Landspítali University Hospital, Reykjavík, Iceland. bjornlud@landspitali.is
Source
Clin Exp Allergy. 2005 Jan;35(1):64-9
Date
Jan-2005
Language
English
Publication Type
Article
Keywords
Asthma - immunology
Child, Preschool
Comparative Study
Dermatitis, Atopic - immunology
Follow-Up Studies
Humans
Hypersensitivity - blood
Immunoglobulin A - analysis - blood
Immunoglobulin E - blood
Immunoglobulin G - blood
Infant, Newborn
Rhinitis, Allergic, Seasonal - immunology
Saliva - immunology
Skin Tests
Statistics, nonparametric
Time Factors
Abstract
BACKGROUND: We have previously reported an association between low IgA and allergic manifestations in early childhood (0-2 years) and have now followed our cohort for an additional 2 years. OBJECTIVE: To evaluate in a longitudinal community-based cohort study the association between maturation of Ig production and allergic manifestations in the first 4 years of life. METHODS: A cohort of 161 randomly selected children was followed from birth to the age of 42-48 months and evaluated at 18-23 months (EV1; n = 179) and again at the age of 42-48 months (EV2; n = 161). Diagnoses were made with the help of a clinical questionnaire, physical examination and skin prick tests (SPTs) to 10 common allergens. Serum immunoglobulins were measured at EV1 and EV2, and salivary IgA (sal-IgA) at EV2. RESULTS: Serum IgA, IgE, IgG1, IgG2 and IgG4 increased from 2 to 4 years of age (P
PubMed ID
15649268 View in PubMed
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Antibodies to indigenous and laboratory strains of Streptococcus mutans in saliva from children with dental caries and from caries-free children.

https://arctichealth.org/en/permalink/ahliterature234798
Source
Pediatr Dent. 1987 Sep;9(3):216-20
Publication Type
Article
Date
Sep-1987

Avidity and titers of the antibody response to two inactivated poliovirus vaccines with different antigen content.

https://arctichealth.org/en/permalink/ahliterature36236
Source
Acta Paediatr. 1993 Jun-Jul;82(6-7):552-6
Publication Type
Article
Author
L. Mellander
M. Böttiger
L A Hanson
J. Taranger
B. Carlsson
Author Affiliation
Department of Paediatrics, Västra Frölunda Hospital, University of Göteborg, Sweden.
Source
Acta Paediatr. 1993 Jun-Jul;82(6-7):552-6
Language
English
Publication Type
Article
Keywords
Antibodies, Viral - analysis - biosynthesis
Antibody Affinity
Antigens, Viral
Comparative Study
Enzyme-Linked Immunosorbent Assay
Humans
Immunization Schedule
Infant
Netherlands
Poliovirus Vaccine, Inactivated - administration & dosage - immunology
Polioviruses - immunology
Research Support, Non-U.S. Gov't
Saliva - immunology
Sweden
Abstract
The inactivated poliovirus vaccine is heat stabile, gives high serum IgG concentrations but less pronounced mucosal immunity and must be given as repeated injections. A new enhanced-potency Dutch inactivated vaccine could circumvent these difficulties. We compared antibody concentrations measured as neutralization or ELISA titers, and avidity of serum and salivary antibodies in children vaccinated with three doses of the earlier Swedish vaccine given over nine months or the new antigen-rich vaccine. After three doses, but not after two, serum neutralization titers for type 1 and type 3 poliovirus were higher using the new vaccine but secretory IgA levels in saliva were similar. The avidity of the serum IgG antibodies was significantly higher after two doses of the new vaccine than after three doses of the old. Thus the new vaccine gives excellent antibody responses of high titers and avidities, but should preferably be given in three doses.
PubMed ID
8393360 View in PubMed
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Continuing HIV transmission among injection drug users in Eastern Central Canada: the SurvUDI Study, 1995 to 2000.

https://arctichealth.org/en/permalink/ahliterature189156
Source
J Acquir Immune Defic Syndr. 2002 Aug 15;30(5):514-21
Publication Type
Article
Date
Aug-15-2002
Author
Catherine Hankins
Michel Alary
Raymond Parent
Caty Blanchette
Christiane Claessens
Author Affiliation
Direction de la santé publique de Montréal-centre, Montréal, Canada. catherine.hankins@mcgill.ca
Source
J Acquir Immune Defic Syndr. 2002 Aug 15;30(5):514-21
Date
Aug-15-2002
Language
English
Publication Type
Article
Keywords
AIDS Serodiagnosis
Adolescent
Adult
Aged
Canada - epidemiology
Female
HIV Infections - diagnosis - transmission
Health Surveys
Humans
Immunoenzyme Techniques
Incidence
Male
Middle Aged
Mouth - immunology
Needle-Exchange Programs
Population Surveillance
Prevalence
Risk factors
Saliva - immunology
Substance Abuse, Intravenous - complications
Abstract
To document HIV prevalence/incidence trends from 1995-2000 and associated risk factors among injection drug users (IDUs) in Eastern Central Canada as an indication of harm reduction strategy effectiveness.
Nonnominal cross-sectional data (one-time participants) and longitudinal data (repeat participants) were collected using convenience sampling. Participants provided informed consent for face-to-face interviews focused on injection drug use and sexual practices during the previous 6 months; oral fluid samples were taken for HIV testing by enzyme immunoassay. Unique encrypted codes for initially HIV-negative repeat participants permitted incidence rate calculations.
In all, 6387 IDUs (median age, 31 years; range, 13-67; males, 73.5%) participated on 9724 occasions. HIV prevalence ranged from 4.7% (95% confidence interval [CI], 2.9-6.5) in semiurban areas to 20.1% (95% CI, 17.6-22.7) in Ottawa, Ontario. HIV incidence was 6.0 (95%CI, 4.5-7.6) per 100 person-years (py) in Montréal, Québec, 3.2 (95% CI, 2.2-4.2) per 100 py in Québec City and 7.0 (95% CI, 4.1-9.8) per 100 py in Ottawa/Hull. Reusing other IDUs' needles was reported by 38.4%. In multivariate logistic regression, IDUs injecting for 6 or more years were more likely to be HIV positive, particularly if cocaine was the predominant drug injected. Multivariate Cox regression revealed higher HIV incidence among those who predominantly injected cocaine, reused others' needles, had injected 6 years or more, injected with strangers, or were men reporting commercial sex work.
These results reveal a volatile situation of continuing HIV transmission among IDUs in Eastern Central Canada.
PubMed ID
12154342 View in PubMed
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Correlates of mucosal immunity and upper respiratory tract infections in girls.

https://arctichealth.org/en/permalink/ahliterature141902
Source
J Pediatr Endocrinol Metab. 2010 Jun;23(6):579-87
Publication Type
Article
Date
Jun-2010
Author
Lauren Corbett
Cameron Muir
Izabella A Ludwa
Matthew Yao
Brian W Timmons
Bareket Falk
Panagiota Klentrou
Author Affiliation
Faculty of Applied Health Sciences, Department of Psychology, Brock University, Ontario, Canada.
Source
J Pediatr Endocrinol Metab. 2010 Jun;23(6):579-87
Date
Jun-2010
Language
English
Publication Type
Article
Keywords
Adiposity - immunology
Adolescent
Canada - epidemiology
Child
Female
Humans
Hydrocortisone - metabolism
Immunity, Mucosal - physiology
Immunoglobulin A, Secretory - analysis
Motor Activity - immunology
Puberty, Precocious - immunology
Respiratory Tract Infections - epidemiology - immunology
Risk factors
Saliva - immunology
Testosterone - metabolism
Abstract
In this study we examined whether salivary hormones, physical activity and adiposity were correlated with secretory immunoglobulin A (sIgA) and frequency of upper respiratory tract infections (URTI) in 43 early-pubertal and 59 late-pubertal girls. Physical activity was measured using accelerometers and relative body fat was assessed using bioelectrical impendence. Resting saliva samples were obtained between 1500 and 1800 hr and assayed for sIgA, cortisol and testosterone. Participants completed a one-month health log to record URTI frequency. Early-pubertal girls were more physically active, had less adiposity, but lower concentrations of sIgA than late-pubertal adolescents (122.7 +/- 91.6 vs 201.9 +/- 102.9 pg/ml, respectively). The frequency of URTI was similar in the two groups. Neither sIgA nor URTI were correlated with salivary hormones, physical activity or adiposity within the early-pubertal girls. In the late-pubertal group, sIgA was negatively associated (r = -0.44; p
PubMed ID
20662331 View in PubMed
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[Detection of herpesvirus markers in patients with precancerous lesions of the lungs and stomach]

https://arctichealth.org/en/permalink/ahliterature18396
Source
Vopr Onkol. 2003;49(2):156-9
Publication Type
Article
Date
2003
Author
E N Kologrivova
A A Shishkov
O V Cheremisina
A B Karnov
M P Lebedev
Author Affiliation
Research Institute of Oncology, Siberian Branch of Russian Academy of Medical Sciences, Tomsk.
Source
Vopr Onkol. 2003;49(2):156-9
Date
2003
Language
Russian
Publication Type
Article
Keywords
Antibodies, Viral - blood
Bronchitis - immunology - virology
Chronic Disease
Cytomegalovirus - genetics - immunology - isolation & purification
DNA, Viral - blood
English Abstract
Gastritis, Atrophic - immunology - virology
Herpesvirus 4, Human - genetics - immunology - isolation & purification
Humans
Lymphocytes - immunology - virology
Mouth Mucosa - immunology - virology
Precancerous Conditions - immunology - virology
Saliva - immunology - virology
Simplexvirus - genetics - immunology - isolation & purification
Abstract
Blood-serum concentrations of antibodies to such viruses as herpes simplex virus, cytomegalovirus and Epstein--Barr virus have been assayed versus frequency of viral DNA detection in blood and saliva suspensions from patients with lung and stomach pre-cancers. Condition of local immunity of oral mucosa was assessed on the basis of saliva levels of secretory IgA and lysozyme. It was found that as local immunity of oral mucosa deteriorated, irrespective of pre-cancer localization, high titers of antiviral antibodies (class G) were established. The frequency of herpes DNA was much higher in lymphocytes and cellular sediment from saliva of patients with gastric pre-cancers. The role of herpes viruses in the pathogenesis of precancerous diseases and malignances is discussed.
PubMed ID
12785195 View in PubMed
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Determinants of HIV-related high risk behaviours among young offenders: a window of opportunity.

https://arctichealth.org/en/permalink/ahliterature210218
Source
Can J Public Health. 1997 Jan-Feb;88(1):14-7
Publication Type
Article
Author
D A Rothon
S A Strathdee
D. Cook
P G Cornelisse
Author Affiliation
Health Services, Ministry of the Attorney General of British Columbia, Victoria.
Source
Can J Public Health. 1997 Jan-Feb;88(1):14-7
Language
English
Publication Type
Article
Keywords
AIDS Serodiagnosis
Adolescent
Adult
British Columbia - epidemiology
Chi-Square Distribution
Child
Female
HIV Infections - epidemiology
Humans
Logistic Models
Male
Prisons - statistics & numerical data
Risk factors
Saliva - immunology
Sexual Behavior - statistics & numerical data
Substance Abuse, Intravenous - complications - epidemiology
Abstract
To study HIV-associated risk behaviours among young offenders.
Juveniles aged 12 to 19 years entering correctional facilities in British Columbia volunteered in an unlinked anonymous study. Logistic regression was used to identify factors associated with high-risk sexual behaviours and injection drug use (IDU).
Despite low HIV prevalence (0.25%), patterns of risk behaviour were evident. IDU and homosexual/bisexual activity were equally prevalent among youth aged 12 to 15 and 16 to 19 years. For both age groups, IDU and female gender were significant predictors of sex for trade and sex with another drug user. Natives aged 12 to 15 years were five times more likely to inject drugs than non-Natives. However, predictors of IDU differed for older vs. younger youth.
Patterns of high-risk activity begin early and selective pressures may differ for younger vs. older young offenders. Youth in detention provide a window of opportunity for enhanced HIV/AIDS education.
PubMed ID
9094798 View in PubMed
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55 records – page 1 of 6.