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2-year clinical performance of a fluoride-containing fissure sealant in young schoolchildren at caries risk.

https://arctichealth.org/en/permalink/ahliterature34233
Source
Am J Dent. 1997 Jun;10(3):115-9
Publication Type
Article
Date
Jun-1997
Author
A. Carlsson
M. Petersson
S. Twetman
Author Affiliation
Public Dental Clinic, Vallås, Sweden.
Source
Am J Dent. 1997 Jun;10(3):115-9
Date
Jun-1997
Language
English
Publication Type
Article
Keywords
Analysis of Variance
Cariostatic Agents - analysis - therapeutic use
Chi-Square Distribution
Child
Colony Count, Microbial
Composite Resins - chemistry - therapeutic use
Dental Caries - epidemiology - prevention & control
Dental Plaque - microbiology
Fluorides - analysis - pharmacology - therapeutic use
Humans
Lactobacillus - drug effects - isolation & purification
Pit and Fissure Sealants - therapeutic use
Prevalence
Risk assessment
Saliva - chemistry - microbiology
Statistics, nonparametric
Streptococcus mutans - drug effects - isolation & purification
Sweden - epidemiology
Abstract
PURPOSE: To evaluate the clinical performance of Helioseal-F, a fluoride-containing fissure sealant, in school children at caries risk. MATERIALS AND METHODS: A caries risk assessment based on past caries experience, saliva microbial tests, buffer capacity and frequency of sugar intake was carried out in 204 healthy children, 6-7 years of age. Children exhibiting one or more risk factors were considered at caries risk (n = 121) and their permanent molars were sealed with a fluoride-containing fissure sealant, thus forming a fissure sealant group (FSG). The remaining 83 children with low caries risk received no fissure sealants and constituted a reference group (RG). Both groups were followed for 2 years. From 15 children of both groups, unstimulated whole saliva was collected 1 month after sealant placement in order to determine fluoride levels. In another 20 children, a split-mouth study design was utilized to compare the colonization of mutans streptococci adjacent to and on F-containing sealants and conventional controls. The sealants were placed by dental hygienists according to the manufacturers' instructions. RESULTS: A total of 431 fissure sealants were placed at baseline. Complete retention was found in 76.6% during the study period while 22.0% were partially lost. Six sealants (1.4%) were completely lost. The enamel caries incidence was 45% lower (P
PubMed ID
9545884 View in PubMed
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Associations between salivary calcium and oral health.

https://arctichealth.org/en/permalink/ahliterature203696
Source
J Clin Periodontol. 1998 Nov;25(11 Pt 1):915-9
Publication Type
Article
Date
Nov-1998
Author
L A Sewón
S M Karjalainen
E. Söderling
H. Lapinleimu
O. Simell
Author Affiliation
Department of Periodontology, Institute of Dentistry, University of Turku, Finland.
Source
J Clin Periodontol. 1998 Nov;25(11 Pt 1):915-9
Date
Nov-1998
Language
English
Publication Type
Article
Keywords
Adult
Analysis of Variance
Calcium - analysis
Chi-Square Distribution
Female
Finland
Food Habits
Humans
Male
Oral Health
Random Allocation
Saliva - chemistry - microbiology
Abstract
Recently, we have shown positive correlations between high salivary calcium content and periodontitis, and between high salivary calcium level and the number of intact teeth in selected groups of subjects. The aim of our present study was to determine whether these correlations could be seen in a randomized group of healthy adults. A thorough oral examination including orthopantomograms was carried out for a total of 137 healthy subjects, 63 men (35.4+/-5.6 years) and 74 women (33.2+/-4.7 years). Paraffin-stimulated saliva was collected from the subjects and salivary flow (ml/min), buffering capacity, calcium (mMol/l) and microbial variables including lactobacilli, yeasts, mutans streptococci, total streptococci, total number of aerobes, and anaerobes were determined. The calcium level of whole saliva had a median of 1.23 mMol/l. Subjects with calcium level below the median were categorized as 'low', while those with higher values formed the 'high' salivary calcium group. There were more men than women in the 'High' salivary calcium group (p=0.025). Subjects in the 'high' calcium group showed more bleeding on probing (p=0.026), had more intact teeth (p=0.045), and lower DMF-scores (p=0.025) than their counterparts. No other differences were found between the two groups. We found clear associations between the level of salivary calcium and factors reflecting gingival health on one hand, and dental health on the other in a randomly selected group of healthy subjects, and conclude that salivary calcium may be important with regard to both dental and gingival health.
PubMed ID
9846801 View in PubMed
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Controlled study of the association of smoking with lactobacilli, mutans streptococci and yeasts in saliva.

https://arctichealth.org/en/permalink/ahliterature52728
Source
Eur J Oral Sci. 1996 Oct-Dec;104(5-6):619-22
Publication Type
Article
Author
T. Sakki
M. Knuuttila
Author Affiliation
Department of Periodontology and Geriatric Dentistry, University of Oulu, Finland.
Source
Eur J Oral Sci. 1996 Oct-Dec;104(5-6):619-22
Language
English
Publication Type
Article
Keywords
Colony Count, Microbial
DMF Index
Dentures
Diet, Cariogenic
Dietary Sucrose
Female
Humans
Hydrogen-Ion Concentration
Lactobacillus - isolation & purification
Logistic Models
Male
Middle Aged
Multivariate Analysis
Oral Hygiene
Saliva - chemistry - microbiology - secretion
Secretory Rate
Smoking
Streptococcus mutans - isolation & purification
Yeasts - isolation & purification
Abstract
The effect of smoking on salivary microbe levels was studied in 780 subjects by multivariate analysis, taking into account some confounding factors. Lactobacilli, mutans streptococci and yeasts were detected with Dentocult-LB, Dentocult-SM and Oricult-N tests. The explanatory variables considered were gender, presence of natural teeth, presence of removable denture, presence of decayed teeth, toothbrushing frequency, use of sugar in coffee or tea, consumption frequency of sugary products, secretion rate of stimulated and unstimulated saliva, buffering capacity of saliva, pH of saliva, oral hygiene and tobacco smoking habits. Smoking was strongly associated with higher lactobacilli counts and presence of yeasts, independently of oral status, hygiene or salivary factors. The relation between smoking and mutans streptococci was weaker. The overall associations of lactobacilli and yeasts with the study variables followed a very similar pattern.
PubMed ID
9021335 View in PubMed
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Dental plaque formation and salivary mutans streptococci in schoolchildren after use of xylitol-containing chewing gum.

https://arctichealth.org/en/permalink/ahliterature78966
Source
Int J Paediatr Dent. 2007 Mar;17(2):79-85
Publication Type
Article
Date
Mar-2007
Author
Holgerson Pernilla Lif
Sjöström Inger
Stecksén-Blicks Christina
Twetman Svante
Author Affiliation
Department of Odontology, Paediatric Dentistry, Faculty of Medicine, Umeå University, Umeå, Sweden. pernilla.lif@odont.umu.se
Source
Int J Paediatr Dent. 2007 Mar;17(2):79-85
Date
Mar-2007
Language
English
Publication Type
Article
Keywords
Analysis of Variance
Chewing Gum
Child
Colony Count, Microbial
DMF Index
Dental Plaque - prevention & control
Dose-Response Relationship, Drug
Double-Blind Method
Humans
Lactic Acid - analysis
Maltose - administration & dosage - analogs & derivatives
Saliva - chemistry - microbiology
Sorbitol - administration & dosage
Streptococcus mutans - drug effects
Sugar Alcohols - administration & dosage
Sweetening Agents - administration & dosage
Xylitol - administration & dosage
Abstract
OBJECTIVE: The aim of this study was to investigate the effect of a fixed daily dose of xylitol on mutans streptococci in saliva and the amount of visible dental plaque. A second aim was to explore if the possible effects differed between children with and without caries experience. METHODS: The study was designed as a double-blind randomized controlled trial with two parallel arms. All pupils (n=149) in grades 1-6 in a comprehensive school in northern Sweden were invited, and 128 children (mean age=12.7 years) consented to participate. The children were stratified as having caries experience (DMFS/dmfs>or=1) or not before the random allocation to a test or control group. The control group (A) was given two pellets containing sorbitol and maltitol three times daily for 4 weeks, and the test group (B) received corresponding pellets with xylitol as single sweetener (total dose=6.18 g day). Clinical scoring and saliva samples were collected at baseline and immediately after the test period. The outcome measures were visible plaque index, salivary mutans streptococci counts and salivary lactic acid production. RESULTS: The amount of visible plaque was significantly reduced in both groups after 4 weeks (P
PubMed ID
17263856 View in PubMed
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Pre- and post-treatment levels of salivary mutans streptococci and lactobacilli in pre-school children.

https://arctichealth.org/en/permalink/ahliterature33104
Source
Int J Paediatr Dent. 1999 Jun;9(2):93-8
Publication Type
Article
Date
Jun-1999
Author
S. Twetman
B. Fritzon
B. Jensen
U. Hallberg
B. Ståhl
Author Affiliation
Department of Paediatric Dentistry, Medical and Dental Center, Halmstad, Sweden.
Source
Int J Paediatr Dent. 1999 Jun;9(2):93-8
Date
Jun-1999
Language
English
Publication Type
Article
Keywords
Anesthesia, Dental
Anesthesia, General
Child
Child, Preschool
Colony Count, Microbial
DMF Index
Dental Caries - epidemiology - therapy
Dental Restoration, Permanent - statistics & numerical data
Humans
Hydrogen-Ion Concentration
Lactobacillus - isolation & purification
Outcome Assessment (Health Care)
Prevalence
Saliva - chemistry - microbiology
Streptococcus mutans - isolation & purification
Sweden - epidemiology
Tooth Extraction - statistics & numerical data
Abstract
OBJECTIVES: To examine the effect of operative and restorative treatment of dental caries on the levels of caries associated microorganisms in saliva and to relate alterations to the type and extent of treatment. DESIGN: Longitudinal. SETTING: Paediatric Dentistry Department at a central hospital in Sweden. SUBJECTS AND METHODS: One hundred and eight pre-school children with severe dental caries scheduled for treatment under general anaesthesia. Chair-side tests were used to estimate the levels of salivary mutans streptococci, lactobacilli and buffer capacity before the surgery and at recall appointments 1 and 6 months after treatment. Caries were assessed according to WHO guidelines and the number of extracted teeth and filled surfaces during surgery were recorded. RESULTS: The results demonstrate that the post-treatment levels of mutans streptococci and lactobacilli were significantly reduced (P
PubMed ID
10530217 View in PubMed
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Salivary factors in children and adolescents with insulin-dependent diabetes mellitus.

https://arctichealth.org/en/permalink/ahliterature34730
Source
Pediatr Dent. 1996 Jul-Aug;18(4):306-11
Publication Type
Article
Author
K M Karjalainen
M L Knuuttila
M L Käär
Author Affiliation
Department of Periodontology and Geriatric Dentistry, University of Oulu, Finland.
Source
Pediatr Dent. 1996 Jul-Aug;18(4):306-11
Language
English
Publication Type
Article
Keywords
Adolescent
Analysis of Variance
Blood Glucose - analysis
Candida - isolation & purification
Child
Colony Count, Microbial
Comparative Study
Diabetes Mellitus, Type 1 - physiopathology
Female
Glucose - analysis
Hemoglobin A, Glycosylated - analysis
Humans
Hyperglycemia - physiopathology
Lactobacillus - isolation & purification
Male
Research Support, Non-U.S. Gov't
Saliva - chemistry - microbiology - secretion
Secretory Rate
Statistics, nonparametric
Abstract
To determine whether hyperglycemia in IDDM (insulin-dependent diabetes mellitus) could interfere with salivary secretion rates, salivary glucose levels, and salivary microbial counts, we studied salivary factors in two groups of children and adolescents with IDDM. One study group included 14 children with newly diagnosed IDDM )mean age 11 years, SD +/- 2.4 years). Samples of saliva were collected on admission to hospital and after 2 weeks on insulin treatment. The other study group were 50 IDDM children (mean age 14.4 years, SD +/- 1.7 years, mean duration of diabetes 6.2 years, SD +/- 1.4 years) visiting the outpatient diabetic clinic. Samples of saliva were collected during two visits, approximately 3 months apart. In the newly diagnosed IDDM cases, mean salivary glucose level decreased from 54.1 +/- 31.7 mg/l to 35.2 +/- 29.5 mg/l (P = 0.096) after beginning insulin treatment. During hyperglycemia, salivary glucose levels correlated with mean blood glucose levels for the day concerned (r = 0.65, P
PubMed ID
8857659 View in PubMed
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Salivary levels of lactobacilli, buffer capacity and salivary flow rate related to caries activity among adults in communities with optimal and low water fluoride concentrations.

https://arctichealth.org/en/permalink/ahliterature224843
Source
Swed Dent J. 1992;16(6):231-7
Publication Type
Article
Date
1992
Author
A M Wiktorsson
T. Martinsson
M. Zimmerman
Author Affiliation
Department of Cariology, Karolinska Institute, Huddinge, Sweden.
Source
Swed Dent J. 1992;16(6):231-7
Date
1992
Language
English
Publication Type
Article
Keywords
Adult
Buffers
Dental Caries - microbiology - prevention & control
Female
Fluoridation
Humans
Lactobacillus - isolation & purification
Male
Regression Analysis
Saliva - chemistry - microbiology - secretion
Sweden - epidemiology
Abstract
In several human studies, scientists have sought to elucidate the connection between caries activity, high levels of lactobacilli, low buffer capacity and a low salivary flow rate, separately or in combinations. The aims of the study were to investigate if there was a difference in caries activity among adults in optimal versus low fluoride areas. It was further investigated if this difference was related to high lactobacilli levels, low buffer capacity and low salivary flow rate, separately or in combination. Finally, it was analysed if the lactobacilli levels were lower in an area with optimal fluoride water concentration. The study is based on clinical examinations of 30-40 year olds who all their lives had drunk water with a fluoride concentration representative for the community. 260 individuals living in the optimal fluoride area and 236 from the low fluoride area are included in the study. The results show a caries activity significantly lower among those in the optimal fluoride area. It is also shown that these differences can not be explained by differences in lactobacilli levels, buffer capacity and salivary flow, neither separately nor in combination. The fluoride concentration in the drinking water is wholly decisive. No difference in lactobacilli levels between optimal and low fluoride areas were demonstrable in this study.
PubMed ID
1481130 View in PubMed
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7 records – page 1 of 1.