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Dermatology screening tools: project update from the GRAPPA 2012 annual meeting.

https://arctichealth.org/en/permalink/ahliterature108291
Source
J Rheumatol. 2013 Aug;40(8):1425-7
Publication Type
Conference/Meeting Material
Date
Aug-2013
Author
Dafna D Gladman
Philip S Helliwell
Majed Khraishi
Kristina Callis Duffin
Philip J Mease
Author Affiliation
University of Toronto, Toronto Western Research Institute, Psoriatic Arthritis Program, University Health Network, Toronto, Ontario, Canada. dafna.gladman@utoronto.ca
Source
J Rheumatol. 2013 Aug;40(8):1425-7
Date
Aug-2013
Language
English
Publication Type
Conference/Meeting Material
Keywords
Arthritis, Psoriatic - diagnosis
Dermatology - trends
Humans
Mass Screening - methods
Prevalence
Psoriasis - diagnosis
Questionnaires
Reproducibility of Results
Sensitivity and specificity
Sweden
Abstract
Several screening tools for early identification of psoriatic arthritis (PsA) have been developed. While these tools had high sensitivity and specificity during their development and initial validation, it remained to be determined how they would function with widespread use. At the 2012 annual meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) in Stockholm, Sweden, these tools were compared for their utility when used to screen patients for PsA in clinics other than those in which they were developed. The screening tools did not perform as well as previously published, and members suggested new tools may need to be developed. An additional study of the prevalence of PsA in a large cohort of psoriasis patients, the PREPARE study, which investigated the use of screening questionnaires, was also presented.
PubMed ID
23908538 View in PubMed
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Ultrasound imaging module: report from the GRAPPA 2012 annual meeting.

https://arctichealth.org/en/permalink/ahliterature108286
Source
J Rheumatol. 2013 Aug;40(8):1450-2
Publication Type
Conference/Meeting Material
Date
Aug-2013
Author
Gurjit S Kaeley
Author Affiliation
Division of Rheumatology, University of Florida College of Medicine, Jacksonville, Florida 32209-6561, USA. drgurj@gmail.com
Source
J Rheumatol. 2013 Aug;40(8):1450-2
Date
Aug-2013
Language
English
Publication Type
Conference/Meeting Material
Keywords
Diagnostic Imaging - methods
Hand Joints - ultrasonography
Humans
Inflammation - diagnosis - ultrasonography
Outcome Assessment (Health Care)
Reproducibility of Results
Sweden
Ultrasonography, Doppler - methods
Abstract
At previous annual meetings of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), members resolved to develop dactylitis and enthesitis ultrasound research projects. Sonography can depict many anatomic alterations in the digits of patients with dactylitis and can also study vascularity of these tissues noninvasively. At the 2012 GRAPPA meeting, the ultrasound workgroup outlined steps in developing a dactylitis outcome measure: determining sonographic elemental lesions; testing to see which of these are the most discriminant in separating dactylitic digits from normal digits; selecting final elements for a sonographic dactylitis index; and conducting validity and reliability testing. A brief update of the enthesitis project was also presented.
PubMed ID
23908544 View in PubMed
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Psoriasis and psoriatic arthritis video project: an update from the 2012 GRAPPA annual meeting.

https://arctichealth.org/en/permalink/ahliterature108284
Source
J Rheumatol. 2013 Aug;40(8):1455-6
Publication Type
Conference/Meeting Material
Date
Aug-2013
Author
Kristina Callis Duffin
April W Armstrong
Philip J Mease
Author Affiliation
University of Utah, Salt Lake City, Utah, USA. Kristina.callis@hsc.utah.edu
Source
J Rheumatol. 2013 Aug;40(8):1455-6
Date
Aug-2013
Language
English
Publication Type
Conference/Meeting Material
Keywords
Arthritis, Psoriatic - diagnosis
Dermatology - education
Humans
Physical Examination - methods
Psoriasis - diagnosis
Reproducibility of Results
Severity of Illness Index
Sweden
Videotape Recording - trends - utilization
Abstract
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) has developed online videos intended to provide training on the most commonly used physical examination measures for psoriasis and psoriatic arthritis (PsA). At the 2012 GRAPPA annual meeting, attendees were updated on the development, availability, use, and validation of these video modules. To date, 1300 users from 45 different countries have used the Psoriasis Area and Severity Index (PASI) module at least once. Results were presented from a recently completed study of pre- and post-video scoring of the PASI by experienced and naive physicians and patient assessors. Future modifications of the video collection were also discussed.
PubMed ID
23908546 View in PubMed
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Assessment of a HER2 scoring system for gastric cancer: results from a validation study.

https://arctichealth.org/en/permalink/ahliterature86032
Source
Histopathology. 2008 Jun;52(7):797-805
Publication Type
Article
Conference/Meeting Material
Date
Jun-2008
Author
Hofmann M.
Stoss O.
Shi D.
Büttner R.
van de Vijver M.
Kim W.
Ochiai A.
Rüschoff J.
Henkel T.
Author Affiliation
Institute of Pathology, Klinikum Kassel, Kassel, Germany.
Source
Histopathology. 2008 Jun;52(7):797-805
Date
Jun-2008
Language
English
Publication Type
Article
Conference/Meeting Material
Keywords
Adenocarcinoma - classification - metabolism
Consensus
Humans
Immunohistochemistry - methods
In Situ Hybridization, Fluorescence - methods
Receptor, erbB-2 - metabolism
Reproducibility of Results
Stomach Neoplasms - classification - metabolism
Tumor Markers, Biological - metabolism
Abstract
AIMS: Human epidermal growth factor receptor 2 (HER2) overexpression/amplification is implicated in the development of various solid tumour types. Validated methods and scoring systems for evaluating HER2 status exist in breast cancer, but not in gastric cancer. The aim was to establish a HER2 scoring system for gastric cancer to identify suitable patients for enrollment in a trial of trastuzumab (Herceptin) in advanced metastatic gastric cancer. METHODS AND RESULTS: Formalin-fixed paraffin-embedded gastric cancer samples were tested for HER2 status using the fluorescence in situ hybridization (FISH) pharmDxt kit (Dako Denmark A/S). Immunohistochemistry (IHC) was performed using the HercepTest (Dako). Concordance between FISH and IHC was 93.5% in 168 evaluable samples. Eleven samples were scored as FISH+ but IHC- or equivocal. CONCLUSIONS: IHC/FISH discrepancies were attributed to basolateral membranous immunoreactivity of glandular cells resulting in incomplete membranous reactivity and/or a higher rate of tumour heterogeneity in gastric cancer compared with breast cancer. With modifications to the IHC scoring system, the HercepTest is considered valid for the identification of HER2+ gastric tumours for this clinical trial. Correlation of HER2 scores with clinical outcomes will be needed to determine which patients might benefit from trastuzumab therapy.
PubMed ID
18422971 View in PubMed
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Development of simple clinical criteria for the definition of inflammatory arthritis, enthesitis, dactylitis, and spondylitis: a report from the GRAPPA 2012 annual meeting.

https://arctichealth.org/en/permalink/ahliterature108287
Source
J Rheumatol. 2013 Aug;40(8):1442-5
Publication Type
Conference/Meeting Material
Date
Aug-2013
Author
Philip J Mease
Amit Garg
Dafna D Gladman
Philip S Helliwell
Author Affiliation
Seattle Rheumatology Associates, Seattle, WA 98122, USA. pmease@philipmease.com
Source
J Rheumatol. 2013 Aug;40(8):1442-5
Date
Aug-2013
Language
English
Publication Type
Conference/Meeting Material
Keywords
Arthritis - diagnosis
Arthritis, Psoriatic - diagnosis
Diagnosis, Differential
Evidence-Based Practice
Hand Joints
Humans
Inflammation - diagnosis
Reproducibility of Results
Rheumatic Diseases - diagnosis
Spondylitis - diagnosis
Sweden
Terminology as Topic
Abstract
Dermatologist and primary care clinicians are in an ideal position to identify the emergence of psoriatic arthritis (PsA) in patients with psoriasis. Yet these clinicians are not well trained to distinguish inflammatory musculoskeletal disease from other more common problems such as osteoarthritis, traumatic or degenerative tendonitis and back pain, or fibromyalgia. A simple set of clinical criteria to identify inflammatory disease would aid recognition of PsA. At its 2012 annual meeting, the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) discussed development of evidence-based, practical, and reliable definitions of inflammatory arthritis, enthesitis, dactylitis, and spondylitis. This project will be a sequential process of expert clinician nominal-group technique, patient surveys and focus groups, and Delphi exercises to identify core features of inflammatory disease, testing these in a small group of patients with and without inflammatory disease, and finally validating these criteria in larger groups of patients.
PubMed ID
23908542 View in PubMed
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Nordic flow cytometry standards for CD34+ cell enumeration in blood and leukapheresis products: report from the second Nordic Workshop. Nordic Stem Cell Laboratory Group (NSCL-G).

https://arctichealth.org/en/permalink/ahliterature22606
Source
J Hematother. 1996 Jun;5(3):237-45
Publication Type
Conference/Meeting Material
Date
Jun-1996
Author
H E Johnsen
L M Knudsen
Author Affiliation
Department of Haematology, Herlev Hospital University of Copenhagen, Denmark.
Source
J Hematother. 1996 Jun;5(3):237-45
Date
Jun-1996
Language
English
Publication Type
Conference/Meeting Material
Keywords
Antigens, CD34 - analysis
Comparative Study
Flow Cytometry - methods - standards
Hematopoietic Stem Cell Transplantation - standards
Humans
Laboratories - standards
Leukapheresis - standards
Leukocyte Count
Reproducibility of Results
Scandinavia
Stem Cells - immunology
Abstract
Recently, Nordic protocols have been activated for the use of high-dose chemotherapy and radiotherapy to treat newly diagnosed young patients with multiple myeloma, breast cancer, and malignant lymphomas. The protocols include transplantation of autologous stem cells or progenitors as supportive therapy. This requires a safe number and optimal quality of the harvested cells. Consequently, the Nordic stem cell laboratories established a collaboration to optimize enumeration of CD34+ cells by flow cytometry. In the first workshop (WS-I) report, we addressed the issue of standardization of technical variables. Taking into consideration the variations in estimation of progenitors, a safe graft should contain > 2.0 x 10(6) CD34+ cells per kilogram patient weight, harvested by two or three leukaphereses. This report presents the results from the second workshop (WS-II). Twelve blood or leukapheresis products were shipped and analyzed in 24 stem cell laboratories, and all results were returned to a central database at Herlev Hospital, Copenhagen. The data documented a significant correlation between CD34+ cell enumerations of the 12 samples analyzed in each of the 24 different stem cell laboratories within the Nordic stem cell laboratory group (NSCL-G). At a practical workshop, the NSCL-G developed a standard for the performance of CD34 enumeration. This is based on the simple Milan Protocol, which uses the anti-HPCA-2PE marking of CD34+ (FL-2) nongranulated (lowSSC) cells. The NSCL-G has decided to hold a third workshop (WS-III) to establish working recommendations for double marking of CD34+ lineage-specific subsets and for handling cellular material for storage of RNA and DNA from blood and leukapheresis products.
PubMed ID
8817390 View in PubMed
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Technical aspects of neonatal screening using tandem mass spectrometry. Report from the 4th meeting of the International Society for Neonatal Screening.

https://arctichealth.org/en/permalink/ahliterature58814
Source
Acta Paediatr Suppl. 1999 Dec;88(432):52-4
Publication Type
Conference/Meeting Material
Article
Date
Dec-1999
Author
H. Simonsen
U G Jensen
Author Affiliation
Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark. hss@ssi.dk
Source
Acta Paediatr Suppl. 1999 Dec;88(432):52-4
Date
Dec-1999
Language
English
Publication Type
Conference/Meeting Material
Article
Keywords
Amino Acid Metabolism, Inborn Errors - diagnosis
Biomedical Technology
Denmark
Female
Humans
Infant, Newborn
Male
Neonatal Screening - methods - standards
Reproducibility of Results
Sensitivity and specificity
Societies, Medical
Spectrum Analysis, Mass - methods
Abstract
Quantitative analysis of amino acids (AA) and acylcarnitines using tandem mass spectrometry is an emerging technology used to screen neonatal dried blood spot samples for disorders in the metabolism of AA, organic acids and fatty acids. This paper provides a brief review of some of the technically oriented issues which emerged at the 4th meeting of the International Society for Neonatal Screening in Stockholm, 1999. The information covers sample preparation, instrumentation, data acquistion modes, internal standards, interpretation, confounding factors and practical screening experience.
PubMed ID
10626579 View in PubMed
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A comparison of the reliability and validity of 3 occlusal indexes of orthodontic treatment need.

https://arctichealth.org/en/permalink/ahliterature193287
Source
Am J Orthod Dentofacial Orthop. 2001 Sep;120(3):240-6
Publication Type
Article
Conference/Meeting Material
Date
Sep-2001
Author
F M Beglin
A R Firestone
K W Vig
F M Beck
R A Kuthy
D. Wade
Author Affiliation
College of Dentistry, Columbus, OH 43218-2357, USA.
Source
Am J Orthod Dentofacial Orthop. 2001 Sep;120(3):240-6
Date
Sep-2001
Language
English
Publication Type
Article
Conference/Meeting Material
Keywords
California
Dental Health Surveys
Esthetics, Dental
Health services needs and demand
Humans
Malocclusion - diagnosis - epidemiology
Observer Variation
ROC Curve
Reproducibility of Results
Sensitivity and specificity
Severity of Illness Index
Sweden
World Health Organization
Abstract
Several occlusal indexes are currently used to ascertain eligibility for orthodontic treatment. A comparison of 3 indexes of orthodontic treatment need was made with the consensus opinion of a panel of 15 experienced orthodontists. Sets of study casts (170) representing the full spectrum of malocclusions were selected. An examiner, calibrated in the Dental Aesthetic Index, the Handicapping Labiolingual Deviation with the California Modification, and the Index of Orthodontic Treatment Need, scored the casts. The panel of orthodontists individually rated the same casts for their degree of orthodontic treatment need. The mean rating of the panel on the need for treatment was used as the gold standard for evaluating the validity of the indexes. Intrarater and interrater reliability was high (kappa > 0.8). Overall accuracy of the indexes, as reflected in area under receiver-operating characteristic curves, was also high: Dental Aesthetic Index, 95%; Handicapping Labiolingual Deviation with the California Modification, 94%; and Index of Orthodontic Treatment Need, 98%. Cutoff points for the indexes that resulted in the closest agreement with the gold standard differed from the published cutoff points for the indexes. The indexes appear to be valid measures of treatment need as perceived by orthodontists. The published cutoff points for the indexes were more conservative in assigning patients for treatment than a panel of orthodontists. However, adjusting the cutoff points moved all 3 indexes into close agreement with the experts.
Notes
Comment In: Am J Orthod Dentofacial Orthop. 2002 Mar;121(3):12A11941333
PubMed ID
11552122 View in PubMed
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Standards for polysomnography in Canada. The Standards Committees of the Canadian Sleep Society and the Canadian Thoracic Society.

https://arctichealth.org/en/permalink/ahliterature210342
Source
CMAJ. 1996 Dec 15;155(12):1673-8
Publication Type
Conference/Meeting Material
Article
Date
Dec-15-1996
Author
C F George
Author Affiliation
University of Western Ontario, London.
Source
CMAJ. 1996 Dec 15;155(12):1673-8
Date
Dec-15-1996
Language
English
Publication Type
Conference/Meeting Material
Article
Keywords
Calibration
Canada
Cardiopulmonary Resuscitation
Certification
Education, Medical, Continuing
Facility Design and Construction
Humans
Medical Laboratory Science - standards
Physician Executives - education - standards
Polysomnography - standards
Quality Control
Reproducibility of Results
Research Design - standards
Sleep Disorders - diagnosis - therapy
Societies, Medical
Abstract
To develop standards for polysomnography in Canada in order to assist in the uniform provision of diagnostic and therapeutic services related to sleep disorders.
Uniform testing versus no current Canadian standards.
Uniform delivery of health care; reduction in number of repeat studies and their attendant costs.
Availability of diagnostic laboratories and services, and survey responses (written and oral) from directors of sleep laboratories; the American Thoracic Society statement on indications and standards for cardiopulmonary sleep studies was used as a template.
Acceptable standards of practice were based on consensus opinion of the standards committees of the Canadian Sleep Society and the Canadian Thoracic Society. The committees comprised specialists in neurology, psychiatry, psychology, respirology and polysomnographic technology; family practitioners and otolaryngologists were also consulted. BENEFITS, HARMS, COSTS: Improved level of care and reduction in duplicate or unnecessary testing; establishment, with available resources, of diagnostic sleep laboratories by appropriately qualified physicians in areas where polysomnography is unavailable.
Health care practitioners involved in the diagnosis and treatment of sleep disorders should possess a minimum amount of training (both clinical and research) in sleep disorders medicine. The variables recorded and findings entered in a patient's report must be relevant to the sleep disorder under investigation. The recording equipment must provide reliable, accurate and reproducible data and lend itself to appropriate calibration and quality-control procedures. Facilities for sleep studies must meet patient care safety standards, with provisions for emergency or resuscitative measures when necessary; all personnel must be trained in basic cardiopulmonary resuscitation.
No previous standards concerning polysomnography in Canada exist. The recommended standards were reviewed by all members of the Canadian Sleep Society and a revised document was approved by the Standards Committee of the Canadian Sleep Society and by the Standards and Executive committees of the Canadian Thoracic Society.
These standards are endorsed by the Canadian Sleep Society and the Canadian Thoracic Society. The cost of preparing this statement was borne by the individual members of the standards committees; no external funding was provided.
Notes
Cites: Electroencephalogr Clin Neurophysiol. 1982 Jun;53(6):658-616177511
Cites: Sleep. 1986 Dec;9(4):519-243809866
Cites: Chest. 1992 Apr;101(4):898-9021555459
Cites: CMAJ. 1986 Apr 1;134(7):721-33948088
Comment In: CMAJ. 1997 May 15;156(10):13799164388
Comment In: CMAJ. 1996 Dec 15;155(12):1693-48976335
PubMed ID
8976332 View in PubMed
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12 records – page 1 of 2.