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Living alone and antidepressant medication use: a prospective study in a working-age population.
BMC Public Health. 2012;12:236
Publication Type
Laura Pulkki-Råback
Mika Kivimäki
Kirsi Ahola
Kaisla Joutsenniemi
Marko Elovainio
Helena Rossi
Sampsa Puttonen
Seppo Koskinen
Erkki Isometsä
Jouko Lönnqvist
Marianna Virtanen
Author Affiliation
Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, 00250 Helsinki, Finland.
BMC Public Health. 2012;12:236
Publication Type
Age Distribution
Antidepressive Agents - therapeutic use
Cluster analysis
Drug Utilization
Educational Status
Employment - psychology
Follow-Up Studies
Health Behavior
Marital status
Middle Aged
Prospective Studies
Psychosocial Deprivation
Regression Analysis
Residence Characteristics - statistics & numerical data
Socioeconomic Factors
An increasing proportion of the population lives in one-person households. The authors examined whether living alone predicts the use of antidepressant medication and whether socioeconomic, psychosocial, or behavioral factors explain this association.
The participants were a nationally representative sample of working-age Finns from the Health 2000 Study, totaling 1695 men and 1776 women with a mean age of 44.6 years. In the baseline survey in 2000, living arrangements (living alone vs. not) and potential explanatory factors, including psychosocial factors (social support, work climate, hostility), sociodemographic factors (occupational grade, education, income, unemployment, urbanicity, rental living, housing conditions), and health behaviors (smoking, alcohol use, physical activity, obesity), were measured. Antidepressant medication use was followed up from 2000 to 2008 through linkage to national prescription registers.
Participants living alone had a 1.81-fold (CI = 1.46-2.23) higher purchase rate of antidepressants during the follow-up period than those who did not live alone. Adjustment for sociodemographic factors attenuated this association by 21% (adjusted OR = 1.64, CI = 1.32-2.05). The corresponding attenuation was 12% after adjustment for psychosocial factors (adjusted OR = 1.71, CI = 1.38-2.11) and 9% after adjustment for health behaviors (adjusted OR = 1.74, CI = 1.41-2.14). Gender-stratified analyses showed that in women the greatest attenuation was related to sociodemographic factors and in men to psychosocial factors.
These data suggest that people living alone may be at increased risk of developing mental health problems. The public health value is in recognizing that people who live alone are more likely to have material and psychosocial problems that may contribute to excess mental health problems in this population group.
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PubMed ID
22443226 View in PubMed
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