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Marriage and divorce among childhood cancer survivors.

https://arctichealth.org/en/permalink/ahliterature131063
Source
J Pediatr Hematol Oncol. 2011 Oct;33(7):500-5
Publication Type
Article
Date
Oct-2011
Author
Susanne Vinkel Koch
Anne Mette Tranberg Kejs
Gerda Engholm
Henrik Møller
Christoffer Johansen
Kjeld Schmiegelow
Author Affiliation
Section of Pediatric Hematology and Oncology, Pediatric Clinic II, Juliane Marie Center, University Hospital, Rigshospitalet and Institute of Gynecology, Obstetrics and Pediatrics, Medical Faculty, University of Copenhagen, Copenhagen, Denmark. susannevinkelkoch@hotmail.com
Source
J Pediatr Hematol Oncol. 2011 Oct;33(7):500-5
Date
Oct-2011
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Central Nervous System Neoplasms - complications - epidemiology - psychology
Child
Child, Preschool
Cognition Disorders - complications - epidemiology - psychology
Cohort Studies
Denmark - epidemiology
Divorce - psychology - statistics & numerical data
Female
Humans
Infant
Infant, Newborn
Male
Marriage - psychology - statistics & numerical data
Neoplasms - complications - epidemiology - psychology
Regression Analysis
Survivors - psychology - statistics & numerical data
Young Adult
Abstract
Many childhood cancer survivors have psychosocial late effects. We studied the risks for cohabitation and subsequent separation. Through the Danish Cancer Register, we identified a nationwide, population-based cohort of all 1877 childhood cancer survivors born from 1965 to 1980, and in whom cancer was diagnosed between 1965 and 1996 before they were 20 years of age. A sex-matched and age-matched population-based control cohort was used for comparison (n=45,449). Demographic and socioeconomic data were obtained from national registers and explored by discrete-time Cox regression analyses. Childhood cancer survivors had a reduced rate of cohabitation [rate ratio (RR) 0.78; 95% confidence interval (CI): 0.73-0.83], owing to lower rates among survivors of both noncentral nervous system (CNS) tumors (RR 0.88; 95% CI: 0.83-0.95) and CNS tumors (RR 0.52; 95% CI: 0.45-0.59). Male CNS tumor survivors had a nonsignificantly lower rate (RR 0.47; 95% CI: 0.38-0.58) than females (RR 0.56; 95% CI: 0.47-0.68). The rates of separation were almost identical to those of controls. In conclusion, the rate of cohabitation was lower for all childhood cancer survivors than for the population-based controls, with the most pronounced reduction among survivors of CNS tumors. Mental deficits after cranial irradiation are likely to be the major risk factor.
PubMed ID
21941142 View in PubMed
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Mobile phones and multiple sclerosis--a nationwide cohort study in Denmark.

https://arctichealth.org/en/permalink/ahliterature124685
Source
PLoS One. 2012;7(4):e34453
Publication Type
Article
Date
2012
Author
Aslak Harbo Poulsen
Egon Stenager
Christoffer Johansen
Joan Bentzen
Søren Friis
Joachim Schüz
Author Affiliation
Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark. Aslak@Cancer.DK
Source
PLoS One. 2012;7(4):e34453
Date
2012
Language
English
Publication Type
Article
Keywords
Cellular Phone
Denmark - epidemiology
Female
Humans
Incidence
Male
Multiple Sclerosis - epidemiology - etiology - mortality
Regression Analysis
Risk factors
Abstract
We investigated the risk of, prognosis of and symptoms of multiple sclerosis (MS) among all Danish residents who owned a mobile phone subscription before 1996. Using the Danish Multiple Sclerosis Registry and Civil Registration System, study subjects were followed up for MS through 2004. Poisson models were used to calculate incidence rate ratios (IRR, age range: 18-64 years) and mortality rate ratios (MRR, age range: 18+) and to compare presenting symptoms among subscribers and all non-subscribers. A total of 405 971 subscription holders accrued four million years of follow up, with men accounting for 86% of the observation time. Among subscription holding men, the IRR of MS was close to unity, overall as well as 13+ years after first subscription (IRR 1.02, 95% CI: 0.48-2.16). Among women, the IRR was 3.43 (95% CI: 0.86-13.72) 13+ years after first subscription, however, based on only two cases. Presenting symptoms of MS differed between subscribers and non-subscribers (p = 0.03), with slightly increased risk of diplopia in both genders (IRR: 1.38, 95% CI: 1.02-1.86), an increased risk of fatigue among women (IRR: 3.02, 95% CI: 1.45-6.28), and of optic neuritis among men (IRR: 1.38, 95% CI: 1.03-1.86). Overall the MRR was close to one (MRR: 0.91, 95%CI 0.70-1.19) among MS-patients with a subscription and although we observed some increased MRR estimates among women, these were based on small numbers. In conclusion, we found little evidence for a pronounced association between mobile phone use and risk of MS or mortality rate among MS patients. Symptoms of MS differed between subscribers and nonsubscribers for symptoms previously suggested to be associated with mobile phone use. This deserves further attention, as does the increased long-term risk of MS among female subscribers, although small numbers and lack of consistency between genders prevent causal interpretation.
Notes
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PubMed ID
22558088 View in PubMed
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Mobile phone use and the risk of skin cancer: a nationwide cohort study in Denmark.

https://arctichealth.org/en/permalink/ahliterature112864
Source
Am J Epidemiol. 2013 Jul 15;178(2):190-7
Publication Type
Article
Date
Jul-15-2013
Author
Aslak Harbo Poulsen
Søren Friis
Christoffer Johansen
Allan Jensen
Patrizia Frei
Susanne Krüger Kjaear
Susanne Oksbjerg Dalton
Joachim Schüz
Author Affiliation
Danish Cancer Society Research Center, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen, Denmark. Aslak@cancer.dk
Source
Am J Epidemiol. 2013 Jul 15;178(2):190-7
Date
Jul-15-2013
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Carcinoma, Basal Cell - epidemiology - etiology
Carcinoma, Squamous Cell - epidemiology - etiology
Cellular Phone - statistics & numerical data - utilization
Denmark - epidemiology
Electromagnetic fields - adverse effects
Female
Follow-Up Studies
Humans
Incidence
Male
Melanoma - epidemiology - etiology
Middle Aged
Models, Statistical
Neoplasms, Radiation-Induced - epidemiology - etiology
Poisson Distribution
Radio Waves - adverse effects
Registries
Regression Analysis
Risk factors
Skin Neoplasms - epidemiology - etiology
Abstract
The International Agency for Research on Cancer has classified radiofrequency radiation as possibly carcinogenic. Previous studies have focused on intracranial tumors, although the skin receives much radiation. In a nationwide cohort study, 355,701 private mobile phone subscribers in Denmark from 1987 to 1995 were followed up through 2007. We calculated incidence rate ratios (IRRs) for melanoma, basal cell carcinoma, and squamous cell carcinoma by using Poisson regression models adjusted for age, calendar period, educational level, and income. Separate IRRs for head/neck tumors and torso/leg tumors were compared (IRR ratios) to further address potential confounders. We observed no overall increased risk for basal cell carcinoma, squamous cell carcinoma, or melanoma of the head and neck. After a follow-up period of at least 13 years, the IRRs for basal cell carcinoma and squamous cell carcinoma remained near unity. Among men, the IRR for melanoma of the head and neck was 1.20 (95% confidence interval: 0.65, 2.22) after a minimum 13-year follow-up, whereas the corresponding IRR for the torso and legs was 1.16 (95% confidence interval: 0.91, 1.47), yielding an IRR ratio of 1.04 (95% confidence interval: 0.54, 2.00). A similar risk pattern was seen among women, though it was based on smaller numbers. In this large, population-based cohort study, little evidence of an increased skin cancer risk was observed among mobile phone users.
PubMed ID
23788669 View in PubMed
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Mortality among participants and non-participants in a prospective cohort study.

https://arctichealth.org/en/permalink/ahliterature119825
Source
Eur J Epidemiol. 2012 Nov;27(11):837-45
Publication Type
Article
Date
Nov-2012
Author
Signe Benzon Larsen
Susanne Oksbjerg Dalton
Joachim Schüz
Jane Christensen
Kim Overvad
Anne Tjønneland
Christoffer Johansen
Anja Olsen
Author Affiliation
Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark. benzon@cancer.dk
Source
Eur J Epidemiol. 2012 Nov;27(11):837-45
Date
Nov-2012
Language
English
Publication Type
Article
Keywords
Age Distribution
Cause of Death
Denmark - epidemiology
Diet
Female
Follow-Up Studies
Health Surveys
Humans
Life Style
Male
Middle Aged
Mortality
Neoplasms - epidemiology
Patient Participation
Population Surveillance
Prospective Studies
Regression Analysis
Risk factors
Sex Distribution
Socioeconomic Factors
Time Factors
Abstract
Socioeconomic position and lifestyle often affect participation in scientific studies. The authors investigated differences in overall and cause-specific mortality between participants and non-participants in the prospective Danish cohort study "Diet, Cancer and Health" and the association between non-participation and mortality by socioeconomic position. A total of 80,996 men and 79,729 women aged 50-64 years, were invited. The authors obtained register data on education, income, death and cause-specific mortality for participants and non-participants and used survival curves to examine differences in overall mortality. Poisson regression models were used to estimate the mortality rate ratio (MRR) by socioeconomic group and by cause of death of participants and non-participants. After a median follow-up of 13 years (5-95 percentiles, 5-14 years), the MRRs for overall mortality among non-participants were 2.09 (95% CI 1.99-2.14) and 2.29 (95% CI 2.19-2.40) among men and women, respectively compared with participants. After adjusting for socioeconomic position, the MRRs changed to 1.73 (95% CI 1.66-1.79) and 2.10 (95% CO 2.01-2.20) among men and women, respectively. The MRRs did not level out after up to 15 years of follow-up. The MRRs were all significantly increased and ranged from 1.51 to 4.28 for men, depending on the cause of death, and from 1.60 to 3.99 for women. Clear differences in mortality from all investigated causes of death were found between participants and non-participants, which persisted after up to 15 years of follow-up. Socioeconomic position had little effect on this result.
PubMed ID
23070658 View in PubMed
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Shaping the Social: design of a settings-based intervention study to improve well-being and reduce smoking and dropout in Danish vocational schools.

https://arctichealth.org/en/permalink/ahliterature268725
Source
BMC Public Health. 2015;15:568
Publication Type
Article
Date
2015
Author
Susan Andersen
Janne Schurmann Tolstrup
Morten Hulvej Rod
Annette Kjær Ersbøll
Betina Bang Sørensen
Teresa Holmberg
Christoffer Johansen
Christiane Stock
Bjarne Laursen
Line Zinckernagel
Anne Louise Øllgaard
Liselotte Ingholt
Source
BMC Public Health. 2015;15:568
Date
2015
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Denmark
Female
Follow-Up Studies
Humans
Male
Personal Satisfaction
Program Evaluation - methods
Regression Analysis
Schools
Smoking - prevention & control
Social Environment
Student Dropouts
Students
Surveys and Questionnaires
Vocational Education
Young Adult
Abstract
The social environment at schools is an important setting to promote educational attainment, and health and well-being of young people. However, within upper secondary education there is a need for evidence-based school intervention programmes. The Shaping the Social intervention is a comprehensive programme integrating social and educational activities to promote student well-being and reduce smoking and dropout in upper secondary vocational education. The evaluation design is reported here.
The evaluation employed a non-randomised cluster controlled design, and schools were selected to either implement the intervention or continue with normal practice for comparison. In the baseline survey conducted 2011-2012, 2,329 students from four intervention schools and 3,371 students from six comparison schools answered a computer-based questionnaire during class, representing 73% and 81% of eligible students, and 22% of all technical/agricultural vocational schools in Denmark. Follow-up assessment was conducted 10 weeks after baseline and at the same time teachers of the intervention classes answered a questionnaire about implementation. School dropout rates will be tracked via national education registers through a 2-year follow-up period.
Shaping the Social was designed to address that students at Danish vocational schools constitute a high risk population concerning health behaviour as well as school dropout by modifying the school environment, alongside developing appropriate evaluation strategies. To address difficulties in implementing settings-based interventions, as highlighted in prior research, the strategy was to involve intervention schools in the development of the intervention. Baseline differences will be included in the effectiveness analysis, so will the impact of likely mediators and moderators of the intervention.
ISRCTN57822968. Date of registration: 16/01/2013.
Notes
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PubMed ID
26088693 View in PubMed
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Socioeconomic position and stage at diagnosis of head and neck cancer - a nationwide study from DAHANCA.

https://arctichealth.org/en/permalink/ahliterature266890
Source
Acta Oncol. 2015 May;54(5):759-66
Publication Type
Article
Date
May-2015
Author
Maja Halgren Olsen
Charlotte Rotbøl Bøje
Trille Kristina Kjær
Marianne Steding-Jessen
Christoffer Johansen
Jens Overgaard
Susanne Oksbjerg Dalton
Source
Acta Oncol. 2015 May;54(5):759-66
Date
May-2015
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell - diagnosis - pathology
Comorbidity
Denmark
Educational Status
Female
Head and Neck Neoplasms - diagnosis - pathology
Humans
Hypopharyngeal Neoplasms - diagnosis - pathology
Income
Male
Marital status
Middle Aged
Neoplasm Staging
Odds Ratio
Oropharyngeal Neoplasms - diagnosis - pathology
Regression Analysis
Sex Factors
Socioeconomic Factors
Urbanization
Abstract
Socioeconomic differences in survival after head and neck squamous cell carcinoma (HNSCC) are among the greatest for any malignancy. To improve our understanding of the mechanisms by which socioeconomic position influences HNSCC survival, we investigated the association between socioeconomic position and advanced stage HNSCC at diagnosis.
Men and women with HNSCC diagnosed between 1992 and 2008 were identified in the Danish Head and Neck Cancer Group (DAHANCA) database, which contains detailed information on all cases of HNSCC treated in Denmark. Individual information on the following four socioeconomic indicators: highest attained educational level, cohabitation status, disposable income and degree of urbanisation were obtained from Statistics Denmark. For the 9683 cases on which there was full information, we estimated odds ratios (ORs) for a diagnosis of advanced stage (TNM III-IV) HNSCC in multivariate logistic regression models by site (glottic, non-glottic larynx, oropharynx, hypopharynx and oral cancer), with adjustment for age, gender, period of diagnosis, education, income, cohabitation status, degree of urbanisation and comorbidity in accordance with a causal diagram.
For all HNSCC sites, the ORs for advanced stage at diagnosis were increased for patients with low income and for men living alone. For glottic and oral cancers, the ORs for advanced stage HNSCC increased systematically by decreasing length of education. Increased ORs were found for hypopharynx cancer patients living in rural areas or provincial cities. Having one or more comorbid conditions was associated with an increased OR for advanced stage oral cancer but with a decreased OR for oropharynx cancer.
In this nationwide population-based study, socioeconomic differences in stage at diagnosis were found for all HNSCC subsites. Focus on the high risk for advanced stage HNSCC among vulnerable patients may be beneficial during referral and diagnosis in order to improve HNSCC outcomes.
PubMed ID
25734503 View in PubMed
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Trajectories of distress, anxiety, and depression among women with breast cancer: Looking beyond the mean.

https://arctichealth.org/en/permalink/ahliterature266882
Source
Acta Oncol. 2015 May;54(5):789-96
Publication Type
Article
Date
May-2015
Author
Pernille Envold Bidstrup
Jane Christensen
Birgitte Goldschmidt Mertz
Nina Rottmann
Susanne Oksbjerg Dalton
Christoffer Johansen
Source
Acta Oncol. 2015 May;54(5):789-96
Date
May-2015
Language
English
Publication Type
Article
Keywords
Adaptation, Psychological
Adult
Aged
Aged, 80 and over
Antineoplastic Agents - administration & dosage
Anxiety - diagnosis
Breast Neoplasms - psychology - therapy
Denmark
Depression - diagnosis
Educational Status
Female
Humans
Marital status
Middle Aged
Postoperative Period
Preoperative Period
Questionnaires
Radiotherapy
Referral and Consultation - statistics & numerical data
Regression Analysis
Social Support
Stress, Psychological - diagnosis - epidemiology
Abstract
Little is known about the development of psychological wellbeing over time among women who have been treated for breast cancer. The aim of this study was to identify distinct patterns of distress, anxiety, and depression in such women.
We invited 426 consecutive women with newly diagnosed primary breast cancer to participate in this study, and 323 (76%) provided information on distress ('distress thermometer') and on symptoms of anxiety and depression ('hospital anxiety and depression scale'). Semiparametric group-based mixture modeling was used to identify distinct trajectories of distress, anxiety, and depressive symptoms assessed the week before surgery and four and eight months later. Logistic regression analysis was used to evaluate the characteristics of women in the distinct groups.
Although no sub-group of women with chronic severe anxiety or depressive symptoms was found, we did identify a sub-group of 8% of the women who experienced continuously severe distress. Young age, having a partner, shorter education, and receiving chemotherapy but not radiotherapy might characterize women whose psychological symptoms remain strong eight months after diagnosis.
By looking beyond the mean, we found that 8% of the women experienced chronic severe distress; no sub-groups with chronic severe anxiety or depression were identified. Several socio-demographic and treatment factors characterized the women whose distress level remained severe eight months after diagnosis. The results suggest that support could be focused on relatively small groups of patients most in need.
PubMed ID
25761086 View in PubMed
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7 records – page 1 of 1.