A non-loading pneumocalorimetric mode of quantitative assessment of physical performance (PP) has been developed in a series of 25 essentially healthy subjects. Based on the correlation-and-regression analysis a formula for PP was found out to be PP = 59.9 x MCC + 33, were MCC is maximum caloric capacity. PP quantitative assessment was proved to be effective in patients presenting with cardiopulmonary problems.
Examination of 163 schoolboys in higher forms has revealed that strength of the nervous system and functional state of the CNS (functional level of the system, level of functional possibilities, arousal and reaction stability) do not differ in schoolchildren with various progress in learning. The school teaching efficiency correlated with parameters of strength of the nervous system only in excellent and good pupils, the functional state of the nervous system being of importance for their teaching, especially its such parameters as arousal, level of functional possibilities and reaction stability. In pupils with poor progress those correlations were absent.
Clinical, instrumental, laboratory and neuropsychological examinations were performed in 79 patients with essential hypertension (EH). It was found using multiple linear regression analysis that significant predictors of cerebral disorders in patients with EH are elevated maximum values of systolic blood pressure (BP) according anamnesis data, increased intima-media thickness, increased mean daytime diastolic BP load values, increased average daytime mean BP values, increased maximum 24-hours mean BP values, increased pulse pressure variability by ambulatory BP monitoring, elevated levels of total cholesterol, a lower educational level, a greater age of patients and worsening of subjective stress assessment.
A comparative analysis of different statistic methods for determining individual reactivity of the respiratory system has been made. A mathematical model of ventilation dependence on partial pressure of carbon dioxide has been suggested. It has essential advantage as compared to those used before.
A retrospective analysis was carried out of an 8-year survival in a series of 410 patients presenting with stage I-II breast cancer. Results are assessed of different combinations of a multiple-modality treatment involving surgical, chemotherapeutical, radiation, and hormonal methods. It is pointed out that adjuvant chemotherapy can make the results better. Other methods do not exert statistically significant effect on survival of patients.
An analysis was performed of comprehensive (non-invasive and invasive) observations of IHD patients presenting with atherosclerotic lesions of coronary arteries of the heart and atypical clinical picture of the condition. A possibility was shown of a significant obstruction of arteries of the heart in atypical localization of pain and in those patients who had not derived much benefit from nitroglycerin during the development of ischemia and measures instituted against it. Inadequate reaction to nitroglycerin may be explained by specificities of changes in the vegetative nervous system, by the hemodynamics reaction, and, in the first place, by a propensity for developing tachycardia under physical loading, emotional stress, and after ingestion of nitroglycerin.
For all breakthroughs in the treatment of cancer of the uterine cervix diagnosis of the incipient stages of malignancy still poses unique problems. The studies made on the basis of the clinical hospital N 16 and the Oncologic Centre of the Ministry of Health of Ukraine, histological investigations conducted on the basis of the clinical hospital N 25 and the Ukraine MH Oncological Centre permitted the examination of 209 women who had applied for medical advice for background and pretumour disorders of the neck of the womb. On having done the statistical processing of data, analysis of the secured findings was performed. The choice of the relevant method and theoretical preparation for the regression analysis were put through as recommended by Lakin G. F. Thus, the uterine cervix background and pretumour morbidity has two age peaks of different degree: the first--the main peak--falls on age 25, the second peak--that of a weaker degree--falls on age 38 years. The above two peaks fall on the active reproductive period of life (25 to 40 years of age)--just that time in women's life during which high case rates are recordable with background and pretumour pathology.
General properties of cardiovascular system functioning in the groups of postoperative patients in the cardiac surgery clinic were studied using the information technology (IT), combined the methods of cluster and nonlinear regression analysis and computer simulation. It was shown, that in all five separated groups of observations (clusters) the direct dependency of cardiac (CI) and stroke (SI) indexes on central venous pressure (CVP) was determined by the variations of total peripheral resistance and reactions of venous tone (u), contractility (E) and heart rate (HR), oriented on the stabilisation of mean aortic pressure (AP) on approximately the same level. Significant differences between the characteristics CI(CVP), SI(CVP) in the groups were determined by the level of E (especially of the right ventricle) and diastolic tone of the heart. Correlation of the cardiac (E,HR) and vascular (u) components of Ap regulation changed correspondingly the heart functional state. Proposed approach and IT may be used in such clinical and experimental research where considerable volume of observations is combined with the great variation of data and, correspondingly, a poor definition level of system behavior.
