A total of 866 patients with chronic unspecific lung diseases were examined. Medical data collection, storage and acquisition involved making use of the operational system UNIX as well as data base control systems UBASE and INFORMIX. Relation was found out between use rate of bronchodilators, antibacterial drugs, corticosteroids, and results of treatment. The above patients can also derive benefit from such nonpharmacologic modes of treatment as apparatus-aided training of breathing, hypoxia and hypercapnia training, acupuncture-laser therapy treatments, herbal aromatic substances.
The authors discuss the problem of selective derivation of the genetic material of spermatozoa for molecular genetic identification from mixed biological traces containing sperm on material evidence. Possible methods of improving the efficacy of differential lysis of cells present in mixed traces are analyzed. Effects of some routinely used extractants on biological substrata, most often contaminating the sperm in expert material, have been studied, and conditions for their most complete elimination from objects of investigation optimized.
The authors elaborated a medical and ecologic questionnaire for specific history. The questionnaire was applied to express-evaluation of public health state and environmental factors in the certain settlement. The health state was proved to be influenced significantly by occupational conditions, hardiness and intensity of work, psychologic climate. The most hazardous environmental factors are: unsatisfactory quality of drinkable water, air pollution and traffic noise. The lifestyle of the population examined is strongly associated with bad habits (smoking, short sleep, alcohol abuse).
Occurrence of benign tumors in large pediatric population have never been studied. Basing on the data on the pediatric population of Khabarovsk, the authors developed a method of improved analysis of benign tumor morbidity. The method suggests the use of case histories as well as medical check-up data. Mathematical modelling was employed to compare primary incidence and occurrence indexes. The improved mean incidence of benign tumors in children for 1985-1989 was 66.8 cases and improved occurrence--174.2 per 10,000 children. The values are by the order of magnitude higher than those reported by hospitals.
A representative population sample was studied to elucidate relationships of arterial pressure (AR) with muscular performance (MP) and arterial hypertension risk factors. Power working capacity (PWCx) was measured by means of exercise tolerance test at rest, under physical loading and after the exercise. The findings were processed using a multivariate step-by-step regression analysis which established independent relations between exercise and postexercise MP and arterial hypertension. In normal and hypertensive males a rise in systolic pressure (SP) after the initial exercise (load 1) was dependent on PWC1 after more intensive exercise (load 2) on relations of MP with heart rate, SP and diastolic pressure (DP). In hypertensive males the SP elevation depended also on the age, B. W. index and heart rate. In normal AP males a DP rise depended on PWC2 and MP, the increment being limited by relationships between MP, DP, heart rate and SP. In hypertensive males the influence of PWC1 is defined through a SP rise after load 1. In normal AP and hypertensive females PWC1 is decisive for a SP rise. In normal AP females growth of DP after load 2 was dependent on PWC2 in relation to heart rate growth after load 2, while in hypertensive females PWC1 resulted in DP elevation after load 1. On comparison of the groups with normal and high AP the degree of AP increment under exercise depended on the relations of MP with heart rate, SP and DP.
THE THEME: assessment of the influence of socio-economic factors on health and demographic indicators.
population of municipalities of the Voronezh region.
the justification of the system of measures aimed at stabilizing the medical-demographic situation at the regional level.
methods of Health Statistics; questionnaire.
the low socio-economic status of the population is set in the territories, depressed at the level of demographic development. The contribution of socio-economic indicators in health and demographic situation has been determined Reliable cause-effect relationships between health and demographic indicators and the level of socio-economic development of the population have been identified.
The article presents results obtained in study of relationship between polymorph variants of CYP1A1 and CYP1A2 genes with reproductive and thyroid diseases risk in female workers of petrochemical industry, when compared with reference group females. Variants TD and DD of CYP1A2 gene appeared to be associated with nodes formation in uterus and breast in female workers and reference group females. Following liability markers are obtained: homozygous in rare allele genotype CC of CYP1A1 gene for reproductive and thyroid diseaes (fibrous cystic mastopathy and nodular goitre), heterozygous genotype AG of CYP1A1 gene in uterine myoma and fibrous cystic mastopathy, homozygous in deleted T genotype of CYP1A2 gene in autoimmune thyroiditis. Occupational hazards and long length of service at hazardous industries increase effects of rare alleles of the genes studied.