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In response to the article "The prevention and management of acute skin reactions related to radiation therapy: a systematic review and practice guideline" (Bolderston et al. 2006).

https://arctichealth.org/en/permalink/ahliterature164556
Source
Support Care Cancer. 2007 Oct;15(10):1219; author reply 1221
Publication Type
Article
Date
Oct-2007
Author
Kelly Nystedt
Source
Support Care Cancer. 2007 Oct;15(10):1219; author reply 1221
Date
Oct-2007
Language
English
Publication Type
Article
Keywords
British Columbia
Humans
Practice Guidelines as Topic
Radiodermatitis - prevention & control - therapy
Radiotherapy - adverse effects
Skin - pathology - radiation effects
Notes
Comment On: Support Care Cancer. 2006 Aug;14(8):802-1716758176
PubMed ID
17372772 View in PubMed
Less detail

The prevention and management of acute skin reactions related to radiation therapy: a systematic review and practice guideline.

https://arctichealth.org/en/permalink/ahliterature168941
Source
Support Care Cancer. 2006 Aug;14(8):802-17
Publication Type
Article
Date
Aug-2006
Author
Amanda Bolderston
Nancy S Lloyd
Rebecca K S Wong
Lori Holden
Linda Robb-Blenderman
Author Affiliation
Department of Radiation Oncology, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada.
Source
Support Care Cancer. 2006 Aug;14(8):802-17
Date
Aug-2006
Language
English
Publication Type
Article
Keywords
Acute Disease
Bandages
Baths - methods
Clinical Trials as Topic
Dermatologic Agents - therapeutic use
Evidence-Based Medicine
Humans
Neoplasms - radiotherapy
Ontario
Radiodermatitis - prevention & control - therapy
Radiotherapy, Adjuvant - adverse effects
Steroids - therapeutic use
Abstract
To develop a practice guideline report on the questions: What are the optimal methods to prevent acute skin reactions (occurring within the first 6 months of irradiation) related to radiation therapy? What are the optimal methods to manage acute skin reactions related to radiation therapy?
Cancer Care Ontario's Supportive Care Guidelines Group (SCGG) conducted a systematic review of literature on this topic. Evidence-based recommendations were formulated to guide clinical decision making, and a formal external review process was conducted to validate the relevance of these opinions for Ontario practitioners.
Twenty-eight trials meeting the inclusion criteria were identified. Of the twenty-three trials that evaluated preventative methods, washing was the only practice which significantly prevented skin reaction. Some evidence suggested topical steroid creams and calendula ointment might be effective. None of the five trials evaluating skin reaction management detected a positive effect using steroid cream, sucralfate cream, or dressings.
Skin washing, including gentle washing with water alone with or without mild soap, should be permitted in patients receiving radiation therapy to prevent acute skin reaction. There is insufficient evidence to support or refute specific topical or oral agents for the prevention or management of acute skin reaction. In the expert opinion from the SCGG, the use of a plain, non-scented, lanolin-free hydrophilic cream may be helpful in preventing radiation skin reactions. In addition, a low dose (i.e., 1%) corticosteroid cream may be beneficial in the reduction of itching and irritation.
Notes
Comment In: Support Care Cancer. 2007 Oct;15(10):1219; author reply 122117372772
PubMed ID
16758176 View in PubMed
Less detail