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Antibiotic prescriptions and cycles of Mycoplasma pneumoniae infections in Norway: can a nationwide prescription register be used for surveillance?

https://arctichealth.org/en/permalink/ahliterature265198
Source
Epidemiol Infect. 2015 Jul;143(9):1884-92
Publication Type
Article
Date
Jul-2015
Author
H S Blix
D F Vestrheim
V. Hjellvik
D. Skaare
A. Christensen
M. Steinbakk
Source
Epidemiol Infect. 2015 Jul;143(9):1884-92
Date
Jul-2015
Language
English
Publication Type
Article
Keywords
Anti-Bacterial Agents - therapeutic use
Child
Clarithromycin - therapeutic use
Doxycycline - therapeutic use
Drug Prescriptions - statistics & numerical data
Epidemics
Erythromycin - therapeutic use
Humans
Mycoplasma pneumoniae - physiology
Norway - epidemiology
Pneumonia, Mycoplasma - drug therapy - epidemiology - microbiology
Public Health Surveillance
Abstract
Mycoplasma pneumoniae outbreaks cause increased use of macrolides and tetracyclines. We aimed to investigate whether drug use data, in addition to laboratory data, could improve understanding of the spread of M. pneumoniae epidemics. Number of users of Mycoplasma antibiotics (erythromycin, doxycycline, clarithromycin) per week and county of residence in an indicator age group (6-12 years) was retrieved from the Norwegian prescription database for the epidemic season 2011-2012 and compared to non-epidemic seasons. In 2011, increased use of Mycoplasma antibiotics was first observed in September on the west coast of Norway. The Norwegian laboratory-based surveillance system showed the first increase in positive tests in August 2011 and an epidemic was announced on 25 October 2011. At that time the use of Mycoplasma antibiotics had already exceeded three times the use in non-epidemic periods. Data for three counties from the regional microbiological laboratories showed that the increase in number of positive samples coincided in time with the increase in prescription data. Laboratory data cannot accurately determine the extent of an epidemic, and drug use data cannot identify the cause. Establishing a systematic interaction between the two monitoring systems will enhance surveillance and probably contribute to improved infection control and prudent antibiotic prescribing.
Notes
Cites: Euro Surveill. 2012;17(5). pii: 2007522321134
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Cites: Cochrane Database Syst Rev. 2012;9:CD00487522972079
Cites: Euro Surveill. 2012;17(6). pii: 2008222340974
Cites: Infect Control Hosp Epidemiol. 2012 Apr;33(4):322-722418625
PubMed ID
25388750 View in PubMed
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Anxiety symptoms and suicidal feelings in a population sample of 70-year-olds without dementia.

https://arctichealth.org/en/permalink/ahliterature123921
Source
Int Psychogeriatr. 2012 Nov;24(11):1865-71
Publication Type
Article
Date
Nov-2012
Author
Mattias Jonson
Ingmar Skoog
Thomas Marlow
Madeleine Mellqvist Fässberg
Margda Waern
Author Affiliation
Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden.
Source
Int Psychogeriatr. 2012 Nov;24(11):1865-71
Date
Nov-2012
Language
English
Publication Type
Article
Keywords
Age of Onset
Aged
Anxiety - diagnosis - epidemiology - psychology
Cost of Illness
Data Interpretation, Statistical
Depression - diagnosis - epidemiology - psychology
Female
Humans
Interview, Psychological
Male
Psychiatric Status Rating Scales
Public Health Surveillance
Socioeconomic Factors
Suicidal ideation
Sweden - epidemiology
Abstract
The role of anxiety in late-life suicidal behavior has received relatively little attention. The aim was to explore the association between anxiety symptoms and suicidal feelings in a population sample of 70-year-olds without dementia, and to test whether associations would be independent of depression.
Face-to-face interviews (N = 560) were carried out by psychiatric nurses and past month symptoms were rated with the Comprehensive Psychopathological Rating Scale (CPRS). The Brief Scale for Anxiety (BSA) was derived from the CPRS to quantify anxiety symptom burden. Past month suicidal feelings were evaluated with the Paykel questions.
Anxiety symptom burden was associated with suicidal feelings and the association remained after adjusting for major depression. One individual BSA item (Inner tension) was independently associated with suicidal feelings in a multivariate regression model. The association did not remain, however, in a final model in which depression symptoms replaced depression diagnosis.
Results from this population study suggest an association between anxiety and suicidal feelings in older adults. The role of anxiety and depression symptoms needs further clarification in the study of suicidal behavior in late life.
PubMed ID
22647285 View in PubMed
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Assessing the number of fire fatalities in a defined population.

https://arctichealth.org/en/permalink/ahliterature274401
Source
J Safety Res. 2015 Dec;55:99-103
Publication Type
Article
Date
Dec-2015
Author
Anders Jonsson
Anders Bergqvist
Ragnar Andersson
Source
J Safety Res. 2015 Dec;55:99-103
Date
Dec-2015
Language
English
Publication Type
Article
Keywords
Adult
Burns - mortality
Databases, Factual
Female
Fires - statistics & numerical data
Humans
Public Health Surveillance
Sweden - epidemiology
Abstract
Fire-related fatalities and injuries have become a growing governmental concern in Sweden, and a national vision zero strategy has been adopted stating that nobody should get killed or seriously injured from fires. There is considerable uncertainty, however, regarding the numbers of both deaths and injuries due to fires. Different national sources present different numbers, even on deaths, which obstructs reliable surveillance of the problem over time. We assume the situation is similar in other countries. This study seeks to assess the true number of fire-related deaths in Sweden by combining sources, and to verify the coverage of each individual source. By doing so, we also wish to demonstrate the possibilities of improved surveillance practices.
Data from three national sources were collected and matched; a special database on fatal fires held by The Swedish Contingencies Agency (nationally responsible for fire prevention), a database on forensic medical examinations held by the National Board of Forensic Medicine, and the cause of death register held by the Swedish National Board of Health and Welfare.
The results disclose considerable underreporting in the single sources. The national database on fatal fires, serving as the principal source for policy making on fire prevention matters, underestimates the true situation by 20%. Its coverage of residential fires appears to be better than other fires.
Systematic safety work and informed policy-making presuppose access to correct and reliable numbers. By combining several different sources, as suggested in this study, the national database on fatal fires is now considerably improved and includes regular matching with complementary sources.
PubMed ID
26683552 View in PubMed
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The asthma-rhinitis multimorbidity is associated with IgE polysensitization in adolescents and adults.

https://arctichealth.org/en/permalink/ahliterature302557
Source
Allergy. 2018 Jul; 73(7):1447-1458
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Date
Jul-2018
Author
V Siroux
N Ballardini
M Soler
C Lupinek
A Boudier
I Pin
J Just
R Nadif
J M Anto
E Melen
R Valenta
M Wickman
J Bousquet
Author Affiliation
Inserm, CNRS, IAB, University Grenoble Alpes, Grenoble, France.
Source
Allergy. 2018 Jul; 73(7):1447-1458
Date
Jul-2018
Language
English
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Keywords
Adolescent
Adult
Allergens
Asthma - epidemiology - immunology
Comorbidity
Cross Reactions - immunology
Female
Humans
Immunization
Immunoglobulin E - immunology
Male
Middle Aged
Odds Ratio
Phenotype
Public Health Surveillance
Rhinitis - epidemiology - immunology
Sweden - epidemiology
Young Adult
Abstract
Children with multimorbid asthma and rhinitis show IgE polysensitization to several allergen sources. This association remains poorly studied in adolescents and adults using defined allergen molecules. We investigated IgE sensitization patterns towards a broad panel of aeroallergen components in adults and adolescents with a focus on individuals with asthma and rhinitis multimorbidity.
IgE reactivity to 64 micro-arrayed aeroallergen molecules was determined with the MeDALL-chip in samples from the French EGEA study (n = 840, age = 40.7 ± 17.1) and the Swedish population-based birth cohort BAMSE (n = 786, age = 16 ± 0.26). The age- and sex-adjusted associations between the number of IgE-reactive allergen molecules (=0.3 ISU) and the asthma-rhinitis phenotypes were assessed using a negative binomial model.
Groups representing 4 phenotypes were identified: no asthma-no rhinitis (A-R-; 30% in EGEA and 54% in BAMSE), asthma alone (A+R-; 11% and 8%), rhinitis alone (A-R+; 15% and 24%) and asthma-rhinitis (A+R+; 44% and 14%). The numbers of IgE-reactive aeroallergen molecules significantly differed between phenotypes (median in A-R-, A+R-, A-R+ and A+R+: 0, 1, 2 and 7 in EGEA and 0, 0, 3 and 5 in BAMSE). As compared to A-R- subjects, the adjusted ratio of the mean number of IgE-reactive molecules was higher in A+R+ than in A+R- or A-R+ (10.0, 5.4 and 5.0 in EGEA and 7.2, 0.7 and 4.8 in BAMSE).
The A+R+ phenotype combined the sensitization pattern of both the A-R+ and A+R- phenotypes. This multimorbid polysensitized phenotype seems to be generalizable to various ages and allergenic environments and may be associated with specific mechanisms.
PubMed ID
29331026 View in PubMed
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Bodyweight changes are associated with reduced health related quality of life: the Hordaland Health Study.

https://arctichealth.org/en/permalink/ahliterature268810
Source
PLoS One. 2014;9(10):e110173
Publication Type
Article
Date
2014
Author
Gunhild Hervik Thorbjørnsen
Trond Riise
Jannike Øyen
Source
PLoS One. 2014;9(10):e110173
Date
2014
Language
English
Publication Type
Article
Keywords
Adult
Body mass index
Body Weight
Exercise
Female
Health status
Humans
Male
Middle Aged
Norway
Public Health Surveillance
Quality of Life
Smoking
Abstract
There is lack of studies investigating the association between bodyweight changes and health related quality of life (HRQL). The aim was to study the effect of relative changes in bodyweight over time on HRQL. In the Hordaland Health Study, 9276 men and 10433 women aged 40-47 years were included. Weight and height were measured and information on bodyweight changes during the last 5 years, physical activity and smoking was obtained from self-administered questionnaires including the Medical Outcomes Study MOS short form-12 including a Physical health Composite Score (PCS) and a Mental health Composite Score (MCS). Increasing bodyweight changes were associated with marked reduced scores in PCS and MCS also after adjustment for body mass index (BMI), physical activity and smoking. Men and women with a variation in weight with more than 15% during the last 5 years reported a mean score of MCS that was 0.48 standard deviation (SD) (3.9/8.1) and 0.35 SD (3.1/8.9) lower than those reporting a variation in weight less than 5%. No major differences were found between those who at date of examination were at the lower and higher end of the reported weight interval. There were no significant differences in the associations between men and women. Our findings confirm that increasing bodyweight changes are associated with reduced physical and mental health beyond what is related to BMI itself.
Notes
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Cites: Prev Med. 2007 Dec;45(6):401-1517707498
PubMed ID
25303082 View in PubMed
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Breast cancer incidence and menopausal hormone therapy in Norway from 2004 to 2009: a register-based cohort study.

https://arctichealth.org/en/permalink/ahliterature272579
Source
Cancer Med. 2015 Aug;4(8):1303-8
Publication Type
Article
Date
Aug-2015
Author
Pål Suhrke
Per-Henrik Zahl
Source
Cancer Med. 2015 Aug;4(8):1303-8
Date
Aug-2015
Language
English
Publication Type
Article
Keywords
Breast Neoplasms - diagnosis - epidemiology - etiology - history
Female
History, 21st Century
Hormone Replacement Therapy
Humans
Incidence
Mammography
Menopause
Middle Aged
Neoplasm Staging
Norway - epidemiology
Public Health Surveillance
Registries
Risk
Abstract
In Norway, the breast cancer incidence increased by 50% in the 1990 s, during a period with initiation of mammography screening as well as a fourfold increase in use of menopausal hormone therapy (HT). After 2002, the HT use has dropped substantially; however, the breast cancer incidence has declined only marginally. How much mammography screening contributed to the breast cancer incidence increase in the 1990 s compared with HT use and specifically different types of HT use, has thus been discussed. Whether HT affects the incidence of subtypes of breast cancer differently has also been questioned. We have linked individual data from several national registries from 2004 to 2009 on 449,717 women aged 50-65 years. 4597 cases of invasive cancer and 681 cases of ductal carcinoma in situ (DCIS) were included in the analysis. We used Cox regression to estimate hazard ratio (HR) as a measure of the relative risk of breast cancer associated with use of HT. The HRs associated with prescriptions of HT for more than 1 year were 2.06 (1.90-2.24) for estrogen and progesterone combinations, 1.03 (0.85-1.25) for systemic estrogens, and 1.23 (1.01-1.51) for tibolone. Invasive lobular carcinoma was more strongly associated with use of estrogen and progesterone combinations, HR = 3.10 (2.51-3.81), than nonlobular carcinoma, HR = 1.94 (1.78-2.12). The corresponding value for DCIS was 1.61 (1.28-2.02). We estimated the population attributable fraction to 8.2%, corresponding to 90 breast cancer cases in 2006 indicating that HT use still caused a major number of breast cancer cases.
Notes
Cites: Int J Cancer. 2012 Jun 15;130(12):2930-821732346
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PubMed ID
25991514 View in PubMed
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Burden of allergy diets in Finnish day care reduced by change in practices.

https://arctichealth.org/en/permalink/ahliterature287409
Source
Allergy. 2016 Oct;71(10):1453-60
Publication Type
Article
Date
Oct-2016
Author
M. Erkkola
T. Saloheimo
H. Hauta-Alus
A K Kukkonen
S. Virta
C. Kronberg-Kippilä
E. Vaara
A S Pelkonen
M. Fogelholm
M J Mäkelä
Source
Allergy. 2016 Oct;71(10):1453-60
Date
Oct-2016
Language
English
Publication Type
Article
Keywords
Allied Health Personnel
Child
Child Care - statistics & numerical data
Child Day Care Centers - statistics & numerical data
Child, Preschool
Diet - adverse effects
Female
Finland - epidemiology
Food Hypersensitivity - epidemiology
Health Knowledge, Attitudes, Practice
Humans
Infant
Infant, Newborn
Male
Public Health Surveillance
Abstract
Nonessential allergy diets in children with mild symptoms may harm the development of immunological tolerance and impose a burden on families and day care. We aimed to reduce the high prevalence of allergy diets in day care by reforming the practices for inquiring about need of special diets from parents.
We developed a new special diet form and an information leaflet based on the new allergy guidelines. The new form was implemented into 40 Finnish day care centres in the capital region in 2013-2015. The questionnaires on practices concerning special diets in day care centres and allergy knowledge were collected from the personnel.
After 2 years, the new special diet form was used by 64% of families with food-allergic children, and the prevalence of allergy diets in day care centres decreased by 43% to 4.3% (IQ range 3.05-5.96). A significant decrease was found in the prevalence of all basic (milk, grains, egg) and most other allergy diets (P for trend
PubMed ID
27117067 View in PubMed
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Canadian poison control centres: preliminary assessment of their potential as a resource for public health surveillance.

https://arctichealth.org/en/permalink/ahliterature106641
Source
Clin Toxicol (Phila). 2013 Nov;51(9):886-91
Publication Type
Article
Date
Nov-2013
Author
M. Durigon
C. Elliott
R. Purssell
T. Kosatsky
Author Affiliation
Canadian Field Epidemiology Program, Public Health Agency of Canada , Ottawa, ON , Canada.
Source
Clin Toxicol (Phila). 2013 Nov;51(9):886-91
Date
Nov-2013
Language
English
Publication Type
Article
Keywords
Animals
Canada - epidemiology
Capacity Building - economics
Epidemiological Monitoring - veterinary
Government Programs - economics
Health Impact Assessment
Humans
Poison Control Centers - economics - manpower
Poisoning - economics - epidemiology - veterinary
Public Health Surveillance
Questionnaires
Abstract
In the United States (US) and Europe, surveillance based on calls to poison control centres has identified new hazards and evolving exposure trends. In Canada, the value of poison control centre calls as a tool for health hazard surveillance is largely unrecognized.
This preliminary survey was undertaken to describe current operational characteristics and surveillance capacities at Canadian poison control centres and to determine potential for developing a Canadian poison control centre collaborative network.
A structured quantitative-qualitative survey was administered to medical directors and clinical supervisors at the five Canadian poison control centres between March and May, 2012.
All five Canadian poison control centres operate 24/7 with each serving more than one province/territory. Annual call volumes range from 10,000 to 58,000. Data analysis is limited to detection of previously unrecognized hazards and short-term event-based adverse health monitoring. Currently no centre maintains systematic ongoing collection, integration and analysis of data. Constraints on personnel, resources and funding were identified as barriers to increasing capacity to provide and analyse call data.
The potential exists to use Canadian poison control data as a novel source of public health surveillance. That they serve as sentinels for new or unexpected exposure events, have real-time electronic call-record capacity and demonstrate an interest in developing and sharing their call-record information supports their integration into existing public health networks.
PubMed ID
24134535 View in PubMed
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Cesarean section and disease associated with immune function.

https://arctichealth.org/en/permalink/ahliterature273908
Source
J Allergy Clin Immunol. 2016 Feb;137(2):587-90
Publication Type
Article
Date
Feb-2016
Author
Kim Kristensen
Lonny Henriksen
Source
J Allergy Clin Immunol. 2016 Feb;137(2):587-90
Date
Feb-2016
Language
English
Publication Type
Article
Keywords
Adolescent
Cesarean Section - adverse effects
Child
Child, Preschool
Cohort Studies
Delivery, Obstetric
Denmark
Disease Susceptibility - immunology
Female
Humans
Immunity
Infant
Infant, Newborn
Male
Pregnancy
Proportional Hazards Models
Public Health Surveillance
Registries
Risk
Abstract
Earlier studies have shown that delivery by cesarean section (CS) is associated with an increased risk of disease associated with immune function in the offspring, but these studies have generally not discriminated between the effect of acute and elective CS.
We sought to further explore these associations using discrimination between the effects of acute versus elective CS.
We performed a population- and national register-based cohort study including all children born in Denmark from January 1997 through December 2012. Hazard ratios for diseases associated with immune function in children delivered by acute and elective CS with vaginal delivery as the reference were calculated by using Cox regression. All analyses were adjusted for gestational age, sex, birth weight, maternal age, maternal smoking during pregnancy, and complications during pregnancy (preeclampsia, eclampsia, hemorrhage, and hyperemesis).
A total of 750,569 children aged 0 to 14 years were included. Children delivered by both acute and elective CS had an increased risk of asthma, laryngitis, and gastroenteritis. Children delivered by acute CS had an increased risk of ulcerative colitis and celiac disease, whereas children delivered by elective CS had an increased risk of lower respiratory tract infection and juvenile idiopathic arthritis. The effect of elective CS was higher than the effect of acute CS on the risk of asthma.
Children delivered by CS are at increased risk of disease associated with immune function. The effect is mainly on diseases involving the mucosal immune system.
PubMed ID
26371844 View in PubMed
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