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Effects of a large-scale intervention with influenza and 23-valent pneumococcal vaccines in elderly people: a 1-year follow-up.

https://arctichealth.org/en/permalink/ahliterature57424
Source
Vaccine. 2003 Sep 8;21(25-26):3906-11
Publication Type
Article
Date
Sep-8-2003
Author
J. Hedlund
B. Christenson
P. Lundbergh
A. Ortqvist
Author Affiliation
Department of Infectious Diseases, Karolinska Institutet, Karolinska Hospital, S-17176 Stockholm, Sweden. jonas.hedlund@ks.se
Source
Vaccine. 2003 Sep 8;21(25-26):3906-11
Date
Sep-8-2003
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Aging - physiology
Cohort Studies
Endpoint Determination
Female
Hospitalization - statistics & numerical data
Humans
Immunization Programs
Influenza Vaccines - immunology
Influenza, Human - epidemiology - mortality - prevention & control
Male
Pneumococcal Infections - epidemiology - mortality - prevention & control
Pneumococcal Vaccines - immunology
Research Support, Non-U.S. Gov't
Seasons
Sweden - epidemiology
Vaccination
Abstract
To assess the effectiveness of influenza and pneumococcal vaccination in reducing hospitalisation and deaths in elderly people, the population aged > or =65 years in Stockholm County, Sweden (n = 259627) were invited to take part in a vaccination campaign with influenza and 23-valent pneumococcal vaccine (PV). A no. of persons (100,242) (vaccinated cohort) were vaccinated with one or both vaccines during the campaign. The incidence of hospital admissions during 1 year after the vaccination campaign, adjusted for sex and age, was significantly lower in the vaccinated than in the unvaccinated cohort for influenza (relative risk [RR] 0.68), pneumonia (RR 0.78), and invasive pneumococcal disease (RR 0.46). In the vaccinated cohort, the in-hospital mortality was lower for pneumonia (RR 0.55), COPD (RR 0.53) and cardiac failure (RR 0.72).
PubMed ID
12922125 View in PubMed
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