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2470 records – page 1 of 247.

A 1-year follow-up of prescribing patterns of analgesics in primary health care.

https://arctichealth.org/en/permalink/ahliterature224422
Source
J Clin Pharm Ther. 1992 Feb;17(1):43-7
Publication Type
Article
Date
Feb-1992
Author
R. Ahonen
H. Enlund
V. Pakarinen
S. Riihimäki
Author Affiliation
Department of Social Pharmacy, University of Kuopio, Finland.
Source
J Clin Pharm Ther. 1992 Feb;17(1):43-7
Date
Feb-1992
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Analgesics
Drug Prescriptions - statistics & numerical data
Female
Finland
Humans
Male
Middle Aged
Primary Health Care - trends
Abstract
The prescription of analgesics and anti-inflammatory drugs (analgesics) was studied using computerized patient records from a Finnish health centre with a population base of some 27,000 inhabitants. A random sample of every fifth patient visiting the health centre in 1986 was chosen. This study sample consisted of 4,577 patients with 17,021 physician contacts and altogether 14,035 prescriptions during the 1-year follow-up: of these analgesics comprised 14.8%. The proportion of the study population who received at least one analgesic prescription was 23 +/- 1.2% (95% CI). The use of physician contacts as a base revealed 10.7 +/- 0.5% (95% CI) of the contacts with an analgesic prescription. The exposure to analgesics among males increased with age from 17% for those aged 15-34 years to 34% for those aged 75 years or more. Among women, exposure to analgesics increased from 17% (15-34 years) to 41% (75 years or more). Most of patients who received analgesic prescriptions were incidental users (one or two analgesic prescriptions per year). Only 4% of women and 3% of men were categorized as heavy users of analgesics (seven or more analgesic prescriptions per year). The proportion of heavy users increased with age and was highest in the oldest age-group (75 years or more). In order to make informed policy judgements about drug use in society, we need routine sales statistics and patient-specific drug-use data such as those presented in this paper.
PubMed ID
1548311 View in PubMed
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[3 physicians' prescriptions for narcotics criticized].

https://arctichealth.org/en/permalink/ahliterature109253
Source
Lakartidningen. 1970 Dec 16;67(51):6014-5
Publication Type
Article
Date
Dec-16-1970
Source
Lakartidningen. 1970 Dec 16;67(51):6014-5
Date
Dec-16-1970
Language
Swedish
Publication Type
Article
Keywords
Drug Prescriptions
Drug and Narcotic Control
Humans
Legislation, Drug
Narcotics
Substance-Related Disorders
Sweden
PubMed ID
5494327 View in PubMed
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A 5-year follow-up study of users of benzodiazepine: starting with diazepam versus oxazepam.

https://arctichealth.org/en/permalink/ahliterature282849
Source
Br J Gen Pract. 2016 Apr;66(645):e241-7
Publication Type
Article
Date
Apr-2016
Author
Ingunn Fride Tvete
Trine Bjørner
Tor Skomedal
Source
Br J Gen Pract. 2016 Apr;66(645):e241-7
Date
Apr-2016
Language
English
Publication Type
Article
Keywords
Adult
Anti-Anxiety Agents - therapeutic use
Anxiety - drug therapy - epidemiology
Depression - drug therapy - epidemiology
Diazepam - therapeutic use
Dose-Response Relationship, Drug
Drug Prescriptions - statistics & numerical data
Female
Follow-Up Studies
Humans
Male
Middle Aged
Norway - epidemiology
Oxazepam - therapeutic use
Prescription Drug Misuse - statistics & numerical data
Prevalence
Proportional Hazards Models
Risk factors
Substance-Related Disorders - epidemiology
Abstract
Drug dependency may develop during long-term benzodiazepine use, indicated, for example, by dose escalation. The first benzodiazepine chosen may affect the risk of dose escalation.
To detect possible differences in benzodiazepine use between new users of diazepam and oxazepam over time.
This 5-year prescription database study included 19 747 new benzodiazepine users, inhabitants of Norway, aged 30-60 years, with first redemption for diazepam or oxazepam.
Individuals starting on diazepam versus oxazepam were analysed by logistic regression with sex, age, other drug redemptions, prescriber's specialty, household income, education level, type of work, and vocational rehabilitation support as background variables. Time to reach a daily average intake of =1 defined daily doses (DDD) over a 3-month period was analysed using a Cox proportional hazard regression model.
New users of oxazepam had a higher risk for dose escalation compared with new users of diazepam. This was true even when accounting for differences in sociodemographic status and previous drug use (hazard ratio [HR] 1.33, 95% confidence interval = 1.17 to 1.51).
Most doctors prescribed, according to recommendations, oxazepam to individuals they may have regarded as prone to and at risk of dependency. However, these individuals were at higher risk for dose escalation even when accounting for differences in sociodemographic status and previous drug use. Differences between the two user groups could be explained by different preferences for starting drug, DDD for oxazepam being possibly too low, and some unaccounted differences in illness.
Notes
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Cites: Psychopharmacology (Berl). 1984;84(2):147-546438672
Cites: Eur J Clin Pharmacol. 2003 Oct;59(7):559-6312942224
Cites: Addiction. 2011 Dec;106(12):2086-10921714826
PubMed ID
26965028 View in PubMed
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[10,850 general practice consultations with elderly patients. From diagnosis-prescription-examination in Møre and Romsdal]

https://arctichealth.org/en/permalink/ahliterature72639
Source
Tidsskr Nor Laegeforen. 1997 Nov 10;117(27):3980-4
Publication Type
Article
Date
Nov-10-1997
Author
J. Straand
H. Sandvik
K. Rokstad
Author Affiliation
Seksjon for allmennmedisin, Universitetet i Bergen.
Source
Tidsskr Nor Laegeforen. 1997 Nov 10;117(27):3980-4
Date
Nov-10-1997
Language
Norwegian
Publication Type
Article
Keywords
Aged
Cardiovascular Diseases - diagnosis - drug therapy - epidemiology
English Abstract
Family Practice - statistics & numerical data
Female
Health Services for the Aged - statistics & numerical data
Humans
Male
Mental Disorders - diagnosis - drug therapy - epidemiology
Musculoskeletal Diseases - diagnosis - drug therapy - epidemiology
Norway - epidemiology
Prescriptions, Drug - statistics & numerical data
Referral and Consultation - statistics & numerical data
Respiratory Tract Diseases - diagnosis - drug therapy - epidemiology
Abstract
Over a period of two months in 1988 and 1989 general practitioners in the Norwegian county of Møre and Romsdal recorded all contacts with their patients. Participation was close to 100%. We report data from 10,850 surgery consultations with elderly patients (65 years and older). 60% of the consultations involved female patients, and 58% of the patients were 65-74 years old. New diagnoses were made in one-third of the cases; two-thirds were follow-ups. The most common groups of diagnoses were cardiovascular (28%), musculoskeletal (13%), psychiatric (8%) and respiratory diseases (8%). Almost 10% of all consultations were for hypertension. Drugs were prescribed in 45% of all cases. 27% of all prescriptions were for cardiovascular drugs, and 25% were for drugs for the nervous system. The 20 most common diagnoses made up more than half of the total number of diagnoses. Almost 70% of all prescriptions were for the ten most common therapeutic groups.
PubMed ID
9441427 View in PubMed
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A 10-year survey of inflammatory bowel diseases-drug therapy, costs and adverse reactions.

https://arctichealth.org/en/permalink/ahliterature71979
Source
Aliment Pharmacol Ther. 2001 Apr;15(4):475-81
Publication Type
Article
Date
Apr-2001
Author
P. Blomqvist
N. Feltelius
R. Löfberg
A. Ekbom
Author Affiliation
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden. Paul.Blomqvist@mep.ki.se
Source
Aliment Pharmacol Ther. 2001 Apr;15(4):475-81
Date
Apr-2001
Language
English
Publication Type
Article
Keywords
Adult
Adverse Drug Reaction Reporting Systems
Aged
Anti-Inflammatory Agents - adverse effects - economics - therapeutic use
Drug Costs - statistics & numerical data
Female
Health Surveys
Humans
Inflammatory Bowel Diseases - drug therapy - economics
Male
Middle Aged
Nutritional Support
Physician's Practice Patterns
Prescriptions, Drug - economics
Retrospective Studies
Steroids
Sweden
Abstract
BACKGROUND: Drug therapy for Crohn's disease and ulcerative colitis is based on anti-inflammatory and immunodulating drugs, nutritional support and surgical resection. Recently, new drugs have been introduced. AIM: To report drug prescriptions, costs and adverse reactions among inflammatory bowel disease patients in Sweden between 1988 and 1997. METHODS: Drug use was calculated from the national Diagnosis and therapy survey and drug costs from prescriptions and drug sales. Adverse drug reactions were obtained from the Medical Products Agency's National Pharmacovigilance system. RESULTS: The annual drug exposure for Crohn's disease was 0.55 million daily doses per million population, mainly supplementation and aminosalicylic acids. Mesalazine and olsalazine had 61% within this group. For ulcerative colitis patients, drug exposure was 0.61 million daily doses per million per year and aminosalicylic acids fell from 70% to 65%. For inflammatory bowel disease patients, corticosteroids and nutritional supplementation were common. The annual average cost for inflammatory bowel disease drugs was 7.0 million US dollars. Annually, 32 adverse drug reactions were reported, mainly haematological reactions such as agranulocytosis and pancytopenia (60%), followed by skin reactions. Only two deaths were reported. Aminosalicylic acids were the most commonly reported compounds. CONCLUSIONS: Drug use for inflammatory bowel disease in the pre-biologic agent era rested on aminosalicylic acid drugs and corticosteroids with stable levels, proportions and costs. The level of adverse drug reactions was low but haematological reactions support the monitoring of inflammatory bowel disease patients.
PubMed ID
11284775 View in PubMed
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25 years of pharmacoepidemiologic innovation: the Saskatchewan health administrative databases.

https://arctichealth.org/en/permalink/ahliterature138275
Source
J Popul Ther Clin Pharmacol. 2011;18(2):e245-9
Publication Type
Article
Date
2011

[1384 house calls to elderly patients in family practice. From diagnosis-prescriptions-examination in Møre and Romsdal]

https://arctichealth.org/en/permalink/ahliterature72638
Source
Tidsskr Nor Laegeforen. 1997 Nov 10;117(27):3984-7
Publication Type
Article
Date
Nov-10-1997
Author
J. Straand
H. Sandvik
Author Affiliation
Seksjon for allmennmedisin, Universitetet i Bergen.
Source
Tidsskr Nor Laegeforen. 1997 Nov 10;117(27):3984-7
Date
Nov-10-1997
Language
Norwegian
Publication Type
Article
Keywords
Aged
Cardiovascular Diseases - diagnosis - drug therapy - epidemiology
English Abstract
Family Practice - statistics & numerical data
Female
Health Services for the Aged - statistics & numerical data
Home Care Services - statistics & numerical data
House Calls - statistics & numerical data
Humans
Male
Mental Disorders - diagnosis - drug therapy - epidemiology
Musculoskeletal Diseases - diagnosis - drug therapy - epidemiology
Norway - epidemiology
Prescriptions, Drug - statistics & numerical data
Registries
Respiratory Tract Diseases - diagnosis - drug therapy - epidemiology
Abstract
Over a period of two months in 1988 and 1989 all general practitioners in the Norwegian county of Møre and Romsdal recorded all contacts with their patients. We report data from 1,384 house calls to elderly patients (65 years and older). House calls made up 11.3% of all face-to-face contacts between general practitioners and elderly patients. 59% of the visits were to female patients, and 60% were to patients 75 years and older. 23% of the house calls took place during weekends, and new diagnoses were made in 58% of the cases. The most common groups of diagnoses were cardiovascular (21%), respiratory (16%), and musculoskeletal diseases (13%). Drugs were prescribed for 42% of the house calls. 28% of all drugs prescribed were for the nervous system, while 26% were antibiotics for systemic use. Most house calls were made because of acute illnesses. Our results suggest that preventive home visits to the elderly are rarely, if ever, performed in general practice.
PubMed ID
9441428 View in PubMed
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Abramson: direct-to-consumer advertising will erode health care.

https://arctichealth.org/en/permalink/ahliterature157621
Source
CMAJ. 2008 Apr 22;178(9):1126-7
Publication Type
Article
Date
Apr-22-2008
Author
Ann Silversides
Source
CMAJ. 2008 Apr 22;178(9):1126-7
Date
Apr-22-2008
Language
English
Publication Type
Article
Keywords
Advertising as Topic
Canada
Drug Industry
Drug Prescriptions
Humans
Pharmaceutical Preparations
PubMed ID
18427081 View in PubMed
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Abuse of codeine separated from over-the-counter drugs containing acetylsalicylic acid and codeine.

https://arctichealth.org/en/permalink/ahliterature11779
Source
Int J Legal Med. 1993;105(5):279-81
Publication Type
Article
Date
1993
Author
S. Jensen
A C Hansen
Author Affiliation
Department of Forensic Pathology, Aarhus University, Risskov, Denmark.
Source
Int J Legal Med. 1993;105(5):279-81
Date
1993
Language
English
Publication Type
Article
Keywords
Aspirin - chemistry
Codeine - chemistry
Denmark
Drug Combinations
Drugs, Non-Prescription - chemistry
Humans
Substance Abuse Detection
Substance-Related Disorders - etiology
Abstract
In Denmark a new trend concerning the abuse of codeine has been observed. Danish drug abusers have discovered that codeine is easily separated from certain drugs containing acetylsalicylic acid and codeine. When separated the codeine can be used either orally or intravenously. Three different drugs combining acetylsalicylic acid and codeine are available in Denmark, but codeine is only easily separable from one of these. Applying the same procedure to the two other drugs produces unpredictable or unfavourable ratios of codeine to acetylsalicylic acid. In several countries, however, similar drugs combining acetylsalicylic acid and codeine are available. It is not possible from a list of constituents to predict how easily codeine can be separated from a particular drug. Therefore it is strongly recommended that relevant drugs are tested at local forensic laboratories. In case codeine is found to be very easily separated from a product appropriate action should be taken.
PubMed ID
8471545 View in PubMed
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[Abuse of doping preparations outside organized sports. A new challenge for health care].

https://arctichealth.org/en/permalink/ahliterature218841
Source
Tidsskr Nor Laegeforen. 1994 Feb 10;114(4):424-5
Publication Type
Article
Date
Feb-10-1994
Author
E. Haug
Author Affiliation
Hormonlaboratoriet Aker sykehus, Oslo.
Source
Tidsskr Nor Laegeforen. 1994 Feb 10;114(4):424-5
Date
Feb-10-1994
Language
Norwegian
Publication Type
Article
Keywords
Anabolic Agents - administration & dosage - adverse effects
Doping in Sports
Drug Prescriptions
Drug and Narcotic Control
Growth Hormone - administration & dosage - adverse effects
Humans
Norway
Physician's Role
Risk factors
PubMed ID
8009474 View in PubMed
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2470 records – page 1 of 247.