Skip header and navigation

Refine By

70 records – page 1 of 7.

A 2-yr national population study of pediatric ketoacidosis in Sweden: predisposing conditions and insulin pump use.

https://arctichealth.org/en/permalink/ahliterature92247
Source
Pediatr Diabetes. 2009 Feb;10(1):33-7
Publication Type
Article
Date
Feb-2009
Author
Hanas Ragnar
Lindgren Fredrik
Lindblad Bengt
Author Affiliation
Department of Pediatrics, Uddevalla Hospital, Uddevalla, Sweden. ragnar.hanas@vgregion.se
Source
Pediatr Diabetes. 2009 Feb;10(1):33-7
Date
Feb-2009
Language
English
Publication Type
Article
Keywords
Adolescent
Age of Onset
Child
Child, Preschool
Diabetic Ketoacidosis - drug therapy - epidemiology
Humans
Insulin Infusion Systems
Potassium - blood
Questionnaires
Sodium - blood
Sweden - epidemiology
Abstract
The aim was to investigate triggering factors and insulin pump usage (continuous subcutaneous insulin infusion, CSII) at diabetic ketoacidosis (DKA). Data from 1999 and 2000 were collected retrospectively from Sweden. In 1999 and 2000, 7.4 and 11.0%, respectively, of children with diabetes used CSII. One hundred and forty-two episodes of DKA (pH
PubMed ID
18761647 View in PubMed
Less detail

Acute acetylsalicylic acid poisoning: treatment with forced alkaline diuresis and diuretics.

https://arctichealth.org/en/permalink/ahliterature249506
Source
Eur J Clin Pharmacol. 1977 Oct 14;12(2):111-6
Publication Type
Article
Date
Oct-14-1977
Author
K J Berg
Source
Eur J Clin Pharmacol. 1977 Oct 14;12(2):111-6
Date
Oct-14-1977
Language
English
Publication Type
Article
Keywords
Acid-Base Equilibrium
Adolescent
Adult
Aspirin - poisoning
Barbiturates - poisoning
Blood Gas Analysis
Bumetanide - therapeutic use
Child, Preschool
Clinical Trials as Topic
Diuresis
Diuretics - therapeutic use
Female
Furosemide - therapeutic use
Gastric Lavage
Humans
Hydrogen-Ion Concentration
Male
Potassium - blood
Salicylates - blood
Abstract
101 patients were treated for acute acetylsalicylic acid (ASA) poisoning in the Nephrological Unit Trondheim between 1971-1975. On admission 33 of them had a serum salicylic acid (SA) concentration greater than 400 microgram/ml (mean 588 +/- 40 microgram/ml). This group was compared with a group of 11 children less than 5 years old with ASA poisoning and a mean serum SA on admission of 550 +/- 34 microgram/ml. Blood pH on admission was normal or elevated in all patients more than 12 years old (mean 7.43 +/- 0.01), whereas 7 of the 11 children suffered from metabolic acidosis. The results of forced alkaline diuresis produced by loop diuretics (bumetanide, furosemide) in ASA poisoned patients older than 12 years are reported. The mean T 1/2 of SA was 9.6 h in the treated group as compared to 18-22 h in untreated patients. There was no apparent difference between the diuretic effect of bumetanide and furosemide.
PubMed ID
21797 View in PubMed
Less detail

[ACUTE CORONARY SYNDROME WITHOUT ST SEGMENT ELEVATION: POSSIBILITIES FOR PREDICTING THE CLINICAL COURSE AT THE POST-HOSPITAL (6 AND 12 MONTHS) STAGE].

https://arctichealth.org/en/permalink/ahliterature275680
Source
Klin Med (Mosk). 2016;94(3):205-10
Publication Type
Article
Date
2016
Source
Klin Med (Mosk). 2016;94(3):205-10
Date
2016
Language
Russian
Publication Type
Article
Keywords
Acute Coronary Syndrome - complications - diagnosis - metabolism - mortality
Aged
Calcium - blood
Creatinine - blood
Electrocardiography
Female
Follow-Up Studies
Humans
Interleukin-10 - blood
Interleukin-6 - blood
Male
Melatonin - analogs & derivatives - urine
Middle Aged
Myocardial Infarction - epidemiology - etiology
Potassium - blood
Predictive value of tests
Prognosis
Risk assessment
Russia - epidemiology
Sodium - metabolism
Abstract
To measure blood IL-6, IL-10, creatinine levels, calcium, sodium and potassium in blood and saliva, melatonin in urine of patients with acute coronary syndrome without ST segment elevation for the prediction of the clinical course at the post-hospital stage.
The study included 93 patients with complicated (n = 46) and uncomplicated (n = 47) coronary syndrome without ST segment elevation. Blood IL-6, IL-1, creatinine levels, calcium, sodium and potassium in blood and saliva, melatoni n in urine were determined on days 1-3 after hospitalization. 6-hydroxymelatonin was measured by HPLC in urine collected between 23 p.m. and 8 a.m., melatonin i in urine collected between 8 a.m. and 23 p.m.
Complicated coronary syndrome was associated with increased levels of melatonin (night), blood IL-10 and Na, salivary, Na and Ca while the uncomplicated condition with increased blood melatonin (daytime), IL-6, creatinine, Ca, Na, K, and salivary K. 90 patients were followed up within 12 months after discharge. End-points developed in 36 (40%) of them. Logistic analysis yielded variables and 2 logistic regression equations The data on night melatonin +5 and +4 were included in ROC analysis. The night melatonin +5 values over 0.7453 were associated with increased risk of complications in the post-hospital period (6 months) and values of 0.7453 or lower with the enhanced probability of uncomplicated clinical course. Prognostic sensitivity was estimated at 90%, specificity at -54.39%. The night melatonin +4 values over 0.2903 were associated with increased risk of complications in the post-hospital period (12 months) and values of 0.2903 or lower with the enhanced probability of uncomplicated clinical course. Prognostic sensitivity was estimated at 77.8%, specificity at -59.26%.
The night melatonin +5 and +4 models can be used to predict the clinical course of acute coronary syndrome during 6 and 12 months of the post-hospitalization period.
PubMed ID
27522726 View in PubMed
Less detail

Ambulatory cardiac arrhythmias in relation to mild hypokalaemia and prognosis in community dwelling middle-aged and elderly subjects.

https://arctichealth.org/en/permalink/ahliterature281049
Source
Europace. 2016 Apr;18(4):585-91
Publication Type
Article
Date
Apr-2016
Author
Nick Mattsson
Golnaz Sadjadieh
Preman Kumarathurai
Olav Wendelboe Nielsen
Lars Køber
Ahmad Sajadieh
Source
Europace. 2016 Apr;18(4):585-91
Date
Apr-2016
Language
English
Publication Type
Article
Keywords
Age Factors
Aged
Atrial Premature Complexes - etiology - mortality - physiopathology
Biomarkers - blood
Denmark
Disease-Free Survival
Diuretics - therapeutic use
Electrocardiography, Ambulatory
Female
Humans
Hypokalemia - blood - complications - diagnosis - drug therapy - mortality
Independent living
Kaplan-Meier Estimate
Linear Models
Logistic Models
Male
Middle Aged
Multivariate Analysis
Potassium - blood
Predictive value of tests
Proportional Hazards Models
Risk factors
Severity of Illness Index
Tachycardia, Supraventricular - etiology - mortality - physiopathology
Time Factors
Ventricular Premature Complexes - diagnosis - etiology - mortality - physiopathology
Abstract
Severe hypokalaemia can aggravate arrhythmia tendency and prognosis, but less is known about risk of mild hypokalaemia, which is a frequent finding. We examined the associations between mild hypokalaemia and ambulatory cardiac arrhythmias and their prognosis.
Subjects from the cohort of the 'Copenhagen Holter Study' (n = 671), with no history of manifest cardiovascular (CV) disease or stroke, were studied. All had laboratory tests and 48-h ambulatory electrocardiogram (ECG) recording. The median follow-up was 6.3 years. p-Potassium was inversely associated with frequency of premature ventricular complexes (PVCs) especially in combination with diuretic treatment (r = -0.22, P = 0.015). Hypokalaemia was not associated with supraventricular arrhythmias. Subjects at lowest quintile of p-potassium (mean 3.42, range 2.7-3.6 mmol/L) were defined as hypokalaemic. Cardiovascular mortality was higher in the hypokalaemic group (hazard ratio and 95% confidence intervals: 2.62 (1.11-6.18) after relevant adjustments). Hypokalaemia in combination with excessive PVC worsened the prognosis synergistically; event rates: 83 per 1000 patient-year in subjects with both abnormalities, 10 and 15 per 1000 patient-year in those with one abnormality, and 3 per 1000 patient-year in subjects with no abnormality. One variable combining hypokalaemia with excessive supraventricular arrhythmias gave similar results in univariate analysis, but not after multivariate adjustments.
In middle-aged and elderly subjects with no manifest heart disease, mild hypokalaemia is associated with increased rate of ventricular but not supraventricular arrhythmias. Hypokalaemia interacts synergistically with increased ventricular ectopy to increase the risk of adverse events.
PubMed ID
26293625 View in PubMed
Less detail

Arterial pressure, left ventricular mass, and aldosterone in essential hypertension.

https://arctichealth.org/en/permalink/ahliterature195409
Source
Hypertension. 2001 Mar;37(3):845-50
Publication Type
Article
Date
Mar-2001
Author
A H El-Gharbawy
V S Nadig
J M Kotchen
C E Grim
K B Sagar
M. Kaldunski
P. Hamet
Z. Pausova
D. Gaudet
F. Gossard
T A Kotchen
Author Affiliation
Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Source
Hypertension. 2001 Mar;37(3):845-50
Date
Mar-2001
Language
English
Publication Type
Article
Keywords
Adult
African Continental Ancestry Group
Aldosterone - blood
Blood pressure
Body mass index
Canada
Circadian Rhythm
Electrocardiography
European Continental Ancestry Group
Female
France - ethnology
Humans
Hypertension - blood - physiopathology
Hypertrophy, Left Ventricular - physiopathology
Male
Middle Aged
Obesity - blood - physiopathology
Potassium - blood
Renin - blood
United States
Abstract
The purpose of the present study was to evaluate the relationship of aldosterone to blood pressure and left ventricular size in black American (n=109) and white French Canadian (n=73) patients with essential hypertension. Measurements were obtained with patients off antihypertensive medications and included 24-hour blood pressure monitoring, plasma renin activity and aldosterone, and an echocardiogram. Compared with the French Canadians, the black Americans had higher body mass indexes, higher systolic blood pressures, attenuated nighttime reduction of blood pressure, and lower serum potassium concentrations (P:
PubMed ID
11244006 View in PubMed
Less detail

Atrial Na,K-ATPase increase and potassium dysregulation accentuate the risk of postoperative atrial fibrillation.

https://arctichealth.org/en/permalink/ahliterature151950
Source
Cardiology. 2009;114(1):1-7
Publication Type
Article
Date
2009
Author
Cao Thach Tran
Thomas Andersen Schmidt
John Brochorst Christensen
Keld Kjeldsen
Author Affiliation
Laboratory for Molecular Cardiology, Medical Department B, The Heart Centre, Rigshospitalet, Juliane Maries Vej 20, Copenhagen DK-2100, Denmark. tran@dadlnet.dk
Source
Cardiology. 2009;114(1):1-7
Date
2009
Language
English
Publication Type
Article
Keywords
Aged
Atrial Fibrillation - enzymology - etiology - physiopathology
Denmark
Female
Heart Atria - enzymology
Homeostasis
Humans
Logistic Models
Male
Middle Aged
Myocardium - pathology
Ouabain - diagnostic use
Postoperative Complications - blood - enzymology - physiopathology
Potassium - blood
Sodium-Potassium-Exchanging ATPase - metabolism
Thoracic Surgery
Abstract
Postoperative atrial fibrillation is a common complication to cardiac surgery. Na,K-ATPase is of major importance for the resting membrane potential and action potential. The purpose of the present study was to evaluate the importance of Na,K-ATPase concentrations in human atrial biopsies and plasma potassium concentrations for the development of atrial fibrillation.
Atrial myocardial biopsies were obtained from 67 patients undergoing open chest cardiac surgery. Na,K-ATPase was quantified using vanadate-facilitated 3H-ouabain binding. Plasma potassium concentration was measured with ion-selective electrode.
In patients with preoperative sinus rhythm, 3H-ouabain-binding site concentration was 16% higher in patients developing postoperative atrial fibrillation compared to patients maintaining sinus rhythm [302 +/- 15 pmol/g wet weight (n = 20) vs. 261 +/- 11 mmol/g wet weight (n = 33), p = 0.03]. Also with multivariable analysis, 3H-ouabain-binding site concentration was significantly associated with the development of atrial fibrillation. High increase in plasma potassium concentration during the perioperative period and surgery was associated with postoperative atrial fibrillation.
The present study supports the increasing evidence of dysregulation of the potassium homeostasis as an important factor in the development of cardiac arrhythmias. High atrial Na,K-ATPase and sudden plasma potassium concentration increase may contribute to precipitate atrial fibrillation.
PubMed ID
19299895 View in PubMed
Less detail

The basis for common reference intervals for serum potassium.

https://arctichealth.org/en/permalink/ahliterature73421
Source
Ups J Med Sci. 1993;98(3):387-93
Publication Type
Article
Date
1993
Author
M S Djurhuus
P H Petersen
A. Rohold
S. Vadstrup
A. Uldall
Author Affiliation
Department of Clinical Chemistry, Odense University Hospital, Denmark.
Source
Ups J Med Sci. 1993;98(3):387-93
Date
1993
Language
English
Publication Type
Article
Keywords
Chemistry, Clinical - standards
Female
Humans
Male
Middle Aged
Models, Theoretical
Potassium - blood
Quality Assurance, Health Care
Quality Control
Reference Standards
Abstract
In order to investigate the relevance of the currently used lower reference limit for S-Potassium in Danish hospital laboratories, analytical bias in the measurement of S-Potassium was compared with the lower reference limit in each of 52 Danish hospital laboratories. The acceptable bias range was estimated according to Gowans et al on the basis of the result of two different reference sample groups. The estimated acceptable 0.95 bias range was 0.24 mmol/L, so the observed bias range of 0.23 mmol/L was within this limit. As all preanalytical errors tend to increase the measured S-Potassium, all acceptable bias should be in the direction of decreasing the measured value. It can be concluded that analytical performance allows for more uniform (even common) reference interval(s) in all Danish and perhaps Nordic hospital laboratories, provided that preanalytical errors can be controlled.
PubMed ID
7974870 View in PubMed
Less detail

Canadian home parenteral nutrition (HPN) registry: validation and patient outcomes.

https://arctichealth.org/en/permalink/ahliterature127079
Source
JPEN J Parenter Enteral Nutr. 2012 Jul;36(4):407-14
Publication Type
Article
Date
Jul-2012
Author
G. Fernandes
B. Kaila
K N Jeejeebhoy
L. Gramlich
D. Armstrong
J P Allard
Author Affiliation
University Health Network, Toronto General Hospital, Toronto, Ontario, Canada.
Source
JPEN J Parenter Enteral Nutr. 2012 Jul;36(4):407-14
Date
Jul-2012
Language
English
Publication Type
Article
Keywords
Bilirubin - blood
Canada
Female
Follow-Up Studies
Hospitalization
Humans
Liver Diseases - etiology - physiopathology
Male
Nutrition Assessment
Parenteral Nutrition, Home - adverse effects - methods
Potassium - blood
Quality of Life
Registries
Treatment Outcome
Abstract
In Canada, there are an estimated 400 home parenteral nutrition (HPN) patients. In 2006, a registry was created to gather patient outcome information. The aim of this study was to validate the registry and report on HPN patient outcomes.
Several demographic, clinical parameters were collected. For the validation, paired t test and intraclass correlation coefficient (ICC) were used to assess agreement between repeat entries. For the outcome report, paired t test was used to assess changes, and survival analysis was performed using the Kaplan-Meier method. Results are expressed as mean ± SEM.
On validation, there was high correlation/agreement (P
PubMed ID
22326909 View in PubMed
Less detail

70 records – page 1 of 7.