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34 records – page 1 of 4.

[Characteristics of the dynamics of herd immunity to the poliovirus and of the quality of the vaccination carried out against poliomyelitis]

https://arctichealth.org/en/permalink/ahliterature40172
Source
Zh Mikrobiol Epidemiol Immunobiol. 1983 Mar;(3):75-8
Publication Type
Article
Date
Mar-1983
Author
L V Vlasova
Iu I Vaserin
G P Stepanova
S F Zakirova
N Ia Venediktova
Source
Zh Mikrobiol Epidemiol Immunobiol. 1983 Mar;(3):75-8
Date
Mar-1983
Language
Russian
Publication Type
Article
Keywords
Antibodies, Viral - analysis
Antibody formation
Child, Preschool
English Abstract
Humans
Infant
Neutralization Tests
Poliomyelitis - immunology - prevention & control
Poliovirus Vaccine, Inactivated - administration & dosage
Polioviruses - immunology
Quality Control
Siberia
Urban Population
Abstract
The aim of this work was to study the state of immunity in children immunized with liquid poliomyelitis vaccine. During 1976-1981 the intensity of immunity to poliomyelitis in 653 children aged 1-3 years was studied. The study showed that at the period when liquid poliomyelitis vaccine was used the share immune to polioviruses, types 1 and 2, constituted 89.4% and 98.0%, respectively, as compared with 67.0% and 68.0% at the period when sugar-coated live dried poliomyelitis vaccine was administered. Changes in such epidemiological characteristics, as the percentage of persons with antibodies to poliovirus, were particularly essential in the age group of 1-2 years. In 1979 persons with antibodies to type 1 poliovirus constituted 94.0% as compared with 44.0% in 1976, while the percentage of persons found to be seronegative in respect of antibodies to polioviruses, types 1, 2 and 3, decreased 5-7 times. The quality of immunization carried out at the period, when liquid poliomyelitis vaccine was used, was shown to influence the size of the immune share, while having no effect on the geometric mean of the titer of antibodies to polioviruses.
PubMed ID
6303022 View in PubMed
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Characterization of a recombinant type 3/type 2 poliovirus isolated from a healthy vaccinee and containing a chimeric capsid protein VP1.

https://arctichealth.org/en/permalink/ahliterature31091
Source
J Gen Virol. 2003 Mar;84(Pt 3):573-80
Publication Type
Article
Date
Mar-2003
Author
Soile Blomqvist
Anne-Lise Bruu
Mirja Stenvik
Tapani Hovi
Author Affiliation
Department of Microbiology, Enterovirus Laboratory, National Public Health Institute (KTL), Mannerheimintie 166, 00300 Helsinki, Finland. soile.blomqvist@ktl.fi
Source
J Gen Virol. 2003 Mar;84(Pt 3):573-80
Date
Mar-2003
Language
English
Publication Type
Article
Keywords
Amino Acid Substitution
Animals
Antibodies, Viral - blood
Antigens, Viral - analysis - genetics
Binding Sites
Capsid Proteins - analysis - chemistry - genetics
Carrier State - blood - virology
Child, Preschool
Comparative Study
DNA-Directed RNA Polymerases - genetics
Feces - virology
Female
Genome, Viral
Humans
Male
Mice
Molecular Sequence Data
Norway
Poliomyelitis - immunology
Poliovirus - genetics - immunology - isolation & purification
Poliovirus Vaccine, Inactivated - immunology
Poliovirus Vaccine, Oral - genetics - immunology
Recombination, Genetic
Research Support, Non-U.S. Gov't
Vaccination
Viral Nonstructural Proteins - genetics - metabolism
Abstract
A Sabin 3/Sabin 2/Sabin 3 (S3/2/3) intertypic recombinant poliovirus was isolated from a faecal specimen from a 2-year-old healthy boy approximately 12 weeks after administration of oral poliovirus vaccine. The first recombination junction was in the genomic region encoding the VP1 capsid protein between nucleotide positions 3274 and 3285 (numbering according to Sabin 3) and the second was in the RNA polymerase region (nucleotide positions 6824 and 6825). The recombination had introduced six Sabin 2-derived amino acids into the Sabin 3 capsid environment in the carboxyl terminus of VP1. The complete genome of the recombinant virus differed from corresponding parental Sabin strains at 33 nucleotide positions, nine of them resulting in an amino acid substitution. Four substitutions were in the capsid proteins and five were in the region encoding the non-structural proteins. One amino acid was changed in the antigenic site 2B and two in site 3B. In addition, the whole antigenic site 3A was replaced by Sabin 2-specific amino acids, but the antigenic characteristics of the S3/2/3 did not show type 2-specific features. Neutralizing antibody titres in sera from Finnish children immunized with the inactivated poliovirus vaccine were not lower against the recombinant virus than against Sabin 3. Our results suggest that the chimeric virus was most likely generated by recombination events in the vaccinee, rather than representing progeny of circulating vaccine-derived virus.
PubMed ID
12604808 View in PubMed
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Discussion on papers on virus diseases

https://arctichealth.org/en/permalink/ahliterature2068
Source
Papers presented at the Symposium on Circumpolar Health Related Problems, Fairbanks, Alaska, July 23-28, 1967. Archives of Environmental Health. 1968 Oct; 17(4):555-557.
Publication Type
Article
Date
Oct-1968
  1 document  
Author
Reinhard, K.R
Author Affiliation
U.S. Indian Health Service
Source
Papers presented at the Symposium on Circumpolar Health Related Problems, Fairbanks, Alaska, July 23-28, 1967. Archives of Environmental Health. 1968 Oct; 17(4):555-557.
Date
Oct-1968
Language
English
Geographic Location
U.S.
Publication Type
Article
Digital File Format
Text - PDF
Physical Holding
Alaska Medical Library
Keywords
Adolescent
Adult
Alaska
Arctic Regions
Child
Cold Climate
Disease Outbreaks
Enterovirus
Epidemics
Humans
Neutralization Tests
Poliomyelitis - immunology
Poliovirus
Virus Diseases - epidemiology
Notes
From: Fortuine, Robert et al. 1993. The Health of the Inuit of North America: A Bibliography from the Earliest Times through 1990. University of Alaska Anchorage. Citation number 2006.
Documents

67-19-Discussions On Papers On Virus Diseases.pdf

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Elimination of poliomyelitis in Finland.

https://arctichealth.org/en/permalink/ahliterature240575
Source
Rev Infect Dis. 1984 May-Jun;6 Suppl 2:S457-60
Publication Type
Article
Author
K. Lapinleimu
Source
Rev Infect Dis. 1984 May-Jun;6 Suppl 2:S457-60
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Child
Child, Preschool
Finland
Humans
Immunity
Infant
Poliomyelitis - immunology - prevention & control
Poliovirus - isolation & purification
Poliovirus Vaccine, Inactivated - immunology
Vaccination
Vaccines, Attenuated - immunology
Abstract
In Finland paralytic poliomyelitis has disappeared after immunization programs carried out exclusively with inactivated poliovirus vaccine (IPV). A sharp decrease in the number of patients with poliomyelitis occurred after mass vaccination in 1960-1961, when 51% of the population had received the complete primary vaccination. Immunity is maintained by continuous vaccination of infants, whose vaccination rate is close to 98%. Intensive poliovirus surveillance in 1972-1974 revealed that dissemination of the virus has also virtually ceased. Serologic surveys indicate that greater than or equal to 90% of individuals older than 15 years of age possess antibodies to all viral types, but in the younger age groups the proportion with antibodies to types 1 and 3 is lower, a finding that is alarming, especially in the case of type 3. Revaccination of seronegative children and conscripts has induced rapid booster-like responses, indicating that fully vaccinated individuals, although without demonstrable antibodies, are protected against poliomyelitis. The new, improved IPV developed in Holland induces satisfactory antibody titers in all vaccinees, with two injections--or perhaps even one--leading to long-lasting immunity.
PubMed ID
6330841 View in PubMed
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Immune status to polioviruses in the child population of Romania between 2002-2005 as indicated by serological investigation in cases of acute flaccid paralysis (AFP) and facial paralysis (FP) and its use as a "national reference value" to evaluate the vaccination coverage in particular groups of healthy children.

https://arctichealth.org/en/permalink/ahliterature164117
Source
Rev Med Chir Soc Med Nat Iasi. 2006 Oct-Dec;110(4):1004-11
Publication Type
Article
Author
Anda Baicus
Mariana Combiescu
Ana Persu
Andrei Aubert-Combiescu
Author Affiliation
"I. Cantacuzino" National Institute of Research-Development for Microbiology and Immunology, Bucharest.
Source
Rev Med Chir Soc Med Nat Iasi. 2006 Oct-Dec;110(4):1004-11
Language
English
Publication Type
Article
Keywords
Adolescent
Child
Child, Preschool
Facial Paralysis - immunology
Female
Humans
Infant
Male
Muscle Hypotonia - immunology
Paralysis - immunology
Poliomyelitis - immunology
Poliovirus - immunology - isolation & purification
Poliovirus Vaccines - immunology
Population Surveillance - methods
Retrospective Studies
Abstract
Although the European region is polio free since 2002, the risk of importation from endemic regions remains present and a high level of population immunity must be maintained. In Romania during the period 2002-2005, 101 FP cases, 91 AFP cases and 29 healthy contacts (living in groups with low social and sanitary status, relatively low vaccination coverage named "at risk") could have been investigated serologically. Antibody prevalences for poliovirus types 1, 2, and 3 were: 97.2%, 98% and 81.2% for FP cases; 96.7%, 94.5% and 85.7% for AFP cases, and 85.7%, 82.1% and 53% for the group of healthy children at risk. The risk of the emergence and spread of cVDPVs remains present especially in "at risk" groups with the gaps in immunity, even in countries where indigenous wild polioviruses have already been eradicated.
PubMed ID
17438916 View in PubMed
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[Immunity of children in Kharkov against poliomyelitis]

https://arctichealth.org/en/permalink/ahliterature40273
Source
Zh Mikrobiol Epidemiol Immunobiol. 1983 Jan;(1):96-100
Publication Type
Article
Date
Jan-1983
Author
A I Nosatenko
L G Gruntovskaia
O G Golub
R B Ivanova
R K Nikitina
Source
Zh Mikrobiol Epidemiol Immunobiol. 1983 Jan;(1):96-100
Date
Jan-1983
Language
Russian
Publication Type
Article
Keywords
Adolescent
Antibodies, Viral - analysis
Child
Child, Preschool
Comparative Study
English Abstract
Humans
Immunity
Infant
Neutralization Tests
Poliomyelitis - immunology
Polioviruses - immunology
Ukraine
Urban Population
Abstract
The study of the state of herd immunity among the children of Kharkov, carried out in 1980-1981, has revealed different immunity levels in children of different age. The conclusion has been made that the constant control of the state of immunity to 3 types of poliovirus is necessary, especially in infants and in school children, as well as in those not attending children's institutions.
PubMed ID
6301175 View in PubMed
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[Immunity to diphtheria, tetanus and poliomyelitis in adolescents in the Province of Quebec, 1976-77].

https://arctichealth.org/en/permalink/ahliterature246671
Source
Union Med Can. 1979 Nov;108(11):1347-55
Publication Type
Article
Date
Nov-1979

[Immunity to poliomyelitis in adult population of Moscow region. Role of vaccine and wild polioviruses in its formation].

https://arctichealth.org/en/permalink/ahliterature158084
Source
Zh Mikrobiol Epidemiol Immunobiol. 2008 Jan-Feb;(1):41-6
Publication Type
Article
Author
V B Seibil'
L P Malyshkina
I K Lavrova
V F Efimova
G V Tamazian
L I Kaiumova
Source
Zh Mikrobiol Epidemiol Immunobiol. 2008 Jan-Feb;(1):41-6
Language
Russian
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Antibodies, Viral - blood - immunology
Antibody Specificity
Female
Humans
Male
Middle Aged
Poliomyelitis - immunology - prevention & control
Poliovirus - classification - immunology
Poliovirus Vaccines - classification - immunology
Rural Population
Russia
Tissue Donors
Abstract
Assessment of immunity to poliomyelitis in adults from 8 towns of Moscow region was conducted. Low levels of population immunity against some serotypes of poliovirus in several towns have been found. At the same time, these levels were high and very high in other towns. Measurement of levels of strain-specific antibodies to vaccine and wild polioviruses demonstrated wide circulation of wild polioviruses during past decades which had significant influence on formation of immunity. Substantial number of non-immune adults represents favorable conditions for circulation of vaccine polioviruses after cessation of vaccination, which, in its turn, could result in reestablishment of their neurovirulent properties and subsequent reemergence of poliomyelitis.
PubMed ID
18368751 View in PubMed
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34 records – page 1 of 4.