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286 records – page 1 of 29.

6-Hydroxycleroda-3,13-dien-15,16-olide protects neuronal cells from lipopolysaccharide-induced neurotoxicity through the inhibition of microglia-mediated inflammation.

https://arctichealth.org/en/permalink/ahliterature149311
Source
Planta Med. 2010 Feb;76(2):120-7
Publication Type
Article
Date
Feb-2010
Author
Yu-Tzu Shih
Ya-Yun Hsu
Fang-Rong Chang
Yang-Chang Wu
Yi-Ching Lo
Author Affiliation
Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung, Taiwan.
Source
Planta Med. 2010 Feb;76(2):120-7
Date
Feb-2010
Language
English
Publication Type
Article
Keywords
Animals
Anti-Inflammatory Agents - isolation & purification - pharmacology - therapeutic use
Cell Death - drug effects
Cell Line, Tumor
Diterpenes - isolation & purification - pharmacology - therapeutic use
Enzyme Inhibitors - pharmacology
Humans
Inflammation - prevention & control
Inflammation Mediators - metabolism
Lipopolysaccharides
Microglia - drug effects
Neurons - drug effects
Neurotoxicity Syndromes - prevention & control
Phytotherapy
Plant Extracts - chemistry - pharmacology - therapeutic use
Polyalthia - chemistry
Rats
Rats, Sprague-Dawley
Abstract
Polyalthia longifolia var. pendula is used as an antipyretic agent in indigenous systems of medicine. Microglia-mediated inflammation plays an important role in the pathway leading to neuronal cell death in a number of neurodegenerative diseases. The aim of this study was to investigate the effects of 6-hydroxycleroda-3,13-dien-15,16-olide (PL3) extracted from Polyalthia longifolia var. pendula on lipopolysaccharide(LPS)-induced inflammation in microglia-like HAPI cells and primary microglia cultures. In microglia-neuron co-cultures, LPS decreased the cell viability of neuroblastoma SH-SY5Y cells. LPS-induced cell death was attenuated by the NOS inhibitor, L-NAME, the COX-2 inhibitor, NS-398 or the NADPH oxidase inhibitor, DPI, respectively. In LPS-treated microglia cells, PL3 decreased the expression of iNOS, COX-2, gp91 (phox), and NF- kappaBp65, the degradation of I kappaB alpha, and the production of NO, PGE (2), iROS, and TNF- alpha. PL3 also enhanced the expression of HO-1, a cytoprotective and anti-inflammatory enzyme. Moreover, PL3 reduced LPS-activated microglia-induced cell death. The present results suggest that PL3 inhibits microglia-mediated inflammation and inflammation-related neuronal cell death. Therefore, PL3 has potential use for the treatment of inflammation-related neurodegenerative diseases.
PubMed ID
19653144 View in PubMed
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The acceptability of isoflavones as a treatment of menopausal symptoms: a European survey among postmenopausal women.

https://arctichealth.org/en/permalink/ahliterature70456
Source
Climacteric. 2005 Sep;8(3):230-42
Publication Type
Article
Date
Sep-2005
Author
C. Koebnick
M. Reimann
A. Carlsohn
S. Korzen-Bohr
S. Bügel
J. Hallund
L. Rossi
F. Branca
W. Hall
C. Williams
H-J F Zunft
K. O'Doherty Jensen
Author Affiliation
German Institute of Human Nutrition Potsdam-Rehbruecke, Department of Intervention Studies, Nuthethal, Germany.
Source
Climacteric. 2005 Sep;8(3):230-42
Date
Sep-2005
Language
English
Publication Type
Article
Keywords
Age Factors
Attitude to Health
Cross-Sectional Studies
Dietary Supplements
Europe
Female
Food Habits
Health Behavior
Humans
Isoflavones - therapeutic use
Life Style
Menopause
Middle Aged
Multivariate Analysis
Phytotherapy
Questionnaires
Research Support, Non-U.S. Gov't
Vitamins - therapeutic use
Abstract
OBJECTIVE: To investigate determinants of the acceptability of isoflavone products among postmenopausal women with regard to social and lifestyle factors, dietary habits, health concerns, food beliefs, menopausal symptoms and therapies, and to elucidate preferences for specific products. METHODS: A consumer survey was conducted among postmenopausal women in four European countries (Germany, Denmark, Italy and the UK), including a total of 465 respondents. RESULTS: The declared acceptability of isoflavones was highest in Germany (80%), followed by Italy (75%), the UK (59%) and Denmark (55%; p
PubMed ID
16390755 View in PubMed
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[A comprehensive approach to health preservation].

https://arctichealth.org/en/permalink/ahliterature203033
Source
Voen Med Zh. 1998 Dec;319(12):19-21
Publication Type
Article
Date
Dec-1998

Adaptogenic activity of a complex biomedication based on a northern renewable raw material.

https://arctichealth.org/en/permalink/ahliterature273839
Source
Wiad Lek. 2016;69(1 Pt 2):55-60
Publication Type
Article
Date
2016
Author
Vera V Anshakova
Albina V Stepanova
Dimitrii M Uvarov
Aigerim Sh Smagulova
Ksenia N Naumova
Petr P Vasiliev
Source
Wiad Lek. 2016;69(1 Pt 2):55-60
Date
2016
Language
English
Publication Type
Article
Keywords
Animals
Biological Availability
Exercise - physiology
Humans
Lichens - chemistry
Mice
Phytotherapy
Plant Extracts - pharmacokinetics
Rhodiola - chemistry
Russia
Swimming - physiology
Abstract
One of the methods of increasing bioavailability, and thus the therapeutic effectiveness of an active substances, along with decreasing its required dosage, is to generate highly effective "carrier: active substances" complexes where the active carrier both increases the bioavailability of the active substance at lower doses and has a detoxifying activity.
the aim of this work was study the properties of the carrier from the lichen thallome in both its solid pharmaceutical form and in combination with Rhodiola rosea.
the physiologically active plant extracts with enhanced adaptogenic pharmacological activity based on plant substances growing in Yakutia: Cladonia lichen thalli and Rhodiola rosea (Rhodiolarosea, fam.Crassulaceae) rhizomes, combined in a raw material dry-weight ratio of 10:1 We used a one step, solvent-free process, involving the use of mechanochemical ball mills relying on centrifugal acceleration of the 10-30 g grinding bodies.
A single-stage mechanochemical technology has been developed for obtaining highly effective solid-phase biocomplexes based on a"multipurpose active filler" - a polymer matrix of lichen ?-oligosaccharides. It has been shown that lichen, is a raw material from which can be sourced a filler with a strong adsorption activity for solid pharmaceutical forms.
It is considered statistically significant that a bicomponent plant mechanocomplex based on this filler - lichen ?-oligosaccharides and small amounts of Rhodiola rosea has a wide spectrum of adaptogenic action, increasing the resistance of laboratory animals to the effects of physical exercise and a variety of extreme factors.
PubMed ID
27164277 View in PubMed
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Source
J Sykepleien. 1993 Apr 20;81(7):5-11
Publication Type
Article
Date
Apr-20-1993
Author
S. Barstad
Source
J Sykepleien. 1993 Apr 20;81(7):5-11
Date
Apr-20-1993
Language
Norwegian
Publication Type
Article
Keywords
Acquired Immunodeficiency Syndrome - epidemiology - therapy
Child
Child Advocacy
Health Services, Indigenous
Humans
Norway
Phytotherapy
Research
Tanzania - epidemiology
Abstract
The World Health Organization has announced that within 3 years 10% of Tanzania's population of 26 million will be infected with the human immunodeficiency virus (HIV). But there is some faint hope in the research of Tanzanian traditional medicine. An almost 90-year-man, Waziri Mrisho, is credited with having treated AIDS patients successfully with herbs that strengthen the immune system. Margaret Nakamya was stricken by the symptoms of AIDs in March 1990. She was referred to Waziri and started using his herbs. 3 years later she weighs 49 kg compared to 40 kg before. The old man's son set up a little factory where he pulverizes herbs and sells them at the price he can command The 3 types of trees that the herbal medicine is taken from grow in the wild, but some have also been planted around the factory. Even if these herbs are effective, it will take years before the AIDS epidemic is over, when people have changed their lifestyles. The means of communication (TV, cinema, radio, telephone) are missing or inadequate. In the Kagera region, with 1.2 million inhabitants, 25% of pregnant women are HIV-infected and 65,000 children lost their parents to AIDS. There are 2000 children in Dar Es Salaam living in the streets. The Anglican St. Albans Church runs a center for street kids where they get meals 3 times a week. The nurse Ruth Nesje enlisted a Norwegian physician and homeopath in a research project involving 30 AIDS patients in Norway. The University in Bergen will do in vitro testing. One group of patients will receive both AZT and the herbs, another group will get only AZT, and the 3rd group will obtain only the herbs. The Norwegian Nursing Association, NORAD, and DANIDA also plan various projects in the Tanga region.
PubMed ID
8499187 View in PubMed
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An analysis of the subjective marijuana experience.

https://arctichealth.org/en/permalink/ahliterature251574
Source
Int J Addict. 1976;11(2):295-307
Publication Type
Article
Date
1976
Author
C. Adamec
R O Pihl
L. Leiter
Source
Int J Addict. 1976;11(2):295-307
Date
1976
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Age Factors
Alcohol Drinking
Amphetamines
California
Cannabis - pharmacology
Female
Heroin Dependence - epidemiology
Humans
Lysergic Acid Diethylamide
Male
Opium
Phytotherapy
Psychophysiology
Quebec
Questionnaires
Self Concept
Self Disclosure
Substance-Related Disorders
Abstract
Two hundred and thirty-six marijuana users who volunteered for a study in which they would use the drug were administered a Drug History and a Marihuana Effects Questionnaires. In addition to obtaining descriptive information of drug experiment volunteers and a factor analysis of the marijuana experience, the relationship between experience and effect variables were studied. The results of the above analysis suggest that the "typical" subject in marijuana experiments is not a "typical" user, that the marijuana experience is verbally definable, and that prior expectancies and histories of effect alter the experience.
PubMed ID
942628 View in PubMed
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An analysis of two indigenous reproductive health illnesses in a Nahua community in Veracruz, Mexico.

https://arctichealth.org/en/permalink/ahliterature121378
Source
J Ethnobiol Ethnomed. 2012;8:33
Publication Type
Article
Date
2012
Author
Vania Smith-Oka
Author Affiliation
Anthropology Department, 611 Flanner Hall, Notre Dame, IN 46556, USA. vsmithok@nd.edu
Source
J Ethnobiol Ethnomed. 2012;8:33
Date
2012
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Female
Humans
Interviews as Topic
Medicine, Traditional
Mexico
Middle Aged
Midwifery
Phytotherapy
Plant Preparations - therapeutic use
Plants, Medicinal
Pregnancy
Pregnancy Complications - drug therapy
Qualitative Research
Reproductive health
Uterine Prolapse - drug therapy - etiology
Wasting Syndrome - drug therapy - etiology
Women's health
Young Adult
Abstract
This article describes the local concepts indigenous Nahua women hold regarding their reproduction. Specifically it provides a description of two indigenous illnesses--isihuayo and necaxantle, it discusses their etiology, symptoms, and treatments, and it analyzes them within the local ethnomedical framework and sociopolitical context. A perception of female vulnerability is shown to be an underlying shaper of women's experiences of these illnesses.
This research took place in a small Nahua village in Mexico. Qualitative data on local perceptions of these illnesses were collected by a combination of participant observation and interviews. Ethnobotanical data was obtained through interviews, and medicinal plants were collected in home gardens, fields, stream banks, and forested areas. The total study population consisted of traditional birth attendants (N = 5), clinicians (N = 8), and laywomen (N = 48).
Results showed that 20% of the village women had suffered from one or both of these illnesses. The article includes a detailed description of the etiology, symptoms, and treatments of these illnesses. Data shows that they were caused by mechanical, physical, and social factors related to a woman's weakness and/or lack of support. Traditional birth attendants often treated women's illnesses. Five medicinal plants were salient in the treatment of these illnesses: Ocimum basilicum L., Mentzelia aspera L., Pedilanthus tithymaloides (L.) Poit., and Piper umbellatum L. were used for isihuayo, while Solanum wendlandii Hook f. was used for necaxantle.
The research on these two ethnomedical conditions is a useful case study to understanding how indigenous women experience reproductive health. Reproductive health is not simply about clinically-based medicine but is also about how biomedicine intersects with the local bodily concepts. By describing and analyzing indigenous women's ill health, one can focus upon the combination of causes--which extend beyond the physical body and into the larger structure that the women exist in.
Notes
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Cites: Br J Obstet Gynaecol. 1997 May;104(5):579-859166201
Cites: Soc Sci Med. 1998 Oct;47(8):1005-159723847
Cites: Soc Sci Med. 2005 Aug;61(4):785-9515950091
Cites: Med Anthropol Q. 2006 Dec;20(4):487-51517225656
Cites: BMJ. 2007 Oct 20;335(7624):819-2317947787
Cites: Soc Sci Med. 1993 Sep;37(5):671-88211281
Cites: Soc Sci Med. 2009 Jun;68(11):2069-7719362404
Cites: J Ethnobiol Ethnomed. 2010;6:920163730
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Cites: J Ethnobiol Ethnomed. 2011;7:1421569234
Cites: Soc Sci Med. 2004 Nov;59(10):2037-5115351471
Cites: J Ethnopharmacol. 2009 Jan 30;121(3):383-9919041707
PubMed ID
22913545 View in PubMed
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286 records – page 1 of 29.