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Aberrations in plasma phospholipid fatty acids in lung cancer patients.

https://arctichealth.org/en/permalink/ahliterature128904
Source
Lipids. 2012 Apr;47(4):363-9
Publication Type
Article
Date
Apr-2012
Author
Rachel A Murphy
Taylor F Bureyko
Marina Mourtzakis
Quincy S Chu
M Thomas Clandinin
Tony Reiman
Vera C Mazurak
Author Affiliation
Department of Agricultural, Food and Nutritional Science, University of Alberta, 4-126A Li Ka Shing Centre, Edmonton, AB T6G 2E1, Canada.
Source
Lipids. 2012 Apr;47(4):363-9
Date
Apr-2012
Language
English
Publication Type
Article
Keywords
Adenocarcinoma - drug therapy - metabolism - mortality
Aged
Antineoplastic Agents - administration & dosage - therapeutic use
Body mass index
Canada
Fatty Acids - analysis
Female
Humans
Lipid Metabolism - drug effects
Longitudinal Studies
Lung Neoplasms - drug therapy - metabolism - mortality
Male
Middle Aged
Neoplasm Staging
Phospholipids - analysis
Survival Rate
Weight Loss
Abstract
Abnormalities in lipid metabolism have been frequently observed in cancer and are associated with a poor prognosis. However, a detailed, longitudinal characterization of fatty acid status is lacking. This study aimed to assess plasma phospholipid fatty acids before chemotherapy, immediately after and 1 month following chemotherapy in a group of 50 patients newly diagnosed with lung cancer and explore factors which may contribute to aberrations in fatty acids. Their mean ± SD characteristics: age 64 ± 8.5 years, 75% advanced stage disease, body mass index 27.0 ± 5.4 kg/m², 6 month weight loss -4.6 ± 6.1%. Compared to patients with early stage disease, patients with advanced disease had abnormal fatty acid profiles including significantly lower (P
PubMed ID
22160451 View in PubMed
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Abyssivirga alkaniphila gen. nov., sp. nov., an alkane-degrading, anaerobic bacterium from a deep-sea hydrothermal vent system, and emended descriptions of Natranaerovirga pectinivora and Natranaerovirga hydrolytica.

https://arctichealth.org/en/permalink/ahliterature275915
Source
Int J Syst Evol Microbiol. 2016 Apr;66(4):1724-34
Publication Type
Article
Date
Apr-2016
Author
Anders Schouw
Tove Leiknes Eide
Runar Stokke
Rolf Birger Pedersen
Ida Helene Steen
Gunhild Bødtker
Source
Int J Syst Evol Microbiol. 2016 Apr;66(4):1724-34
Date
Apr-2016
Language
English
Publication Type
Article
Keywords
Alkanes - metabolism
Arctic Regions
Bacterial Typing Techniques
Base Composition
Biodegradation, Environmental
Clostridiales - classification - genetics - isolation & purification
DNA, Bacterial - genetics
Fatty Acids - chemistry
Glycolipids - chemistry
Hydrothermal Vents - microbiology
Molecular Sequence Data
Peptidoglycan - chemistry
Phospholipids - chemistry
Phylogeny
RNA, Ribosomal, 16S - genetics
Sequence Analysis, DNA
Abstract
A strictly anaerobic, mesophilic, syntrophic, alkane-degrading strain, L81T, was isolated from a biofilm sampled from a black smoker chimney at the Loki's Castle vent field. Cells were straight, rod-shaped, Gram-positive-staining and motile. Growth was observed at pH?6.2-9.5, 14-42?°C and 0.5-6?% (w/w) NaCl, with optima at pH?7.0-8.2, 37?°C and 3% (w/w) NaCl. Proteinaceous substrates, sugars, organic acids and hydrocarbons were utilized for growth. Thiosulfate was used as an external electron acceptor during growth on crude oil. Strain L81T was capable of syntrophic hydrocarbon degradation when co-cultured with a methanogenic archaeon, designated strain LG6, isolated from the same enrichment. Phylogenetic analysis based on the 16S rRNA gene sequence indicated that strain L81T is affiliated with the family Lachnospiraceae, and is most closely related to the type strains of Natranaerovirga pectinivora (92?% sequence similarity) and Natranaerovirga hydrolytica (90%). The major cellular fatty acids of strain L81T were C15?:?0, anteiso-C15?:?0 and C16?:?0, and the profile was distinct from those of the species of the genus Natranaerovirga. The polar lipids were phosphatidylglycerol, diphosphatidylglycerol, three unidentified phospholipids, four unidentified glycolipids and two unidentified phosphoglycolipids. The G+C content of genomic DNA was determined to be 31.7?mol%. Based on our phenotypic, phylogenetic and chemotaxonomic results, strain L81T is considered to represent a novel species of a new genus of the family Lachnospiraceae, for which we propose the name Abyssivirga alkaniphila gen. nov., sp. nov. The type strain of Abyssivirga alkaniphila is L81T (=DSM 29592T=JCM 30920T). We also provide emended descriptions of Natranaerovirga pectinivora and Natranaerovirga hydrolytica.
PubMed ID
26822139 View in PubMed
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[Activation of reparative processes by phospholipid preparation in the affected organs and tissues in neonathal enteropathology of calves]

https://arctichealth.org/en/permalink/ahliterature83018
Source
Ukr Biokhim Zh. 2004 Nov-Dec;76(6):111-6
Publication Type
Article
Author
Hryshchenko V A
Source
Ukr Biokhim Zh. 2004 Nov-Dec;76(6):111-6
Language
Ukrainian
Publication Type
Article
Keywords
Animals
Animals, Newborn
Cattle
Cattle Diseases - blood - drug therapy
Dyspepsia - blood - drug therapy - veterinary
Lipid Metabolism - drug effects
Phospholipids - chemistry - therapeutic use
Treatment Outcome
Abstract
The peculiarities of dynamics of quantitative changes of some classes of lipid and phospholipid spectra of blood plasma of calves recovered after dyspepsia were studied. Obtained reliable changes of the blood plasma lipidogrammas testify to development of dyslipidemia. It is characterized by hypercholesterolemia and hypertriacylglycerolemia of recovered 30 days old calves 3 weeks after diseases symptoms past. These changes give evidence concerning deficiency of phosphatides choline fraction - main structural components of cell membranes. It was established that changes of lipid and phospholipid spectra of blood plasma caused by enteropathology can be corrected by the inclusion of reparative therapy preparations to dyspepsia treatment plan in particular--experimental phospholipid containing a drug, which is prepared on the basis of milk phospholipids--its natural source for newborn calves.
PubMed ID
16350753 View in PubMed
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Alaska: an appraisal of the health and nutritional status of the Eskimo.

https://arctichealth.org/en/permalink/ahliterature1223
Source
Interdepartmental Committee on Nutrition for National Defense. [Washington, DC.] 165 pp.
Publication Type
Report
Date
August 1959
; Biochemical Findings, for National Guard and Villages, by Sex and Age Groups; Total Fatty Acids, Phospholipids and Cholesterol Alaska, Nutrition Survey, March 1958; Biochemical Findings, for National Guard and Villages, by Sex and Age Groups; Urinary Excretions Alaska, Nutrition Survey, March 1958
  1 document  
Source
Interdepartmental Committee on Nutrition for National Defense. [Washington, DC.] 165 pp.
Date
August 1959
Language
English
Geographic Location
U.S.
Publication Type
Report
File Size
6877041
Physical Holding
Alaska Medical Library
Keywords
Bethel
Akiak
Kasigluk
Napaskiak
Newtok
Hooper Bay
Kotzebue
Noatak
Point Hope
Shishmaref
Diet, traditional
Diet, western
Health status
Height
Weight
Blood pressure
Skinfold thickness
Vitamin A
Vitamin C
Dental caries
DMFT index
Periodontal disease
Beta-carotene
Fatty acids
Phospholipids
Cholesterol
Protein, serum
Vitamin B
Hemoglobin
Hematocrit
Riboflavin
Thiamin
Notes
From: Fortuine, Robert et al. 1993. The Health of the Inuit of North America: A Bibliography from the Earliest Times through 1990. University of Alaska Anchorage. Citation number 1156.
Cited in: Fortuine, Robert. 1968. The Health of the Eskimos: a bibliography 1857-1967. Dartmouth College Libraries. Citation number 275.
Documents

An-Appraisal-of-the-Health-and-Nutritional-Status-of-the-Eskimo-1959.pdf

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Alterations in lymphocyte function and relation to phospholipid composition after burn injury in humans.

https://arctichealth.org/en/permalink/ahliterature189117
Source
Crit Care Med. 2002 Aug;30(8):1753-61
Publication Type
Article
Date
Aug-2002
Author
Vera C Pratt
Edward E Tredget
M Thomas Clandinin
Catherine J Field
Author Affiliation
Department of Agricultural, Food, and Nutritional Science, University of Alberta, Ed-monton, Alberta, Canada.
Source
Crit Care Med. 2002 Aug;30(8):1753-61
Date
Aug-2002
Language
English
Publication Type
Article
Keywords
Adult
Aged
Antigens, CD - biosynthesis - immunology
Blood Cells - immunology
Burns - immunology - physiopathology - therapy
Canada
Cytokines - biosynthesis - immunology
Cytotoxicity, Immunologic - immunology
Enteral Nutrition
Female
Humans
Killer Cells, Natural - immunology
Lymphocytes - physiology
Male
Middle Aged
Phenotype
Phospholipids - chemistry - physiology
Prospective Studies
Time Factors
alpha-Linolenic Acid - metabolism - therapeutic use
Abstract
Lymphocyte functions are dependent on fatty acid composition of membranes, and impaired functions can predispose patients to infection after burn injury. The current study was designed to describe changes in lymphocyte-phospholipid composition and lymphocyte-related immune functions from early to late recovery time points after burn injury.
Prospective observational.
Firefighter's Burn Treatment Center, University of Alberta Hospital, Edmonton, Alberta, Canada.
Subjects (n = 10) with >10% total body surface burn area.
Blood was drawn from subjects at specific time points (0 days to >50 days) after burn injury. Fatty acid composition of the major phospholipid classes of isolated lymphocytes was determined by using gas liquid chromatography. Lymphocyte phenotypes and proliferation ([(3)H]-thymidine uptake and interleukin-2 and interferon-gamma production) in response to mitogens were determined. Lymphocyte phospholipid 20:4n-6 content was 30% to 60% lower early compared with late postburn time points (p
PubMed ID
12163788 View in PubMed
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Altered transfer of cholesteryl esters and phospholipids in plasma from alcohol abusers.

https://arctichealth.org/en/permalink/ahliterature10964
Source
Arterioscler Thromb Vasc Biol. 1997 Nov;17(11):2940-7
Publication Type
Article
Date
Nov-1997
Author
M J Liinamaa
M L Hannuksela
Y A Kesäniemi
M J Savolainen
Author Affiliation
Department of Internal Medicine and Biocenter Oulu, University of Oulu, Finland.
Source
Arterioscler Thromb Vasc Biol. 1997 Nov;17(11):2940-7
Date
Nov-1997
Language
English
Publication Type
Article
Keywords
Adult
Alcohol Drinking - blood
Alcoholism - blood
Apolipoproteins B - blood
Biological Transport
Carrier Proteins - blood
Cholesterol - blood
Cholesterol Esters - blood
Comparative Study
Glycoproteins
Humans
Lipoproteins, HDL - blood
Lipoproteins, VLDL - blood
Male
Membrane Proteins - blood
Middle Aged
Phospholipid Transfer Proteins
Phospholipids - blood
Research Support, Non-U.S. Gov't
Temperance
Triglycerides - blood
Abstract
The net mass transfer (NMT) of cholesteryl esters (CEs), triglycerides (TGs), and phospholipids (PLs) between lipoproteins was measured after incubation of fresh plasma for up to 2 hours from 18 male alcohol abusers and 17 male volunteer control subjects. In alcohol abusers the mean value of CE NMT was 3.7 nmol.mL-1.h-1 from apolipoprotein B-containing lipoproteins (apoB-containing lipoproteins) to HDL and in control subjects 8.7 nmol.mL-1.h-1 from HDL to apoB-containing lipoproteins. The NMT of PL was higher in alcohol abusers than in control subjects (35.0 vs 11.6 nmol.mL-1.h-1 from apoB-containing lipoproteins to HDL, respectively), and plasma PL transfer protein (TP) activity was 33% higher (P
PubMed ID
9409280 View in PubMed
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An epidemiological study of a Danish school population. I. Reference values for serum lipids based on a clinical and biochemical study of 284 girls and 268 boys.

https://arctichealth.org/en/permalink/ahliterature13196
Source
Acta Paediatr Scand. 1976 Nov;65(6):689-93
Publication Type
Article
Date
Nov-1976

Arachidonic acid level of non-esterified fatty acids and phospholipids in serum and heart muscle of patients with fatal myocardial infarction.

https://arctichealth.org/en/permalink/ahliterature55519
Source
Acta Med Scand. 1988;223(3):233-8
Publication Type
Article
Date
1988
Author
G. Skuladottir
E. Benediktsdottir
T. Hardarson
J. Hallgrimsson
G. Oddsson
N. Sigfusson
S. Gudbjarnason
Author Affiliation
Science Institute, University of Iceland, Reykjavik City Hospital.
Source
Acta Med Scand. 1988;223(3):233-8
Date
1988
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Arachidonic Acids - metabolism
Fatty Acids, Nonesterified - blood - metabolism
Humans
Middle Aged
Myocardial Infarction - blood - metabolism
Myocardium - metabolism
Phospholipids - blood - metabolism
Abstract
The relationship between non-esterified fatty acids (NEFA) in serum and heart muscle was examined in 15 patients who died of myocardial infarction (MI) and seven people who died suddenly in accidents. There was no correlation between NEFA levels of serum and non-infarcted cardiac muscle in patients with fatal MI. No significant difference was encountered in cardiac NEFA content between patients with fatal MI and people who died in accidents. The phospholipid (PL) content was significantly lower in patients with fatal MI than observed in people who died in accidents. The arachidonic acid (20:4 (n-6)) concentration of serum NEFA was significantly lower in patients with fatal MI compared to normal subjects. The cardiac NEFA and PL in patients with fatal MI contained significantly lower percentage levels of arachidonic acid compared to people who died in accidents. The results indicate that the death of the MI patients was not accompanied by elevated cardiac NEFA levels.
PubMed ID
3354349 View in PubMed
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Arcobacter lekithochrous sp. nov., isolated from a molluscan hatchery.

https://arctichealth.org/en/permalink/ahliterature285236
Source
Int J Syst Evol Microbiol. 2017 May;67(5):1327-1332
Publication Type
Article
Date
May-2017
Author
Ana L Diéguez
Sabela Balboa
Thorolf Magnesen
Jesús L Romalde
Source
Int J Syst Evol Microbiol. 2017 May;67(5):1327-1332
Date
May-2017
Language
English
Publication Type
Article
Keywords
Animals
Aquaculture
Arcobacter - classification - genetics - isolation & purification
Bacterial Typing Techniques
Base Composition
DNA, Bacterial - genetics
Fatty Acids - chemistry
Norway
Nucleic Acid Hybridization
Pecten - microbiology
Phospholipids - chemistry
Phylogeny
RNA, Ribosomal, 16S - genetics
Seawater - microbiology
Sequence Analysis, DNA
Vitamin K 2 - analogs & derivatives - chemistry
Abstract
Four bacterial strains, LFT 1.7T, LT2C 2.5, LT4C 2.8 and TM 4.6, were isolated from great scallop (Pecten maximus) larvae and tank seawater in a Norwegian hatchery and characterized by a polyphasic approach including determination of phenotypic, chemotaxonomic and genomic traits. All were Gram-stain-negative, motile rods, oxidase- and catalase-positive and required sea salts for growth. Major fatty acids present were summed feature 3 (C16?:?1?7c/C16?:?1?6c), summed feature 8 (C18?:?1?7c or C18?:?1?6c), C16?:?0, C14?:?0, summed feature 2 (C14?:?0 3-OH/iso-C16?:?1 I), C12?:?0 3-OH and C12?:?0. Strain LFT 1.7T contained menaquinone MK-6 as the sole respiratory quinone. Phylogenetic analysis based on 16S rRNA gene sequences indicated that all strains formed a distinct lineage within the genus Arcobacter with a low similarity to known species (94.77-95.32?%). The DNA G+C content was 28.7?mol%. Results of in silico DNA-DNA hybridization and average nucleotide identity confirmed that the isolates constitute a novel species of Arcobacter, for which the name Arcobacter lekithochrous sp. nov. is proposed. The type strain is LFT 1.7T (=CECT 8942T=DSM 100870T).
PubMed ID
28109200 View in PubMed
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Atherosclerosis and biochemical composition of coronary arteries in Finnish men. Comparison of two populations with different incidences of coronary heart disease.

https://arctichealth.org/en/permalink/ahliterature235241
Source
Atherosclerosis. 1987 May;65(1-2):109-15
Publication Type
Article
Date
May-1987
Author
S. Ylä-Herttuala
H. Sumuvuori
K. Karkola
M. Möttönen
T. Nikkari
Source
Atherosclerosis. 1987 May;65(1-2):109-15
Date
May-1987
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Arteries - analysis
Cholesterol - analysis
Coronary Artery Disease - metabolism
Coronary Disease - epidemiology
Coronary Vessels - analysis - pathology
Fatty Acids - analysis
Finland
Glycosaminoglycans - analysis
Humans
Male
Middle Aged
Phospholipids - analysis
Abstract
Men in Eastern Finland show a substantially higher rate of coronary heart disease (CHD) than men in the Western part of the country. To study possible differences in the biochemical composition and atherosclerotic involvement of coronary arteries between these two populations, we analyzed major lipid and non-lipid components of coronary arteries from 15- to 60-year-old Finnish men after accidental death. The material consisted of 59 age-matched pairs from East and West Finland, respectively, collected at successive autopsies during 1979-1983. The coronary arteries from East Finland contained significantly more esterified cholesterol and a higher percentage of oleate in cholesteryl esters. The findings were most conspicuous under the age of 40 years, and imply a higher degree of atherosclerosis together with an increased rate of intracellular cholesterol esterification in coronary arteries in Eastern as compared with Western Finland. The vessels from East Finland also tended to contain more free cholesterol and raised lesions, but the differences were not statistically significant. No major regional differences were seen in total phospholipids, phospholipid subfractions, DNA, calcium, collagen, total protein, or glycosaminoglycans.
PubMed ID
3606727 View in PubMed
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210 records – page 1 of 21.