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92 records – page 1 of 10.

[Analysis of some parameters of biological age and adaptation possibilities of workers of locomotive brigades].

https://arctichealth.org/en/permalink/ahliterature123355
Source
Adv Gerontol. 2012;25(1):57-62
Publication Type
Article
Date
2012
Author
V A Nazimko
E V Morgul'
O A Petrova
R G Sheikhova
L S Kozina
M A Savenko
D S Lysenko
Source
Adv Gerontol. 2012;25(1):57-62
Date
2012
Language
Russian
Publication Type
Article
Keywords
Adaptation, Physiological - drug effects
Aging, Premature - blood - etiology - genetics - prevention & control - psychology
Antioxidants - administration & dosage - metabolism - therapeutic use
Case-Control Studies
Chromosome Aberrations - drug effects - statistics & numerical data
Data Interpretation, Statistical
Erythrocytes - drug effects - metabolism
Humans
Lipid Peroxides - blood
Lymphocytes - drug effects - metabolism
Occupational Exposure - adverse effects
Oligopeptides - administration & dosage - therapeutic use
Phagocytosis - drug effects
Railroads
Russia
Abstract
The unfavorable factors of professional work of workers of locomotive brigades influence on speed of aging and adaptation possibilities of an organism. Analysis of the data obtained confirms the positive use of the peptide bioregulator Pinealon in maintenance the professional reliability of workers of locomotive brigades. Workers of locomotive brigades used preparation during two weeks (1 capsule containing 100 mkg of Pinealon 2 times a day). Pinealon application has improved parameters of biological age and indicators determining the effectiveness of adaptive reactions.
PubMed ID
22708445 View in PubMed
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Biological activity of Melaleuca alternifola (Tea Tree) oil component, terpinen-4-ol, in human myelocytic cell line HL-60.

https://arctichealth.org/en/permalink/ahliterature200599
Source
J Manipulative Physiol Ther. 1999 Sep;22(7):447-53
Publication Type
Article
Date
Sep-1999
Author
S S Budhiraja
M E Cullum
S S Sioutis
L. Evangelista
S T Habanova
Author Affiliation
Department of Research, National College of Chiropractic, Lombard, Ill, USA.
Source
J Manipulative Physiol Ther. 1999 Sep;22(7):447-53
Date
Sep-1999
Language
English
Publication Type
Article
Keywords
Anti-Infective Agents, Local - pharmacology
Cell Line
Dose-Response Relationship, Drug
Esterases - metabolism
Flow Cytometry
HL-60 Cells - drug effects
Humans
Leukocytes - drug effects - metabolism
Macrophage Activation - drug effects
Monocytes - drug effects
Phagocytosis - drug effects
Sensitivity and specificity
Tea Tree Oil - pharmacology
Terpenes - pharmacology
Abstract
Tea tree oil is an aboriginal Australian traditional medicine for bruises, insect bites, and skin infections. It was rediscovered in the 1920s as a topical antiseptic that is more effective than Phenol. Previous studies have demonstrated its antiseptic qualities, but its effects on human white blood cells have never been investigated.
To test the hypothesis that tea tree oil exerts its antiseptic action through white blood cell activation.
Crude oil and the purified "active" component were studied by using a model system that responds to bioactive components by induction of differentiation in white blood cells. Methods used included white blood cell oxidative burst assay (nitroblue tetrazolium [NBT] dye reduction); cell proliferation assay (tritiated thymidine incorporation); cell surface differentiation marker assay (flow cytometric quantitation of phycoerythrin-anti-CD 11b binding); cell viability assay (trypan blue exclusion); and cellular differentiation enzyme assay (white cell esterase staining).
Collectively, five assays that measure differentiation in white blood cells indicated monocytic differentiation after treatment with either crude oil or the purified active component. Both the crude oil and the purified active component, (+:-) terpinene-4-ol, caused a similar type and amount of differentiation. The culture of cells in medium containing serum caused more activation than in medium containing no serum.
The antiseptic activity of tea tree oil appears to be due, in part, to white blood cell activation.
PubMed ID
10519561 View in PubMed
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[Biorhythm of the tonsillar neutrophils in healthy children of the Tiumen region]

https://arctichealth.org/en/permalink/ahliterature41485
Source
Zh Ushn Nos Gorl Bolezn. 1979 Jan-Feb;(1):56-7
Publication Type
Article

[Blood cell phagocytic activity and free fatty acids content in rat brain in modeling of the brain blood supply disorders]

https://arctichealth.org/en/permalink/ahliterature88685
Source
Fiziol Zh. 2009;55(2):50-7
Publication Type
Article
Date
2009
Author
Iaremenko L M
Briuzhina T S
Hrabovyi O M
Source
Fiziol Zh. 2009;55(2):50-7
Date
2009
Language
Ukrainian
Publication Type
Article
Keywords
Animals
Arachidonic Acid - metabolism
Brain - blood supply - metabolism
Brain Ischemia - blood - metabolism
Cerebrovascular Circulation
Disease Models, Animal
Male
Oxidative Stress
Palmitic Acid - metabolism
Phagocytosis - physiology
Rats
Rats, Wistar
Abstract
Phagocytic activity of blood cells and free fatty acids content in rat brain were studied during experimental disturbances of blood supply. It is shown that disturbances of cerebral circulation in rats lead to a depression of a phagocytic part of immunity though during the expressed damage during the early periods its intensification is observed. During disturbances in brain circulation, the most significant changes are seeing in the contents of arachidonic and palmitic fatty acids. The level of changes in fatty acids contents and their dynamics depended on the degree of circulatory disturbances. Correlation communications between activity of phagocyte blood cells and changes in fatty acid content in rat brain during circulatory alterations point to the certain dependence on systemic oxidative stress.
PubMed ID
19526849 View in PubMed
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[Change in total immmunobiological reactivity of the organism in the process of acclimatization to the polar region].

https://arctichealth.org/en/permalink/ahliterature109328
Source
Voen Med Zh. 1970 Nov;11:44-6
Publication Type
Article
Date
Nov-1970
Author
M M Kantorovich
Source
Voen Med Zh. 1970 Nov;11:44-6
Date
Nov-1970
Language
Russian
Publication Type
Article
Keywords
Acclimatization
Arctic Regions
Cold Climate
Humans
Immunity
Military Medicine
Phagocytosis
USSR
PubMed ID
5508128 View in PubMed
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[Changes in the local nonspecific immune response to post-traumatic inflammation during treatment]

https://arctichealth.org/en/permalink/ahliterature46074
Source
Fiziol Zh. 2001;47(4):25-9
Publication Type
Article
Date
2001
Author
O O Tymofeiev
O V Horobets'
A H Portnychenko
K V Rozova
M M Seredenko
V I Portnichenko
J A Abbas
Author Affiliation
A.A. Bogomoletz Institute of Physiology, NAS of Ukraine, Shupyk Kiev Medical Academy of Post-graduation Education.
Source
Fiziol Zh. 2001;47(4):25-9
Date
2001
Language
Ukrainian
Publication Type
Article
Keywords
Adolescent
Adult
Aluminum - adverse effects - immunology
English Abstract
Fracture Fixation - adverse effects
Humans
Inflammation - immunology
Mandibular Fractures - immunology - therapy
Neutrophil Activation
Neutrophil Infiltration
Neutrophils - immunology
Phagocytosis
Splints - adverse effects
Steel - adverse effects
Treatment Outcome
Abstract
Clinical investigation have been done in adult patients with broken mandible during 3 weeks of conservative treatment with aluminum splints (1st group, n = 17) or steel splints (2nd group, n = 16) in comparison with health adults (control group, n = 18). The neutrophil emigration into alterative locus and their degranulation as well as phagocytic activity of peripheral blood neutrophils were tested. It was found that aluminum splint application caused the intensive inflammation and then the depression of local host defense reactions. Treatment with steel splints did not lead to neutrophil function depletion or to hyper-intensification of inflammatory reaction in patients. The increased values of neutrophil reactions were normalized in this group at the final period of the treatment. The examined trial ensures our accurate method in treatment of patients with broken mandible. The determination of local host defense state may be proposed as preferable simple express-method of evaluation of immune status, treatment efficiency and prognosis in these patients.
PubMed ID
11571919 View in PubMed
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[Characterization of immunity status in exposed residents of the Techa riverside villages 50 years after the onset of radiation exposure].

https://arctichealth.org/en/permalink/ahliterature155767
Source
Radiats Biol Radioecol. 2008 May-Jun;48(3):261-77
Publication Type
Article
Author
A V Akleev
E A Ovcharova
Source
Radiats Biol Radioecol. 2008 May-Jun;48(3):261-77
Language
Russian
Publication Type
Article
Keywords
Aged
Antigens, CD - immunology
Bone Marrow - immunology - radiation effects
Dose-Response Relationship, Radiation
Environmental Exposure
Female
Humans
Immune System - radiation effects
Immunoglobulin A - blood
Lymphocyte Count
Lymphocytes - immunology - radiation effects
Male
Middle Aged
Monocytes - immunology - radiation effects
Neutrophils - immunology - radiation effects
Phagocytosis - radiation effects
Radiation Injuries - blood - immunology
Rivers - chemistry
Rural Population
Siberia
Strontium Radioisotopes - toxicity
Time Factors
Water Pollutants, Radioactive - toxicity
Abstract
The goal of the study was to assess the state of immunity in exposed residents of the Techa riverside villages 50 years, or more, after the onset of radiation exposure. 127 chronically exposed persons and 55 unexposed persons were studied. The mean dose to red bone marrow (RBM) was 0.69 Sv in exposed subjects, the mean dose to soft tissue was 0.07 Sv, the mean dose rate amounted to 0.10 Sv/yr to RBM and 0.02 Sv/yr to soft tissues in 1950. The state of the basic links of the immunity system (cellular, humoral, mononuclear phagocyte system, cytokine spectrum, etc.) was assessed using conventional methods. Exposed persons manifested a significant reduction in the absolute counts of CD3+, CD4+, CD 11b+, CD16+ lymphocytes in the peripheral blood, as well as an increase in the relative counts of CD8+. The group comprised of the Techa riverside residents demonstrated an increased immunoregulatory index (exposed individuals: 1.47; controls: 1.71, p = 0.001). An increased production of Immunoglobulin A and increased proportions of CD25+ lymphocytes were revealed in exposed individuals. Changes in the phagocytic activity of neutrophils and monocytes were insignificant, and were primarily associated with changes in the proportions of pagocytes in the peripheral blood stream. The state of the immunity in chronically exposed individuals at late time after the begin of exposure is characterized by a number of specific features reflected primarily on the cellular immunity. No relationship between immunity changes and accumulated exposure dose and dose rate were noted over the period of maximum radiation exposures (1950).
PubMed ID
18689251 View in PubMed
Less detail

Clinical significance of neutrophil functional activity in HIV infection.

https://arctichealth.org/en/permalink/ahliterature219147
Source
Scand J Infect Dis. 1994;26(1):41-7
Publication Type
Article
Date
1994
Author
D. Gabrilovich
L. Ivanova
L. Serebrovskaya
G. Shepeleva
V. Pokrovsky
Author Affiliation
Laboratory of AIDS Epidemiology and Prevention, Central Institute of Epidemiology, Moscow, Russia.
Source
Scand J Infect Dis. 1994;26(1):41-7
Date
1994
Language
English
Publication Type
Article
Keywords
AIDS-Related Opportunistic Infections - immunology
Adolescent
Adult
Female
Granulocytes - physiology
HIV Infections - immunology
HIV-1
Health status
Homosexuality
Humans
Luminescent Measurements
Male
Neutrophils - enzymology - immunology - physiology
Phagocytosis - physiology
Russia
Sexual Behavior
Abstract
Functional activity of polymorphonuclear neutrophils (PMN) was tested in 63 HIV-1 infected patients. PMN chemiluminescence (CL) and intracellular enzyme activity were both depressed in patients at all stages of infection, though this depression was more pronounced in AIDS patients. We found no such depression when cells were incubated in the presence of autologous serum. PMN phagocytosis in the presence of serum was reduced in the early stage of HIV infection (LAS) but was in the normal range in AIDS patients. No differences in PMN functional activity between patients with LAS and those with dermatological disorders were found. The appearance of recurrent upper respiratory tract infection was associated with reduced PMN CL. The most pronounced changes in PMN activity were observed in patients with severe, recurrent bacterial pneumonia and Pneumocystis carinii pneumonia. A lower level of PMN activity was found in patients with infection progressing rapidly towards AIDS than in patients with a relatively stable course of infection. Thus, PMN CL may be regarded as a predictive factor for the progression of HIV infection.
PubMed ID
8191239 View in PubMed
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92 records – page 1 of 10.