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185 records – page 1 of 19.

A 10-month angiographic and 4-year clinical outcome of everolimus-eluting versus sirolimus-eluting coronary stents in patients with diabetes mellitus (the DiabeDES IV randomized angiography trial).

https://arctichealth.org/en/permalink/ahliterature275976
Source
Catheter Cardiovasc Interv. 2015 Dec 1;86(7):1161-7
Publication Type
Article
Date
Dec-1-2015
Author
Michael Maeng
Arvydas Baranauskas
Evald Høj Christiansen
Anne Kaltoft
Niels Ramsing Holm
Lars Romer Krusell
Jan Ravkilde
Hans-Henrik Tilsted
Per Thayssen
Lisette Okkels Jensen
Source
Catheter Cardiovasc Interv. 2015 Dec 1;86(7):1161-7
Date
Dec-1-2015
Language
English
Publication Type
Article
Keywords
Aged
Cardiovascular Agents - administration & dosage
Coronary Angiography
Coronary Artery Disease - mortality - radiography - therapy
Coronary Restenosis - mortality - radiography
Coronary Stenosis - mortality - radiography - therapy
Coronary Thrombosis - mortality - radiography
Denmark
Diabetic Angiopathies - mortality - radiography - therapy
Drug-Eluting Stents
Everolimus - administration & dosage
Female
Humans
Male
Middle Aged
Myocardial Infarction - mortality - radiography
Percutaneous Coronary Intervention - adverse effects - instrumentation - mortality
Predictive value of tests
Prospective Studies
Prosthesis Design
Risk factors
Sirolimus - administration & dosage
Time Factors
Treatment Outcome
Abstract
We aimed to compare angiographic and clinical outcomes after the implantation of everolimus-eluting (EES) and sirolimus-eluting (SES) stents in patients with diabetes.
There are limited data on long-term outcome after EES vs SES implantation in diabetic patients.
We randomized 213 patients with diabetes and coronary artery disease to EES (n?=?108) or SES (n?=?105) implantation. Angiographic follow-up was performed 10 months after the index procedure and all patients were followed clinically for 4 years. The primary endpoint was angiographic in-stent late luminal loss at 10-month follow-up. Secondary endpoints included angiographic restenosis rate, the need for target lesion revascularization (TLR) and major adverse cardiac events (MACE; defined as cardiac death, myocardial infarction, definite stent thrombosis, or TLR) at 4-year follow-up.
At 10-month angiographic follow-up, in-stent late lumen loss was 0.20?±?0.53 mm and 0.11?±?0.49 mm (P?=?0.28), and angiographic restenosis rate was 3.8% and 5.2% (P?=?0.72) in the EES and SES groups, respectively. At 4-year clinical follow-up, MACE had occurred in 22 (20.4%) patients in the EES group and 25 (23.8%) patients in SES group (HR 0.84, 95% CI 0.47-1.49; P?=?0.55), with TLR performed in 6 (5.6%) and 10 (9.5%) patients in the two groups (HR 0.57, 95% CI 0.21-1-58; P?=?0.28).
EES and SES had comparable 10-month angiographic and 4-year clinical outcomes in patients with diabetes mellitus and coronary artery disease.
PubMed ID
25640050 View in PubMed
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The 2011 outcome from the Swedish Health Care Registry on Heart Disease (SWEDEHEART).

https://arctichealth.org/en/permalink/ahliterature108055
Source
Scand Cardiovasc J. 2013 Jun;47 Suppl 62:1-10
Publication Type
Article
Date
Jun-2013
Author
Jan Harnek
Johan Nilsson
Orjan Friberg
Stefan James
Bo Lagerqvist
Kristina Hambraeus
Asa Cider
Lars Svennberg
Mona From Attebring
Claes Held
Per Johansson
Tomas Jernberg
Author Affiliation
Department of Coronary Heart Disease, Skåne University Hospital, Institution of Clinical Sciences, Lund University, Lund, Sweden. jan.harnek@skane.se
Source
Scand Cardiovasc J. 2013 Jun;47 Suppl 62:1-10
Date
Jun-2013
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Aged, 80 and over
Cardiac Surgical Procedures
Cardiology Service, Hospital - standards
Child
Child, Preschool
Coronary Angiography
Coronary Care Units - standards
Female
Heart Diseases - diagnosis - mortality - therapy
Humans
Infant
Infant, Newborn
Male
Medical Record Linkage
Middle Aged
Outcome and Process Assessment (Health Care) - standards
Percutaneous Coronary Intervention
Quality Improvement - standards
Quality of Health Care - standards
Registries
Secondary Prevention
Sweden - epidemiology
Time Factors
Treatment Outcome
Young Adult
Abstract
The Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART) collects data to support the improvement of care for heart disease.
SWEDEHEART collects on-line data from consecutive patients treated at any coronary care unit n = (74), followed for secondary prevention, undergoing any coronary angiography, percutaneous coronary intervention, percutaneous valve or cardiac surgery. The registry is governed by an independent steering committee, the software is developed by Uppsala Clinical Research Center and it is funded by The Swedish national health care provider independent of industry support. Approximately 80,000 patients per year enter the database which consists of more than 3 million patients.
Base-line, procedural, complications and discharge data consists of several hundred variables. The data quality is secured by monitoring. Outcomes are validated by linkage to other registries such as the National Cause of Death Register, the National Patient Registry, and the National Registry of Drug prescriptions. Thanks to the unique social security number provided to all citizens follow-up is complete. The 2011 outcomes with special emphasis on patients more than 80 years of age are presented.
SWEDEHEART is a unique complete national registry for heart disease.
PubMed ID
23941732 View in PubMed
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Acute coronary syndrome in octogenarians: association between percutaneous coronary intervention and long-term mortality.

https://arctichealth.org/en/permalink/ahliterature273526
Source
Clin Interv Aging. 2015;10:1547-53
Publication Type
Article
Date
2015
Author
Salim Bary Barywani
Shijun Li
Maria Lindh
Josefin Ekelund
Max Petzold
Per Albertsson
Lars H Lund
Michael Lx Fu
Source
Clin Interv Aging. 2015;10:1547-53
Date
2015
Language
English
Publication Type
Article
Keywords
Acute Coronary Syndrome - mortality - therapy
Aged, 80 and over
Cause of Death
Female
Humans
Kaplan-Meier Estimate
Male
Percutaneous Coronary Intervention
Propensity Score
Risk factors
Sweden - epidemiology
Abstract
Evidence of improved survival after use of percutaneous coronary intervention (PCI) in elderly patients with acute coronary syndrome (ACS) is limited. We assessed the association between PCI and long-term mortality in octogenarians with ACS.
We followed 353 consecutive patients aged =80 years hospitalized with ACS during 2006-2007. Among them, 182 were treated with PCI, whereas 171 were not. PCI-treated patients were younger and more often male, and had less stroke and dependency in activities of daily living, but there were no significant differences in occurrence of diabetes mellitus, chronic obstructive pulmonary disease, hypertension, and uncured malignancies between the two groups. The association between PCI and all-cause mortality was assessed in the overall cohort and a 1:1 matched cohort based on propensity score (PS). In overall cohort, 5-year all-cause mortality was 46.2% and 89.5% in the PCI and non-PCI groups, respectively. Cox regression analysis in overall cohort by adjustment for ten baseline variables showed statistically significant association between PCI and reduced long-term mortality (P
Notes
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PubMed ID
26451095 View in PubMed
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The acutely occluded left main coronary artery culprit in cardiogenic shock and initial percutaneous coronary intervention: a substudy of the Manitoba "no option" left main PCI registry.

https://arctichealth.org/en/permalink/ahliterature121376
Source
Can J Physiol Pharmacol. 2012 Sep;90(9):1325-31
Publication Type
Article
Date
Sep-2012
Author
Farrukh Hussain
Thang Nguyen
Nader Elmayergi
John Ducas
Kunal Minhas
Minh Vo
Malek Kass
Amir Ravandi
Gurpreet Parmar
Davinder S Jassal
James W Tam
Darren Freed
Alan H Menkis
Roger K Philipp
Author Affiliation
Department of Cardiology, Saint Boniface General Hospital, University of Manitoba, Winnipeg, Canada. fhussain@sbgh.mb.ca
Source
Can J Physiol Pharmacol. 2012 Sep;90(9):1325-31
Date
Sep-2012
Language
English
Publication Type
Article
Keywords
Acute Disease
Canada
Cohort Studies
Coronary Occlusion - complications - mortality - surgery
Coronary Thrombosis - complications - mortality - surgery
Female
Hospital Mortality
Hospitals, University - statistics & numerical data
Humans
Male
Middle Aged
Percutaneous Coronary Intervention - methods - mortality - statistics & numerical data
Registries
Retrospective Studies
Severity of Illness Index
Shock, Cardiogenic - etiology - mortality - surgery
Treatment Outcome
Abstract
We aim to describe the in-hospital outcomes of the first reported Canadian cohort of patients with cardiogenic shock and acute myocardial infarction (MI) due to acute and total occlusion of the left main coronary artery, treated with initial percutaneous coronary intervention (PCI). Acute left main thromboses with cardiogenic shock were identified (N = 8) from a retrospective consecutive cohort of high risk left main PCI (N = 56) performed at our institution from 2004-2009. The mean age was 62.3 ± 13.2 years, with 6 (75%) male patients. Successful PCI was performed in all patients, with thrombectomy utilized in 4 patients (50%), stenting in 7 patients (88%), and intra-aortic balloon pump augmentation in 7 patients (88%). Two patients (25%) required extracorporeal membrane oxygenation (ECMO) and 2 other patients required ventricular assist devices. Post-PCI coronary artery bypass grafting (CABG) was performed for 2 patients (25%). The mean SYNTAX score was 26.6 ± 10.5. The mean logistic EuroSCORE was 30.4 ± 12.6%. In-hospital mortality occurred in 3 patients (38%). Acute left main occlusion is a rare but devastating presentation of myocardial infarction, invariably with cardiogenic shock. Emergent PCI may be an effective method to acutely revascularize this subset of patients; however, aggressive post-PCI care including ECMO, CABG, and ventricular support may be required to improve patient survival.
PubMed ID
22913597 View in PubMed
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[Acute non ST-elevation coronary syndrome in real practice of hospitals in Russia. Comparative data from RECORD 2 and RECORD registries].

https://arctichealth.org/en/permalink/ahliterature119478
Source
Kardiologiia. 2012;52(10):9-16
Publication Type
Article
Date
2012
Author
A D Erlikh
N A Gratsianskii
Source
Kardiologiia. 2012;52(10):9-16
Date
2012
Language
Russian
Publication Type
Article
Keywords
Acute Coronary Syndrome - diagnosis - epidemiology - therapy
Adult
Aged
Aged, 80 and over
Anticoagulants - administration & dosage
Coronary Angiography
Electrocardiography
Female
Follow-Up Studies
Heparin, Low-Molecular-Weight - administration & dosage
Hospital Mortality - trends
Hospitals - statistics & numerical data
Humans
Incidence
Injections, Subcutaneous
Male
Middle Aged
Percutaneous Coronary Intervention
Platelet Aggregation Inhibitors - administration & dosage
Registries
Retrospective Studies
Russia - epidemiology
Survival Rate - trends
Ticlopidine - administration & dosage - analogs & derivatives
Treatment Outcome
Young Adult
Abstract
to compare data on pre- and in hospital treatment of non ST-elevation (NSTE) acute coronary syndromes (ACS) in Russian ACS registers RECORD (recruitment from 11.2007 to 02.2008) and RECORD-2 (from 04/2009 to 04.2011).
Four of 7 hospitals participating in RECORD-2 were invasive (57.1% vs. 55.6% in RECORD). In RECORD-2 10-30 consecutive patients with NSTEACS were included monthly in each center; recruitment in RECORD was described elsewhere.
Mean age of patients was similar in two registries. Portion of women was significantly higher in RECORD-2 (42.9% vs. 26.0% in RECORD; 140) gave results close to those in all patients except mortality which was statistically similar but numerically higher in RECORD-2 (9.3 vs. 7.9% in RECORD; p=0.68).
Comparison of data of 2 limited NSTEACS registers conducted with interval of about 2 years showed only modest shift towards fulfillment of contemporary recommendations which was not associated with increase in rates of PCI and improvement of outcomes especially in high risk patients.
PubMed ID
23098345 View in PubMed
Less detail
Source
Ugeskr Laeger. 2013 Sep 2;175(36):2053-4
Publication Type
Article
Date
Sep-2-2013
Source
Ugeskr Laeger. 2013 Mar 4;175(10):682
Publication Type
Article
Date
Mar-4-2013
Author
Steen Carstensen
Kardiologisk Afdeling
Roskilde Sygehus
Author Affiliation
sct@regionsjaelland.dk
Source
Ugeskr Laeger. 2013 Mar 4;175(10):682
Date
Mar-4-2013
Language
Danish
Publication Type
Article
Keywords
Denmark
Humans
Myocardial Infarction - therapy
Percutaneous Coronary Intervention
Time-to-Treatment
PubMed ID
23589915 View in PubMed
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Angiographic findings and survival in patients undergoing coronary angiography due to sudden cardiac arrest in western Sweden.

https://arctichealth.org/en/permalink/ahliterature269292
Source
Resuscitation. 2015 May;90:13-20
Publication Type
Article
Date
May-2015
Author
Björn Redfors
Truls Råmunddal
Oskar Angerås
Christian Dworeck
Inger Haraldsson
Dan Ioanes
P. Petursson
Berglind Libungan
Jacob Odenstedt
Jason Stewart
Lotta Robertsson
Magnus Wahlin
Per Albertsson
Johan Herlitz
Elmir Omerovic
Source
Resuscitation. 2015 May;90:13-20
Date
May-2015
Language
English
Publication Type
Article
Keywords
Acute Coronary Syndrome - mortality - radiography - therapy
Aged
Coronary Angiography
Coronary Artery Disease - mortality - radiography - therapy
Coronary Occlusion - mortality - radiography - therapy
Female
Heart Arrest - mortality
Humans
Logistic Models
Male
Percutaneous Coronary Intervention
Propensity Score
Proportional Hazards Models
Prospective Studies
Registries
Severity of Illness Index
Sweden - epidemiology
Abstract
Sudden cardiac arrest (SCA) accounts for more than half of all deaths from coronary heart disease. Time to return of spontaneous circulation is the most important determinant of outcome but successful resuscitation also requires percutaneous coronary intervention in selected patients. However, proper selection of patients is difficult. We describe data on angiographic finding and survival from a prospectively followed SCA patient cohort.
We merged the RIKS-HIA registry (Register of Information and Knowledge about Swedish Heart Intensive Care Admissions) and SCAAR (Swedish Coronary Angiography and Angioplasty Registry) for patients hospitalized in cardiac care units in Western Sweden between January 2005 and March 2013. We performed propensity score-adjusted logistic and Cox proportional-hazards regression analyses on complete-case data as well as on imputed data sets.
638 consecutive patients underwent coronary angiography due to SCA. Severity of coronary artery disease was similar among SCA patients and patients undergoing coronary angiography due to suspected coronary artery disease (n=37,142). An acute occlusion was reported in the majority of SCA patients and was present in 37% of patients who did not have ST-elevation on the post resuscitation ECG. 31% of SCA patients died within 30 days. Long-term risk of death among patients who survived the first 30 days was higher in patients with SCA compared to patients with acute coronary syndromes (P
PubMed ID
25698668 View in PubMed
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Antithrombotic therapy after coronary stenting in patients with nonvalvular atrial fibrillation.

https://arctichealth.org/en/permalink/ahliterature119558
Source
Can J Cardiol. 2013 Feb;29(2):213-8
Publication Type
Article
Date
Feb-2013
Author
Kay W Ho
Joan Ivanov
Xavier Freixa
Christopher B Overgaard
Mark D Osten
Douglas Ing
Eric Horlick
Karen Mackie
Peter H Seidelin
Vladimír D┼żavík
Author Affiliation
Interventional Cardiology Program, Division of Cardiology, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Source
Can J Cardiol. 2013 Feb;29(2):213-8
Date
Feb-2013
Language
English
Publication Type
Article
Keywords
Aged
Atrial Fibrillation - complications
Female
Fibrinolytic Agents - adverse effects - therapeutic use
Follow-Up Studies
Humans
Incidence
Male
Myocardial Ischemia - complications - surgery
Ontario - epidemiology
Percutaneous Coronary Intervention - adverse effects - methods
Postoperative Hemorrhage - chemically induced - epidemiology
Prognosis
Retrospective Studies
Risk factors
Stents
Stroke - epidemiology - etiology - prevention & control
Abstract
The safety and efficacy of triple therapy (TT; warfarin with dual antiplatelet therapy [DAPT]) in post-percutaneous coronary intervention (PCI) patients with atrial fibrillation (AF) are unclear. We aimed to determine whether TT is associated with a decreased stroke rate and an acceptable bleeding rate in this population.
This was a single-centre, retrospective study. Primary composite outcome was death, ischemic stroke, or transient ischemic attack. Secondary outcomes included components of primary outcome, bleeding, and blood transfusion rates.
Of 602 post-PCI patients with AF between 2000 and 2009, 382 received TT, 220 DAPT. Mean follow-up post PCI was 5.9 ± 5.0 months. The TT group had a higher CHADS(2) score (2.6 vs 2.1, P 2), and -3.2 (overall) per 100 patient-years.
Although we found no association with TT usage and a reduction in cerebrovascular ischemic or major bleeding events in post-PCI patients with AF regardless of CHADS(2) score vs DAPT, the study was likely underpowered to demonstrate a clinically relevant reduction. TT was associated with a 5-fold increase in gastrointestinal bleeding vs DAPT. Net clinical benefit calculations suggest benefits of TT in patients with CHADS(2) > 2. Stratification with CHADS(2) might be useful to determine the optimal antithrombotic therapy post PCI.
Notes
Comment In: Can J Cardiol. 2013 Feb;29(2):136-823089529
PubMed ID
23089528 View in PubMed
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185 records – page 1 of 19.