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Canadian home parenteral nutrition (HPN) registry: validation and patient outcomes.

https://arctichealth.org/en/permalink/ahliterature127079
Source
JPEN J Parenter Enteral Nutr. 2012 Jul;36(4):407-14
Publication Type
Article
Date
Jul-2012
Author
G. Fernandes
B. Kaila
K N Jeejeebhoy
L. Gramlich
D. Armstrong
J P Allard
Author Affiliation
University Health Network, Toronto General Hospital, Toronto, Ontario, Canada.
Source
JPEN J Parenter Enteral Nutr. 2012 Jul;36(4):407-14
Date
Jul-2012
Language
English
Publication Type
Article
Keywords
Bilirubin - blood
Canada
Female
Follow-Up Studies
Hospitalization
Humans
Liver Diseases - etiology - physiopathology
Male
Nutrition Assessment
Parenteral Nutrition, Home - adverse effects - methods
Potassium - blood
Quality of Life
Registries
Treatment Outcome
Abstract
In Canada, there are an estimated 400 home parenteral nutrition (HPN) patients. In 2006, a registry was created to gather patient outcome information. The aim of this study was to validate the registry and report on HPN patient outcomes.
Several demographic, clinical parameters were collected. For the validation, paired t test and intraclass correlation coefficient (ICC) were used to assess agreement between repeat entries. For the outcome report, paired t test was used to assess changes, and survival analysis was performed using the Kaplan-Meier method. Results are expressed as mean ± SEM.
On validation, there was high correlation/agreement (P
PubMed ID
22326909 View in PubMed
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Vitamin D deficiency in patients receiving home parenteral nutrition.

https://arctichealth.org/en/permalink/ahliterature134804
Source
JPEN J Parenter Enteral Nutr. 2011 Jul;35(4):499-504
Publication Type
Article
Date
Jul-2011
Author
Patti Thomson
Donald R Duerksen
Author Affiliation
Department of Medicine, Division of Gastroenterology, C5120 409 Tache Ave, St Boniface Hospital, Winnipeg, Manitoba, Canada. duerksn@cc.umanitoba.ca
Source
JPEN J Parenter Enteral Nutr. 2011 Jul;35(4):499-504
Date
Jul-2011
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Calcium, Dietary - administration & dosage
Canada
Dietary Supplements
Female
Humans
Male
Middle Aged
Parenteral Nutrition, Home - adverse effects - methods
Prevalence
Vitamin D - analogs & derivatives - blood
Vitamin D Deficiency - blood - epidemiology
Vitamins - blood
Young Adult
Abstract
In addition to its role in bone metabolism, vitamin D has important immunomodulatory and antineoplastic effects. Patients on home parenteral nutrition (HPN) receive most of their vitamin D from intravenous (IV) supplementation. Vitamin D deficiency is common in the general population, and the adequacy of vitamin D supplementation in HPN patients is unclear. The purpose of this study is to determine the vitamin D status of patients on HPN.
Consecutive patients seen in a regional home nutrition program had their oral and IV vitamin D intakes determined. Plasma 25-hydroxyvitamin D levels were measured in all patients. Intake of calcium, magnesium, and phosphate were also determined.
The mean 25-hydroxyvitamin D level in 22 patients receiving HPN for a mean of 33.5 months (range, 1-177) was 42 nmol/L. Vitamin D deficiency was present in 15 (68%) patients and vitamin D insufficiency in 6 (27%) patients. The mean dietary vitamin D intake was 79.5 IU per day, while the mean IV supplementation was 166 IU per day.
In this study of a regional Canadian HPN program, there was a high prevalence of vitamin D deficiency/insufficiency affecting virtually all patients. All patients receiving HPN should be supplemented with vitamin D and have their 25-hydroxyvitamin D levels monitored. Further studies are required to determine optimal methods and dosing of vitamin D replacement using oral supplements or ultraviolet light therapy.
PubMed ID
21540352 View in PubMed
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