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14658 records – page 1 of 1466.

A 2-year community-randomized controlled trial of fluoride varnish to prevent early childhood caries in Aboriginal children.

https://arctichealth.org/en/permalink/ahliterature157658
Source
Community Dent Oral Epidemiol. 2008 Dec;36(6):503-16
Publication Type
Article
Date
Dec-2008
Author
Herenia P Lawrence
Darlene Binguis
Jan Douglas
Lynda McKeown
Bonita Switzer
Rafael Figueiredo
Audrey Laporte
Author Affiliation
Community Dentistry Discipline, Department of Biological and Diagnostic Sciences, Faculty of Dentistry, University of Toronto, Toronto, ON, Canada. herenia.lawrence@utoronto.ca
Source
Community Dent Oral Epidemiol. 2008 Dec;36(6):503-16
Date
Dec-2008
Language
English
Publication Type
Article
Keywords
Caregivers - education
Cariostatic Agents - administration & dosage - therapeutic use
Child, Preschool
Cluster analysis
DMF Index
Dental Caries - epidemiology - prevention & control
Female
Fluorides, Topical - therapeutic use
Health Education, Dental
Health Status Disparities
Humans
Incidence
Indians, North American
Infant
Logistic Models
Male
Ontario - epidemiology
Prevalence
Sodium Fluoride - administration & dosage
Tooth, Deciduous
Abstract
To measure the effectiveness of fluoride varnish (FV) (Duraflor), 5% sodium fluoride, Pharmascience Inc., Montréal, QC, Canada) and caregiver counseling in preventing early childhood caries (ECC) in Aboriginal children in a 2-year community-randomized controlled trial.
Twenty First Nations communities in the Sioux Lookout Zone (SLZ), Northwest Ontario, Canada were randomized to two study groups. All caregivers received oral health counseling, while children in one group received FV twice per year and the controls received no varnish. A total of 1275, 6 months to 5-year-old children from the SLZ communities were enrolled. In addition, a convenience sample of 150 primarily non-Aboriginal children of the same age were recruited from the neighboring community of Thunder Bay and used as comparisons. Longitudinal examinations for the dmft/s indices were conducted by calibrated hygienists in 2003, 2004 and 2005.
Aboriginal children living in the SLZ or in Thunder Bay had significantly higher caries prevalence and severity than non-Aboriginal children in Thunder Bay. FV treatment conferred an 18% reduction in the 2-year mean 'net' dmfs increment for Aboriginal children and a 25% reduction for all children, using cluster analysis to adjust for the intra-cluster correlation among children in the same community. Adjusted odds ratio for caries incidence was 1.96 times higher in the controls than in the FV group (95% CI = 1.08-3.56; P = 0.027). For those caries-free at baseline, the number (of children) needed to treat (NNT) equaled 7.4.
Findings support the use of FV at least twice per year, in conjunction with caregiver counseling, to prevent ECC, reduce caries increment and oral health inequalities between young Aboriginal and non-Aboriginal children.
PubMed ID
18422711 View in PubMed
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The 2-year costs and effects of a public health nursing case management intervention on mood-disordered single parents on social assistance.

https://arctichealth.org/en/permalink/ahliterature191135
Source
J Eval Clin Pract. 2002 Feb;8(1):45-59
Publication Type
Article
Date
Feb-2002
Author
Maureen Markle-Reid
Gina Browne
Jacqueline Roberts
Amiram Gafni
Carolyn Byrne
Author Affiliation
System-Linked Research Unit on Health and Social Service Utilization, School of Nursing, McMaster University, Room 3N46, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5, Canada. mreid@mcmaster.ca
Source
J Eval Clin Pract. 2002 Feb;8(1):45-59
Date
Feb-2002
Language
English
Publication Type
Article
Keywords
Adaptation, Psychological
Adult
Case Management - economics
Child
Cost-Benefit Analysis
Depressive Disorder - economics - nursing - rehabilitation
Employment
Female
Health Care Costs
Health Services - utilization
Health Services Accessibility
Humans
Male
Ontario
Public Assistance
Public Health Nursing - economics
Single Parent - psychology
Social Adjustment
Abstract
This randomized controlled trial was designed to evaluate the 2-year costs and effects of a proactive, public health nursing case management approach compared with a self-directed approach for 129 single parents (98% were mothers) on social assistance in a Canadian setting. A total of 43% of these parents had a major depressive disorder and 38% had two or three other health conditions at baseline.
Study participants were recruited over a 12 month period and randomized into two groups: one receiving proactive public health nursing and one which did not.
At 2 years, 69 single parents with 123 children receiving proactive public health nursing (compared with 60 parents with 91 children who did not receive public health nursing services) showed a slightly greater reduction in dysthymia and slightly higher social adjustment. There was no difference between the public health and control groups in total per parent annual cost of health and support services. However, costs were averted due to a 12% difference in non-use of social assistance in the previous 12 months for parents in the public health nursing group. This translates into an annual cost saving of 240,000 dollars (Canadian) of costs averted within 1 year for every 100 parents.
In the context of a system of national health and social insurance, this study supports the fact that it is no more costly to proactively service this population of parents on social assistance.
PubMed ID
11882101 View in PubMed
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4-aminopyridine toxicity with unintentional overdose in four patients with multiple sclerosis.

https://arctichealth.org/en/permalink/ahliterature154078
Source
Neurology. 2008 Nov 25;71(22):1833-4
Publication Type
Article
Date
Nov-25-2008

A 4-year review of severe pediatric trauma in eastern Ontario: a descriptive analysis.

https://arctichealth.org/en/permalink/ahliterature191929
Source
J Trauma. 2002 Jan;52(1):8-12
Publication Type
Article
Date
Jan-2002
Author
Martin H Osmond
Maureen Brennan-Barnes
Allyson L Shephard
Author Affiliation
Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada. osmond@cheo.on.ca
Source
J Trauma. 2002 Jan;52(1):8-12
Date
Jan-2002
Language
English
Publication Type
Article
Keywords
Accident prevention
Accidental Falls - prevention & control - statistics & numerical data
Accidents, Traffic - prevention & control - statistics & numerical data
Adolescent
Age Distribution
Athletic Injuries - epidemiology - etiology - prevention & control
Child
Child Abuse - prevention & control - statistics & numerical data
Child, Preschool
Craniocerebral Trauma - epidemiology - etiology - prevention & control
Female
Hospitals, Pediatric - statistics & numerical data
Humans
Infant
Infant, Newborn
Male
Ontario - epidemiology
Retrospective Studies
Sex Distribution
Time Factors
Trauma Centers - statistics & numerical data
Trauma Severity Indices
Wounds and Injuries - epidemiology - etiology - prevention & control
Abstract
The objective of this study was to describe a population of children admitted to a tertiary care pediatric hospital with severe trauma to identify key areas for injury prevention research, and programming.
Retrospective chart review conducted on all children 0-17 years admitted to the Children's Hospital of Eastern Ontario (CHEO) between April 1, 1996, and March 31, 2000, following acute trauma. Each record was reviewed and assigned an ISS using the AIS 1990 revision. All cases with an ISS > 11 were included in the study.
There were 2610 trauma cases admitted to CHEO over the study period. Of these, 237 (9.1%) had severe trauma (ISS > 11). Sixty-two percent were male. Twenty-nine percent were between the ages of 10 and 14 years, 27% between 5 and 9 years, 16% between 15 and 17 years, 15% between 1 and 4 years, and 13% less than 1 year old. The most common mechanisms of injury were due to motor vehicle traffic (39%), falls (24%), child abuse (8%), and sports (5%). Of those resulting from motor vehicle traffic, 53 (57%) were occupants, 22 (24%) were pedestrians, and 18 (19%) were cyclists. When combining traffic and nontraffic mechanisms, 26 (11% of all severe trauma cases) occurred as a result of cycling incidents. The most severe injury in 65% of patients was to the head and neck body region.
Research efforts and activities to prevent severe pediatric trauma in our region should focus on road safety, protection from head injuries, avoidance of falls, and prevention of child abuse.
PubMed ID
11791045 View in PubMed
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5-year review of a unique multidisciplinary nonmelanoma skin cancer clinic.

https://arctichealth.org/en/permalink/ahliterature132764
Source
J Cutan Med Surg. 2011 Jul-Aug;15(4):220-6
Publication Type
Article
Author
Shaelyn Culleton
Dale Breen
Dalal Assaad
Liying Zhang
Judith Balogh
May Tsao
Juhu Kamra
Greg Czarnota
Oleh Antonyshyn
Jeffery Fialkov
Elizabeth Barnes
Author Affiliation
Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada.
Source
J Cutan Med Surg. 2011 Jul-Aug;15(4):220-6
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Aged, 80 and over
Biopsy
Carcinoma, Basal Cell - pathology - therapy
Carcinoma, Squamous Cell - pathology - therapy
Chi-Square Distribution
Child
Delivery of Health Care, Integrated - organization & administration
Female
Humans
Male
Middle Aged
Ontario
Outcome and Process Assessment (Health Care)
Skin Neoplasms - pathology - therapy
Abstract
A multidisciplinary nonmelanoma skin cancer (NMSC) clinic is held weekly at our center, where all new patients are jointly assessed by dermatology/dermatopathology, radiation oncology, and plastic surgery. A new patient database was established in 2004. The purpose of this study was to provide a preliminary report on the patients seen in the NMSC clinic and the treatment recommendations rendered.
The new patient database was reviewed from January 2004 to December 2008, and patient demographics, tumor characteristics, and treatment recommendations were extracted. Cochran-Mantel-Harnszel (CMH) testing and chi-square analysis were used to detect any associations or relationships between variables within the database. A p value of less than .05 was considered significant.
During the 5-year study period, 2,146 new patients were seen in the NMSC clinic. The majority of patients presented with basal cell carcinoma (64%) or squamous cell carcinoma (22%), with a median tumor size of 1 to 2 cm (range 0 to > 9 cm). Tumors were located in the head and neck region (80%), extremities (14%), and torso (6%). Previous treatment included biopsy only (62%), surgery (20%), electrodesiccation and curettage (11%), topical imiquimod (3%), and radiotherapy (1%). Treatment recommendations included surgery (55%) (with either simple excision [31%] or excision with margin control under frozen-section guidance [24%]), radiotherapy (19%), topical imiquimod (10%), observation (7%), and electrodesiccation and curettage (4%).
The NMSC clinic at our center sees a high volume of patients who benefit from the multidisciplinary assessment provided. Treatment recommendations were based on patient and disease characteristics as well as patient preference.
PubMed ID
21781628 View in PubMed
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The 6-min walk test: responses in healthy Canadians aged 45 to 85 years.

https://arctichealth.org/en/permalink/ahliterature130789
Source
Appl Physiol Nutr Metab. 2011 Oct;36(5):643-9
Publication Type
Article
Date
Oct-2011
Author
Kylie Hill
Lisa M Wickerson
Lynda J Woon
Afshin Heidar Abady
Tom J Overend
Roger S Goldstein
Dina Brooks
Author Affiliation
Department of Respirology, West Park Healthcare Centre, Toronto, Ontario, Canada.
Source
Appl Physiol Nutr Metab. 2011 Oct;36(5):643-9
Date
Oct-2011
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Algorithms
Exercise Test
Female
Heart rate
Humans
Male
Middle Aged
Ontario
Oxygen consumption
Physical Fitness
Reference Values
Reproducibility of Results
Respiration
Respiratory Rate
Sex Characteristics
Tidal Volume
Time Factors
Walking
Abstract
We sought to describe responses to the 6-min walk test (6MWT) in healthy Canadian adults in order to facilitate interpretation of its results in patient populations. Seventy-seven healthy Canadians aged 45 to 85 years (65 ± 11 years, 40 females) completed this study. During a single visit, three 6MWTs were undertaken. The main outcome measure was 6-min walk distance (6MWD). Age, gender, height, and weight were recorded. In 61 (79%) participants, cardiorespiratory variables were collected during the third 6MWT using a calibrated portable gas analysis system. The 6MWD increased between the first and second test (615 ± 96 to 639 ± 98 m; p
PubMed ID
21967531 View in PubMed
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A 7-year retrospective review from 2005 to 2011 of Propionibacterium acnes shoulder infections in Ottawa, Ontario, Canada.

https://arctichealth.org/en/permalink/ahliterature117999
Source
Diagn Microbiol Infect Dis. 2013 Feb;75(2):195-9
Publication Type
Article
Date
Feb-2013
Author
Bing Wang
Baldwin Toye
Marc Desjardins
Peter Lapner
Craig Lee
Author Affiliation
Division of Microbiology, Department of Pathology and Laboratory Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada.
Source
Diagn Microbiol Infect Dis. 2013 Feb;75(2):195-9
Date
Feb-2013
Language
English
Publication Type
Article
Keywords
Adult
Aged
Arthroplasty
Chi-Square Distribution
Female
Gram-Positive Bacterial Infections - epidemiology - microbiology
Humans
Joint Diseases - epidemiology - microbiology
Male
Middle Aged
Ontario - epidemiology
Propionibacterium acnes - isolation & purification
Prosthesis-Related Infections - epidemiology - microbiology
Retrospective Studies
Shoulder Joint - microbiology
Abstract
This study evaluated the clinical factors associated with Propionibacterium acnes shoulder infection and the standard culture procedures for isolating P. acnes from shoulder specimens by a 7-year retrospective analysis. P. acnes was incriminated as the second most common pathogen in 17 of 80 patients with positive shoulder cultures. All of the 17 patients had prior shoulder implant. The cumulative rates for isolating P. acnes were 1.9%, 1.9%, 41.9%, 96.4%, and 100% at day 1 to day 5 of incubation, respectively. The standard practice of anaerobic culture was able to detect P. acnes from shoulder specimens in patients with a clinical suspicion of infection. The sensitivity and specificity of prolonged incubation remain to be determined.
PubMed ID
23246074 View in PubMed
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8th Annual Toronto Critical Care Medicine Symposium, 30 October-1 November 2003, Toronto, Ontario, Canada.

https://arctichealth.org/en/permalink/ahliterature181450
Source
Crit Care. 2004 Feb;8(1):58-66
Publication Type
Conference/Meeting Material
Date
Feb-2004
Author
Jeff Granton
John Granton
Author Affiliation
Programme Director, Critical Care Medicine Programme, University of Toronto, Canada. john.Granton@uhn.on.ca
Source
Crit Care. 2004 Feb;8(1):58-66
Date
Feb-2004
Language
English
Publication Type
Conference/Meeting Material
Keywords
Blood Transfusion - adverse effects - utilization
Critical Care
Cross Infection - epidemiology
Humans
Intensive Care Units
Ontario - epidemiology
Respiration, Artificial
Sepsis - therapy
Severe Acute Respiratory Syndrome - epidemiology
Terminal Care
Notes
Cites: J Immunol. 2000 Sep 15;165(6):2950-410975801
Cites: Crit Care Med. 1994 Oct;22(10):1568-787924367
Cites: J Palliat Care. 2000 Oct;16 Suppl:S45-5211075533
Cites: Anaesthesia. 2001 Feb;56(2):124-911167472
Cites: Intensive Care Med. 2001 Feb;27(2):355-6211396279
Cites: Am J Respir Crit Care Med. 2001 Aug 1;164(3):396-40211500339
Cites: J Clin Microbiol. 2001 Oct;39(10):3727-3211574603
Cites: Neurology. 2002 Jan 8;58(1):20-511781400
Cites: Am J Respir Crit Care Med. 2002 Jan 15;165(2):165-7011790648
Cites: Anesthesiology. 2002 Apr;96(4):795-80211964585
Cites: Lancet. 2002 Jul 20;360(9328):219-2312133657
Cites: Gastroenterology. 2002 Sep;123(3):790-80212198705
Cites: Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12351-612209006
Cites: JAMA. 2002 Sep 25;288(12):1499-50712243637
Cites: Intensive Care Med. 2003 Jan;29(1):55-6112528023
Cites: Am J Respir Crit Care Med. 2003 Feb 15;167(4):521-712493644
Cites: N Engl J Med. 2003 Feb 20;348(8):683-9312594312
Cites: Intensive Care Med. 2003 Mar;29(3):481-312560869
Cites: CMAJ. 2003 Apr 15;168(8):993-512695383
Cites: JAMA. 2003 Apr 16;289(15):1941-912697796
Cites: JAMA. 2003 Apr 16;289(15):1950-612697797
Cites: JAMA. 1995 Mar 1;273(9):703-87853627
Cites: Shock. 1994 Apr;1(4):246-537735958
Cites: Chest. 1995 Sep;108(3):767-717656631
Cites: N Engl J Med. 1996 May 30;334(22):1417-218618579
Cites: J Appl Physiol (1985). 1995 Dec;79(6):1878-828847247
Cites: Am J Respir Crit Care Med. 1996 Jul;154(1):57-628680699
Cites: Intensive Care Med. 1996 May;22(5):387-948796388
Cites: Crit Care Med. 1997 Mar;25(3):435-99118659
Cites: Lancet. 1997 Jul 26;350(9073):251-59242802
Cites: Crit Care Med. 1998 Jan;26(1):44-99428542
Cites: Am J Respir Crit Care Med. 1998 Feb;157(2):371-69476845
Cites: Chest. 1998 Feb;113(2):412-209498961
Cites: Intensive Care Med. 1998 Feb;24(2):172-79539077
Cites: Am J Respir Crit Care Med. 1998 Jun;157(6 Pt 1):1721-59620897
Cites: JAMA. 1999 Jan 13;281(2):163-89917120
Cites: Am J Respir Crit Care Med. 1999 Mar;159(3):872-8010051265
Cites: Am J Respir Crit Care Med. 1999 Apr;159(4 Pt 1):1249-5610194173
Cites: Chest. 1999 Apr;115(4):1076-8410208211
Cites: Science. 1999 Jul 9;285(5425):248-5110398600
Cites: Crit Care Med. 1999 Jul;27(7):1230-5110446814
Cites: Nat Med. 1999 Dec;5(12):1433-610581089
Cites: Intensive Care Med. 1999 Nov;25(11):1297-30110654217
Cites: Crit Care Med. 2000 May;28(5):1269-7510834664
Cites: Am J Respir Crit Care Med. 2000 Jul;162(1):27-3310903215
Cites: Am J Respir Crit Care Med. 2000 Jul;162(1):119-2510903230
Cites: Crit Care Med. 2000 Aug;28(8):2737-4110966244
Cites: N Engl J Med. 2003 May 29;348(22):2196-20312773646
Cites: Am J Respir Crit Care Med. 2003 Jun 15;167(12):1633-4012663325
Cites: Intensive Care Med. 2003 Jun;29(6):870-512739014
Cites: Lancet. 2003 Jun 14;361(9374):2068-7712814731
Cites: Br J Anaesth. 2003 Jul;91(1):61-7212821566
Cites: Chest. 2003 Jul;124(1):392-712853551
Cites: JAMA. 2003 Jul 16;290(3):367-7312865378
Cites: Surgery. 2003 Aug;134(2):180-812947316
Cites: Pediatrics. 2003 Sep;112(3 Pt 1):553-812949283
Cites: N Engl J Med. 2003 Sep 18;349(12):1123-3213679526
Cites: Am J Clin Pathol. 1989 Jun;91(6):701-32729182
Cites: Intensive Care Med. 1990;16(6):372-72246418
Cites: Crit Care Med. 1993 Jul;21(7):1012-98319458
Cites: Am J Crit Care. 1992 Jul;1(1):85-901307883
Cites: J Palliat Care. 2000 Oct;16 Suppl:S31-911075531
PubMed ID
14975048 View in PubMed
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A 10 mg warfarin initiation nomogram is safe and effective in outpatients starting oral anticoagulant therapy for venous thromboembolism.

https://arctichealth.org/en/permalink/ahliterature153058
Source
Thromb Res. 2009 Jul;124(3):275-80
Publication Type
Article
Date
Jul-2009
Author
Katherine Monkman
Alejandro Lazo-Langner
Michael J Kovacs
Author Affiliation
Department of Medicine, Division of Hematology, University of Western Ontario, London, Ontario, Canada.
Source
Thromb Res. 2009 Jul;124(3):275-80
Date
Jul-2009
Language
English
Publication Type
Article
Keywords
Administration, Oral
Adolescent
Adult
Aged
Aged, 80 and over
Ambulatory Care - methods
Anticoagulants - administration & dosage
Comorbidity
Dose-Response Relationship, Drug
Female
Hemorrhage - mortality
Humans
Incidence
Male
Middle Aged
Ontario - epidemiology
Retrospective Studies
Survival Rate
Treatment Outcome
Venous Thromboembolism - drug therapy - mortality
Warfarin - administration & dosage
Young Adult
Abstract
The optimal means of initiating warfarin therapy for acute venous thromboembolism in the outpatient setting remains controversial. We have previously demonstrated the efficacy of a 10 mg initiation nomogram in a randomized controlled trial; however, some clinicians remain reluctant to use this nomogram due to a fear of potential increased bleeding. To review the safety and efficacy of a 10 mg warfarin nomogram we conducted a retrospective cohort study of patients prospectively treated for venous thromboembolism according to a 10 mg nomogram in an outpatient thrombosis clinic. All patients received standard treatment with low molecular weight heparin for 5 to 7 days and warfarin for at least 3 months. Four-hundred and fourteen patients were included in the analysis, of whom 295 (71%) fully adhered to the nomogram. In the whole cohort, 8 patients (1.9%) experienced recurrent thrombosis, 4 (0.97%) suffered a major bleeding event, and 3 (0.72%) suffered a minor bleeding event. There were no deaths related to thrombosis or bleeding. Four patients (0.97%) died from unrelated causes. Twenty-two (5.3%) patients experienced an INR > or =5.0 in the first 8 days of therapy, and none of these patients experienced a bleeding event. Eighty-four percent of patients achieved a therapeutic INR by day 5. In outpatients, a 10 mg nomogram results in timely achievement of a therapeutic INR with an acceptable incidence of bleeding and recurrent thromboembolism.
PubMed ID
19155056 View in PubMed
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14658 records – page 1 of 1466.