The aim of this study was to determine the level of risk of occupational cancer among compositors exposed to inorganic lead. A total of 216 men and 423 women were included in the cohort and followed up from 1 January 1979 to 31 December 1993. There were 2759 person-years among males and 6050 person-years among females. Among men, employed as compositors, there was a significantly elevated mortality from pancreas cancer. We have found two deaths from kidney cancer occurred exclusively among women-compositors with exposure 20 years or more yielding significantly increased SMR of 10.0.
The paper presents the findings of the first Russian study of possible cancer risks in printing workers. For the first time, the historical cohort study included women. The cohort comprised 1,553 males and 3,473 females who were followed up for 15 years (01/01/79-12/31/93). A significant increase in the rates of death from pancreatic cancer was registered among males employed as compositors exposed to inorganic lead dust and vapors. Raised mortality from malignancies of the stomach urinary bladder, skin melanoma and mesothelioma was identified in females exposed to a PAU-containing oil paint aerosol and paper dust. Significant death risks from esophageal and ovarian malignancies due to exposure to glue vapors and paper dust were observed in bookbinders.