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The presentation of adrenarche is sexually dimorphic and modified by body adiposity.

https://arctichealth.org/en/permalink/ahliterature259848
Source
J Clin Endocrinol Metab. 2014 Oct;99(10):3889-94
Publication Type
Article
Date
Oct-2014
Author
Aino Mäntyselkä
Jarmo Jääskeläinen
Virpi Lindi
Anna Viitasalo
Tuomo Tompuri
Raimo Voutilainen
Timo A Lakka
Source
J Clin Endocrinol Metab. 2014 Oct;99(10):3889-94
Date
Oct-2014
Language
English
Publication Type
Article
Keywords
Adipose Tissue - physiology
Adiposity - physiology
Adrenal Cortex - growth & development - metabolism
Adrenarche - physiology
Androgens - blood
Body Composition - physiology
Child
Cross-Sectional Studies
Dehydroepiandrosterone Sulfate - blood
Female
Finland - epidemiology
Humans
Male
Obesity - epidemiology - metabolism
Prevalence
Puberty, Precocious - epidemiology - metabolism
Risk factors
Sex Characteristics
Abstract
Adrenarche refers to the onset of increased production of adrenal androgens in childhood leading variably to clinical signs of androgen action. The prevalence and presentation of adrenarche in prepubertal girls and boys is not well known.
Our objective was to examine the prevalence and clinical presentation of adrenarche in a population sample of prepubertal children aged less than 9 years.
This cross-sectional study included prepubertal children (209 girls and 228 boys; median age 7.6 [range 6.8-8.9] years) taking part in The Physical Activity and Nutrition in Children (PANIC) Study.
The prevalence of adrenarche was assessed.
The prevalence of any clinical sign of androgen action was higher in girls than in boys (26.1% vs 10.0%; P
PubMed ID
25029425 View in PubMed
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