Overall 1580 children from the regions with unsafe radiation situation were examined comprehensively at different times after the accident. The data obtained were correlated to the results of examining 610 children of the control group. The basic group children manifested a higher incidence of diverse alterations on the part of many organs and systems, which was accompanied by an increase of free radical processes signs of destabilization of cellular membranes, activation of blood cell metabolism, suppression of the T cell component of immunity in the presence of vegetovascular dysfunction. A tendency was noted toward normalization of these alterations seen over time after the accident. No clear-cut dose-effect dependence was found.
[The clinical and cytogenetic characteristics of the children born to persons with a history of 1st- and 2d-degree acute radiation sickness as a result of the accident at the Chernobyl Atomic Electric Power Station]
We have examined 15 children (born in 1987-1988), whose fathers liquidated the aftereffects of the accident at Chernobyl Nuclear Power Plant and suffered from acute radiation sickness of the 1st and 2nd stages and 50 children of the control group. The obtained data showed that the number of small developmental abnormalities (stigmas of dysembryogenesis) increased as well as the chromatid aberration frequency as compared with the control group.
A total of 878 children from the regions with unfavourable radiation situation were investigated in varying periods after the catastrophe. The data obtained were compared with the results of the study of 317 children from "pure" regions. Morphological, metabolic and ultrastructural changes were detected in blood cells of the children from radioactively contaminated regions after the Chernobyl catastrophe. A tendency to normalization of these parameters was noted in the time course of the post-catastrophe period. No clear relationship was established between the dose and effect. However, significant correlations between the severity of disorders in blood cells and the intensity of free-radical processes in the body were recorded.